A Review of Macrophage MicroRNAs’ Role in Human Asthma

Profiling of healthy and asthmatic airway smooth muscle cells following IL-1β treatment: a novel role for CCL20 in chronic mucus hyper-secretion

(2018) Alen Faiz et al.   EUROPEAN RESPIRATORY JOURNAL

Mannose receptor modulates macrophage polarization and allergic inflammation through miR-511-3p

(2018) Yufeng Zhou et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

miR-155 Modulates Cockroach Allergen– and Oxidative Stress–Induced Cyclooxygenase-2 in Asthma

(2018) Lipeng Qiu et al.   JOURNAL OF IMMUNOLOGY

Genome-Wide Posttranscriptional Dysregulation by MicroRNAs in Human Asthma as Revealed by Frac-seq

(2018) Rocio T. Martinez-Nunez et al.   JOURNAL OF IMMUNOLOGY

Isolation and profiling of plasma microRNAs: Biomarkers for asthma and allergic rhinitis

(2018) Ronaldo P. Panganiban et al.   METHODS

Repolarization of Tumor-Associated Macrophages in a Genetically Engineered Nonsmall Cell Lung Cancer Model by Intraperitoneal Administration of Hyaluronic Acid-Based Nanoparticles Encapsulating MicroRNA-125b

(2018) Neha N. Parayath et al.   NANO LETTERS

Macrophage polarization and allergic asthma

(2018) Arjun Saradna et al.   Translational Research

MicroRNA‑let‑7e regulates the progression and development of allergic rhinitis by targeting suppressor of cytokine signaling 4 and activating Janus kinase 1/signal transducer and activator of transcription 3 pathway

(2018) Lihua Li et al.   Experimental and Therapeutic Medicine

MicroRNA-223 Suppresses the Canonical NF-κB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation

(2018) Wenqing Zhou et al.   Cell Reports

Transcriptional Regulation of Macrophages Polarization by MicroRNAs

(2018) Heng Li et al.   Frontiers in Immunology

Hsa-miR-99b/let-7e/miR-125a Cluster Regulates Pathogen Recognition Receptor-Stimulated Suppressive Antigen-Presenting Cells

(2018) Dagmar Hildebrand et al.   Frontiers in Immunology

Snail-overexpressing Cancer Cells Promote M2-Like Polarization of Tumor-Associated Macrophages by Delivering MiR-21-Abundant Exosomes

(2018) Chia-Hsin Hsieh et al.   NEOPLASIA

Cobomarsen, an oligonucleotide inhibitor of miR-155, co-ordinately regulates multiple survival pathways to reduce cellular proliferation and survival in cutaneous T-cell lymphoma

(2018) Anita G. Seto et al.   BRITISH JOURNAL OF HAEMATOLOGY

Exosome-carried microRNA-based signature as a cellular trigger for the evolution of chronic lymphocytic leukemia into Richter syndrome

(2018) Ancuta Jurj et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

MicroRNA-146a is induced by inflammatory stimuli in airway epithelial cells and augments the anti-inflammatory effects of glucocorticoids

(2018) Kristin A. Lambert et al.   PLoS One

Multi-Step Regulation of the TLR4 Pathway by the miR-125a~99b~let-7e Cluster

(2018) Graziella Curtale et al.   Frontiers in Immunology

Potential new targets for drug development in severe asthma

(2018) Linda Zhu et al.   World Allergy Organization Journal

Inhibition of MicroRNA-21 by an antagomir ameliorates allergic inflammation in a mouse model of asthma

(2017) Hwa Young Lee et al.   EXPERIMENTAL LUNG RESEARCH

U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics

(2017) Diane Lefaudeux et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Circulating and Exosome-Packaged Hepatitis C Single-Stranded RNA Induce Monocyte Differentiation via TLR7/8 to Polarized Macrophages and Fibrocytes

