Wnt pathway activity confers chemoresistance to cancer stem-like cells in a neuroblastoma cell line

Frizzled receptor 6 marks rare, highly tumourigenic stem-like cells in mouse and human neuroblastomas.

(2015) Sandra Cantilena et al.   Oncotarget

Functional Sphere Profiling Reveals the Complexity of Neuroblastoma Tumor-Initiating Cell Model

(2015) Aurélie Coulon et al.   NEOPLASIA

Markers of the APC/ -Catenin Signaling Pathway as Potential Treatable, Preneoplastic Biomarkers of Risk for Colorectal Neoplasms

(2012) T. U. Ahearn et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Role of Wnt/β-catenin Signaling in Drug Resistance of Pancreatic Cancer

(2012) Jiujie Cui et al.   CURRENT PHARMACEUTICAL DESIGN

Genotype analysis of tumor-initiating cells expressing CD133 in neuroblastoma

(2012) Sonia Cournoyer et al.   GENES CHROMOSOMES & CANCER

CD133 expression is associated with poor outcome in neuroblastoma via chemoresistance mediated by the AKT pathway

(2012) Hervé Sartelet et al.   HISTOPATHOLOGY

NEU4L sialidase overexpression promotes β-catenin signaling in neuroblastoma cells, enhancing stem-like malignant cell growth

(2012) Cristina Tringali et al.   INTERNATIONAL JOURNAL OF CANCER

Targeted inhibition of T-cell factor activity promotes syndecan-2 expression and sensitization to doxorubicin in osteosarcoma cells and bone tumors in mice

(2012) François-Xavier Dieudonné et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Aberrant nuclear localization of EBP50 promotes colorectal carcinogenesis in xenotransplanted mice by modulating TCF-1 and β-catenin interactions

(2012) Yu-Yu Lin et al.   JOURNAL OF CLINICAL INVESTIGATION

β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer

(2012) Stephan P Tenbaum et al.   NATURE MEDICINE

Role of stemness-related molecules in neuroblastoma

(2012) Takehiko Kamijo   PEDIATRIC RESEARCH

Small Molecule Antagonists of the Wnt/Beta-Catenin Signaling Pathway Target Breast Tumor-Initiating Cells in a Her2/Neu Mouse Model of Breast Cancer

(2012) Robin M. Hallett et al.   PLoS One

Inhibition of the sonic hedgehog pathway by cyplopamine reduces the CD133+/CD15+ cell compartment and the in vitro tumorigenic capability of neuroblastoma cells

(2011) Paula Schiapparelli et al.   CANCER LETTERS

Frizzled 4 Regulates Stemness and Invasiveness of Migrating Glioma Cells Established by Serial Intracranial Transplantation

(2011) X. Jin et al.   CANCER RESEARCH

Stem Cell Pathways Contribute to Clinical Chemoresistance in Ovarian Cancer

(2011) A. D. Steg et al.   CLINICAL CANCER RESEARCH

The Gamma Catenin/CBP Complex Maintains Survivin Transcription in β-catenin Deficient/Depleted Cancer Cells

(2011) Y.-M. Kim et al.   CURRENT CANCER DRUG TARGETS

Role of canonical Wnt signaling in endometrial carcinogenesis

(2011) Thanh H Dellinger et al.   Expert Review of Anticancer Therapy

Protein kinase C in Wnt signaling: Implications in cancer initiation and progression

(2011) Luis Bernardo Luna-Ulloa et al.   IUBMB LIFE

Expression profile of frizzled receptors in human medulloblastomas

(2011) Ettore Salsano et al.   JOURNAL OF NEURO-ONCOLOGY

Wnt activation is implicated in glioblastoma radioresistance

(2011) Yonghyun Kim et al.   LABORATORY INVESTIGATION

Wnt3 gene expression promotes tumor progression in non-small cell lung cancer

(2011) Nariyasu Nakashima et al.   LUNG CANCER

Resistance or sensitivity of Wilms’ tumor to anti-FZD7 antibody highlights the Wnt pathway as a possible therapeutic target

(2011) N Pode-Shakked et al.   ONCOGENE

Enhancement of Canonical Wnt/β-Catenin Signaling Activity by HCV Core Protein Promotes Cell Growth of Hepatocellular Carcinoma Cells

(2011) Jiao Liu et al.   PLoS One

Temporal blastemal cell gene expression analysis in the kidney reveals new Wnt and related signaling pathway genes to be essential for Wilms' tumor onset

(2011) M Maschietto et al.   Cell Death & Disease

Ethanol Alters Cell Fate of Fetal Human Brain-Derived Stem and Progenitor Cells

(2010) Sharada D. Vangipuram et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

FZD4 as a Mediator of ERG Oncogene-Induced WNT Signaling and Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells

(2010) S. Gupta et al.   CANCER RESEARCH

Regulation of Lrp6 phosphorylation

(2010) Christof Niehrs et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cancer stem cells: the theory and perspectives in cancer therapy

(2010) Justyna Gil et al.   JOURNAL OF APPLIED GENETICS

Targeting cancer stem cells by inhibiting Wnt, Notch and Hedgehog pathways

(2010) Naoko Takebe et al.   Nature Reviews Clinical Oncology

Association of telomerase activity with radio- and chemosensitivity of neuroblastomas

(2010) Simone Wesbuer et al.   Radiation Oncology

Dysregulation of Frizzled 6 is a critical component of B-cell leukemogenesis in a mouse model of chronic lymphocytic leukemia

(2009) Q.-L. Wu et al.   BLOOD

Cancer Stem Cells: The Emerging Challenge of Drug Targeting

(2009) Roger Besancon et al.   CURRENT MEDICINAL CHEMISTRY

Stem-like Cancer Cells Are Inducible by Increasing Genomic Instability in Cancer Cells

(2009) Yi Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Molecular Basis of Colorectal Cancer

(2009) Sanford D. Markowitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Resistance of stem-like cells from neuroblastoma cell lines to commonly used chemotherapeutic agents

(2009) Sharada D. Vangipuram et al.   PEDIATRIC BLOOD & CANCER

Neuroblastoma Cell Lines Contain Pluripotent Tumor Initiating Cells That Are Susceptible to a Targeted Oncolytic Virus

(2009) Yonatan Y. Mahller et al.   PLoS One

Recent advances in cancer stem cells

(2008) Robert W Cho et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Expression of Wnt4 in Human Pituitary Adenomas Regulates Activation of the β-Catenin-Independent Pathway

(2008) Takashi Miyakoshi et al.   ENDOCRINE PATHOLOGY