Cancer Stem Cells in Neuroblastoma: Expanding the Therapeutic Frontier
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Title
Cancer Stem Cells in Neuroblastoma: Expanding the Therapeutic Frontier
Authors
Keywords
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Journal
Frontiers in Molecular Neuroscience
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-05-27
DOI
10.3389/fnmol.2019.00131
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Note: Only part of the references are listed.- Antiproliferative and apoptotic effect of LY2090314, a GSK-3 inhibitor, in neuroblastoma in vitro
- (2018) Selvi Kunnimalaiyaan et al. BMC CANCER
- Tumorigenic proteins upregulated in the MYCN-amplified IMR-32 human neuroblastoma cells promote proliferation and migration
- (2018) Hayat Zaatiti et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Notch-1-PTEN-ERK1/2 signaling axis promotes HER2+ breast cancer cell proliferation and stem cell survival
- (2018) Andrew Baker et al. ONCOGENE
- FGFR1-ERK1/2-SOX2 axis promotes cell proliferation, epithelial–mesenchymal transition, and metastasis in FGFR1-amplified lung cancer
- (2018) Kaixuan Wang et al. ONCOGENE
- Exosomes Released by Gastric Cancer Cells Induce Transition of Pericytes Into Cancer-Associated Fibroblasts
- (2018) Xiaofei Ning et al. MEDICAL SCIENCE MONITOR
- The Akt/mTOR pathway in cancer stem/progenitor cells is a potential therapeutic target for glioblastoma and neuroblastoma
- (2018) Hisham F. Bahmad et al. Oncotarget
- Concise Reviews: Cancer Stem Cell Targeted Therapies: Toward Clinical Success
- (2018) Amar Desai et al. Stem Cells Translational Medicine
- Epigenetics in cancer stem cells
- (2017) Tan Boon Toh et al. Molecular Cancer
- Role of MEK partner-1 in cancer stemness through MEK/ERK pathway in cancerous neural stem cells, expressing EGFRviii
- (2017) Soo-Jung Kwon et al. Molecular Cancer
- ING5 activity in self-renewal of glioblastoma stem cells via calcium and follicle stimulating hormone pathways
- (2017) F Wang et al. ONCOGENE
- Anti-cancer stemness and anti-invasive activity of bitter taste receptors, TAS2R8 and TAS2R10, in human neuroblastoma cells
- (2017) Yoona Seo et al. PLoS One
- LGR5 promotes cancer stem cell traits and chemoresistance in cervical cancer
- (2017) Hao-Zhe Cao et al. Cell Death & Disease
- Correction: LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma
- (2017) Gabriella Cunha Vieira et al. Oncotarget
- FTY-720 induces apoptosis in neuroblastoma via multiple signaling pathways
- (2017) Ingo Lange et al. Oncotarget
- Retinoic acid and TGF-β signalling cooperate to overcome MYCN-induced retinoid resistance
- (2017) David J. Duffy et al. Genome Medicine
- Dissecting the role of AMP-activated protein kinase in human diseases
- (2017) Jin Li et al. Acta Pharmaceutica Sinica B
- Promoter hypermethylation as a mechanism for Lamin A/C silencing in a subset of neuroblastoma cells
- (2017) Ines Rauschert et al. PLoS One
- Intestinal cancer stem cells marked by Bmi1 or Lgr5 expression contribute to tumor propagation via clonal expansion
- (2017) Hirotsugu Yanai et al. Scientific Reports
- Induced differentiation inhibits sphere formation in neuroblastoma
- (2016) Brian T. Craig et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Retinoic acid receptor β enhanced the anti-cancer stem cells effect of β-carotene by down-regulating expression of delta-like 1 homologue in human neuroblastoma cells
- (2016) Yoo-Sun Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Aldehyde dehydrogenase activity plays a Key role in the aggressive phenotype of neuroblastoma
- (2016) Marjorie Flahaut et al. BMC CANCER
- Probenecid Sensitizes Neuroblastoma Cancer Stem Cells to Cisplatin
- (2016) Denise Campos-Arroyo et al. CANCER INVESTIGATION
- Preclinical Assessment of CD171-Directed CAR T-cell Adoptive Therapy for Childhood Neuroblastoma: CE7 Epitope Target Safety and Product Manufacturing Feasibility
