Klotho Is Neuroprotective in the Superoxide Dismutase (SOD1G93A) Mouse Model of ALS
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Title
Klotho Is Neuroprotective in the Superoxide Dismutase (SOD1G93A) Mouse Model of ALS
Authors
Keywords
Amyotrophic lateral sclerosis, Neurodegeneration, Microglia, Neuroinflammation, Motor neurons, Therapeutics
Journal
JOURNAL OF MOLECULAR NEUROSCIENCE
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-06-27
DOI
10.1007/s12031-019-01356-2
References
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Note: Only part of the references are listed.- Klotho protects the heart from hyperglycemia-induced injury by inactivating ROS and NF-κB-mediated inflammation both in vitro and in vivo
- (2018) Yue Guo et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Activation of the Anti-Aging and Cognition-Enhancing Gene Klotho by CRISPR-dCas9 Transcriptional Effector Complex
- (2018) Ci-Di Chen et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Lentivirus-mediated klotho up-regulation improves aging-related memory deficits and oxidative stress in senescence-accelerated mouse prone-8 mice
- (2018) Hong-Jing Zhou et al. LIFE SCIENCES
- MIF inhibits the formation and toxicity of misfolded SOD1 amyloid aggregates: implications for familial ALS
- (2018) Neta Shvil et al. Cell Death & Disease
- Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of RIG-I/NF-κB Signaling
- (2018) Hong-Jing Zhou et al. Frontiers in Pharmacology
- Aging and sex affect soluble alpha klotho levels in bonobos and chimpanzees
- (2018) V. Behringer et al. Frontiers in Zoology
- Klotho controls the brain–immune system interface in the choroid plexus
- (2018) Lei Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The anti-aging protein klotho alleviates injury of nigrostriatal dopaminergic pathway in 6-hydroxydopamine rat model of Parkinson's disease: Involvement of PKA/CaMKII/CREB signaling
- (2017) Tourandokht Baluchnejadmojarad et al. EXPERIMENTAL GERONTOLOGY
- Secreted αKlotho isoform protects against age-dependent memory deficits
- (2017) A Massó et al. MOLECULAR PSYCHIATRY
- Motor Neuron Gene Therapy: Lessons from Spinal Muscular Atrophy for Amyotrophic Lateral Sclerosis
- (2017) Andrew P. Tosolini et al. Frontiers in Molecular Neuroscience
- Spinal cord homogenates from SOD1 familial amyotrophic lateral sclerosis induce SOD1 aggregation in living cells
- (2017) Edward Pokrishevsky et al. PLoS One
- Klotho Inhibits Interleukin-8 Secretion from Cystic Fibrosis Airway Epithelia
- (2017) Stefanie Krick et al. Scientific Reports
- Protein folding alterations in amyotrophic lateral sclerosis
- (2016) Sonam Parakh et al. BRAIN RESEARCH
- Overexpression of β-Klotho in Adipose Tissue Sensitizes Male Mice to Endogenous FGF21 and Provides Protection From Diet-Induced Obesity
- (2016) Ricardo J. Samms et al. ENDOCRINOLOGY
- Reduction of cytosolic phospholipase A2α upregulation delays the onset of symptoms in SOD1G93A mouse model of amyotrophic lateral sclerosis
- (2016) Yulia Solomonov et al. Journal of Neuroinflammation
- Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS
- (2016) Daniel Cacabelos et al. Acta Neuropathologica Communications
- Microglial neuroinflammation contributes to tau accumulation in chronic traumatic encephalopathy
- (2016) Jonathan D. Cherry et al. Acta Neuropathologica Communications
- Astrocytes and Microglia as Non-cell Autonomous Players in the Pathogenesis of ALS
- (2016) Junghee Lee et al. Experimental Neurobiology
- Emerging mechanisms of molecular pathology in ALS
- (2015) Owen M. Peters et al. JOURNAL OF CLINICAL INVESTIGATION
- The Anti-Aging Protein Klotho Enhances Remyelination Following Cuprizone-Induced Demyelination
- (2015) Ella Zeldich et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Life Extension Factor Klotho Prevents Mortality and Enhances Cognition in hAPP Transgenic Mice
- (2015) D. B. Dubal et al. JOURNAL OF NEUROSCIENCE
- Klotho Protects Dopaminergic Neuron Oxidant-Induced Degeneration by Modulating ASK1 and p38 MAPK Signaling Pathways
- (2015) Reynolds K. Brobey et al. PLoS One
- Tet1-mediated DNA demethylation regulates neuronal cell death induced by oxidative stress
- (2015) Yong-Juan Xin et al. Scientific Reports
- A Quick Phenotypic Neurological Scoring System for Evaluating Disease Progression in the SOD1-G93A Mouse Model of ALS
- (2015) Theo Hatzipetros et al. Jove-Journal of Visualized Experiments
- Modulation of SOD1 Subcellular Localization by Transfection with Wild- or Mutant-type SOD1 in Primary Neuron and Astrocyte Cultures from ALS Mice
