Reduction of cytosolic phospholipase A2α upregulation delays the onset of symptoms in SOD1G93A mouse model of amyotrophic lateral sclerosis

Multifactorial Gene Therapy Enhancing the Glutamate Uptake System and Reducing Oxidative Stress Delays Symptom Onset and Prolongs Survival in the SOD1-G93A ALS Mouse Model

(2015) Chen Benkler et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The role of cytosolic phospholipase A2α in amyloid precursor protein induction by amyloid beta1-42: implication for neurodegeneration

(2015) Chen Sagy-Bross et al.   JOURNAL OF NEUROCHEMISTRY

Immunization with a Myelin-Derived Antigen Activates the Brain's Choroid Plexus for Recruitment of Immunoregulatory Cells to the CNS and Attenuates Disease Progression in a Mouse Model of ALS

(2015) G. Kunis et al.   JOURNAL OF NEUROSCIENCE

Albumin induces excitatory synaptogenesis through astrocytic TGF-β/ALK5 signaling in a model of acquired epilepsy following blood–brain barrier dysfunction

(2015) Itai Weissberg et al.   NEUROBIOLOGY OF DISEASE

Accelerated microglial pathology is associated with Aβ plaques in mouse models of Alzheimer's disease

(2014) Rona Baron et al.   AGING CELL

Cytosolic phospholipase A2protein as a novel therapeutic target for spinal cord injury

(2014) Nai-Kui Liu et al.   ANNALS OF NEUROLOGY

Microglia Induce Motor Neuron Death via the Classical NF-κB Pathway in Amyotrophic Lateral Sclerosis

(2014) Ashley E. Frakes et al.   NEURON

Cytosolic phospholipase A2α upregulation mediates apoptotic neuronal death induced by aggregated amyloid-β peptide1–42

(2013) Chen Sagy-Bross et al.   NEUROCHEMISTRY INTERNATIONAL

A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model

(2013) Isaac M. Chiu et al.   Cell Reports

cPLA2α knockout mice exhibit abnormalities in the architecture and synapses of cortical neurons

(2012) Bao-Xi Qu et al.   BRAIN RESEARCH

Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS

(2012) Oleg Butovsky et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular pathology and genetic advances in amyotrophic lateral sclerosis: an emerging molecular pathway and the significance of glial pathology

(2011) Paul G. Ince et al.   ACTA NEUROPATHOLOGICA

Arachidonyl trifluoromethyl ketone ameliorates experimental autoimmune encephalomyelitis via blocking peroxynitrite formation in mouse spinal cord white matter

(2011) Adam C. Vana et al.   EXPERIMENTAL NEUROLOGY

Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease

(2011) Thomas Philips et al.   LANCET NEUROLOGY

Increased expression and activation of cytosolic phospholipase A2 in the spinal cord of patients with sporadic amyotrophic lateral sclerosis

(2010) Noriyuki Shibata et al.   ACTA NEUROPATHOLOGICA

Inhibition of cPLA2 activation by Ginkgo biloba extract protects spinal cord neurons from glutamate excitotoxicity and oxidative stress-induced cell death

(2010) Zhen Zhao et al.   JOURNAL OF NEUROCHEMISTRY

Regulatory role of cytosolic phospholipase A2α in NADPH oxidase activity and in inducible nitric oxide synthase induction by aggregated Aβ1-42in microglia

(2009) I. Szaingurten-Solodkin et al.   GLIA

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice

(2009) I. M. Chiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduction of cPLA2αoverexpression: An efficient anti-inflammatory therapy for collagen-induced arthritis

(2008) Lior Raichel et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice

(2008) K. Yamanaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS

(2008) I. M. Chiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA