Daunorubicin-Loaded DNA Origami Nanostructures Circumvent Drug-Resistance Mechanisms in a Leukemia Model

Nanotechnologies in Cancer Treatment and Diagnosis

(2017) Stephanie A. Morris et al.   Journal of the National Comprehensive Cancer Network

Inhibition of Multidrug Resistance of Cancer Cells by Co-Delivery of DNA Nanostructures and Drugs Using Porous Silicon Nanoparticles@Giant Liposomes

(2015) Feng Kong et al.   ADVANCED FUNCTIONAL MATERIALS

DNA Origami as an In Vivo Drug Delivery Vehicle for Cancer Therapy

(2014) Qian Zhang et al.   ACS Nano

Virus-Inspired Membrane Encapsulation of DNA Nanostructures To Achieve In Vivo Stability

(2014) Steven D. Perrault et al.   ACS Nano

Addressing the Instability of DNA Nanostructures in Tissue Culture

(2014) Jaeseung Hahn et al.   ACS Nano

Facile and Scalable Preparation of Pure and Dense DNA Origami Solutions

(2014) Evi Stahl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phase 2 trial of CPX-351, a fixed 5:1 molar ratio of cytarabine/daunorubicin, vs cytarabine/daunorubicin in older adults with untreated AML

(2014) J. E. Lancet et al.   BLOOD

Quantification of cellular uptake of DNA nanostructures by qPCR

(2014) Anders Hauge Okholm et al.   METHODS

Spatial control of membrane receptor function using ligand nanocalipers

(2014) Alan Shaw et al.   NATURE METHODS

Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT

(2014) Ralf Jungmann et al.   NATURE METHODS

Engineered nanoparticles interacting with cells: size matters

(2014) Li Shang et al.   JOURNAL OF NANOBIOTECHNOLOGY

DNA Origami Compliant Nanostructures with Tunable Mechanical Properties

(2013) Lifeng Zhou et al.   ACS Nano

Controlled Release of Encapsulated Cargo from a DNA Icosahedron using a Chemical Trigger

(2013) Anusuya Banerjee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanooncology: The future of cancer diagnosis and therapy

(2013) Avnesh S. Thakor et al.   CA-A CANCER JOURNAL FOR CLINICIANS

RNA-templated DNA origami structures

(2013) Masayuki Endo et al.   CHEMICAL COMMUNICATIONS

The enabled state of DNA nanotechnology

(2013) Veikko Linko et al.   CURRENT OPINION IN BIOTECHNOLOGY

Comparative Assessment of Clinically Utilized CD20-Directed Antibodies in Chronic Lymphocytic Leukemia Cells Reveals Divergent NK Cell, Monocyte, and Macrophage Properties

(2013) S. Rafiq et al.   JOURNAL OF IMMUNOLOGY

Emerging Research and Clinical Development Trends of Liposome and Lipid Nanoparticle Drug Delivery Systems

(2013) John C. Kraft et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Enhanced tumor delivery and antitumor activity in vivo of liposomal doxorubicin modified with MCF-7-specific phage fusion protein

(2013) Tao Wang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Hierarchical assembly of metal nanoparticles, quantum dots and organic dyes using DNA origami scaffolds

(2013) Robert Schreiber et al.   Nature Nanotechnology

Two DNA nanomachines map pH changes along intersecting endocytic pathways inside the same cell

(2013) Souvik Modi et al.   Nature Nanotechnology

DNA Origami Delivery System for Cancer Therapy with Tunable Release Properties

(2012) Yong-Xing Zhao et al.   ACS Nano

Population pharmacokinetics of cytarabine, etoposide, and daunorubicin in the treatment for acute myeloid leukemia

(2012) Mikkel Krogh-Madsen et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Overcoming Limitations in Nanoparticle Drug Delivery: Triggered, Intravascular Release to Improve Drug Penetration into Tumors

(2012) A. A. Manzoor et al.   CANCER RESEARCH

Multistep Drug Intercalation: Molecular Dynamics and Free Energy Studies of the Binding of Daunomycin to DNA

(2012) Matthieu Wilhelm et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA Origami as a Carrier for Circumvention of Drug Resistance

(2012) Qiao Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

Rapid Folding of DNA into Nanoscale Shapes at Constant Temperature

(2012) J.-P. J. Sobczak et al.   SCIENCE

A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads

(2012) S. M. Douglas et al.   SCIENCE

Cellular Immunostimulation by CpG-Sequence-Coated DNA Origami Structures

(2011) Verena J. Schüller et al.   ACS Nano

Aptamer-Conjugated DNA Icosahedral Nanoparticles As a Carrier of Doxorubicin for Cancer Therapy

(2011) Microsugar Chang et al.   ACS Nano

Self-Assembled Multivalent DNA Nanostructures for Noninvasive Intracellular Delivery of Immunostimulatory CpG Oligonucleotides

(2011) Jiang Li et al.   ACS Nano

Nanoparticle Delivery of Cancer Drugs

(2011) Andrew Z. Wang et al.   Annual Review of Medicine

Phase I Trial of Lenalidomide and CCI-779 in Patients With Relapsed Multiple Myeloma: Evidence for Lenalidomide–CCI-779 Interaction via P-Glycoprotein

(2011) Craig C. Hofmeister et al.   JOURNAL OF CLINICAL ONCOLOGY

Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake

(2011) Carl D. Walkey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A primer to scaffolded DNA origami

(2011) Carlos Ernesto Castro et al.   NATURE METHODS

DNA Origami-Templated Growth of Arbitrarily Shaped Metal Nanoparticles

(2011) Robert Schreiber et al.   Small

Orthogonal Protein Decoration of DNA Origami

(2010) Barbara Saccà et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reversal of multidrug resistance by magnetic Fe3O4 nanoparticle copolymerizating daunorubicin and MDR1 shRNA expression vector in leukemia cells

(2010) Baoan Chen   International Journal of Nanomedicine

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Multilayer DNA Origami Packed on a Square Lattice

(2009) Yonggang Ke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-assembly of DNA into nanoscale three-dimensional shapes

(2009) Shawn M. Douglas et al.   NATURE

Multifunctional nanoarchitectures from DNA-based ABC monomers

(2009) Jong B. Lee et al.   Nature Nanotechnology

A DNA nanomachine that maps spatial and temporal pH changes inside living cells

(2009) Souvik Modi et al.   Nature Nanotechnology

An Old AML Drug Revisited

(2009) Hervé Dombret et al.   NEW ENGLAND JOURNAL OF MEDICINE

High-Dose Daunorubicin in Older Patients with Acute Myeloid Leukemia

(2009) Bob Löwenberg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rapid prototyping of 3D DNA-origami shapes with caDNAno

(2009) Shawn M. Douglas et al.   NUCLEIC ACIDS RESEARCH

Nanoparticle therapeutics: an emerging treatment modality for cancer

(2008) Mark E. Davis et al.   NATURE REVIEWS DRUG DISCOVERY

Nanotechnology and Cancer

(2007) James R. Heath et al.   Annual Review of Medicine