LGR5 promotes cancer stem cell traits and chemoresistance in cervical cancer

SRY and OCT4 Are Required for the Acquisition of Cancer Stem Cell-Like Properties and Are Potential Differentiation Therapy Targets

(2015) Shigekazu Murakami et al.   STEM CELLS

High aldehyde dehydrogenase activity identifies cancer stem cells in human cervical cancer

(2015) Shuyan Liu et al.   Oncotarget

LGR5 promotes the proliferation and tumor formation of cervical cancer cells through the Wnt/β-catenin signaling pathway

(2015) Qing Chen et al.   Oncotarget

Lgr5 promotes cancer stemness and confers chemoresistance through ABCB1 in colorectal cancer

(2013) Yi-Shiuan Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

LGR5 positivity defines stem-like cells in colorectal cancer

(2013) Daniela Hirsch et al.   CARCINOGENESIS

LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE 2 : implications for targeting adenoma stem cells with NSAIDs

(2013) Manal R.A. Al-Kharusi et al.   CARCINOGENESIS

Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche

(2013) Andrea Flesken-Nikitin et al.   NATURE

OCT4 promotes tumorigenesis and inhibits apoptosis of cervical cancer cells by miR-125b/BAK1 pathway

(2013) Y-D Wang et al.   Cell Death & Disease

LGR5 is Expressed by Ewing Sarcoma and Potentiates Wnt/β-Catenin Signaling

(2013) Christopher A. Scannell et al.   Frontiers in Oncology

Cytoplasmic NANOG-Positive Stromal Cells Promote Human Cervical Cancer Progression

(2012) Ting-Ting Gu et al.   AMERICAN JOURNAL OF PATHOLOGY

LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem-Like Cells

(2012) Susumu Nakata et al.   BRAIN PATHOLOGY

Monoclonal Antibodies Against Lgr5 Identify Human Colorectal Cancer Stem Cells

(2012) Kristel Kemper et al.   STEM CELLS

Cancer Stem Cell Marker Bmi-1 Expression is Associated with Basal-like Phenotype and Poor Survival in Breast Cancer

(2012) Yanyang Wang et al.   WORLD JOURNAL OF SURGERY

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Krüppel-like factor 4 functions as a tumor suppressor in cervical carcinoma

(2011) Wen-Ting Yang et al.   CANCER

Breast cancer stem cells: treatment resistance and therapeutic opportunities

(2011) Fares Al-Ejeh et al.   CARCINOGENESIS

Kruppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion

(2011) F Yu et al.   ONCOGENE

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/ -catenin signaling

(2011) K. S. Carmon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt/β-catenin Signaling in Normal and Cancer Stem Cells

(2011) Kenneth C. Valkenburg et al.   Cancers

Leucine-Rich Repeat-Containing G-Protein-Coupled Receptors as Markers of Adult Stem Cells

(2010) Nick Barker et al.   GASTROENTEROLOGY

Expression of Sox2 in human cervical carcinogenesis

(2010) Jing Ji et al.   HUMAN PATHOLOGY

Wnt signaling in stem and cancer stem cells

(2010) Peter Wend et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Lgr5, an intestinal stem cell marker, is abnormally expressed in Barrett's esophagus and esophageal adenocarcinoma

(2009) L. Becker et al.   DISEASES OF THE ESOPHAGUS

Detección y tipificación de virus papiloma humano en adenocarcinoma de cuello uterino mediante reverse line blot, Región de La Araucanía, Chile

(2009) Priscilla Brebi M et al.   REVISTA MEDICA DE CHILE

G-Protein-Coupled Receptor GPR49 is Up-regulated in Basal Cell Carcinoma and Promotes Cell Proliferation and Tumor Formation

(2008) Keiji Tanese et al.   AMERICAN JOURNAL OF PATHOLOGY

Lgr5 marks cycling, yet long-lived, hair follicle stem cells

(2008) Viljar Jaks et al.   NATURE GENETICS