Location of the CD8 T Cell Epitope within the Antigenic Precursor Determines Immunogenicity and Protection against the Toxoplasma gondii Parasite

Infection with Trypanosoma cruzi Restricts the Repertoire of Parasite-Specific CD8+ T Cells Leading to Immunodominance

(2014) F. Tzelepis et al.   JOURNAL OF IMMUNOLOGY

Naive Precursor Frequencies and MHC Binding Rather Than the Degree of Epitope Diversity Shape CD8+ T Cell Immunodominance

(2014) M. F. Kotturi et al.   JOURNAL OF IMMUNOLOGY

Positional Bias of MHC Class I Restricted T-Cell Epitopes in Viral Antigens Is Likely due to a Bias in Conservation

(2013) Yohan Kim et al.   PLoS Computational Biology

The Toxoplasma gondii Peptide AS15 Elicits CD4 T Cells That Can Control Parasite Burden

(2012) Harshita Satija Grover et al.   INFECTION AND IMMUNITY

The Role of Naive T Cell Precursor Frequency and Recruitment in Dictating Immune Response Magnitude

(2012) M. K. Jenkins et al.   JOURNAL OF IMMUNOLOGY

A Novel Benzodioxole-Containing Inhibitor of Toxoplasma gondii Growth Alters the Parasite Cell Cycle

(2011) Edwin Kamau et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Sec22b Regulates Phagosomal Maturation and Antigen Crosspresentation by Dendritic Cells

(2011) Ignacio Cebrian et al.   CELL

Providing ligands for MHC class I molecules

(2011) Peter van Endert   CELLULAR AND MOLECULAR LIFE SCIENCES

Translating DRiPs: progress in understanding viral and cellular sources of MHC class I peptide ligands

(2011) Brian P. Dolan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Extensive Polymorphism and Evidence of Immune Selection in a Highly Dominant Antigen Recognized by Bovine CD8 T Cells Specific for Theileria annulata

(2011) Niall D. MacHugh et al.   INFECTION AND IMMUNITY

Strain-specific activation of the NF-κB pathway by GRA15, a novelToxoplasma gondiidense granule protein

(2011) Emily E. Rosowski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Precursor Frequency and Competition Dictate the HLA-A2-Restricted CD8+ T Cell Responses to Influenza A Infection and Vaccination in HLA-A2.1 Transgenic Mice

(2011) A. C. L. Tan et al.   JOURNAL OF IMMUNOLOGY

Defining the Herpes Simplex Virus-Specific CD8 + T Cell Repertoire in C57BL/6 Mice

(2011) Anthony J. St. Leger et al.   JOURNAL OF IMMUNOLOGY

Cross-presentation of peptides from intracellular pathogens by MHC class I molecules

(2010) Nicolas Blanchard et al.   Annals of the New York Academy of Sciences

Phosphorylation of Immunity-Related GTPases by a Toxoplasma gondii-Secreted Kinase Promotes Macrophage Survival and Virulence

(2010) Sarah J. Fentress et al.   Cell Host & Microbe

Post-translational membrane sorting of the Toxoplasma gondii GRA6 protein into the parasite-containing vacuole is driven by its N-terminal domain

(2010) Claire Gendrin et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion

(2010) Nicole L. La Gruta et al.   JOURNAL OF CLINICAL INVESTIGATION

Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing Defines the Composition and Structure of MHC Class I Peptide Repertoire in Normal and Virus-Infected Cells

(2010) N. Blanchard et al.   JOURNAL OF IMMUNOLOGY

Topological journey of parasite-derived antigens for presentation by MHC class I molecules

(2010) Nicolas Blanchard et al.   TRENDS IN IMMUNOLOGY

Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondii

(2010) Tobias Steinfeldt et al.   PLOS BIOLOGY

Differential Regulation of Effector- and Central-Memory Responses to Toxoplasma gondii Infection by IL-12 Revealed by Tracking of Tgd057-Specific CD8+ T Cells

(2010) Douglas C. Wilson et al.   PLoS Pathogens

Selection of Polymorphic Peptides from GRA6 and GRA7 Sequences of Toxoplasma gondii Strains To Be Used in Serotyping

(2009) S. Sousa et al.   Clinical and Vaccine Immunology

Host ER–parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation inToxoplasma gondii–infected dendritic cells

(2009) Romina S. Goldszmid et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Amino Acid Sequences Flanking an Antigenic Determinant Can Strongly Affect MHC Class I Cross-Presentation without Altering Direct Presentation

(2009) X. Ma et al.   JOURNAL OF IMMUNOLOGY

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

(2009) Stefan Tenzer et al.   NATURE IMMUNOLOGY

Dynamic Imaging of CD8+ T Cells and Dendritic Cells during Infection with Toxoplasma gondii

(2009) Beena John et al.   PLoS Pathogens

Endogenous Naive CD8+ T Cell Precursor Frequency Regulates Primary and Memory Responses to Infection

(2008) Joshua J. Obar et al.   IMMUNITY

Parasite Stage–Specific Recognition of EndogenousToxoplasma gondii–Derived CD8+T Cell Epitopes

(2008) Eva‐Maria Frickel et al.   JOURNAL OF INFECTIOUS DISEASES

Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum

(2008) Nicolas Blanchard et al.   NATURE IMMUNOLOGY