PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells

Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of function

(2013) Piero Pingitore et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

PNPLA3 I148M variant and hepatocellular carcinoma: A common genetic variant for a rare disease

(2013) Luca Valenti et al.   DIGESTIVE AND LIVER DISEASE

Further advances in the production of membrane proteins inPichia pastoris

(2013) Kristina Hedfalk   Bioengineered

The i148m Pnpla3 polymorphism influences serum adiponectin in patients with fatty liver and healthy controls

(2012) Luca Valenti et al.   BMC GASTROENTEROLOGY

PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals

(2012) Maria Antonella Burza et al.   DIGESTIVE AND LIVER DISEASE

Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro

(2012) Carlo Pirazzi et al.   JOURNAL OF HEPATOLOGY

Recombinant production of the human aquaporins in the yeastPichia pastoris(Invited Review)

(2012) Fredrik Öberg et al.   MOLECULAR MEMBRANE BIOLOGY

Mechanisms of hepatic fibrogenesis

(2011) Ursula E. Lee et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Retinyl ester hydrolases and their roles in vitamin A homeostasis

(2011) Renate Schreiber et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease

(2011) Silvia Sookoian et al.   HEPATOLOGY

Genome-wide association study of circulating retinol levels

(2011) Alison M. Mondul et al.   HUMAN MOLECULAR GENETICS

Retinoic Acid Treatment Enhances Lipid Oxidation and Inhibits Lipid Biosynthesis Capacities in the Liver of Mice

(2010) Jaume Amengual et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease

(2010) Luca Valenti et al.   HEPATOLOGY

Patatin-Like phospholipase domain-containing 3 I148M polymorphism, steatosis, and liver damage in chronic hepatitis C

(2010) Luca Valenti et al.   HEPATOLOGY

A feed-forward loop amplifies nutritional regulation of PNPLA3

(2010) Yongcheng Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent

(2009) S Romeo et al.   INTERNATIONAL JOURNAL OF OBESITY

A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis

(2009) Shaoqing He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of carboxylesterase and lipase genes in rat liver cell-types

(2008) Tommaso Mello et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RBP-to-retinol ratio, but not total RBP, is elevated in patients with type 2 diabetes

(2008) C. Erikstrup et al.   DIABETES OBESITY & METABOLISM

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

(2008) Scott L. Friedman   PHYSIOLOGICAL REVIEWS