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Metabolic and histological implications of intrahepatic triglyceride content in nonalcoholic fatty liver disease

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Treatment of NAFLD with diet, physical activity and exercise

(2017) Manuel Romero-Gómez et al.   JOURNAL OF HEPATOLOGY

Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD

(2017) Panu K. Luukkonen et al.   JOURNAL OF HEPATOLOGY

Novel association of TM6SF2 rs58542926 genotype with increased serum tyrosine levels and decreased apoB-100 particles in Finns

(2017) Daniel Seung Kim et al.   JOURNAL OF LIPID RESEARCH

Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci

(2017) Stefan Stender et al.   NATURE GENETICS

Exome-wide association study of plasma lipids in >300,000 individuals

(2017) Dajiang J Liu et al.   NATURE GENETICS

Mendelian randomization in cardiometabolic disease: challenges in evaluating causality

(2017) Michael V. Holmes et al.   Nature Reviews Cardiology

Non-Invasive Assessment of Liver Injury in Non-Alcoholic Fatty Liver Disease: A Review of Literature

(2016) M. Maida et al.   CURRENT MOLECULAR MEDICINE

The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent

(2016) Rosellina Margherita Mancina et al.   GASTROENTEROLOGY

Shared genetic effects between hepatic steatosis and fibrosis: A prospective twin study

(2016) Jeffrey Cui et al.   HEPATOLOGY

MERTK rs4374383 polymorphism affects the severity of fibrosis in non-alcoholic fatty liver disease

(2016) Salvatore Petta et al.   JOURNAL OF HEPATOLOGY

Nonalcoholic fatty liver disease: cause or consequence of type 2 diabetes?

(2016) Luca Valenti et al.   LIVER INTERNATIONAL

Genetics of nonalcoholic fatty liver disease

(2016) Paola Dongiovanni et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The genetic architecture of type 2 diabetes

(2016) Christian Fuchsberger et al.   NATURE

Epidemiological modifiers of non-alcoholic fatty liver disease: Focus on high-risk groups

(2015) Amedeo Lonardo et al.   DIGESTIVE AND LIVER DISEASE

Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease

(2015) Paul Angulo et al.   GASTROENTEROLOGY

Hepatic lipid droplet biology: Getting to the root of fatty liver

(2015) Douglas G. Mashek et al.   HEPATOLOGY

Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease

(2015) Paola Dongiovanni et al.   HEPATOLOGY

A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

(2015) Stephan Buch et al.   NATURE GENETICS

Genetic Factors in the Pathogenesis of Nonalcoholic Fatty Liver and Steatohepatitis

(2015) Paola Dongiovanni et al.   Biomed Research International

PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells

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Mendelian randomization: genetic anchors for causal inference in epidemiological studies

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Homozygous MTTP and APOB mutations may lead to hepatic steatosis and fibrosis despite metabolic differences in congenital hypocholesterolemia

(2014) Mathilde Di Filippo et al.   JOURNAL OF HEPATOLOGY

Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk

(2014) Oddgeir L Holmen et al.   NATURE GENETICS

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

(2014) Julia Kozlitina et al.   NATURE GENETICS

Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome

(2014) Hannele Yki-Järvinen   Lancet Diabetes & Endocrinology

Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan

(2013) Takuya Kitamoto et al.   HUMAN GENETICS

Use of allele scores as instrumental variables for Mendelian randomization

(2013) Stephen Burgess et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Hepatocellular cancer: The impact of obesity, type 2 diabetes and a multidisciplinary team

(2013) Jessica Dyson et al.   JOURNAL OF HEPATOLOGY

Hepatic fat loss in advanced nonalcoholic steatohepatitis: Are alterations in serum adiponectin the cause?

(2012) David van der Poorten et al.   HEPATOLOGY

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

(2012) Alisa K Manning et al.   NATURE GENETICS

Bariatric Surgery and Prevention of Type 2 Diabetes in Swedish Obese Subjects

(2012) Lena M.S. Carlsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Frequency and Outcomes of Liver Transplantation for Nonalcoholic Steatohepatitis in the United States

(2011) Michael R. Charlton et al.   GASTROENTEROLOGY

Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease

(2011) N. Kumashiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

(2011) Elizabeth K. Speliotes et al.   PLoS Genetics

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

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