Role of the IL-1 Pathway in Dopaminergic Neurodegeneration and Decreased Voluntary Movement

Infiltration of circulating myeloid cells through CD95L contributes to neurodegeneration in mice

(2015) Liang Gao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neuroprotective effects of vildagliptin in rat rotenone Parkinson's disease model: role of RAGE-NFκB and Nrf2-antioxidant signaling pathways

(2015) Rania M. Abdelsalam et al.   JOURNAL OF NEUROCHEMISTRY

Anti-inflammatory effects of BHBA in both in vivo and in vitro Parkinson’s disease models are mediated by GPR109A-dependent mechanisms

(2015) Shou-Peng Fu et al.   Journal of Neuroinflammation

Temporal Gene Expression in the Hippocampus and Peripheral Organs to Endotoxin-Induced Systemic Inflammatory Response in Caspase-1-Deficient Mice

(2015) Claudio Alberto Mastronardi et al.   NEUROIMMUNOMODULATION

Saxagliptin: A novel antiparkinsonian approach

(2015) Noha N. Nassar et al.   NEUROPHARMACOLOGY

Neuroprotective effects of lixisenatide and liraglutide in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease

(2015) W. Liu et al.   NEUROSCIENCE

Neuroprotective intervention by interferon-γ blockade prevents CD8+T cell–mediated dendrite and synapse loss

(2013) Mario Kreutzfeldt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activation of microglia induces symptoms of Parkinson’s disease in wild-type, but not in IL-1 knockout mice

(2013) Sachiko Tanaka et al.   Journal of Neuroinflammation

Measuring Motor Coordination in Mice

(2013) Robert M.J. Deacon   Jove-Journal of Visualized Experiments

Clinical application of stem cell therapy in Parkinson's disease

(2012) Marios Politis et al.   BMC Medicine

Optimal Dosages of Fluoxetine in the Treatment of Hypoxic Brain Injury Induced by 3-Nitropropionic Acid: Implications for the Adjunctive Treatment of Patients after Acute Ischemic Stroke

(2012) Bing-Gen Zhu et al.   CNS Neuroscience & Therapeutics

Contributions of central and systemic inflammation to the pathophysiology of Parkinson's disease

(2012) Louise M. Collins et al.   NEUROPHARMACOLOGY

A clinical perspective of IL-1β as the gatekeeper of inflammation

(2011) Charles A. Dinarello   EUROPEAN JOURNAL OF IMMUNOLOGY

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

Nigral neurodegeneration triggered by striatal AdIL-1 administration can be exacerbated by systemic IL-1 expression

(2010) María Clara Pott Godoy et al.   JOURNAL OF NEUROIMMUNOLOGY

Ten years of Nature Reviews Neuroscience: insights from the highly cited

(2010) Liqun Luo et al.   NATURE REVIEWS NEUROSCIENCE

Anti-inflammatory drugs and risk of Parkinson disease: A meta-analysis

(2010) J. J. Gagne et al.   NEUROLOGY

Cytosolic labile zinc accumulation in degenerating dopaminergic neurons of mouse brain after MPTP treatment

(2009) Joo-Yong Lee et al.   BRAIN RESEARCH

Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice

(2009) Fangfang Yin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Relationship between microglial activation and dopaminergic neuronal loss in the substantia nigra: a time course study in a 6-hydroxydopamine model of Parkinson’s disease

(2009) Lilia Marinova-Mutafchieva et al.   JOURNAL OF NEUROCHEMISTRY

Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention

(2009) Malú G. Tansey et al.   NEUROBIOLOGY OF DISEASE

Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system

(2008) Ryan N. Dilger et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective

(2008) Solomon S Shaftel et al.   Journal of Neuroinflammation

Endotoxin induces a delayed loss of TH-IR neurons in substantia nigra and motor behavioral deficits

(2008) Yuxin Liu et al.   NEUROTOXICOLOGY