The Cross-Talk Between the TNF-α and RASSF-Hippo Signalling Pathways

YAP and TAZ Heterogeneity in Primary Liver Cancer: An Analysis of Its Prognostic and Diagnostic Role

(2019) Matthias Van Haele et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Apoptosis and Clearance of Apoptotic Cells

(2018) Shigekazu Nagata   Annual Review of Immunology

Yes-Associated Protein Promotes Angiogenesis via Signal Transducer and Activator of Transcription 3 in Endothelial CellsNovelty and Significance

(2018) Jinlong He et al.   CIRCULATION RESEARCH

YAP and TAZ are essential for basal and squamous cell carcinoma initiation

(2018) Maud Debaugnies et al.   EMBO REPORTS

Linking Extracellular Matrix Agrin to the Hippo Pathway in Liver Cancer and Beyond

(2018) Sayan Chakraborty et al.   Cancers

The Hippo Signaling Network and its Biological Functions

(2018) Jyoti R. Misra et al.   Annual Review of Genetics

The Hippo pathway in the heart: pivotal roles in development, disease, and regeneration

(2018) Jun Wang et al.   Nature Reviews Cardiology

Tumor Necrosis Factor Receptor-Associated Factor Regulation of Nuclear Factor κB and Mitogen-Activated Protein Kinase Pathways

(2018) Jian-Hong Shi et al.   Frontiers in Immunology

TNF-α-Induced YAP/TAZ Activity Mediates Leukocyte-Endothelial Adhesion by Regulating VCAM1 Expression in Endothelial Cells

(2018) Hyun-Jung Choi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cell type-dependent function of LATS1/2 in cancer cell growth

(2018) Wei-Wei Pan et al.   ONCOGENE

TNFα promotes glioblastoma A172 cell mitochondrial apoptosis via augmenting mitochondrial fission and repression of MAPK–ERK–YAP signaling pathways

(2018) Changyu Lu et al.   OncoTargets and Therapy

Reciprocal inhibition of YAP/TAZ and NF-κB regulates osteoarthritic cartilage degradation

(2018) Yujie Deng et al.   Nature Communications

Hippo Signaling in the Liver Regulates Organ Size, Cell Fate, and Carcinogenesis

(2017) Sachin H. Patel et al.   GASTROENTEROLOGY

YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation

(2017) Jongshin Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Hippo pathway deficiency reverses systolic heart failure after infarction

(2017) John P. Leach et al.   NATURE

The extracellular matrix protein agrin promotes heart regeneration in mice

(2017) Elad Bassat et al.   NATURE

TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration

(2017) Y Gao et al.   Oncogenesis

TRAF2 multitasking in TNF receptor-induced signaling to NF-κB, MAP kinases and cell death

(2016) Alice Borghi et al.   BIOCHEMICAL PHARMACOLOGY

The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity

(2016) Toshiro Moroishi et al.   CELL

Ras signaling through RASSF proteins

(2016) Howard Donninger et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Programmed Cell Death in Neurodevelopment

(2015) Yoshifumi Yamaguchi et al.   DEVELOPMENTAL CELL

Expression of LATS family proteins in ovarian tumors and its significance

(2015) Bing Xu et al.   HUMAN PATHOLOGY

MST kinases in development and disease

(2015) Barry J. Thompson et al.   JOURNAL OF CELL BIOLOGY

LATS2 induced by TNF-alpha and inhibited cell proliferation and invasion by phosphorylating YAP in oral squamous cell carcinoma

(2015) Cong Dong et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

TNF biology, pathogenic mechanisms and emerging therapeutic strategies

(2015) George D. Kalliolias et al.   Nature Reviews Rheumatology

The tumour suppressor Ras-association domain family protein 1A (RASSF1A) regulates TNF-α signalling in cardiomyocytes

(2014) Tamer M.A. Mohamed et al.   CARDIOVASCULAR RESEARCH

Cardiac-Specific YAP Activation Improves Cardiac Function and Survival in an Experimental Murine MI Model

(2014) Zhiqiang Lin et al.   CIRCULATION RESEARCH

TNF and TNF-receptors: From mediators of cell death and inflammation to therapeutic giants – past, present and future

(2014) Lisa M. Sedger et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Inhibition of RHO–ROCK signaling enhances ICM and suppresses TE characteristics through activation of Hippo signaling in the mouse blastocyst

(2014) Kanako Kono et al.   DEVELOPMENTAL BIOLOGY

RASSF tumor suppressor gene family: Biological functions and regulation

(2014) Natalia Volodko et al.   FEBS LETTERS

Hippo activation through homodimerization and membrane association for growth inhibition and organ size control

(2013) Yaoting Deng et al.   DEVELOPMENTAL BIOLOGY

The Hippo pathway: regulators and regulations

(2013) F.-X. Yu et al.   GENES & DEVELOPMENT

The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

(2013) Randy Johnson et al.   NATURE REVIEWS DRUG DISCOVERY

The Tumor Suppressor Gene, RASSF1A, Is Essential for Protection against Inflammation -Induced Injury

(2013) Marilyn Gordon et al.   PLoS One

Mammalian Sterile 20-like Kinase 1 Suppresses Lymphoma Development by Promoting Faithful Chromosome Segregation

(2012) T.-S. Kim et al.   CANCER RESEARCH

The RASSF3 Candidate Tumor Suppressor Induces Apoptosis and G1-S Cell-Cycle Arrest via p53

(2012) T. Kudo et al.   CANCER RESEARCH

Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

(2012) Fa-Xing Yu et al.   CELL

LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap

(2012) H B Nguyen et al.   ONCOGENE

Tao-1 Phosphorylates Hippo/MST Kinases to Regulate the Hippo-Salvador-Warts Tumor Suppressor Pathway

(2011) Julian C. Boggiano et al.   DEVELOPMENTAL CELL

Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein

(2011) B. Zhao et al.   GENES & DEVELOPMENT

NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway

(2011) Sandra Habbig et al.   JOURNAL OF CELL BIOLOGY

Apoptosis in cancer: from pathogenesis to treatment

(2011) Rebecca SY Wong   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Opposing roles of angiomotin-like-1 and zona occludens-2 on pro-apoptotic function of YAP

(2011) T Oka et al.   ONCOGENE

Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance

(2011) D. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components

(2011) N.-G. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apoptosis and autoimmune diseases

(2010) Shigekazu Nagata   Annals of the New York Academy of Sciences

Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling

(2010) Tsutomu Oka et al.   BIOCHEMICAL JOURNAL

Ajuba LIM Proteins Are Negative Regulators of the Hippo Signaling Pathway

(2010) Meghna Das Thakur et al.   CURRENT BIOLOGY

TAZ interacts with zonula occludens-1 and -2 proteins in a PDZ-1 dependent manner

(2010) Eline Remue et al.   FEBS LETTERS

Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in mice

(2010) Dominic P. Del Re et al.   JOURNAL OF CLINICAL INVESTIGATION

The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-κB signaling pathways

(2010) F E Lock et al.   ONCOGENE

Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

(2010) L. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The RASSF proteins in cancer; from epigenetic silencing to functional characterization

(2009) Antje M. Richter et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Tumor Suppressor Ras-Association Domain Family 1 Isoform A Is a Novel Regulator of Cardiac Hypertrophy

(2009) Delvac Oceandy et al.   CIRCULATION

Hippo Pathway-Dependent and -Independent Roles of RASSF6

(2009) M. Ikeda et al.   Science Signaling

Dynamics of RASSF1A/MOAP-1 Association with Death Receptors

(2008) C. J. Foley et al.   MOLECULAR AND CELLULAR BIOLOGY