Identification of Small Molecule Inhibitors of Jumonji AT-rich Interactive Domain 1B (JARID1B) Histone Demethylase by a Sensitive High Throughput Screen

Epigenetic Mechanisms in Commonly Occurring Cancers

(2012) Lauren P. Blair et al.   DNA AND CELL BIOLOGY

Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor

(2012) Line H. Kristensen et al.   FEBS Journal

Identification of catechols as histone-lysine demethylase inhibitors

(2012) Anders L. Nielsen et al.   FEBS LETTERS

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

(2012) Laurens Kruidenier et al.   NATURE

Antifungal activity of a series of 1,2-benzisothiazol-3(2H)-one derivatives

(2011) Dengfeng Dou et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Benzisothiazolones as modulators of macrophage migration inhibitory factor

(2011) William L. Jorgensen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Jarid1b targets genes regulating development and is involved in neural differentiation

(2011) Sandra U Schmitz et al.   EMBO JOURNAL

Lysine Demethylases Inhibitors

(2011) Takayoshi Suzuki et al.   JOURNAL OF MEDICINAL CHEMISTRY

The von Hippel–Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C

(2011) X Niu et al.   ONCOGENE

Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1

(2011) W. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer

(2011) Lauren P. Blair et al.   Cancers

Development of homogeneous luminescence assays for histone demethylase catalysis and binding

(2010) Akane Kawamura et al.   ANALYTICAL BIOCHEMISTRY

A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

(2010) Sreenath V. Sharma et al.   CELL

A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth

(2010) Alexander Roesch et al.   CELL

Inhibitors of the Salicylate Synthase (MbtI) from Mycobacterium tuberculosis Discovered by High-Throughput Screening

(2010) Mahalakshmi Vasan et al.   ChemMedChem

Structural insights into histone lysine demethylation

(2010) Haifeng Hou et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Selective Inhibitors of the JMJD2 Histone Demethylases: Combined Nondenaturing Mass Spectrometric Screening and Crystallographic Approaches

(2010) Nathan R. Rose et al.   JOURNAL OF MEDICINAL CHEMISTRY

New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

(2010) Jonathan B. Baell et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates

(2010) Armin Thalhammer et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors

(2010) Oliver N. F. King et al.   PLoS One

A miniaturized screen for inhibitors of Jumonji histone demethylases

(2009) Masaaki Sakurai et al.   Molecular BioSystems

Inhibitor Scaffolds for 2-Oxoglutarate-Dependent Histone Lysine Demethylases⊥

(2008) Nathan R. Rose et al.   JOURNAL OF MEDICINAL CHEMISTRY