Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer

MicroRNA-139 modulates Alzheimer’s-associated pathogenesis in SAMP8 mice by targeting cannabinoid receptor type 2

(2017) Y. Tang et al.   GENETICS AND MOLECULAR RESEARCH

Mitochondrial dysfunction induces dendritic loss via eIF2α phosphorylation

(2017) Taiichi Tsuyama et al.   JOURNAL OF CELL BIOLOGY

MiR-107 is Reduced in Alzheimer's Disease Brain Neocortex: Validation Study

(2017) Peter T. Nelson et al.   JOURNAL OF ALZHEIMERS DISEASE

Seroprevalence and Serointensity of Latent Toxoplasma gondii in a Sample of Elderly Adults With and Without Alzheimer Disease

(2016) Cynthia E. Perry et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Temporal Cognitive Decline Associated With Exposure to Infectious Agents in a Population-based, Aging Cohort

(2016) Vishwajit L. Nimgaonkar et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Genetic Mapping of Pathogenesis Determinants inToxoplasma gondii

(2016) Michael S. Behnke et al.   Annual Review of Microbiology

Nedd8 targets ubiquitin ligase Smurf2 for neddylation and promote its degradation

(2016) Jingyi Shu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ubiquitin modifications

(2016) Kirby N Swatek et al.   CELL RESEARCH

Impact of Ataxin-2 knock out on circadian locomotor behavior and PER immunoreaction in the SCN of mice

(2016) Martina Pfeffer et al.   CHRONOBIOLOGY INTERNATIONAL

Functional Subclone Profiling for Prediction of Treatment-Induced Intratumor Population Shifts and Discovery of Rational Drug Combinations in Human Glioblastoma

(2016) Roman Reinartz et al.   CLINICAL CANCER RESEARCH

Understanding Toxoplasmosis in the United States Through “Large Data” Analyses

(2016) Joseph Lykins et al.   CLINICAL INFECTIOUS DISEASES

Morbid attraction to leopard urine in Toxoplasma-infected chimpanzees

(2016) Clémence Poirotte et al.   CURRENT BIOLOGY

Toxoplasma gondii Infection

(2016) Emil F. Coccaro et al.   JOURNAL OF CLINICAL PSYCHIATRY

Transcriptional profile of SH-SY5Y human neuroblastoma cells transfected by Toxoplasma rhoptry protein 16

(2016) Weiwei Fan et al.   Molecular Medicine Reports

Cullin–RING ubiquitin E3 ligase regulation by the COP9 signalosome

(2016) Simone Cavadini et al.   NATURE

Epilepsy, amyloid-β, and D1 dopamine receptors: a possible pathogenetic link?

(2016) Cinzia Costa et al.   NEUROBIOLOGY OF AGING

Toxoplasmosis and Alzheimer: can Toxoplasma gondii really be introduced as a risk factor in etiology of Alzheimer?

(2016) Mahmoud Mahami-Oskouei et al.   PARASITOLOGY RESEARCH

The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring

(2016) G. B. Choi et al.   SCIENCE

Maternal TH17 cells take a toll on baby's brain

(2016) M. L. Estes et al.   SCIENCE

RNA splicing is a primary link between genetic variation and disease

(2016) Yang I. Li et al.   SCIENCE

Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer’s disease

(2016) Deepak Kumar Vijaya Kumar et al.   Science Translational Medicine

Functional Analysis of the Rhoptry Kinome during Chronic Toxoplasma gondii Infection

(2016) Laura J. Knoll   mBio

The Rise of FXR1: Escaping Cellular Senescence in Head and Neck Squamous Cell Carcinoma

(2016) Erlinda Fernández et al.   PLoS Genetics

GLT-1-Dependent Disruption of CNS Glutamate Homeostasis and Neuronal Function by the Protozoan Parasite Toxoplasma gondii

(2016) Clément N. David et al.   PLoS Pathogens

Toxoplasma gondii peptide ligands open the gate of the HLA class I binding groove

