Anti-cancer stemness and anti-invasive activity of bitter taste receptors, TAS2R8 and TAS2R10, in human neuroblastoma cells

Selaginella uncinata flavonoids ameliorated ovalbumin-induced airway inflammation in a rat model of asthma

(2017) Bing Yu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Extraoral bitter taste receptors in health and disease

(2017) Ping Lu et al.   JOURNAL OF GENERAL PHYSIOLOGY

Bitter taste receptors: Novel insights into the biochemistry and pharmacology

(2016) Appalaraju Jaggupilli et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Bitter taste receptors: Extraoral roles in pathophysiology

(2016) Feroz Ahmed Shaik et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Purinergic signaling in Parkinson's disease. Relevance for treatment

(2016) Gemma Navarro et al.   NEUROPHARMACOLOGY

The bitter truth about bitter taste receptors: beyond sensing bitter in the oral cavity

(2015) B. Avau et al.   Acta Physiologica

Salicin from Willow Bark can Modulate Neurite Outgrowth in Human Neuroblastoma SH-SY5Y Cells

(2015) Ute Wölfle et al.   PHYTOTHERAPY RESEARCH

Cancer stem cells: An insight and future perspective

(2015) Sandeep Kaur et al.   Journal of Cancer Research and Therapeutics

Differential expression of bitter taste receptors in non-cancerous breast epithelial and breast cancer cells

(2014) Nisha Singh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

β-Carotene inhibits neuroblastoma tumorigenesis by regulating cell differentiation and cancer cell stemness

(2014) Ji Ye Lim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Salicin, an Extract from White Willow Bark, Inhibits Angiogenesis by Blocking the ROS-ERK Pathways

(2014) Chang-Seok Kong et al.   PHYTOTHERAPY RESEARCH

Diet-Induced Regulation of Bitter Taste Receptor Subtypes in the Mouse Gastrointestinal Tract

(2014) Gaia Vegezzi et al.   PLoS One

Understanding and targeting cancer stem cells: therapeutic implications and challenges

(2013) Ke Chen et al.   ACTA PHARMACOLOGICA SINICA

The Druggable Genome: Evaluation of Drug Targets in Clinical Trials Suggests Major Shifts in Molecular Class and Indication

(2013) Mathias Rask-Andersen et al.   Annual Review of Pharmacology and Toxicology

Mulberry Leaf Extract Inhibits Invasive Potential and Downregulates Hypoxia-Inducible Factor-1α (HIF-1α) in SK-N-BE(2)C Neuroblastoma Cells

(2013) Seolhyun PARK et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Functional Genomics Reveals Dysregulation of Cortical Olfactory Receptors in Parkinson Disease: Novel Putative Chemoreceptors in the Human Brain

(2013) Paula Garcia-Esparcia et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Anti-cancer activity of quercetin in neuroblastoma: an in vitro approach

(2013) E. Sugantha Priya et al.   NEUROLOGICAL SCIENCES

Extrasensory perception: Odorant and taste receptors beyond the nose and mouth

(2013) Simon R. Foster et al.   PHARMACOLOGY & THERAPEUTICS

Neuronal expression of bitter taste receptors and downstream signaling molecules in the rat brainstem

(2012) Ozra Dehkordi et al.   BRAIN RESEARCH

Transcriptome analysis reveals upregulation of bitter taste receptors in severe asthmatics

(2012) Christina Orsmark-Pietras et al.   EUROPEAN RESPIRATORY JOURNAL

Role of stemness-related molecules in neuroblastoma

(2012) Takehiko Kamijo   PEDIATRIC RESEARCH

Functional bitter taste receptors are expressed in brain cells

(2011) Nisha Singh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human Bitter Taste Receptors hTAS2R8 and hTAS2R39 with Differential Functions to Recognize Bitter Peptides

(2011) Yohei UENO et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

DLK1, delta-like 1 homolog (Drosophila), regulates tumor cell differentiation in vivo

(2011) Asma Begum et al.   CANCER LETTERS

Gene Expression Profiling of Fixed Tissues Identified Hypoxia-Inducible Factor-1α, VEGF, and Matrix Metalloproteinase-2 as Biomarkers of Lymph Node Metastasis in Hepatocellular Carcinoma

(2011) Zuo-Lin Xiang et al.   CLINICAL CANCER RESEARCH

BitterDB: a database of bitter compounds

(2011) Ayana Wiener et al.   NUCLEIC ACIDS RESEARCH

Bitter taste receptor T2R1 is activated by dipeptides and tripeptides

(2010) Jasbir Upadhyaya et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

GPR56 Plays varying roles in endogenous cancer progression

(2010) Lei Xu et al.   CLINICAL & EXPERIMENTAL METASTASIS

Comprehensive characterization of neuroblastoma cell line subtypes reveals bilineage potential similar to neural crest stem cells

(2009) Sandra Acosta et al.   BMC DEVELOPMENTAL BIOLOGY

Hypoxia-Regulated Delta-like 1 Homologue Enhances Cancer Cell Stemness and Tumorigenicity

(2009) Y. Kim et al.   CANCER RESEARCH

Common Sense about Taste: From Mammals to Insects

(2009) David A. Yarmolinsky et al.   CELL

The Molecular Receptive Ranges of Human TAS2R Bitter Taste Receptors

(2009) Wolfgang Meyerhof et al.   CHEMICAL SENSES

Allyl isothiocyanate as a cancer chemopreventive phytochemical

(2009) Yuesheng Zhang   MOLECULAR NUTRITION & FOOD RESEARCH

Regulation of matrix metalloproteinase-9 gene expression in MPP+- or 6-OHDA-treated human neuroblastoma SK-N-BE(2)C cells

(2009) So-Young Kim et al.   NEUROCHEMISTRY INTERNATIONAL

Neuroblastoma Cell Lines Contain Pluripotent Tumor Initiating Cells That Are Susceptible to a Targeted Oncolytic Virus

(2009) Yonatan Y. Mahller et al.   PLoS One

Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1  and -2 

(2008) M. Puppo et al.   MOLECULAR CANCER THERAPEUTICS

Structural diversity of G protein-coupled receptors and significance for drug discovery

(2008) Malin C. Lagerström et al.   NATURE REVIEWS DRUG DISCOVERY