Linking Extracellular Matrix Agrin to the Hippo Pathway in Liver Cancer and Beyond
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Title
Linking Extracellular Matrix Agrin to the Hippo Pathway in Liver Cancer and Beyond
Authors
Keywords
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Journal
Cancers
Volume 10, Issue 2, Pages 45
Publisher
MDPI AG
Online
2018-02-07
DOI
10.3390/cancers10020045
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Note: Only part of the references are listed.- Upstairs, downstairs: spatial regulation of Hippo signalling
- (2018) Alexander Fulford et al. CURRENT OPINION IN CELL BIOLOGY
- Hepatic Hippo signaling inhibits protumoural microenvironment to suppress hepatocellular carcinoma
- (2017) Wantae Kim et al. GUT
- β1 integrin–dependent Rac/group I PAK signaling mediates YAP activation of Yes-associated protein 1 (YAP1) via NF2/merlin
- (2017) Hiba Sabra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Muscle Yap Is a Regulator of Neuromuscular Junction Formation and Regeneration
- (2017) Kai Zhao et al. JOURNAL OF NEUROSCIENCE
- Force-dependent breaching of the basement membrane
- (2017) Tammy T. Chang et al. MATRIX BIOLOGY
- Dystrophin–glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation
- (2017) Yuka Morikawa et al. NATURE
- The extracellular matrix protein agrin promotes heart regeneration in mice
- (2017) Elad Bassat et al. NATURE
- Mechanobiology of YAP and TAZ in physiology and disease
- (2017) Tito Panciera et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ
- (2017) Deanna N. Edwards et al. Science Signaling
- Glucocorticoid receptor signalling activates YAP in breast cancer
- (2017) Giovanni Sorrentino et al. Nature Communications
- YAP regulates cell mechanics by controlling focal adhesion assembly
- (2017) Giorgia Nardone et al. Nature Communications
- Agrin para-secreted by PDGF-activated human hepatic stellate cells promotes hepatocarcinogenesis in vitro and in vivo
- (2017) Xing Lv et al. Oncotarget
- Agrin as a Mechanotransduction Signal Regulating YAP through the Hippo Pathway
- (2017) Sayan Chakraborty et al. Cell Reports
- The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ
- (2017) Deanna N. Edwards et al. Science Signaling
- YAP/TAZ at the Roots of Cancer
- (2016) Francesca Zanconato et al. CANCER CELL
- Identification of a novel agrin-dependent pathway in cell signaling and adhesion within the erythroid niche
- (2016) A Anselmo et al. CELL DEATH AND DIFFERENTIATION
- Integrin signalling regulates YAP and TAZ to control skin homeostasis
- (2016) Ahmed Elbediwy et al. DEVELOPMENT
- Mechanisms of Hippo pathway regulation
- (2016) Zhipeng Meng et al. GENES & DEVELOPMENT
- p66 Shc Couples Mechanical Signals to RhoA through Focal Adhesion Kinase-Dependent Recruitment of p115-RhoGEF and GEF-H1
- (2016) Ru-Feng Wu et al. MOLECULAR AND CELLULAR BIOLOGY
- Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow
- (2016) Li Wang et al. NATURE
- A critical role for NF2 and the Hippo pathway in branching morphogenesis
- (2016) Antoine Reginensi et al. Nature Communications
- Integrin α2β1 inhibits MST1 kinase phosphorylation and activates Yes-associated protein oncogenic signaling in hepatocellular carcinoma
- (2016) Kwong-Fai Wong et al. Oncotarget
- Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
- (2015) Fa-Xing Yu et al. CELL
- A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis
- (2015) Shuying Shen et al. CELL RESEARCH
- Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway
- (2015) Youjun Li et al. CELL RESEARCH
- A laminin 511 matrix is regulated by TAZ and functions as the ligand for the α6Bβ1 integrin to sustain breast cancer stem cells
- (2015) Cheng Chang et al. GENES & DEVELOPMENT
- Adhesion to fibronectin regulates Hippo signaling via the FAK–Src–PI3K pathway
- (2015) Nam-Gyun Kim et al. JOURNAL OF CELL BIOLOGY
- Functional and Clinical Evidence That TAZ is a Candidate Oncogene in Hepatocellular Carcinoma
- (2015) Yan Guo et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The Hippo pathway effector YAP controls mouse hepatic stellate cell activation
- (2015) Inge Mannaerts et al. JOURNAL OF HEPATOLOGY
- Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancer
- (2015) Dean Yimlamai et al. JOURNAL OF HEPATOLOGY
- A YAP/TAZ-Regulated Molecular Signature Is Associated with Oral Squamous Cell Carcinoma