(2016) Curtis McMurtrey et al.   eLife

Diagnostic workup and management of patients with suspected Niemann-Pick type C disease

(2016) Apostolos Papandreou et al.   Therapeutic Advances in Neurological Disorders

Is Toxoplasma Gondii Infection Related to Brain and Behavior Impairments in Humans? Evidence from a Population-Representative Birth Cohort

(2016) Karen Sugden et al.   PLoS One

New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections

(2016) Martin McPhillie et al.   Scientific Reports

Clustering ofToxoplasma gondiiInfections Within Families of Congenitally Infected Infants

(2015) Despina Contopoulos-Ioannidis et al.   CLINICAL INFECTIOUS DISEASES

WDFY1 mediates TLR3/4 signaling by recruiting TRIF

(2015) Y.-H. Hu et al.   EMBO REPORTS

Decoding the genetic basis of Cushing's disease: USP8 in the spotlight

(2015) Marily Theodoropoulou et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

GFAP and vimentin deficiency alters gene expression in astrocytes and microglia in wild-type mice and changes the transcriptional response of reactive glia in mouse model for Alzheimer's disease

(2015) Willem Kamphuis et al.   GLIA

Neurobiological studies on the relationship between toxoplasmosis and neuropsychiatric diseases

(2015) Silvia Fabiani et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

A gene-based association method for mapping traits using reference transcriptome data

(2015) Eric R Gamazon et al.   NATURE GENETICS

Effect of parasitic infection on dopamine biosynthesis in dopaminergic cells

(2015) H.L. Martin et al.   NEUROSCIENCE

Cancer Stem Cells: The Promise and the Potential

(2015) Jaffer A. Ajani et al.   SEMINARS IN ONCOLOGY

Toxoplasma gondii Infections Alter GABAergic Synapses and Signaling in the Central Nervous System

(2015) Justin M. Brooks et al.   mBio

Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate

(2015) Priya Srikanth et al.   Cell Reports

Toxoplasmosis and Epilepsy — Systematic Review and Meta Analysis

(2015) Edgard B. Ngoungou et al.   PLoS Neglected Tropical Diseases

Mechanisms of Host Behavioral Change in Toxoplasma gondii Rodent Association

(2015) Ajai Vyas   PLoS Pathogens

Oxytocin and vasopressin: linking pituitary neuropeptides and their receptors to social neurocircuits

(2015) Danielle A. Baribeau et al.   Frontiers in Neuroscience

Role of neuroinflammation in the emotional and cognitive alterations displayed by animal models of obesity

(2015) Nathalie Castanon et al.   Frontiers in Neuroscience

AttenuatedToxoplasma gondiitherapy of disseminated pancreatic cancer generates long-lasting immunity to pancreatic cancer

(2015) Kiah L. Sanders et al.   OncoImmunology

The eEF1A Proteins: At the Crossroads of Oncogenesis, Apoptosis, and Viral Infections

(2015) Wasim Abbas et al.   Frontiers in Oncology

Possible Link Between Toxoplasma Gondii and the Anosmia Associated With Neurodegenerative Diseases

(2014) Joseph Prandota   American Journal of Alzheimers Disease and Other Dementias

Establishing Genomic/Transcriptomic Links Between Alzheimer’s Disease and Type 2 Diabetes Mellitus by Meta-Analysis Approach

(2014) Zeenat Mirza et al.   CNS & Neurological Disorders-Drug Targets

USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin

(2014) T. M. Durcan et al.   EMBO JOURNAL

Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control

(2014) Gian-Luca McLelland et al.   EMBO JOURNAL

Infection by Toxoplasma gondii Specifically Induces Host c-Myc and the Genes This Pivotal Transcription Factor Regulates