- (2016) Annette Künkele et al. CLINICAL CANCER RESEARCH
- L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression
- (2016) Johnny Rached et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies
- (2016) Marco Ruella et al. JOURNAL OF CLINICAL INVESTIGATION
- Key role of MEK/ERK pathway in sustaining tumorigenicity and in vitro radioresistance of embryonal rhabdomyosarcoma stem-like cell population
- (2016) Carmela Ciccarelli et al. Molecular Cancer
- Combined Treatments with a Retinoid Receptor Agonist and Epigenetic Modulators in Human Neuroblastoma Cells
- (2016) Viviane Rösner Almeida et al. MOLECULAR NEUROBIOLOGY
- Berberine induces neuronal differentiation through inhibition of cancer stemness and epithelial-mesenchymal transition in neuroblastoma cells
- (2016) C.R. Naveen et al. PHYTOMEDICINE
- L1 Cell Adhesion Molecule-Specific Chimeric Antigen Receptor-Redirected Human T Cells Exhibit Specific and Efficient Antitumor Activity against Human Ovarian Cancer in Mice
- (2016) Hao Hong et al. PLoS One
- Erratum: Differentiation of human neuroblastoma cells toward the osteogenic lineage by mTOR inhibitor
- (2016) A Carpentieri et al. Cell Death & Disease
- The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models
- (2016) Kristian W. Pajtler et al. Oncotarget
- Valproic Acid Increases CD133 Positive Cells that Show Low Sensitivity to Cytostatics in Neuroblastoma
- (2016) Mohamed Ashraf Khalil et al. PLoS One
- Targeting CD123 in acute myeloid leukemia using a T-cell-directed dual-affinity retargeting platform
- (2015) M. Al-Hussaini et al. BLOOD
- Stem cell maintenance by manipulating signaling pathways: past, current and future
- (2015) Xi Chen et al. BMB Reports
- G-CSF Promotes Neuroblastoma Tumorigenicity and Metastasis via STAT3-Dependent Cancer Stem Cell Activation
- (2015) S. Agarwal et al. CANCER RESEARCH
- Descriptive analysis of tumor cells with stem like phenotypes in metastatic and benign adrenal tumors
- (2015) Todd Jensen et al. JOURNAL OF PEDIATRIC SURGERY
- Stem cells and the evolving notion of cellular identity
- (2015) George Q. Daley PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Microenvironmental Modulation of Decorin and Lumican in Temozolomide-Resistant Glioblastoma and Neuroblastoma Cancer Stem-Like Cells
- (2015) Cristiano Farace et al. PLoS One
- A distinct gene expression signature characterizes human neuroblastoma cancer stem cells
- (2015) Robert A. Ross et al. Stem Cell Research
- LGR5 Promotes Breast Cancer Progression and Maintains Stem-Like Cells Through Activation of Wnt/β-Catenin Signaling
- (2015) Lu Yang et al. STEM CELLS
- Chemoresistance, Cancer Stem Cells, and miRNA Influences: The Case for Neuroblastoma
- (2015) Alfred Buhagiar et al. Analytical Cellular Pathology
- TRPM7 maintains progenitor-like features of neuroblastoma cells: implications for metastasis formation
- (2015) Jeroen Middelbeek et al. Oncotarget
- Down-regulation of the Lamin A/C in neuroblastoma triggers the expansion of tumor initiating cells
- (2015) Marta Nardella et al. Oncotarget
- Inhibition of hypoxia inducible factors combined with all-trans retinoic acid treatment enhances glial transdifferentiation of neuroblastoma cells
- (2015) Flora Cimmino et al. Scientific Reports
- Perhexiline maleate enhances antitumor efficacy of cisplatin in neuroblastoma by inducing over-expression of NDM29 ncRNA
- (2015) Serena Vella et al. Scientific Reports
- Metformin and Ara-a Effectively Suppress Brain Cancer by Targeting Cancer Stem/Progenitor Cells
- (2015) Tarek H. Mouhieddine et al. Frontiers in Neuroscience
- Cancer Stem Cells and Their Interaction with the Tumor Microenvironment in Neuroblastoma
- (2015) Evan Garner et al. Cancers
- JARID1B Expression Plays a Critical Role in Chemoresistance and Stem Cell-Like Phenotype of Neuroblastoma Cells
- (2015) Yung-Ting Kuo et al. PLoS One
- Frizzled receptor 6 marks rare, highly tumourigenic stem-like cells in mouse and human neuroblastomas.
