Chemoresistance, Cancer Stem Cells, and miRNA Influences: The Case for Neuroblastoma

miRNA-558 promotes tumorigenesis and aggressiveness of neuroblastoma cells through activating the transcription of heparanase

(2015) Hongxia Qu et al.   HUMAN MOLECULAR GENETICS

Transcription Factors and microRNA-Co-Regulated Genes in Gastric Cancer Invasion in Ex Vivo

(2015) Yue Shi et al.   PLoS One

The p53 Isoform Δ133p53β Promotes Cancer Stem Cell Potential

(2015) Nikola Arsic et al.   Stem Cell Reports

MiR-520d-5p directly targets TWIST1 and downregulates the metastamiR miR-10b

(2015) Pinchas Tsukerman et al.   Oncotarget

hnRNPA2/B1 and nELAV proteins bind to a specific U-rich element in CDK5R1 3′-UTR and oppositely regulate its expression

(2014) Paola Zuccotti et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

MicroRNAs define distinct human neuroblastoma cell phenotypes and regulate their differentiation and tumorigenicity

(2014) Leleesha Samaraweera et al.   BMC CANCER

ALK Mutations Confer Differential Oncogenic Activation and Sensitivity to ALK Inhibition Therapy in Neuroblastoma

(2014) Scott C. Bresler et al.   CANCER CELL

Deep MicroRNA sequencing reveals downregulation of miR-29a in neuroblastoma central nervous system metastasis

(2014) Irene Y. Cheung et al.   GENES CHROMOSOMES & CANCER

miR-372 Regulates Glioma Cell Proliferation and Invasion by Directly Targeting PHLPP2

(2014) Xin Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

MicroRNAs and cancer

(2014) F. L. Kisseljov   MOLECULAR BIOLOGY

miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives

(2014) Andreas Gisel et al.   MOLECULES

MicroRNAs in Neuroblastoma: Small-Sized Players with a Large Impact

(2014) Feng Zhi et al.   NEUROCHEMICAL RESEARCH

miR-335 functions as a tumor suppressor in pancreatic cancer by targeting OCT4

(2014) Ling Gao et al.   TUMOR BIOLOGY

The roles of microRNAs in neuroblastoma

(2014) Hong Mei et al.   World Journal of Pediatrics

Natural Killer Cells and Neuroblastoma: Tumor Recognition, Escape Mechanisms, and Possible Novel Immunotherapeutic Approaches

(2014) Cristina Bottino et al.   Frontiers in Immunology

MicroRNAs in Cancer

(2013) Gianpiero Di Leva et al.   Annual Review of Pathology-Mechanisms of Disease

Molecular aspects of cancer cell resistance to chemotherapy

(2013) Magali Rebucci et al.   BIOCHEMICAL PHARMACOLOGY

At the frontier of progress for paediatric oncology: the neuroblastoma paradigm

(2013) L. Moreno et al.   BRITISH MEDICAL BULLETIN

G-CSF Receptor Positive Neuroblastoma Subpopulations Are Enriched in Chemotherapy-Resistant or Relapsed Tumors and Are Highly Tumorigenic

(2013) Danielle M. Hsu et al.   CANCER RESEARCH

The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease

(2013) E Mogilyansky et al.   CELL DEATH AND DIFFERENTIATION

Symmetric vs. Asymmetric Stem Cell Divisions: An Adaptation against Cancer?

(2013) Leili Shahriyari et al.   PLoS One

miR-335 and miR-363 regulation of neuroblastoma tumorigenesis and metastasis

(2013) Jingbo Qiao et al.   SURGERY

MYCN-mediated transcriptional repression in neuroblastoma: the other side of the coin

(2013) Samuele Gherardi et al.   Frontiers in Oncology

Tumour Hypoxia Affects the Responsiveness of Cancer Cells to Chemotherapy and Promotes Cancer Progression

(2012) Jean-Philippe Cosse et al.   Anti-Cancer Agents in Medicinal Chemistry

Tumour suppressor genes in chemotherapeutic drug response

(2012) Dulcie Lai et al.   BIOSCIENCE REPORTS

MicroRNA-204 increases sensitivity of neuroblastoma cells to cisplatin and is associated with a favourable clinical outcome

(2012) J Ryan et al.   BRITISH JOURNAL OF CANCER

Stromal cells in tumor microenvironment and breast cancer

(2012) Yan Mao et al.   CANCER AND METASTASIS REVIEWS

Cancer stem cells

(2012) Zuoren Yu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Micro-RNA-21 regulates the sensitivity to cisplatin in human neuroblastoma cells

(2012) Yun Chen et al.   JOURNAL OF PEDIATRIC SURGERY

N-myc and Noncoding RNAs in Neuroblastoma

(2012) J. Buechner et al.   MOLECULAR CANCER RESEARCH

microRNA-9 Targets Matrix Metalloproteinase 14 to Inhibit Invasion, Metastasis, and Angiogenesis of Neuroblastoma Cells

(2012) H. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

(2012) Ravid Straussman et al.   NATURE

LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression

(2012) Jan J Molenaar et al.   NATURE GENETICS

Redefining functional MYCN gene signatures in neuroblastoma

(2012) J. M. Shohet   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional MYCN signature predicts outcome of neuroblastoma irrespective of MYCN amplification

(2012) L. J. Valentijn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of let-7 and its target oncogenes (Review)

(2012) XIRUI WANG et al.   Oncology Letters

Cancer drug pan-resistance: pumps, cancer stem cells, quiescence, epithelial to mesenchymal transition, blocked cell death pathways, persisters or what?