- (2015) Do-Yeon Lee et al. Experimental Neurobiology
- Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice
- (2014) Oleg Butovsky et al. ANNALS OF NEUROLOGY
- The Neuroprotective Effect of Klotho is Mediated via Regulation of Members of the Redox System
- (2014) Ella Zeldich et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Microglia and motor neurons during disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis: changes in arginase1 and inducible nitric oxide synthase
- (2014) Katherine E Lewis et al. Journal of Neuroinflammation
- Microglia change from a reactive to an age-like phenotype with the time in culture
- (2014) Cláudia Caldeira et al. Frontiers in Cellular Neuroscience
- Diagnostic timelines and delays in diagnosing amyotrophic lateral sclerosis (ALS)
- (2014) Sabrina Paganoni et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis
- (2013) Thomas Philips et al. BRAIN
- Soluble serum Klotho levels in healthy subjects. Comparison of two different immunoassays
- (2013) Lise Pedersen et al. CLINICAL BIOCHEMISTRY
- The Antiaging Protein Klotho Enhances Oligodendrocyte Maturation and Myelination of the CNS
- (2013) C.-D. Chen et al. JOURNAL OF NEUROSCIENCE
- Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis
- (2013) Shin H Kang et al. NATURE NEUROSCIENCE
- Count-based differential expression analysis of RNA sequencing data using R and Bioconductor
- (2013) Simon Anders et al. Nature Protocols
- Wnt Signaling is Altered by Spinal Cord Neuronal Dysfunction in Amyotrophic Lateral Sclerosis Transgenic Mice
- (2013) Li Yu et al. NEUROCHEMICAL RESEARCH
- Neuronal Death in Amyotrophic Lateral Sclerosis (ALS): What Can We Learn from Genetics?
- (2012) J. Sreedharan CNS & Neurological Disorders-Drug Targets
- Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS
- (2012) Bing Liao et al. EXPERIMENTAL NEUROLOGY
- Small-molecule Klotho enhancers as novel treatment of neurodegeneration
- (2012) Carmela R Abraham et al. Future Medicinal Chemistry
- Effect of Sex on Lifespan, Disease Progression, and the Response to Methionine Sulfoximine in the SOD1 G93A Mouse Model for ALS
- (2012) Monica Bame et al. Gender Medicine
- The role of Klotho in energy metabolism
- (2012) M. Shawkat Razzaque Nature Reviews Endocrinology
- Wnt signaling pathway is involved in the pathogenesis of amyotrophic lateral sclerosis in adult transgenic mice
- (2012) Yanchun Chen et al. NEUROLOGICAL RESEARCH
- Identification of novel small molecules that elevate Klotho expression
- (2011) Gwendalyn D. King et al. BIOCHEMICAL JOURNAL
- Klotho Inhibits Transforming Growth Factor-β1 (TGF-β1) Signaling and Suppresses Renal Fibrosis and Cancer Metastasis in Mice
- (2011) Shigehiro Doi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Plasma Klotho and Cardiovascular Disease in Adults
- (2011) Richard D. Semba et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- Astroglial Inhibition of NF-κB Does Not Ameliorate Disease Onset and Progression in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS)
- (2011) Claudia Crosio et al. PLoS One
- Metformin Treatment Has No Beneficial Effect in a Dose-Response Survival Study in the SOD1G93A Mouse Model of ALS and Is Harmful in Female Mice
- (2011) Hannah M. Kaneb et al. PLoS One
- Neuroinflammation modulates distinct regional and temporal clinical responses in ALS mice
- (2010) David R. Beers et al. BRAIN BEHAVIOR AND IMMUNITY
- Effects of gender in amyotrophic lateral sclerosis
- (2010) Pamela A. McCombe et al. Gender Medicine
- WNT signaling in activated microglia is proinflammatory
- (2010) Carina Halleskog et al. GLIA
- Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS
- (2010) Daryl A Bosco et al. NATURE NEUROSCIENCE
- Klotho and aging
- (2009) Makoto Kuro-o BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- No Benefit from Chronic Lithium Dosing in a Sibling-Matched, Gender Balanced, Investigator-Blinded Trial Using a Standard Mouse Model of Familial ALS
- (2009) Alan Gill et al. PLoS One
- Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis
- (2008) Koji Yamanaka et al. NATURE NEUROSCIENCE
- Morphological and biochemical signs of age-related neurodegenerative changes in klotho mutant mice
- (2008) M. Shiozaki et al. NEUROSCIENCE
- Gene profile analysis implicates Klotho as an important contributor to aging changes in brain white matter of the rhesus monkey
- (2007) James A. Duce et al. GLIA
- Effects of estrogen on lifespan and motor functions in female hSOD1 G93A transgenic mice
- (2007) Chan-Il Choi et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
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