- (2015) S. E. Hiemer et al. MOLECULAR CANCER RESEARCH
- A molecular mechanotransduction pathway regulates collective migration of epithelial cells
- (2015) Tamal Das et al. NATURE CELL BIOLOGY
- Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth
- (2015) Francesca Zanconato et al. NATURE CELL BIOLOGY
- Mechanical strain induces E-cadherin-dependent Yap1 and -catenin activation to drive cell cycle entry
- (2015) B. W. Benham-Pyle et al. SCIENCE
- An oncogenic role of Agrin in regulating focal adhesion integrity in hepatocellular carcinoma
- (2015) Sayan Chakraborty et al. Nature Communications
- MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway
- (2015) Zhipeng Meng et al. Nature Communications
- YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers
- (2015) Claudia Stein et al. PLoS Genetics
- Mutant Gq/11 Promote Uveal Melanoma Tumorigenesis by Activating YAP
- (2014) Fa-Xing Yu et al. CANCER CELL
- Cytoskeletal Tension Inhibits Hippo Signaling through an Ajuba-Warts Complex
- (2014) Cordelia Rauskolb et al. CELL
- YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response
- (2014) Luca Azzolin et al. CELL
- Arhgef7 promotes activation of the Hippo pathway core kinase Lats
- (2014) Emad Heidary Arash et al. EMBO JOURNAL
- The extracellular matrix modulates the hallmarks of cancer
- (2014) M. W. Pickup et al. EMBO REPORTS
- Angiomotins link F-actin architecture to Hippo pathway signaling
- (2014) Sebastian Mana-Capelli et al. MOLECULAR BIOLOGY OF THE CELL
- Metabolic control of YAP and TAZ by the mevalonate pathway
- (2014) Giovanni Sorrentino et al. NATURE CELL BIOLOGY
- The Biology of YAP/TAZ: Hippo Signaling and Beyond
- (2014) Stefano Piccolo et al. PHYSIOLOGICAL REVIEWS
- Agrin and Perlecan Mediate Tumorigenic Processes in Oral Squamous Cell Carcinoma
- (2014) Rebeca Kawahara et al. PLoS One
- Expression and Clinical Significance of YAP, TAZ, and AREG in Hepatocellular Carcinoma
- (2014) Su-xia Han et al. Journal of Immunology Research
- Emerging roles of TEAD transcription factors and its coactivators in cancers
- (2013) Ajaybabu V. Pobbati et al. CANCER BIOLOGY & THERAPY
- Spatial Organization of Hippo Signaling at the Plasma Membrane Mediated by the Tumor Suppressor Merlin/NF2
- (2013) Feng Yin et al. CELL
- A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors
- (2013) Mariaceleste Aragona et al. CELL
- MT1-MMP-Dependent Control of Skeletal Stem Cell Commitment via a β1-Integrin/YAP/TAZ Signaling Axis
- (2013) Yi Tang et al. DEVELOPMENTAL CELL
- Phosphorylation of Angiomotin by Lats1/2 Kinases Inhibits F-actin Binding, Cell Migration, and Angiogenesis
- (2013) Xiaoming Dai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Actin-binding and Cell Proliferation Activities of Angiomotin Family Members Are Regulated by Hippo Pathway-mediated Phosphorylation
- (2013) Siew Wee Chan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A genetic screen identifies an LKB1–MARK signalling axis controlling the Hippo–YAP pathway
- (2013) Morvarid Mohseni et al. NATURE CELL BIOLOGY
- Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
- (2013) Fernando Calvo et al. NATURE CELL BIOLOGY
- Increased Expression of Yes-Associated Protein 1 in Hepatocellular Carcinoma with Stemness and Combined Hepatocellular-Cholangiocarcinoma
- (2013) Gi Jeong Kim et al. PLoS One
- Therapeutically targeting glypican-3 via a conformation-specific single-domain antibody in hepatocellular carcinoma
- (2013) M. Feng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1
- (2013) R. Fan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase
- (2013) Isabel Serrano et al. Nature Communications
- Yap- and Cdc42-Dependent Nephrogenesis and Morphogenesis during Mouse Kidney Development
- (2013) Antoine Reginensi et al. PLoS Genetics
- Nanoscale protein architecture of the kidney glomerular basement membrane
- (2013) Hani Suleiman et al. eLife
- Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling
- (2012) Fa-Xing Yu et al. CELL
- Structural basis of agrin-LRP4-MuSK signaling
- (2012) Y. Zong et al. GENES & DEVELOPMENT
- Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
- (2012) B. Zhao et al. GENES & DEVELOPMENT
- The extracellular matrix: A dynamic niche in cancer progression
- (2012) Pengfei Lu et al. JOURNAL OF CELL BIOLOGY