(2014) Magdalena Franco et al.   EUKARYOTIC CELL

ALOX12in Human Toxoplasmosis

(2014) William H. Witola et al.   INFECTION AND IMMUNITY

Toxoplasma gondiiVirulence Factor ROP18 Inhibits the Host NF-κB Pathway by Promoting p65 Degradation

(2014) Jian Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immune Profiling of Pregnant Toxoplasma-Infected US and Colombia Patients Reveals Surprising Impacts of Infection on Peripheral Blood Cytokines

(2014) Lena Pernas et al.   JOURNAL OF INFECTIOUS DISEASES

Prevention of chronic disease in the 21st century: elimination of the leading preventable causes of premature death and disability in the USA

(2014) Ursula E Bauer et al.   LANCET

Digesting the emerging role for the gut microbiome in central nervous system demyelination

(2014) Jennifer Joscelyn et al.   Multiple Sclerosis Journal

Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7

(2014) Jennifer Y Tan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data

(2014) Shihao Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of extracellular vesicles in the progression of neurodegenerative disease and cancer

(2014) Kate M. Candelario et al.   TRENDS IN MOLECULAR MEDICINE

Effectiveness of a novel immunogenic nanoparticle platform for Toxoplasma peptide vaccine in HLA transgenic mice

(2014) Kamal El Bissati et al.   VACCINE

Experimental Studies in Epilepsy: Immunologic and Inflammatory Mechanisms

(2014) Agustín Legido et al.   Seminars in Pediatric Neurology

Dual Role for Inflammasome Sensors NLRP1 and NLRP3 in Murine Resistance to Toxoplasma gondii

(2014) G. Gorfu et al.   mBio

A Highly Conserved Toxo1 Haplotype Directs Resistance to Toxoplasmosis and Its Associated Caspase-1 Dependent Killing of Parasite and Host Macrophage

(2014) Pierre Cavailles et al.   PLoS Pathogens

Inflammasome Sensor NLRP1 Controls Rat Macrophage Susceptibility to Toxoplasma gondii

(2014) Kimberly M. Cirelli et al.   PLoS Pathogens

From Pathways to Targets: Understanding the Mechanisms behind Polyglutamine Disease

(2014) Jonasz Jeremiasz Weber et al.   Biomed Research International

Systems Approach to Neurodegenerative Disease Biomarker Discovery

(2013) Christopher Lausted et al.   Annual Review of Pharmacology and Toxicology

The role of microbiome in central nervous system disorders

(2013) Yan Wang et al.   BRAIN BEHAVIOR AND IMMUNITY

Avirulent Toxoplasma gondii Generates Therapeutic Antitumor Immunity by Reversing Immunosuppression in the Ovarian Cancer Microenvironment

(2013) Jason R. Baird et al.   CANCER RESEARCH

The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance

(2013) Florian A. Siebzehnrubl et al.   EMBO Molecular Medicine

NLRP1 Is an Inflammasome Sensor for Toxoplasma gondii

(2013) Sarah E. Ewald et al.   INFECTION AND IMMUNITY

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Symptoms of depression and anxiety in anorexia nervosa: Links with plasma tryptophan and serotonin metabolism.

(2013) Claire Gauthier et al.   PSYCHONEUROENDOCRINOLOGY

Human Pluripotent Stem Cell Differentiation into Authentic Striatal Projection Neurons

(2013) Alessia Delli Carri et al.   Stem Cell Reviews and Reports

Pten Loss in Olig2 Expressing Neural Progenitor Cells and Oligodendrocytes Leads to Interneuron Dysplasia and Leukodystrophy

(2013) Cécile L. Maire et al.   STEM CELLS

Human Innate Immunity to Toxoplasma gondii Is Mediated by Host Caspase-1 and ASC and Parasite GRA15

(2013) L. Gov et al.   mBio

Transcriptional Analysis of Murine Macrophages Infected with Different Toxoplasma Strains Identifies Novel Regulation of Host Signaling Pathways

