A Molecular Hero Suit for In Vitro and In Vivo DNA Nanostructures

Self-Assembled Tetrahedral DNA Nanostructures Promote Neural Stem Cell Proliferation and Neuronal Differentiation

(2018) Wenjuan Ma et al.   ACS Applied Materials & Interfaces

A Telomerase-Responsive DNA Icosahedron for Precise Delivery of Platinum Nanodrugs to Cisplatin-Resistant Cancer

(2018) Yi Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reconfigurable DNA Nanoswitches for Graphical Readout of Molecular Signals

(2018) Arun Richard Chandrasekaran   CHEMBIOCHEM

Intracellular Delivery of Nanomaterials via an Inertial Microfluidic Cell Hydroporator

(2018) Yanxiang Deng et al.   NANO LETTERS

Modulation of the Cellular Uptake of DNA Origami through Control over Mass and Shape

(2018) Maartje M. C. Bastings et al.   NANO LETTERS

Entry, fate and degradation of DNA nanocages in mammalian cells: a matter of receptors

(2018) Sofia Raniolo et al.   Nanoscale

DNA-based construction at the nanoscale: emerging trends and applications

(2018) P Lourdu Xavier et al.   NANOTECHNOLOGY

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

(2018) Suping Li et al.   NATURE BIOTECHNOLOGY

DNA Origami Inside-Out Viruses

(2018) Jonathan R. Burns et al.   ACS Synthetic Biology

Spatiomechanical Modulation of EphB4-Ephrin-B2 Signaling in Neural Stem Cell Differentiation

(2018) Meimei Dong et al.   BIOPHYSICAL JOURNAL

Aptamer-Mediated Delivery of Chemotherapy to Pancreatic Cancer Cells

(2018) Partha Ray et al.   Nucleic Acid Therapeutics

Affinity-Modulated Molecular Beacons on MoS2 Nanosheets for MicroRNA Detection

(2018) Mingshu Xiao et al.   ACS Applied Materials & Interfaces

A pH-correctable, DNA-based fluorescent reporter for organellar calcium

(2018) Nagarjun Narayanaswamy et al.   NATURE METHODS

DNA Nanocarriers: Programmed to Deliver

(2018) Bharath Raj Madhanagopal et al.   TRENDS IN BIOCHEMICAL SCIENCES

DNA origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury

(2018) Dawei Jiang et al.   Nature Biomedical Engineering

Development of DNA Nanostructures for High-Affinity Binding to Human Serum Albumin

(2017) Aurélie Lacroix et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical modifications and reactions in DNA nanostructures

(2017) Kurt V. Gothelf   MRS BULLETIN

One DNA strand homo-polymerizes into defined nanostructures

(2017) Mo Li et al.   Nanoscale

DNA origami/gold nanorod hybrid nanostructures for the circumvention of drug resistance

(2017) Linlin Song et al.   Nanoscale

Triplex-forming oligonucleotides: a third strand for DNA nanotechnology

(2017) Arun Richard Chandrasekaran et al.   NUCLEIC ACIDS RESEARCH

Addressable configurations of DNA nanostructures for rewritable memory

(2017) Arun Richard Chandrasekaran et al.   NUCLEIC ACIDS RESEARCH

Imaging the halogen bond in self-assembled halogenbenzenes on silver

(2017) Zhumin Han et al.   SCIENCE

Oligolysine-based coating protects DNA nanostructures from low-salt denaturation and nuclease degradation

(2017) Nandhini Ponnuswamy et al.   Nature Communications

Design and Characterization of DNA Strand-Displacement Circuits in Serum-Supplemented Cell Medium

(2017) Joshua Fern et al.   ACS Synthetic Biology

Protein Coating of DNA Nanostructures for Enhanced Stability and Immunocompatibility

(2017) Henni Auvinen et al.   Advanced Healthcare Materials

Click-based functionalization of a 2′-O-propargyl-modified branched DNA nanostructure

(2017) Vibhav Valsangkar et al.   Journal of Materials Chemistry B

DNA nanotechnology

(2017) Nadrian C. Seeman et al.   Nature Reviews Materials

“Sense-and-Treat” DNA Nanodevice for Synergetic Destruction of Circulating Tumor Cells