- Knockdown of GPC3 inhibits the proliferation of Huh7 hepatocellular carcinoma cells through down-regulation of YAP
- (2012) Hui-Lai Miao et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Transduction of mechanical and cytoskeletal cues by YAP and TAZ
- (2012) Georg Halder et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The YAP and TAZ transcription co-activators: Key downstream effectors of the mammalian Hippo pathway
- (2012) Wanjin Hong et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Sensing and Modulation of Invadopodia across a Wide Range of Rigidities
- (2011) Aron Parekh et al. BIOPHYSICAL JOURNAL
- The critical role of agrin in the hematopoietic stem cell niche
- (2011) C. Mazzon et al. BLOOD
- LATS1 tumor suppressor is a novel actin-binding protein and negative regulator of actin polymerization
- (2011) Stacy Visser-Grieve et al. CELL RESEARCH
- Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila
- (2011) B. G. Fernandez et al. DEVELOPMENT
- Hippo pathway regulation by cell morphology and stress fibers
- (2011) K.-I. Wada et al. DEVELOPMENT
- Modulating F-actin organization induces organ growth by affecting the Hippo pathway
- (2011) Leticia Sansores-Garcia et al. EMBO JOURNAL
- Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein
- (2011) B. Zhao et al. GENES & DEVELOPMENT
- Agrin Binds to the N-terminal Region of Lrp4 Protein and Stimulates Association between Lrp4 and the First Immunoglobulin-like Domain in Muscle-specific Kinase (MuSK)
- (2011) Wei Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor
- (2011) Murugan Paramasivam et al. MOLECULAR BIOLOGY OF THE CELL
- Role of YAP/TAZ in mechanotransduction
- (2011) Sirio Dupont et al. NATURE
- Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression
- (2011) Mina J Bissell et al. NATURE MEDICINE
- The Hippo Signaling Pathway in Development and Cancer
- (2010) Duojia Pan DEVELOPMENTAL CELL
- Induction of filopodia-like protrusions by transmembrane agrin: Role of agrin glycosaminoglycan chains and Rho-family GTPases
- (2010) Lin Lin et al. EXPERIMENTAL CELL RESEARCH
- A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF -TRCP
- (2010) B. Zhao et al. GENES & DEVELOPMENT
- The Hippo Tumor Pathway Promotes TAZ Degradation by Phosphorylating a Phosphodegron and Recruiting the SCFβ-TrCPE3 Ligase
- (2010) Chen-Ying Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Angiomotin-like Proteins Associate with and Negatively Regulate YAP1
- (2010) Wenqi Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma
- (2010) M Z Xu et al. ONCOGENE
- Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver
- (2010) L. Lu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis
- (2010) K.-P. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Integrins and Extracellular Matrix in Mechanotransduction
- (2010) M. A. Schwartz Cold Spring Harbor Perspectives in Biology
- Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma
- (2009) Michelle Z. Xu et al. CANCER
- Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene
- (2009) Dawang Zhou et al. CANCER CELL
- Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
- (2009) Kandice R. Levental et al. CELL
- TEADs Mediate Nuclear Retention of TAZ to Promote Oncogenic Transformation
- (2009) Siew Wee Chan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neurofibromatosis type 2
- (2009) Ashok R Asthagiri et al. LANCET
- MST Kinases Monitor Actin Cytoskeletal Integrity and Signal via c-Jun N-Terminal Kinase Stress-Activated Kinase To Regulate p21Waf1/Cip1 Stability
- (2009) R. M. Densham et al. MOLECULAR AND CELLULAR BIOLOGY
- Glypican 3 Expression in Human Nonneoplastic, Preneoplastic, and Neoplastic Tissues
- (2008) Daniel Baumhoer et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- Lrp4 Is a Receptor for Agrin and Forms a Complex with MuSK
- (2008) Natalie Kim et al. CELL
- Extracellular Matrix Rigidity Promotes Invadopodia Activity
- (2008) Nelson R. Alexander et al. CURRENT BIOLOGY
- The TEAD/TEF Family Protein Scalloped Mediates Transcriptional Output of the Hippo Growth-Regulatory Pathway
- (2008) Shian Wu et al. DEVELOPMENTAL CELL
- TEAD mediates YAP-dependent gene induction and growth control
- (2008) B. Zhao et al. GENES & DEVELOPMENT
- LRP4 Serves as a Coreceptor of Agrin
- (2008) Bin Zhang et al. NEURON
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