(2017) Banishree Saha et al.   JOURNAL OF IMMUNOLOGY

Akt Signaling Pathway in Macrophage Activation and M1/M2 Polarization

(2017) Eleni Vergadi et al.   JOURNAL OF IMMUNOLOGY

Altered miR-155 Expression in Allergic Asthmatic Airways

(2017) C. Malmhäll et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice

(2017) Viola Neudecker et al.   Science Translational Medicine

MicroRNA-34/449 targets IGFBP-3 and attenuates airway remodeling by suppressing Nur77-mediated autophagy

(2017) Huiming Yin et al.   Cell Death & Disease

Small interfering RNA directed against microRNA‑155 delivered by a lentiviral vector attenuates asthmatic features in a mouse model of allergic asthma

(2017) Huilong Chen et al.   Experimental and Therapeutic Medicine

ICAM-1 regulates macrophage polarization by suppressing MCP-1 expression via miR-124 upregulation

(2017) Wei Gu et al.   Oncotarget

MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBPβ regulate innate immune signaling, the polarization of macrophages and the trafficking of Mycobacterium tuberculosis to lysosomes during infection

(2017) Sanjaya Kumar Sahu et al.   PLoS Pathogens

MicroRNA: Dynamic Regulators of Macrophage Polarization and Plasticity

(2017) Jezrom Bokcaerin Self-Fordham et al.   Frontiers in Immunology

Alternative Macrophage Activation Is Increased in Asthma

(2016) Pierre-Olivier Girodet et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Characterization of asthma endotypes: implications for therapy

(2016) Jeffrey R. Stokes et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

miR-125b controls monocyte adaptation to inflammation through mitochondrial metabolism and dynamics

(2016) I. Duroux-Richard et al.   BLOOD

Transcription factor C/EBP-β induces tumor-suppressor phosphatase PHLPP2 through repression of the miR-17–92 cluster in differentiating AML cells

(2016) Y Yan et al.   CELL DEATH AND DIFFERENTIATION

Resolvin D2 decreases TLR4 expression to mediate resolution in human monocytes

(2016) Amanda Croasdell et al.   FASEB JOURNAL

Asthma inflammatory phenotypes show differential microRNA expression in sputum

(2016) Tania Maes et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Circulating microRNAs as biomarkers in patients with allergic rhinitis and asthma

(2016) Ronaldo P. Panganiban et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Control of the Inflammatory Macrophage Transcriptional Signature by miR-155

(2016) Kyle A. Jablonski et al.   PLoS One

MiRNA-Mediated Macrophage Polarization and its Potential Role in the Regulation of Inflammatory Response

(2016) Kobina Essandoh et al.   SHOCK

MicroRNA-146a expression inhibits the proliferation and promotes the apoptosis of bronchial smooth muscle cells in asthma by directly targeting the epidermal growth factor receptor

(2016) Yanxia Zhang et al.   Experimental and Therapeutic Medicine

Overexpression of microRNA-155 suppresses chemokine expression induced by Interleukin-13 in BEAS-2B human bronchial epithelial cells

(2016) Satoshi Matsukura et al.   ALLERGOLOGY INTERNATIONAL

miRNA let-7b modulates macrophage polarization and enhances tumor-associated macrophages to promote angiogenesis and mobility in prostate cancer

(2016) Zhigang Wang et al.   Scientific Reports

ncRNA-regulated immune response and its role in inflammatory lung diseases

(2015) Na Xie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cyclooxygenase-2 and MicroRNA-155 Expression Are Elevated in Asthmatic Airway Smooth Muscle Cells

(2015) Brian S. Comer et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Tumor suppressor miR-34a targets PD-L1 and functions as a potential immunotherapeutic target in acute myeloid leukemia

(2015) Xi Wang et al.   CELLULAR SIGNALLING

Estrogen and progesterone decrease let-7f microRNA expression and increase IL-23/IL-23 receptor signaling and IL-17A production in patients with severe asthma

(2015) Dawn C. Newcomb et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

MicroRNA-9 regulates steroid-resistant airway hyperresponsiveness by reducing protein phosphatase 2A activity

(2015) Jing Jing Li et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

MicroRNA Cargo of Extracellular Vesicles from Alcohol-exposed Monocytes Signals Naive Monocytes to Differentiate into M2 Macrophages

(2015) Banishree Saha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

microRNA-26a suppresses recruitment of macrophages by down-regulating macrophage colony-stimulating factor expression through the PI3K/Akt pathway in hepatocellular carcinoma

(2015) Zong-Tao Chai et al.   Journal of Hematology & Oncology

PDL1 Regulation by p53 via miR-34

(2015) Maria Angelica Cortez et al.   JNCI-Journal of the National Cancer Institute

LPS-preconditioned mesenchymal stromal cells modify macrophage polarization for resolution of chronic inflammation via exosome-shuttled let-7b

(2015) Dongdong Ti et al.   Journal of Translational Medicine

PDL1 Regulation by p53 via miR-34

(2015) Maria Angelica Cortez et al.   JNCI-Journal of the National Cancer Institute

Turning 21: Induction of miR-21 as a Key Switch in the Inflammatory Response

(2015) Frederick J. Sheedy   Frontiers in Immunology

Regulation of Macrophage, Dendritic Cell, and Microglial Phenotype and Function by the SOCS Proteins

(2015) Sarah M. McCormick et al.   Frontiers in Immunology

miR-34 and p53: New Insights into a Complex Functional Relationship

(2015) Francisco Navarro et al.   PLoS One

Increased Protease-Activated Receptor-2 (PAR-2) Expression on CD14++CD16+ Peripheral Blood Monocytes of Patients with Severe Asthma

(2015) Nami Shrestha Palikhe et al.   PLoS One

MicroRNA Expression Is Altered in an Ovalbumin-Induced Asthma Model and Targeting miR-155 with Antagomirs Reveals Cellular Specificity

(2015) Maximilian W. Plank et al.   PLoS One

The role of macrophage IL-10/innate IFN interplay during virus-induced asthma

(2015) Mihnea T. Zdrenghea et al.   REVIEWS IN MEDICAL VIROLOGY

MicroRNA-19a enhances proliferation of bronchial epithelial cells by targetingTGFβR2gene in severe asthma

(2014) I. Haj-Salem et al.   ALLERGY

MicroRNA-146a and microRNA-146b expression and anti-inflammatory function in human airway smooth muscle

(2014) Brian S. Comer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Altered MicroRNA Expression of Nasal Mucosa in Long-Term Asthma and Allergic Rhinitis

(2014) Hille Suojalehto et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

MicroRNA-146a and MicroRNA-146b Regulate Human Dendritic Cell Apoptosis and Cytokine Production by Targeting TRAF6 and IRAK1 Proteins

(2014) Haein Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Activation-associated MicroRNA Accumulation Rates during Monocyte-to-macrophage Differentiation

(2014) Renee L. Eigsti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In Vivo Activity of MiR-34a Mimics Delivered by Stable Nucleic Acid Lipid Particles (SNALPs) against Multiple Myeloma

(2014) Maria Teresa Di Martino et al.   PLoS One

A MicroRNA Network Dysregulated in Asthma Controls IL-6 Production in Bronchial Epithelial Cells

(2014) Rocio T. Martinez-Nunez et al.   PLoS One

STAT3 Induction of miR-146b Forms a Feedback Loop to Inhibit the NF- B to IL-6 Signaling Axis and STAT3-Driven Cancer Phenotypes

(2014) M. Xiang et al.   Science Signaling

Myeloid Malignancies with Chromosome 5q Deletions Acquire a Dependency on an Intrachromosomal NF-κB Gene Network

(2014) Jing Fang et al.   Cell Reports

MicroRNAs: New Regulators of Toll-Like Receptor Signalling Pathways

(2014) Xiaobing He et al.   Biomed Research International

STAT3 Activity and Function in Cancer: Modulation by STAT5 and miR-146b

(2014) Sarah Walker et al.   Cancers

MicroRNA-34b promoter hypermethylation induces CREB overexpression and contributes to myeloid transformation

(2013) M. Pigazzi et al.   HAEMATOLOGICA

MicroRNAs responsive to Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis LPS modulate expression of genes regulating innate immunity in human macrophages

(2013) Afsar R Naqvi et al.   Innate Immunity

MicroRNA-9 regulates the expression of peroxisome proliferator-activated receptor δ in human monocytes during the inflammatory response

(2013) PETRA THULIN et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients

(2013) Bettina Levänen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Differential expression of microRNAs in exhaled breath condensates of patients with asthma, patients with chronic obstructive pulmonary disease, and healthy adults

(2013) Mark Pinkerton et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages

(2013) Takashi Satoh et al.   NATURE

MicroRNA-19a-3p inhibits breast cancer progression and metastasis by inducing macrophage polarization through downregulated expression of Fra-1 proto-oncogene

(2013) J Yang et al.   ONCOGENE

Next-generation sequencing of microRNAs uncovers expression signatures in polarized macrophages

(2013) Viviana Cobos Jiménez et al.   PHYSIOLOGICAL GENOMICS

IL-4/IL-13-Dependent and Independent Expression of miR-124 and Its Contribution to M2 Phenotype of Monocytic Cells in Normal Conditions and during Allergic Inflammation

(2013) Tatyana Veremeyko et al.   PLoS One

Negative regulation of Toll-like receptor 4 signaling by IL-10-dependent microRNA-146b

(2013) G. Curtale et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-mediated control of macrophages and its implications for cancer

(2013) Mario Leonardo Squadrito et al.   TRENDS IN IMMUNOLOGY

Airway Epithelial miRNA Expression Is Altered in Asthma

(2012) Owen D. Solberg et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Distinct MicroRNA Expression in Human Airway Cells of Asthmatic Donors Identifies a Novel Asthma-Associated Gene

(2012) Melanie J. Jardim et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Allergic contact dermatitis induces upregulation of identical microRNAs in humans and mice

(2012) Marie T. Vennegaard et al.   CONTACT DERMATITIS

Identifying Functional MicroRNAs in Macrophages with Polarized Phenotypes

(2012) Joel W. Graff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional implications of microRNAs in acute myeloid leukemia by integrating microRNA and messenger RNA expression profiling

(2011) Violaine Havelange et al.   CANCER

Inhibition of house dust mite–induced allergic airways disease by antagonism of microRNA-145 is comparable to glucocorticoid treatment

(2011) Adam Collison et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

MicroRNA Expression Profiles of Human Blood Monocyte-derived Dendritic Cells and Macrophages Reveal miR-511 as Putative Positive Regulator of Toll-like Receptor 4

(2011) Liina Tserel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-23 Receptor Regulation by Let-7f in Human CD4+ Memory T Cells

(2011) Z. Li et al.   JOURNAL OF IMMUNOLOGY

Regulation of Neutrophil Senescence by MicroRNAs

(2011) Jon R. Ward et al.   PLoS One

The Interleukin 13 (IL-13) Pathway in Human Macrophages Is Modulated by MicroRNA-155 via Direct Targeting of Interleukin 13 Receptor α1 (IL13Rα1)

(2010) Rocio T. Martinez-Nunez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-10 Inhibits miR-155 Induction by Toll-like Receptors

(2010) Claire E. McCoy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA Regulation of IFN-β Protein Expression: Rapid and Sensitive Modulation of the Innate Immune Response

(2010) Kenneth W. Witwer et al.   JOURNAL OF IMMUNOLOGY

MicroRNAs modulate the noncanonical transcription factor NF-κB pathway by regulating expression of the kinase IKKα during macrophage differentiation

(2010) Tao Li et al.   NATURE IMMUNOLOGY

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

(2009) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

Estradiol-regulated microRNAs control estradiol response in breast cancer cells

(2009) Poornima Bhat-Nakshatri et al.   NUCLEIC ACIDS RESEARCH

MicroRNA Expression Profiling in Mild Asthmatic Human Airways and Effect of Corticosteroid Therapy

(2009) Andrew E. Williams et al.   PLoS One

Regulation of progenitor cell proliferation and granulocyte function by microRNA-223

(2008) Jonathan B. Johnnidis et al.   NATURE

The let-7 family of microRNAs

(2008) Sarah Roush et al.   TRENDS IN CELL BIOLOGY