Identification of novel small molecules that elevate Klotho expression

Klotho inhibits growth and promotes apoptosis in human lung cancer cell line A549

(2010) Bo Chen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Parathyroid resistance to FGF23 in kidney transplant recipients: back to the past or ahead to the future?

(2010) Hirotaka Komaba et al.   KIDNEY INTERNATIONAL

Parathyroid Klotho and FGF-receptor 1 expression decline with renal function in hyperparathyroid patients with chronic kidney disease and kidney transplant recipients

(2010) Tijana Krajisnik et al.   KIDNEY INTERNATIONAL

The anti-aging gene KLOTHO is a novel target for epigenetic silencing in human cervical carcinoma

(2010) Jaehyouk Lee et al.   Molecular Cancer

KLOTHO Gene Polymorphisms G-395A and C1818T Are Associated with Low-Density Lipoprotein Cholesterol and Uric Acid in Japanese Hemodialysis Patients

(2009) Yasuhiko Shimoyama et al.   AMERICAN JOURNAL OF NEPHROLOGY

An Oral Sorbent, AST-120, Increases Klotho Expression and Inhibits Cell Senescence in the Kidney of Uremic Rats

(2009) Ayinuer Adijiang et al.   AMERICAN JOURNAL OF NEPHROLOGY

Klotho and aging

(2009) Makoto Kuro-o   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

A potential regulatory single nucleotide polymorphism in the promoter of the Klotho gene may be associated with essential hypertension in the Chinese Han population

(2009) Hu-Lin Wang et al.   CLINICA CHIMICA ACTA

Transcriptional activation of the human Klotho gene by epidermal growth factor in HEK293 cells; role of Egr-1

(2009) Byeong Hyeok Choi et al.   GENE

KLOTHO Gene Polymorphism Is Associated With Coronary Artery Stenosis but Not With Coronary Calcification in a Korean Population

(2009) Sang-Ho Jo et al.   International Heart Journal

Regulation of Renal Outer Medullary Potassium Channel and Renal K+ Excretion by Klotho

(2009) S.-K. Cha et al.   MOLECULAR PHARMACOLOGY

Functional variant of KLOTHO: a breast cancer risk modifier among BRCA1 mutation carriers of Ashkenazi origin

(2009) I Wolf et al.   ONCOGENE

Polymorphism in the promoter region of the klotho gene (G-395A) is associated with early dysfunction in vascular access in hemodialysis patients

(2009) Youngsu Kim et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Klotho Expression in Epithelial Ovarian Cancer and its Association with Insulin-Like Growth Factors and Disease Progression

(2008) Lingeng Lu et al.   CANCER INVESTIGATION

Type I Membrane Klotho Expression Is Decreased and Inversely Correlated to Serum Calcium in Primary Hyperparathyroidism

(2008) Peyman Björklund et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Association of KLOTHO gene polymorphisms with knee osteoarthritis in Greek population

(2008) Aspasia Tsezou et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Klotho: a tumor suppressor and a modulator of the IGF-1 and FGF pathways in human breast cancer

(2008) I Wolf et al.   ONCOGENE

Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1

(2008) S.-K. Cha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A translocation causing increased  -Klotho level results in hypophosphatemic rickets and hyperparathyroidism

(2008) C. A. Brownstein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene profile analysis implicates Klotho as an important contributor to aging changes in brain white matter of the rhesus monkey

(2007) James A. Duce et al.   GLIA

HMG-CoA reductase inhibition improves anti-aging klotho protein expression and arteriosclerosis in rats with chronic inhibition of nitric oxide synthesis

(2007) Noriko Kuwahara et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY