DNA origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury

DNA Nanotechnology-Enabled Drug Delivery Systems

(2018) Qinqin Hu et al.   CHEMICAL REVIEWS

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

(2018) Suping Li et al.   NATURE BIOTECHNOLOGY

Biotechnological mass production of DNA origami

(2017) Florian Praetorius et al.   NATURE

Engineering nucleic acid structures for programmable molecular circuitry and intracellular biocomputation

(2017) Jiang Li et al.   Nature Chemistry

Glomerular barrier behaves as an atomically precise bandpass filter in a sub-nanometre regime

(2017) Bujie Du et al.   Nature Nanotechnology

Oligolysine-based coating protects DNA nanostructures from low-salt denaturation and nuclease degradation

(2017) Nandhini Ponnuswamy et al.   Nature Communications

Multiple-Armed Tetrahedral DNA Nanostructures for Tumor-Targeting, Dual-Modality in Vivo Imaging

(2016) Dawei Jiang et al.   ACS Applied Materials & Interfaces

DNA-Nanostructure-Gold-Nanorod Hybrids for Enhanced In Vivo Optoacoustic Imaging and Photothermal Therapy

(2016) Yang Du et al.   ADVANCED MATERIALS

A porphyrin-PEG polymer with rapid renal clearance

(2016) Haoyuan Huang et al.   BIOMATERIALS

DNA nanomaterials for preclinical imaging and drug delivery

(2016) Dawei Jiang et al.   JOURNAL OF CONTROLLED RELEASE

Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice

(2016) Satoko Arai et al.   NATURE MEDICINE

Nanomedicines for renal disease: current status and future applications

(2016) Nazila Kamaly et al.   Nature Reviews Nephrology

Hetero-assembly of gold nanoparticles on a DNA origami template

(2016) Jie Chao et al.   Science China-Chemistry

Targeted fibrillar nanocarbon RNAi treatment of acute kidney injury

(2016) Simone Alidori et al.   Science Translational Medicine

Gallium-68 EDTA PET/CT for Renal Imaging

(2016) Michael S. Hofman et al.   SEMINARS IN NUCLEAR MEDICINE

Genetic encoding of DNA nanostructures and their self-assembly in living bacteria

(2016) Johann Elbaz et al.   Nature Communications

Soft Discoidal Polymeric Nanoconstructs Resist Macrophage Uptake and Enhance Vascular Targeting in Tumors

(2015) Jaehong Key et al.   ACS Nano

Clinical Translation of Nanomedicine

(2015) Yuanzeng Min et al.   CHEMICAL REVIEWS

68Ga-EDTA PET/CT Imaging and Plasma Clearance for Glomerular Filtration Rate Quantification: Comparison to Conventional 51Cr-EDTA

(2015) M. Hofman et al.   JOURNAL OF NUCLEAR MEDICINE

Mesoscale Nanoparticles Selectively Target the Renal Proximal Tubule Epithelium

(2015) Ryan M. Williams et al.   NANO LETTERS

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Complex wireframe DNA origami nanostructures with multi-arm junction vertices

(2015) Fei Zhang et al.   Nature Nanotechnology

Designing DNA nanodevices for compatibility with the immune system of higher organisms

(2015) Sunaina Surana et al.   Nature Nanotechnology

DNA nanotechnology from the test tube to the cell

(2015) Yuan-Jyue Chen et al.   Nature Nanotechnology

Cerium oxide nanoparticles attenuate acute kidney injury induced by intra-abdominal infection in Sprague–Dawley rats

(2015) Nandini D. P. K. Manne et al.   JOURNAL OF NANOBIOTECHNOLOGY

Singlet Oxygen in DNA Nanotechnology

(2014) Thomas Tørring et al.   ACCOUNTS OF CHEMICAL RESEARCH

DNA Origami as an In Vivo Drug Delivery Vehicle for Cancer Therapy

(2014) Qian Zhang et al.   ACS Nano

Addressing the Instability of DNA Nanostructures in Tissue Culture

(2014) Jaeseung Hahn et al.   ACS Nano

Programmable Engineering of a Biosensing Interface with Tetrahedral DNA Nanostructures for Ultrasensitive DNA Detection

(2014) Meihua Lin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cocoon-Like Self-Degradable DNA Nanoclew for Anticancer Drug Delivery

(2014) Wujin Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Acute Kidney Injury and Chronic Kidney Disease as Interconnected Syndromes

(2014) Lakhmir S. Chawla et al.   NEW ENGLAND JOURNAL OF MEDICINE

Animal models of acute renal failure

(2014) Amrit Pal Singh et al.   Pharmacological Reports

Raising awareness of acute kidney injury: a global perspective of a silent killer

(2013) Andrew J.P. Lewington et al.   KIDNEY INTERNATIONAL

Comparative genomics of defense systems in archaea and bacteria

(2013) Kira S. Makarova et al.   NUCLEIC ACIDS RESEARCH

Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics

(2013) G. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA Base Damage by Reactive Oxygen Species, Oxidizing Agents, and UV Radiation

(2013) J. Cadet et al.   Cold Spring Harbor Perspectives in Biology

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

Interenzyme Substrate Diffusion for an Enzyme Cascade Organized on Spatially Addressable DNA Nanostructures

(2012) Jinglin Fu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Acute kidney injury

(2012) Rinaldo Bellomo et al.   LANCET

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

Self-Assembled Multivalent DNA Nanostructures for Noninvasive Intracellular Delivery of Immunostimulatory CpG Oligonucleotides

(2011) Jiang Li et al.   ACS Nano

Controlling Assembly of Paired Gold Clusters within Apoferritin Nanoreactor for in Vivo Kidney Targeting and Biomedical Imaging

(2011) Cuiji Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stability of DNA Origami Nanoarrays in Cell Lysate

(2011) Qian Mei et al.   NANO LETTERS

Challenges and opportunities for structural DNA nanotechnology

(2011) Andre V. Pinheiro et al.   Nature Nanotechnology

Targeting kidney mesangium by nanoparticles of defined size

(2011) C. H. J. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanomaterials Based on DNA

(2010) Nadrian C. Seeman   Annual Review of Biochemistry

Paradoxical glomerular filtration of carbon nanotubes

(2010) A. Ruggiero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acetaminophen inhibits hemoprotein-catalyzed lipid peroxidation and attenuates rhabdomyolysis-induced renal failure

(2010) O. Boutaud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced resistance of DNA nanostructures to enzymatic digestion

(2009) Jung-Won Keum et al.   CHEMICAL COMMUNICATIONS

Mechanism of Scavenging Action ofN-Acetylcysteine for the OH Radical: A Quantum Computational Study

(2009) Neha Agnihotri et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

(2008) Frank Alexis et al.   MOLECULAR PHARMACEUTICS

N-Acetylcysteine in the Prevention of Contrast-Induced Nephropathy

(2007) S. Fishbane   Clinical Journal of the American Society of Nephrology