(2016) Nandi Chen et al.   ACS Applied Materials & Interfaces

Multiple-Armed Tetrahedral DNA Nanostructures for Tumor-Targeting, Dual-Modality in Vivo Imaging

(2016) Dawei Jiang et al.   ACS Applied Materials & Interfaces

A Photosensitizer-Loaded DNA Origami Nanosystem for Photodynamic Therapy

(2016) Xiaoxi Zhuang et al.   ACS Nano

Computer-Aided Production of Scaffolded DNA Nanostructures from Flat Sheet Meshes

(2016) Erik Benson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tumor-Penetrating Peptide-Modified DNA Tetrahedron for Targeting Drug Delivery

(2016) Zhiwei Xia et al.   BIOCHEMISTRY

A multifunctional DNA origami as carrier of metal complexes to achieve enhanced tumoral delivery and nullified systemic toxicity

(2016) Yanyu Huang et al.   BIOMATERIALS

Beyond the Fold: Emerging Biological Applications of DNA Origami

(2016) Arun Richard Chandrasekaran et al.   CHEMBIOCHEM

Cellular processing and destinies of artificial DNA nanostructures

(2016) Di Sheng Lee et al.   CHEMICAL SOCIETY REVIEWS

DNA Nanocages

(2016) Arun Richard Chandrasekaran et al.   CHEMISTRY OF MATERIALS

Self-assembled mirror DNA nanostructures for tumor-specific delivery of anticancer drugs

(2016) Kyoung-Ran Kim et al.   JOURNAL OF CONTROLLED RELEASE

Optimized DNA “Nanosuitcases” for Encapsulation and Conditional Release of siRNA

(2016) Katherine E. Bujold et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Light-Triggered Release of Bioactive Molecules from DNA Nanostructures

(2016) Richie E. Kohman et al.   NANO LETTERS

Electrotransfection of Polyamine Folded DNA Origami Structures

(2016) Aradhana Chopra et al.   NANO LETTERS

Programmable DNA scaffolds for spatially-ordered protein assembly

(2016) Arun Richard Chandrasekaran   Nanoscale

Programmable RNA microstructures for coordinated delivery of siRNAs

(2016) Jaimie Marie Stewart et al.   Nanoscale

Thought-Controlled Nanoscale Robots in a Living Host

(2016) Shachar Arnon et al.   PLoS One

Nucleic Acid Nanostructures for Chemical and Biological Sensing

(2016) Arun Richard Chandrasekaran et al.   Small

DNA Nanostructures Carrying Stoichiometrically Definable Antibodies

(2016) Magdiel Inggrid Setyawati et al.   Small

Intracellular Delivery of a Planar DNA Origami Structure by the Transferrin-Receptor Internalization Pathway

(2016) David H. Schaffert et al.   Small

Single-molecule observations of RNA–RNA kissing interactions in a DNA nanostructure

(2016) Yosuke Takeuchi et al.   Biomaterials Science

Uncovering the forces between nucleosomes using DNA origami

(2016) J. J. Funke et al.   Science Advances

Self-Assembled DNA Immunonanoflowers as Multivalent CpG Nanoagents

(2015) Liqin Zhang et al.   ACS Applied Materials & Interfaces

One-Step Formation of “Chain-Armor”-Stabilized DNA Nanostructures

(2015) Valentina Cassinelli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Growth and Origami Folding of DNA on Nanoparticles for High-Efficiency Molecular Transport in Cellular Imaging and Drug Delivery

(2015) Juan Yan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNA nanotubes as intracellular delivery vehicles in vivo

(2015) Sabine Sellner et al.   BIOMATERIALS

DNA origami and biotechnology applications: a perspective

(2015) Arun Richard Chandrasekaran   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Self-Assembly of Responsive Multilayered DNA Nanocages

(2015) Zhiyu Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA topology influences molecular machine lifetime in human serum

(2015) Sara Goltry et al.   Nanoscale

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

A pH-independent DNA nanodevice for quantifying chloride transport in organelles of living cells

(2015) Sonali Saha et al.   Nature Nanotechnology

Complex wireframe DNA origami nanostructures with multi-arm junction vertices

(2015) Fei Zhang et al.   Nature Nanotechnology

Designing DNA nanodevices for compatibility with the immune system of higher organisms