- (2015) Sandra Cantilena et al. Oncotarget
- Targeting ornithine decarboxylase reverses the LIN28/Let-7 axis and inhibits glycolytic metabolism in neuroblastoma
- (2015) Ann M. Lozier et al. Oncotarget
- In Vivo Antitumor and Antimetastatic Activity of Sunitinib in Preclinical Neuroblastoma Mouse Model
- (2015) Libo Zhang et al. NEOPLASIA
- Functional Sphere Profiling Reveals the Complexity of Neuroblastoma Tumor-Initiating Cell Model
- (2015) Aurélie Coulon et al. NEOPLASIA
- Role of AMP-Activated Protein Kinase in Cancer Therapy
- (2014) Gauhar Rehman et al. ARCHIV DER PHARMAZIE
- β-Carotene inhibits neuroblastoma tumorigenesis by regulating cell differentiation and cancer cell stemness
- (2014) Ji Ye Lim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cancer cell resistance mechanisms: a mini review
- (2014) S. Al-Dimassi et al. Clinical & Translational Oncology
- The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength
- (2014) W. de Lau et al. GENES & DEVELOPMENT
- Identification of compounds that selectively target highly chemotherapy refractory neuroblastoma cancer stem cells
- (2014) David Díaz-Carballo et al. INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
- Involvement of aldehyde dehydrogenase 1A2 in the regulation of cancer stem cell properties in neuroblastoma
- (2014) TRI BUDI HARTOMO et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- XAV939 inhibits the stemness and migration of neuroblastoma cancer stem cells via repression of tankyrase 1
- (2014) XIAOHONG TIAN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Diverse Solid Tumors Expressing a Restricted Epitope of L1-CAM Can Be Targeted by Chimeric Antigen Receptor Redirected T Lymphocytes
- (2014) Hao Hong et al. JOURNAL OF IMMUNOTHERAPY
- A Phase 1 study of the safety, pharmacokinetics and anti-leukemic activity of the anti-CD123 monoclonal antibody CSL360 in relapsed, refractory or high-risk acute myeloid leukemia
- (2014) Simon Z. He et al. LEUKEMIA & LYMPHOMA
- Prokineticin signaling is required for the maintenance of a de novo population of c-KIT+ cells to sustain neuroblastoma progression
- (2014) S-T Lau et al. ONCOGENE
- The TrkAIII Oncoprotein Inhibits Mitochondrial Free Radical ROS-Induced Death of SH-SY5Y Neuroblastoma Cells by Augmenting SOD2 Expression and Activity at the Mitochondria, within the Context of a Tumour Stem Cell-like Phenotype
- (2014) Pierdomenico Ruggeri et al. PLoS One
- TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival
- (2014) P L Chavali et al. Cell Death & Disease
- Expression and prognostic significance of Oct4 and Nanog in neuroblastoma
- (2013) Maryam Monajemzadeh et al. APMIS
- G-CSF Receptor Positive Neuroblastoma Subpopulations Are Enriched in Chemotherapy-Resistant or Relapsed Tumors and Are Highly Tumorigenic
- (2013) Danielle M. Hsu et al. CANCER RESEARCH
- LGR5 positivity defines stem-like cells in colorectal cancer
- (2013) Daniela Hirsch et al. CARCINOGENESIS
- Identification of a putative transcriptome signature common to neuroblastoma and neural crest cells
- (2013) M. Angeles Rabadán et al. Developmental Neurobiology
- Cytotoxicity and inhibition of intercellular interaction in N2a neurospheroids by perfluorooctanoic acid and perfluorooctanesulfonic acid
- (2013) Seong-Kyoon Choi et al. FOOD AND CHEMICAL TOXICOLOGY
- Identification of Small Molecule Inhibitors of Jumonji AT-rich Interactive Domain 1B (JARID1B) Histone Demethylase by a Sensitive High Throughput Screen
- (2013) Joyce Sayegh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Notch Signaling–related Therapeutic Strategies With Novel Drugs in Neuroblastoma Spheroids
- (2013) Sule Ayla et al. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
- Interaction of Delta-like 1 Homolog ( Drosophila ) with Prohibitins and Its Impact on Tumor Cell Clonogenicity
- (2013) Asma Begum et al. MOLECULAR CANCER RESEARCH
- Effect of β-carotene on cancer cell stemness and differentiation in SK-N-BE(2)C neuroblastoma cells
