Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation

Chemotherapy-Induced Apoptosis in a Transgenic Model of Neuroblastoma Proceeds Through p53 Induction

(2015) Louis Chesler et al.   NEOPLASIA

Mdm2 Deficiency Suppresses MYCN-Driven Neuroblastoma Tumorigenesis In Vivo

(2015) Zaowen Chen et al.   NEOPLASIA

p53 Is a Direct Transcriptional Target of MYCN in Neuroblastoma

(2010) L. Chen et al.   CANCER RESEARCH

Polycomb group proteins

(2010) Mo K. Kang   CELL CYCLE

Bmi1 is a MYCN target gene that regulates tumorigenesis through repression of KIF1Bβ and TSLC1 in neuroblastoma

(2010) H Ochiai et al.   ONCOGENE

Bmi-1, stem cells and cancer

(2009) L. Jiang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Embryonal neural tumours and cell death

(2009) John Inge Johnsen et al.   APOPTOSIS

Targeted depletion of BMI1 sensitizes tumor cells to P53-mediated apoptosis in response to radiation therapy

(2009) N M Alajez et al.   CELL DEATH AND DIFFERENTIATION

Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression

(2009) W D Thomas et al.   ONCOGENE

The E3 Ubiquitin-Ligase Bmi1/Ring1A Controls the Proteasomal Degradation of Top2α Cleavage Complex – A Potentially New Drug Target

(2009) Iris Alchanati et al.   PLoS One

Medulloblastoma Can Be Initiated by Deletion of Patched in Lineage-Restricted Progenitors or Stem Cells

(2008) Zeng-Jie Yang et al.   CANCER CELL