Persistence ofToxoplasma gondiiin the central nervous system: a fine-tuned balance between the parasite, the brain and the immune system

Differentiation of Type 1 ILCs from a Common Progenitor to All Helper-like Innate Lymphoid Cell Lineages

(2014) Christoph S.N. Klose et al.   CELL

VCAM-1/α4β1 Integrin Interaction Is Crucial for Prompt Recruitment of Immune T Cells into the Brain during the Early Stage of Reactivation of Chronic Infection with Toxoplasma gondii To Prevent Toxoplasmic Encephalitis

(2014) Qila Sa et al.   INFECTION AND IMMUNITY

Collective nitric oxide production provides tissue-wide immunity during Leishmania infection

(2014) Romain Olekhnovitch et al.   JOURNAL OF CLINICAL INVESTIGATION

Astrocyte gp130 Expression Is Critical for the Control of Toxoplasma Encephalitis

(2014) K. Drogemuller et al.   JOURNAL OF IMMUNOLOGY

Astrocytic TGF-  Signaling Limits Inflammation and Reduces Neuronal Damage during Central Nervous System Toxoplasma Infection

(2014) E. Cekanaviciute et al.   JOURNAL OF IMMUNOLOGY

Ocular toxoplasmosis past, present and new aspects of an old disease

(2014) M. Maenz et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Impact of Regulated Secretion on Antiparasitic CD8 T Cell Responses

(2014) Harshita Satija Grover et al.   Cell Reports

Extracellular Vesicle-Mediated Transfer of Genetic Information between the Hematopoietic System and the Brain in Response to Inflammation

(2014) Kirsten Ridder et al.   PLOS BIOLOGY

Parasite Fate and Involvement of Infected Cells in the Induction of CD4+ and CD8+ T Cell Responses to Toxoplasma gondii

(2014) Christopher D. Dupont et al.   PLoS Pathogens

Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection

(2013) John R Grainger et al.   NATURE MEDICINE

A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

(2013) Tobias Goldmann et al.   NATURE NEUROSCIENCE

Location of the CD8 T Cell Epitope within the Antigenic Precursor Determines Immunogenicity and Protection against the Toxoplasma gondii Parasite

(2013) Virginie Feliu et al.   PLoS Pathogens

Guanylate-binding Protein 1 (Gbp1) Contributes to Cell-autonomous Immunity against Toxoplasma gondii

(2013) Elizabeth M. Selleck et al.   PLoS Pathogens

Neuronal gp130 Expression Is Crucial to Prevent Neuronal Loss, Hyperinflammation, and Lethal Course of Murine Toxoplasma Encephalitis

(2012) Ulrike Händel et al.   AMERICAN JOURNAL OF PATHOLOGY

The Toxoplasma gondii Peptide AS15 Elicits CD4 T Cells That Can Control Parasite Burden

(2012) Harshita Satija Grover et al.   INFECTION AND IMMUNITY

PD-1–Mediated Attrition of Polyfunctional Memory CD8+ T Cells in Chronic Toxoplasma Infection

(2012) Rajarshi Bhadra et al.   JOURNAL OF INFECTIOUS DISEASES

Harnessing monocyte-derived macrophages to control central nervous system pathologies: no longer ‘if’ but ‘how’

(2012) Ravid Shechter et al.   JOURNAL OF PATHOLOGY

Toxoplasma gondii Actively Inhibits Neuronal Function in Chronically Infected Mice

(2012) Fahad Haroon et al.   PLoS One

Murine Guanylate Binding Protein 2 (mGBP2) controls Toxoplasma gondii replication

(2012) D. Degrandi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chitinase Dependent Control of Protozoan Cyst Burden in the Brain

(2012) J. Philip Nance et al.   PLoS Pathogens

CD8α+ Dendritic Cells Are the Critical Source of Interleukin-12 that Controls Acute Infection by Toxoplasma gondii Tachyzoites

(2011) Mona Mashayekhi et al.   IMMUNITY

The CD40-Autophagy Pathway Is Needed for Host Protection Despite IFN-Γ-Dependent Immunity and CD40 Induces Autophagy via Control of P21 Levels

(2011) Jose-Andres C. Portillo et al.   PLoS One

Subcellular Antigen Location Influences T-Cell Activation during Acute Infection with Toxoplasma gondii

(2011) Beth Gregg et al.   PLoS One

Control of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade

(2011) R. Bhadra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of Behavior and Trafficking of Dendritic Cells within the Brain during Toxoplasmic Encephalitis

(2011) Beena John et al.   PLoS Pathogens

Inflammatory Monocytes but Not Neutrophils Are Necessary To Control Infection with Toxoplasma gondii in Mice

(2010) I. R. Dunay et al.   INFECTION AND IMMUNITY

Transnuclear Mice with Predefined T Cell Receptor Specificities Against Toxoplasma gondii Obtained via SCNT

(2010) O. Kirak et al.   SCIENCE

Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondii

(2010) Tobias Steinfeldt et al.   PLOS BIOLOGY

Differential Regulation of Effector- and Central-Memory Responses to Toxoplasma gondii Infection by IL-12 Revealed by Tracking of Tgd057-Specific CD8+ T Cells

(2010) Douglas C. Wilson et al.   PLoS Pathogens

Behavior of Parasite-Specific Effector CD8+ T Cells in the Brain and Visualization of a Kinesis-Associated System of Reticular Fibers

(2009) Emma H. Wilson et al.   IMMUNITY

Selective Expansion of the Monocytic Lineage Directed by Bacterial Infection

(2009) N. V. Serbina et al.   JOURNAL OF IMMUNOLOGY

Dynamic Imaging of T Cell-Parasite Interactions in the Brains of Mice Chronically Infected with Toxoplasma gondii

(2009) Marie Schaeffer et al.   JOURNAL OF IMMUNOLOGY

Gr1+ Inflammatory Monocytes Are Required for Mucosal Resistance to the Pathogen Toxoplasma gondii

(2008) Ildiko R. Dunay et al.   IMMUNITY

The Gamma Interferon (IFN- )-Inducible GTP-Binding Protein IGTP Is Necessary for Toxoplasma Vacuolar Disruption and Induces Parasite Egression in IFN- -Stimulated Astrocytes

(2008) T. Melzer et al.   INFECTION AND IMMUNITY

Parasite Stage–Specific Recognition of EndogenousToxoplasma gondii–Derived CD8+T Cell Epitopes

(2008) Eva‐Maria Frickel et al.   JOURNAL OF INFECTIOUS DISEASES

Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum

(2008) Nicolas Blanchard et al.   NATURE IMMUNOLOGY