- (2013) HYUN AH LEE et al. ONCOLOGY REPORTS
- Targeting Neuroblastoma Stem Cells with Retinoic Acid and Proteasome Inhibitor
- (2013) Barbara Hämmerle et al. PLoS One
- Transient treatment with epigenetic modifiers yields stable neuroblastoma stem cells resembling aggressive large-cell neuroblastomas
- (2013) N. Ikegaki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Differential effect of long-term drug selection with doxorubicin and vorinostat on neuroblastoma cells with cancer stem cell characteristics
- (2013) X Zheng et al. Cell Death & Disease
- MYCN and the epigenome
- (2013) Stanley He et al. Frontiers in Oncology
- LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem-Like Cells
- (2012) Susumu Nakata et al. BRAIN PATHOLOGY
- TRPM7 Is Required for Breast Tumor Cell Metastasis
- (2012) Jeroen Middelbeek et al. CANCER RESEARCH
- Role of Wnt/β-catenin Signaling in Drug Resistance of Pancreatic Cancer
- (2012) Jiujie Cui et al. CURRENT PHARMACEUTICAL DESIGN
- Expression of Stem Cell Markers, CD133 and CD44, in Pediatric Solid Tumors: A Study Using Tissue Microarray
- (2012) Mitra Mehrazma et al. Fetal and Pediatric Pathology
- Genotype analysis of tumor-initiating cells expressing CD133 in neuroblastoma
- (2012) Sonia Cournoyer et al. GENES CHROMOSOMES & CANCER
- CD133 expression is associated with poor outcome in neuroblastoma via chemoresistance mediated by the AKT pathway
- (2012) Hervé Sartelet et al. HISTOPATHOLOGY
- Sodium valproate potentiates staurosporine-induced apoptosis in neuroblastoma cells via Akt/survivin independently of HDAC inhibition
- (2012) Reecha D. Shah et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Zoledronate Sensitizes Neuroblastoma-derived Tumor-initiating Cells to Cytolysis Mediated by Human γδ T Cells
- (2012) Nobuhiro Nishio et al. JOURNAL OF IMMUNOTHERAPY
- Epigenetic alterations involved in cancer stem cell reprogramming
- (2012) Purificación Muñoz et al. Molecular Oncology
- ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
- (2012) Huai-Xiang Hao et al. NATURE
- β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer
- (2012) Stephan P Tenbaum et al. NATURE MEDICINE
- The neural adhesion molecule L1CAM confers chemoresistance in human glioblastomas
- (2012) Janka Held-Feindt et al. NEUROCHEMISTRY INTERNATIONAL
- Mulberry Leaf Extract Inhibits Cancer Cell Stemness in Neuroblastoma
- (2012) Seolhyun Park et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation
- (2012) M Calao et al. ONCOGENE
- Epigenetic regulation of the neuroblastoma genes, Arid3b and Mycn
- (2012) K Kobayashi et al. ONCOGENE
- Intermittent Hypoxia Regulates Stem-like Characteristics and Differentiation of Neuroblastoma Cells
- (2012) Vasantha Kumar Bhaskara et al. PLoS One
- Small Molecule Antagonists of the Wnt/Beta-Catenin Signaling Pathway Target Breast Tumor-Initiating Cells in a Her2/Neu Mouse Model of Breast Cancer
- (2012) Robin M. Hallett et al. PLoS One
- H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence
- (2012) A. Chicas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Wnt pathway activity confers chemoresistance to cancer stem-like cells in a neuroblastoma cell line
- (2012) Sharada D. Vangipuram et al. TUMOR BIOLOGY
- Reversible adaptive plasticity: a mechanism for neuroblastoma cell heterogeneity and chemo-resistance
- (2012) Lina Chakrabarti Frontiers in Oncology
- The role and therapeutic potential of prohibitin in disease
- (2011) Arianne L. Theiss et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Small Molecule Kinase Inhibitor Screen Identifies Polo-Like Kinase 1 as a Target for Neuroblastoma Tumor-Initiating Cells
- (2011) Natalie Grinshtein et al. CANCER RESEARCH
- Binding of the JmjC Demethylase JARID1B to LSD1/NuRD Suppresses Angiogenesis and Metastasis in Breast Cancer Cells by Repressing Chemokine CCL14
- (2011) Q. Li et al. CANCER RESEARCH
- Molecular Targeting of Neural Cancer Stem Cells: TTAGGG, You're It!