(2013) Mariane B. Melo et al.   PLoS Pathogens

Toxoplasma gondii-Induced Activation of EGFR Prevents Autophagy Protein-Mediated Killing of the Parasite

(2013) Luis Muniz-Feliciano et al.   PLoS Pathogens

Possible role of Toxoplasma gondii in brain cancer through modulation of host microRNAs

(2013) Sivasakthivel Thirugnanam et al.   Infectious Agents and Cancer

Neurogenic potential of progenitor cells isolated from postmortem human Parkinsonian brains

(2012) Shanshan Wang et al.   BRAIN RESEARCH

The MicroRNA-17-92 Family of MicroRNA Clusters in Development and Disease

(2012) Carla P. Concepcion et al.   CANCER JOURNAL

Prematurity and Severity Are Associated With Toxoplasma gondii Alleles (NCCCTS, 1981–2009)

(2012) Rima McLeod et al.   CLINICAL INFECTIOUS DISEASES

NK Cell-Derived Interferon-γ Orchestrates Cellular Dynamics and the Differentiation of Monocytes into Dendritic Cells at the Site of Infection

(2012) Romina S. Goldszmid et al.   IMMUNITY

Impaired Innate Immunity in Mice Deficient in Interleukin-1 Receptor-Associated Kinase 4 Leads to Defective Type 1 T Cell Responses, B Cell Expansion, and Enhanced Susceptibility to Infection with Toxoplasma gondii

(2012) Samantha R. Béla et al.   INFECTION AND IMMUNITY

Brain cancer mortality rates increase with Toxoplasma gondii seroprevalence in France

(2012) Marion Vittecoq et al.   INFECTION GENETICS AND EVOLUTION

Immune-Mediated Regression of Established B16F10 Melanoma by Intratumoral Injection of Attenuated Toxoplasma gondii Protects against Rechallenge

(2012) J. R. Baird et al.   JOURNAL OF IMMUNOLOGY

Association of a NOD2 Gene Polymorphism and T-Helper 17 Cells With Presumed Ocular Toxoplasmosis

(2012) M. S. Dutra et al.   JOURNAL OF INFECTIOUS DISEASES

Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells

(2012) Tajie H. Harris et al.   NATURE

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MiR-218 sensitizes glioma cells to apoptosis and inhibits tumorigenicity by regulating ECOP-mediated suppression of NF-κB activity

(2012) Hongping Xia et al.   NEURO-ONCOLOGY

Immunological regulation of neurogenic niches in the adult brain

(2012) O. Gonzalez-Perez et al.   NEUROSCIENCE

STRING v9.1: protein-protein interaction networks, with increased coverage and integration

(2012) Andrea Franceschini et al.   NUCLEIC ACIDS RESEARCH

Toxoplasma gondii Infection in the Brain Inhibits Neuronal Degeneration and Learning and Memory Impairments in a Murine Model of Alzheimer's Disease

(2012) Bong-Kwang Jung et al.   PLoS One

Ataxin-2-Like Is a Regulator of Stress Granules and Processing Bodies

(2012) Christian Kaehler et al.   PLoS One

Toxoplasma gondii and Other Risk Factors for Schizophrenia: An Update

(2012) E. F. Torrey et al.   SCHIZOPHRENIA BULLETIN

Chitinase Dependent Control of Protozoan Cyst Burden in the Brain

(2012) J. Philip Nance et al.   PLoS Pathogens

Toxoplasma gondii Dense Granule Antigen 1 stimulates apoptosis of monocytes through autocrine TGF-β signaling

(2011) Anna D’Angelillo et al.   APOPTOSIS

Incidence of adult brain cancers is higher in countries where the protozoan parasite Toxoplasma gondii is common

(2011) F. Thomas et al.   Biology Letters

Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats

(2011) Lana J Mawhinney et al.   BMC NEUROSCIENCE

Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner

(2011) Janel E. Le Belle et al.   Cell Stem Cell

Unrecognized Ingestion of Toxoplasma gondii Oocysts Leads to Congenital Toxoplasmosis and Causes Epidemics in North America

