The Tumor Suppressor Gene, RASSF1A, Is Essential for Protection against Inflammation -Induced Injury

Inflammatory Bowel Disease: Mechanisms, Redox Considerations, and Therapeutic Targets

(2013) Fiorella Biasi et al.   ANTIOXIDANTS & REDOX SIGNALING

p53 Mediates TNF-Induced Epithelial Cell Apoptosis in IBD

(2012) Tatiana Goretsky et al.   AMERICAN JOURNAL OF PATHOLOGY

The activation mechanism of ACK1 (activated Cdc42-associated tyrosine kinase 1)

(2012) Qiong Lin et al.   BIOCHEMICAL JOURNAL

Loss of Rassf1a Synergizes with Deregulated Runx2 Signaling in Tumorigenesis

(2012) L. van der Weyden et al.   CANCER RESEARCH

YAP oncogene overexpression supercharges colon cancer proliferation

(2012) Joseph Avruch et al.   CELL CYCLE

Ablation of Rassf2 induces bone defects and subsequent haematopoietic anomalies in mice

(2012) Hoogeun Song et al.   EMBO JOURNAL

Methylation of RASSF1A gene promoter is regulated by p53 and DAXX

(2012) Hailong Zhang et al.   FASEB JOURNAL

Colorectal cancer and RASSF family-A special emphasis on RASSF1A

(2012) Maria Sofia Fernandes et al.   INTERNATIONAL JOURNAL OF CANCER

Molecular pathways in colorectal cancer

(2012) Sam Al-Sohaily et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

YAP accelerates Aβ25–35-induced apoptosis through upregulation of Bax expression by interaction with p73

(2011) Heng Zhang et al.   APOPTOSIS

Yap1 Acts Downstream of α-Catenin to Control Epidermal Proliferation

(2011) Karin Schlegelmilch et al.   CELL

YAP: At the crossroad between transformation and tumor suppression

(2011) Efrem Bertini et al.   CELL CYCLE

TNFR1-induced activation of the classical NF-κB pathway

(2011) Harald Wajant et al.   FEBS Journal

p53 and PUMA Independently Regulate Apoptosis of Intestinal Epithelial Cells in Patients and Mice With Colitis

(2011) Ramanarao Dirisina et al.   GASTROENTEROLOGY

The Tumor Suppressor RASSF1A Prevents Dephosphorylation of the Mammalian STE20-like Kinases MST1 and MST2

(2011) Cai Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of mouse embryonic stem cell self-renewal by a Yes-YAP-TEAD2 signaling pathway downstream of LIF

(2011) C. Tamm et al.   JOURNAL OF CELL SCIENCE

Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis

(2011) H Nikki March et al.   NATURE GENETICS

Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance

(2011) D. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial repair mechanisms in the lung

(2010) Lynn M. Crosby et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Mst1/2 signalling to Yap: gatekeeper for liver size and tumour development

(2010) J Avruch et al.   BRITISH JOURNAL OF CANCER

Hyaluronic acid and intestinal inflammation

(2010) William F Stenson   CURRENT OPINION IN GASTROENTEROLOGY

Hippo signaling: growth control and beyond

(2010) G. Halder et al.   DEVELOPMENT

The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program

(2010) J. Cai et al.   GENES & DEVELOPMENT

Tumor Suppressor Ras Association Domain Family 5 (RASSF5/NORE1) Mediates Death Receptor Ligand-induced Apoptosis

(2010) Jikyoung Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Upregulation of DNA Methyltransferase-Mediated Gene Silencing, Anchorage-Independent Growth, and Migration of Colon Cancer Cells by Interleukin-6

(2010) E. Foran et al.   MOLECULAR CANCER RESEARCH

Hypoxia: an alarm signal during intestinal inflammation

(2010) Sean P. Colgan et al.   Nature Reviews Gastroenterology & Hepatology

Loss of Rassf1a enhances p53-mediated tumor predisposition and accelerates progression to aneuploidy

(2010) S Tommasi et al.   ONCOGENE

The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-κB signaling pathways

(2010) F E Lock et al.   ONCOGENE

Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways

(2010) F. Ren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial Tight Junctions in Intestinal Inflammation

(2009) Joerg D. Schulzke et al.   Annals of the New York Academy of Sciences

Regulation of Colonic Epithelial Repair in Mice by Toll-Like Receptors and Hyaluronic Acid

(2009) Ling Zheng et al.   GASTROENTEROLOGY

Mer tyrosine kinase (MerTK) promotes macrophage survival following exposure to oxidative stress

(2009) Adil Anwar et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The trefoil factor family – small peptides with multiple functionalities

(2008) S. Kjellev   CELLULAR AND MOLECULAR LIFE SCIENCES

Hypermethylation of RAS effector related genes and DNA methyltransferase 1 expression in endometrial carcinogenesis

(2008) Xiaoyun Liao et al.   INTERNATIONAL JOURNAL OF CANCER

NF-κB in inflammatory bowel disease

(2008) I. Atreya et al.   JOURNAL OF INTERNAL MEDICINE

Dynamics of RASSF1A/MOAP-1 Association with Death Receptors

(2008) C. J. Foley et al.   MOLECULAR AND CELLULAR BIOLOGY

Yap1 Phosphorylation by c-Abl Is a Critical Step in Selective Activation of Proapoptotic Genes in Response to DNA Damage

(2008) Dan Levy et al.   MOLECULAR CELL

Potential of resveratrol in anticancer and anti-inflammatory therapy

(2008) Chibuike C Udenigwe et al.   NUTRITION REVIEWS

Loss of Rassf1a cooperates with Apc Min to accelerate intestinal tumourigenesis

(2008) L van der Weyden et al.   ONCOGENE

Oxidative stress in ulcerative colitis-associated carcinogenesis

(2008) A. Roessner et al.   PATHOLOGY RESEARCH AND PRACTICE

Epithelial restitution and wound healing in inflammatory bowel disease

(2008) Andreas Sturm et al.   WORLD JOURNAL OF GASTROENTEROLOGY