- (2011) A. B. Hjelmeland et al. CLINICAL CANCER RESEARCH
- Neural Tumor-Initiating Cells Have Distinct Telomere Maintenance and Can be Safely Targeted for Telomerase Inhibition
- (2011) P. Castelo-Branco et al. CLINICAL CANCER RESEARCH
- Endosialin: A novel malignant cell therapeutic target for neuroblastoma
- (2011) Beverly Teicher INTERNATIONAL JOURNAL OF ONCOLOGY
- Wnt activation is implicated in glioblastoma radioresistance
- (2011) Yonghyun Kim et al. LABORATORY INVESTIGATION
- Resistance or sensitivity of Wilms’ tumor to anti-FZD7 antibody highlights the Wnt pathway as a possible therapeutic target
- (2011) N Pode-Shakked et al. ONCOGENE
- The channel kinase, TRPM7, is required for early embryonic development
- (2011) J. Jin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Analysis of nuclear nestin localization in cell lines derived from neurogenic tumors
- (2011) Olga Krupkova et al. TUMOR BIOLOGY
- Neuroblastoma cells negative for CD44 possess tumor-initiating properties
- (2011) Elena K. Siapati et al. CELLULAR ONCOLOGY
- Epigallocatechin gallate inhibits sphere formation of neuroblastoma BE(2)-C cells
- (2011) Noriyuki Nishimura et al. Environmental Health and Preventive Medicine
- Screening a panel of drugs with diverse mechanisms of action yields potential therapeutic agents against neuroblastoma
- (2010) Jinesh S. Gheeya et al. CANCER BIOLOGY & THERAPY
- System-Level Analysis of Neuroblastoma Tumor-Initiating Cells Implicates AURKB as a Novel Drug Target for Neuroblastoma
- (2010) O. Morozova et al. CLINICAL CANCER RESEARCH
- Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens
- (2010) Kristen M. Smith et al. EMBO Molecular Medicine
- Nuclear Orphan Receptor TLX Induces Oct-3/4 for the Survival and Maintenance of Adult Hippocampal Progenitors upon Hypoxia
- (2010) Pavithra Lakshminarasimhan Chavali et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2010) Sayuri Suzuki et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Enhancement of vinorelbine-induced cytotoxicity and apoptosis by clomipramine and lithium chloride in human neuroblastoma cancer cell line SH-SY5Y
- (2010) Ayhan Bilir et al. JOURNAL OF NEURO-ONCOLOGY
- ABCG2: A potential marker of stem cells and novel target in stem cell and cancer therapy
- (2010) Xi-wei Ding et al. LIFE SCIENCES
- Curcumin, the Golden Spice From Indian Saffron, Is a Chemosensitizer and Radiosensitizer for Tumors and Chemoprotector and Radioprotector for Normal Organs
- (2010) Ajay Goel et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Effect of retinoic acid and delta-like 1 homologue (DLK1) on differentiation in neuroblastoma
- (2010) Yuri Kim Nutrition Research and Practice
- CD133 suppresses neuroblastoma cell differentiation via signal pathway modification
- (2010) H Takenobu et al. ONCOGENE
- Association of telomerase activity with radio- and chemosensitivity of neuroblastomas
- (2010) Simone Wesbuer et al. Radiation Oncology
- Hypoxia-Regulated Delta-like 1 Homologue Enhances Cancer Cell Stemness and Tumorigenicity
- (2009) Y. Kim et al. CANCER RESEARCH
- Resistance of stem-like cells from neuroblastoma cell lines to commonly used chemotherapeutic agents
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- (2008) S. Bao et al. CANCER RESEARCH
- Identification of ALK as a major familial neuroblastoma predisposition gene
- (2008) Yaël P. Mossé et al. NATURE
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- (2008) J. Jin et al. SCIENCE
- Hypoxia Enhances Tumor Stemness by Increasing the Invasive and Tumorigenic Side Population Fraction
- (2008) Bikul Das et al. STEM CELLS
- Expression and clinical significance of stem cell marker CD133 in human neuroblastoma
- (2008) Qiang-Song Tong et al. World Journal of Pediatrics
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