(2015) Sunaina Surana et al.   Nature Nanotechnology

Programmable materials and the nature of the DNA bond

(2015) M. R. Jones et al.   SCIENCE

A Self-Assembled DNA Origami-Gold Nanorod Complex for Cancer Theranostics

(2015) Qiao Jiang et al.   Small

Daunorubicin-Loaded DNA Origami Nanostructures Circumvent Drug-Resistance Mechanisms in a Leukemia Model

(2015) Patrick D. Halley et al.   Small

A DNA-based system for selecting and displaying the combined result of two input variables

(2015) Huajie Liu et al.   Nature Communications

Programmable DNA Nanoswitches for Detection of Nucleic Acid Sequences

(2015) Arun Richard Chandrasekaran et al.   ACS Sensors

DNA Origami as an In Vivo Drug Delivery Vehicle for Cancer Therapy

(2014) Qian Zhang et al.   ACS Nano

Virus-Inspired Membrane Encapsulation of DNA Nanostructures To Achieve In Vivo Stability

(2014) Steven D. Perrault et al.   ACS Nano

Addressing the Instability of DNA Nanostructures in Tissue Culture

(2014) Jaeseung Hahn et al.   ACS Nano

DNA Nanoflowers for Multiplexed Cellular Imaging and Traceable Targeted Drug Delivery

(2014) Rong Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Single-Particle Tracking and Modulation of Cell Entry Pathways of a Tetrahedral DNA Nanostructure in Live Cells

(2014) Le Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural DNA Nanotechnology: State of the Art and Future Perspective

(2014) Fei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bioactive DNA-Peptide Nanotubes Enhance the Differentiation of Neural Stem Cells Into Neurons

(2014) Nicholas Stephanopoulos et al.   NANO LETTERS

Virus-Encapsulated DNA Origami Nanostructures for Cellular Delivery

(2014) Joona Mikkilä et al.   NANO LETTERS

Toward Larger DNA Origami

(2014) Alexandria N. Marchi et al.   NANO LETTERS

Polyhedra Self-Assembled from DNA Tripods and Characterized with 3D DNA-PAINT

(2014) R. Iinuma et al.   SCIENCE

Sequence-responsive unzipping DNA cubes with tunable cellular uptake profiles

(2014) Katherine E. Bujold et al.   Chemical Science

Cellular Uptake of Tile-Assembled DNA Nanotubes

(2014) Samet Kocabey et al.   Nanomaterials

Nuclease-Resistant DNA via High-Density Packing in Polymeric Micellar Nanoparticle Coronas

(2013) Anthony M. Rush et al.   ACS Nano

Temperature-Controlled Encapsulation and Release of an Active Enzyme in the Cavity of a Self-Assembled DNA Nanocage

(2013) Sissel Juul et al.   ACS Nano

Development and Characterization of Gene Silencing DNA Cages

(2013) Johans J. Fakhoury et al.   BIOMACROMOLECULES

A Smart DNA Tetrahedron That Isothermally Assembles or Dissociates in Response to the Solution pH Value Changes

(2013) Zhiyu Liu et al.   BIOMACROMOLECULES

Self-assembly of DNA nanoprisms with only two component strands

(2013) Zhou Nie et al.   CHEMICAL COMMUNICATIONS

Drug delivery by a self-assembled DNA tetrahedron for overcoming drug resistance in breast cancer cells

(2013) Kyoung-Ran Kim et al.   CHEMICAL COMMUNICATIONS

Noncanonical Self-Assembly of Multifunctional DNA Nanoflowers for Biomedical Applications

(2013) Guizhi Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics

(2013) G. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G-quadruplex-binding ligand-induced DNA synapsis inside a DNA origami frame

(2013) Arivazhagan Rajendran et al.   RSC Advances

DNA Origami Delivery System for Cancer Therapy with Tunable Release Properties

(2012) Yong-Xing Zhao et al.   ACS Nano

A New Modular Approach to Nanoassembly: Stable and Addressable DNA Nanoconstructs via Orthogonal Click Chemistries

(2012) Simon R. Gerrard et al.   ACS Nano

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

Visualization of the intracellular location and stability of DNA origami with a label-free fluorescent probe