(2011) K. Boyer et al.   CLINICAL INFECTIOUS DISEASES

Temporally controlled modulation of FGF/ERK signaling directs midbrain dopaminergic neural progenitor fate in mouse and human pluripotent stem cells

(2011) I. Jaeger et al.   DEVELOPMENT

Evaluation of protein loading techniques and improved separation in OFFGEL isoelectric focusing

(2011) Eva-Maria Keidel et al.   ELECTROPHORESIS

Converging miRNA functions in diverse brain disorders: A case for miR-124 and miR-126

(2011) Kai C. Sonntag et al.   EXPERIMENTAL NEUROLOGY

The origins of glioma: E Pluribus Unum?

(2011) F. A. Siebzehnrubl et al.   GLIA

Toxoplasma gondii HLA-B*0702-restricted GRA720-28 peptide with adjuvants and a universal helper T cell epitope elicits CD8+ T cells producing interferon-γ and reduces parasite burden in HLA-B*0702 mice

(2011) Hua Cong et al.   HUMAN IMMUNOLOGY

Toxoplasma gondii Induces B7-2 Expression through Activation of JNK Signal Transduction

(2011) Pedro Morgado et al.   INFECTION AND IMMUNITY

Plasma Clusterin and the Risk of Alzheimer Disease

(2011) Elisabeth M. C. Schrijvers   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

ATF6β is a host cellular target of theToxoplasma gondiivirulence factor ROP18

(2011) Masahiro Yamamoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Strain-specific activation of the NF-κB pathway by GRA15, a novelToxoplasma gondiidense granule protein

(2011) Emily E. Rosowski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Oral oocyst-induced mouse model of toxoplasmosis: effect of infection with Toxoplasma gondii strains of different genotypes, dose, and mouse strains (transgenic, out-bred, in-bred) on pathogenesis and mortality

(2011) J. P. DUBEY et al.   PARASITOLOGY

The Neurotropic Parasite Toxoplasma Gondii Increases Dopamine Metabolism

(2011) Emese Prandovszky et al.   PLoS One

Fatal Attraction Phenomenon in Humans – Cat Odour Attractiveness Increased for Toxoplasma-Infected Men While Decreased for Infected Women

(2011) Jaroslav Flegr et al.   PLoS Neglected Tropical Diseases

Exposure to Prenatal Infection and Risk of Schizophrenia

(2011) Alan S. Brown   Frontiers in Psychiatry

Patterns of microRNA expression in normal and early Alzheimer’s disease human temporal cortex: white matter versus gray matter

(2010) Wang-Xia Wang et al.   ACTA NEUROPATHOLOGICA

Could Toxoplasma gondii Have any Role in Alzheimer Disease?

(2010) Ozge Yilmaz Kusbeci et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Evidence for associations between the purinergic receptor P2X7 (P2RX7) and toxoplasmosis

(2010) S E Jamieson et al.   GENES AND IMMUNITY

NALP1 Influences Susceptibility to Human Congenital Toxoplasmosis, Proinflammatory Cytokine Response, and Fate ofToxoplasma gondii-Infected Monocytic Cells

(2010) William H. Witola et al.   INFECTION AND IMMUNITY

ToxoplasmaRhoptry Protein 16 (ROP16) Subverts Host Function by Direct Tyrosine Phosphorylation of STAT6

(2010) Yi-Ching Ong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P2X7 Receptor-Mediated Killing of an Intracellular Parasite, Toxoplasma gondii, by Human and Murine Macrophages

(2010) M. P. Lees et al.   JOURNAL OF IMMUNOLOGY

Sub-proteomic fractionation, iTRAQ, and OFFGEL-LC–MS/MS approaches to cardiac proteomics

(2010) Chad M. Warren et al.   Journal of Proteomics

Candidate gene analysis of ocular toxoplasmosis in Brazil: evidence for a role for toll-like receptor 9 (TLR9)

(2010) Alba L Peixoto-Rangel et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Host genetic and epigenetic factors in toxoplasmosis

(2010) Sarra E Jamieson et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

(2010) Dimitrios Iliopoulos et al.   MOLECULAR CELL

Have Tumor Suppressor PDCD4 and its Counteragent Oncogenic miR-21 Gone Rogue?