(2012) P. Borst   Open Biology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

miR-210: The Master Hypoxamir

(2011) YUK C. CHAN et al.   MICROCIRCULATION

The Role of miR-103 and miR-107 in Regulation of CDK5R1 Expression and in Cellular Migration

(2011) Silvia Moncini et al.   PLoS One

Overexpression of miR-128 specifically inhibits the truncated isoform of NTRK3 and upregulates BCL2 in SH-SY5Y neuroblastoma cells

(2010) Monica Guidi et al.   BMC MOLECULAR BIOLOGY

MicroRNA Mediates DNA Demethylation Events Triggered by Retinoic Acid during Neuroblastoma Cell Differentiation

(2010) S. Das et al.   CANCER RESEARCH

MicroRNA Profiling Reveals Two Distinct p53-Related Human Pluripotent Stem Cell States

(2010) Pierre Neveu et al.   Cell Stem Cell

The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-β Pathway in Neuroblastoma

(2010) Pieter Mestdagh et al.   MOLECULAR CELL

A Link between mir-100 and FRAP1/mTOR in Clear Cell Ovarian Cancer

(2010) Ankur K. Nagaraja et al.   MOLECULAR ENDOCRINOLOGY

miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma

(2010) Alexander Swarbrick et al.   NATURE MEDICINE

Recent Advances in Neuroblastoma

(2010) John M. Maris   NEW ENGLAND JOURNAL OF MEDICINE

MYCN-regulated microRNAs repress estrogen receptor-  (ESR1) expression and neuronal differentiation in human neuroblastoma

(2010) J. Loven et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs in Plasma of Pancreatic Ductal Adenocarcinoma Patients as Novel Blood-Based Biomarkers of Disease

(2009) J. Wang et al.   Cancer Prevention Research

Mutant p53 Drives Invasion by Promoting Integrin Recycling

(2009) Patricia A.J. Muller et al.   CELL

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

MicroRNA Involvement in the Pathogenesis of Neuroblastoma: Potential for MicroRNA Mediated Therapeutics

(2009) R. Stallings   CURRENT PHARMACEUTICAL DESIGN

Anaplastic lymphoma kinase: role in cancer pathogenesis and small-molecule inhibitor development for therapy

(2009) Thomas R Webb et al.   Expert Review of Anticancer Therapy

Role of microRNA in anticancer drug resistance

(2009) Tongsen Zheng et al.   INTERNATIONAL JOURNAL OF CANCER

Apoptosis and cancer: mutations within caspase genes

(2009) S Ghavami et al.   JOURNAL OF MEDICAL GENETICS

MicroRNA-328 Negatively Regulates the Expression of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Cancer Cells

(2009) Y.-Z. Pan et al.   MOLECULAR PHARMACOLOGY

miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche

(2009) Li-Chun Cheng et al.   NATURE NEUROSCIENCE

MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors

(2009) P Mestdagh et al.   ONCOGENE

Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein

(2009) M R Abedini et al.   ONCOGENE

STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells

(2009) Maureen M. Sherry et al.   STEM CELLS

Neuroblastoma: Biology and staging

(2009) Sabine Mueller et al.   Current Oncology Reports

Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells

(2008) Hua Zhu et al.   BIOCHEMICAL PHARMACOLOGY

Effect of tumor suppressor gene PTEN on the resistance to cisplatin in human ovarian cancer cell lines and related mechanisms

(2008) HuiJuan Wu et al.   CANCER LETTERS

Cancer Stem Cells: How can we Target them?

(2008) Ivan Ischenko et al.   CURRENT MEDICINAL CHEMISTRY

The International Neuroblastoma Risk Group (INRG) Staging System: An INRG Task Force Report

(2008) Tom Monclair et al.   JOURNAL OF CLINICAL ONCOLOGY

Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin

(2008) O. Kovalchuk et al.   MOLECULAR CANCER THERAPEUTICS

MicroRNAs modulate the chemosensitivity of tumor cells

(2008) P. E. Blower et al.   MOLECULAR CANCER THERAPEUTICS

Identification of ALK as a major familial neuroblastoma predisposition gene

(2008) Yaël P. Mossé et al.   NATURE

Oncogenic mutations of ALK kinase in neuroblastoma

(2008) Yuyan Chen et al.   NATURE

Antagomir-17-5p Abolishes the Growth of Therapy-Resistant Neuroblastoma through p21 and BIM

(2008) Laura Fontana et al.   PLoS One