(2012) Xibo Shen et al.   CHEMICAL COMMUNICATIONS

DNA nanostructure serum stability: greater than the sum of its parts

(2012) Justin W. Conway et al.   CHEMICAL COMMUNICATIONS

Interenzyme Substrate Diffusion for an Enzyme Cascade Organized on Spatially Addressable DNA Nanostructures

(2012) Jinglin Fu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA Origami as a Carrier for Circumvention of Drug Resistance

(2012) Qiao Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rolling Circle Amplification-Templated DNA Nanotubes Show Increased Stability and Cell Penetration Ability

(2012) Graham D. Hamblin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single-Step Rapid Assembly of DNA Origami Nanostructures for Addressable Nanoscale Bioreactors

(2012) Yanming Fu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reversibly Switching the Surface Porosity of a DNA Tetrahedron

(2012) Chuan Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A DNA Nanostructure Platform for Directed Assembly of Synthetic Vaccines

(2012) Xiaowei Liu et al.   NANO LETTERS

Complex shapes self-assembled from single-stranded DNA tiles

(2012) Bryan Wei et al.   NATURE

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

Three-Dimensional Structures Self-Assembled from DNA Bricks

(2012) Y. Ke et al.   SCIENCE

A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads

(2012) S. M. Douglas et al.   SCIENCE

Cellular Immunostimulation by CpG-Sequence-Coated DNA Origami Structures

(2011) Verena J. Schüller et al.   ACS Nano

Aptamer-Conjugated DNA Icosahedral Nanoparticles As a Carrier of Doxorubicin for Cancer Therapy

(2011) Microsugar Chang et al.   ACS Nano

Self-Assembled Multivalent DNA Nanostructures for Noninvasive Intracellular Delivery of Immunostimulatory CpG Oligonucleotides

(2011) Jiang Li et al.   ACS Nano

Exploring the Role of Chirality in Nucleic Acid Recognition

(2011) Daniele D'Alonzo et al.   CHEMISTRY & BIODIVERSITY

Polyvalent Nucleic Acid Nanostructures

(2011) Joshua I. Cutler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photo-Cross-Linking-Assisted Thermal Stability of DNA Origami Structures and Its Application for Higher-Temperature Self-Assembly

(2011) Arivazhagan Rajendran et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stability of DNA Origami Nanoarrays in Cell Lysate

(2011) Qian Mei et al.   NANO LETTERS

A primer to scaffolded DNA origami

(2011) Carlos Ernesto Castro et al.   NATURE METHODS

Thermodynamically stable RNA three-way junction for constructing multifunctional nanoparticles for delivery of therapeutics

(2011) Dan Shu et al.   Nature Nanotechnology

Scaling Up Digital Circuit Computation with DNA Strand Displacement Cascades

(2011) L. Qian et al.   SCIENCE

DNA Origami with Complex Curvatures in Three-Dimensional Space

(2011) D. Han et al.   SCIENCE

A synthetic icosahedral DNA-based host–cargo complex for functional in vivo imaging

(2011) Dhiraj Bhatia et al.   Nature Communications

An autonomous DNA nanomachine maps spatiotemporal pH changes in a multicellular living organism

(2011) Sunaina Surana et al.   Nature Communications

A Versatile DNA Nanochip for Direct Analysis of DNA Base-Excision Repair

(2010) Masayuki Endo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular robots guided by prescriptive landscapes

(2010) Kyle Lund et al.   NATURE

Loading and selective release of cargo in DNA nanotubes with longitudinal variation

(2010) Pik Kwan Lo et al.   Nature Chemistry

Enhanced resistance of DNA nanostructures to enzymatic digestion

(2009) Jung-Won Keum et al.   CHEMICAL COMMUNICATIONS

Multilayer DNA Origami Packed on a Square Lattice

(2009) Yonggang Ke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enzyme cascades activated on topologically programmed DNA scaffolds

(2009) Ofer I. Wilner et al.   Nature Nanotechnology

Folding DNA into Twisted and Curved Nanoscale Shapes

(2009) H. Dietz et al.   SCIENCE

DNA Nanotubes as Combinatorial Vehicles for Cellular Delivery

(2008) SeungHyeon Ko et al.   BIOMACROMOLECULES

Nonviral Vectors for Gene Delivery

(2008) Meredith A. Mintzer et al.   CHEMICAL REVIEWS