(2010) M. R. Young et al.   MOLECULAR INTERVENTIONS

MicroRNAs modulate the noncanonical transcription factor NF-κB pathway by regulating expression of the kinase IKKα during macrophage differentiation

(2010) Tao Li et al.   NATURE IMMUNOLOGY

Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neurone navigator 3

(2010) M. Shioya et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Toxoplasma gondii Infection Specifically Increases the Levels of Key Host MicroRNAs

(2010) Gusti M. Zeiner et al.   PLoS One

microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus

(2010) S. T. Magill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of T. gondii epitopes, adjuvants, and host genetic factors that influence protection of mice and humans

(2010) Tze Guan Tan et al.   VACCINE

Towards an immunosense vaccine to prevent toxoplasmosis: Protective Toxoplasma gondii epitopes restricted by HLA-A*0201

(2010) Hua Cong et al.   VACCINE

Evidence for the involvement of genetic variation in the oxytocin receptor gene (OXTR ) in the etiology of autistic disorders on high-functioning level

(2009) Anne-Kathrin Wermter et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

FoxOs Cooperatively Regulate Diverse Pathways Governing Neural Stem Cell Homeostasis

(2009) Ji-hye Paik et al.   Cell Stem Cell

MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells

(2009) Pedro M. Borralho et al.   FEBS Journal

Up-regulated microRNA-143 transcribed by nuclear factor kappa B enhances hepatocarcinoma metastasis by repressing fibronectin expression

(2009) Xiaoying Zhang et al.   HEPATOLOGY

Fragile histidine triad protein: structure, function, and its association with tumorogenesis

(2009) Md. Imtaiyaz Hassan et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Adaptive suppression of the ATF4–CHOP branch of the unfolded protein response by toll-like receptor signalling

(2009) Connie W. Woo et al.   NATURE CELL BIOLOGY

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

(2009) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

Granulocyte colony stimulating factor decreases brain amyloid burden and reverses cognitive impairment in Alzheimer's mice

(2009) J. Sanchez-Ramos et al.   NEUROSCIENCE

Common astrocytic programs during brain development, injury and cancer

(2009) Daniel J. Silver et al.   TRENDS IN NEUROSCIENCES

Toxoplasmosis-Associated Neovascular Lesions Treated Successfully With Ranibizumab and Antiparasitic Therapy

(2008) Joseph D. Benevento   ARCHIVES OF OPHTHALMOLOGY

Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity

(2008) Daniel B. Stetson et al.   CELL

Angelman Syndrome Due to a Novel Splicing Mutation of the UBE3A Gene

(2008) Stefano Sartori et al.   JOURNAL OF CHILD NEUROLOGY

Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasitic infection

(2008) Gretchen Hermes et al.   Journal of Neuroinflammation

Platelet-derived growth factor-α receptor activation is required for human cytomegalovirus infection

(2008) Liliana Soroceanu et al.   NATURE

Regulation of IKKβ by miR-199a affects NF-κB activity in ovarian cancer cells

(2008) R Chen et al.   ONCOGENE

Genetic and Epigenetic Factors at COL2A1 and ABCA4 Influence Clinical Outcome in Congenital Toxoplasmosis

(2008) Sarra E. Jamieson et al.   PLoS One

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/ -secretase expression

(2008) S. S. Hebert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A microRNA-based gene dysregulation pathway in Huntington's disease

(2007) Rory Johnson et al.   NEUROBIOLOGY OF DISEASE