标题
Human Multilineage 3D Spheroids as a Model of Liver Steatosis and Fibrosis
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 7, Pages 1629
出版商
MDPI AG
发表日期
2019-04-03
DOI
10.3390/ijms20071629
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice
- (2019) Daniel Lindén et al. Molecular Metabolism
- Recent Insights into the Pathogenesis of Nonalcoholic Fatty Liver Disease
- (2018) Juan Pablo Arab et al. Annual Review of Pathology-Mechanisms of Disease
- The role of PNPLA3 in health and disease
- (2018) Piero Pingitore et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Metabolic and hepatic effects of liraglutide, obeticholic acid and elafibranor in diet-induced obese mouse models of biopsy-confirmed nonalcoholic steatohepatitis
- (2018) Kirstine S Tølbøl et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Effects of free omega-3 carboxylic acids and fenofibrate on liver fat content in patients with hypertriglyceridemia and non-alcoholic fatty liver disease: A double-blind, randomized, placebo-controlled study
- (2018) Jan Oscarsson et al. Journal of Clinical Lipidology
- Human hepatic 3D spheroids as a model for steatosis and insulin resistance
- (2018) Mikael Kozyra et al. Scientific Reports
- Non-alcoholic fatty liver disease (NAFLD) models in drug discovery
- (2017) Banumathi K. Cole et al. Expert Opinion on Drug Discovery
- Increased risk of mortality by fibrosis stage in nonalcoholic fatty liver disease: Systematic review and meta-analysis
- (2017) Parambir S. Dulai et al. HEPATOLOGY
- Transforming growth factor beta-1 (TGF-β1) stimulates collagen synthesis in cultured rainbow trout cardiac fibroblasts
- (2017) Elizabeth F. Johnston et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver
- (2017) P. Dongiovanni et al. JOURNAL OF INTERNAL MEDICINE
- Mechanisms of hepatic stellate cell activation
- (2017) Takuma Tsuchida et al. Nature Reviews Gastroenterology & Hepatology
- GLP-1 Analogue, Exendin-4, Modulates MAPKs Activity but not the Heat Shock Response in Human HepG2 Cells
- (2017) Dhanya Madhu et al. Proteomics Clinical Applications
- Elafibranor, an Agonist of the Peroxisome Proliferator−Activated Receptor−α and −δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening
- (2016) Vlad Ratziu et al. GASTROENTEROLOGY
- Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes
- (2016) Zobair M. Younossi et al. HEPATOLOGY
- PNPLA3 overexpression results in reduction of proteins predisposing to fibrosis
- (2016) Piero Pingitore et al. HUMAN MOLECULAR GENETICS
- Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study
- (2016) Matthew James Armstrong et al. LANCET
- Hepatic adaptations to maintain metabolic homeostasis in response to fasting and refeeding in mice
- (2016) C. E. Geisler et al. Nutrition & Metabolism
- Activated hepatic stellate cells play pivotal roles in hepatocellular carcinoma cell chemoresistance and migration in multicellular tumor spheroids
- (2016) Yeonhwa Song et al. Scientific Reports
- The importance of the interaction between hepatocyte and hepatic stellate cells in fibrogenesis induced by fatty accumulation
- (2015) Pablo J. Giraudi et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- The Genetic Variant I148M inPNPLA3Is Associated With Increased Hepatic Retinyl-Palmitate Storage in Humans
- (2015) Marketa Kovarova et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- β-PDGF receptor expressed by hepatic stellate cells regulates fibrosis in murine liver injury, but not carcinogenesis
- (2015) Peri Kocabayoglu et al. JOURNAL OF HEPATOLOGY
- Statin use and non-alcoholic steatohepatitis in at risk individuals
- (2015) Paola Dongiovanni et al. JOURNAL OF HEPATOLOGY
- Treating liver fat and serum triglyceride levels in NAFLD, effects of PNPLA3 and TM6SF2 genotypes: Results from the WELCOME trial
- (2015) Eleonora Scorletti et al. JOURNAL OF HEPATOLOGY
- PNPLA3 I148M Variant Influences Circulating Retinol in Adults with Nonalcoholic Fatty Liver Disease or Obesity
- (2015) Alison Mondul et al. JOURNAL OF NUTRITION
- Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
- (2015) Brent A Neuschwander-Tetri et al. LANCET
- The interplay between hepatic stellate cells and hepatocytes in an in vitro model of NASH
- (2015) Varenka J. Barbero-Becerra et al. TOXICOLOGY IN VITRO
- Nonalcoholic fatty liver disease
- (2015) Elizabeth M. Brunt et al. Nature Reviews Disease Primers
- PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells
- (2014) Carlo Pirazzi et al. HUMAN MOLECULAR GENETICS
- Lipids in health and disease
- (2014) Joshua Finkelstein et al. NATURE
- Circulating Triacylglycerol Signatures in Nonalcoholic Fatty Liver Disease Associated With the I148M Variant in PNPLA3 and With Obesity
- (2013) J. Hyysalo et al. DIABETES
- Hepatic stellate cells in liver development, regeneration, and cancer
- (2013) Chunyue Yin et al. JOURNAL OF CLINICAL INVESTIGATION
- The burden of liver disease in Europe: A review of available epidemiological data
- (2013) Martin Blachier et al. JOURNAL OF HEPATOLOGY
- Transforming Growth Factor β1 Induces the Expression of Collagen Type I by DNA Methylation in Cardiac Fibroblasts
- (2013) Xiaodong Pan et al. PLoS One
- Effect of intracellular lipid accumulation in a new model of non-alcoholic fatty liver disease
- (2012) Norberto C Chavez-Tapia et al. BMC GASTROENTEROLOGY
- Adiponutrin Functions as a Nutritionally Regulated Lysophosphatidic Acid Acyltransferase
- (2012) Manju Kumari et al. Cell Metabolism
- Role of patatin-like phospholipase domain-containing 3 on lipid-induced hepatic steatosis and insulin resistance in rats
- (2012) Naoki Kumashiro et al. HEPATOLOGY
- Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro
- (2012) Carlo Pirazzi et al. JOURNAL OF HEPATOLOGY
- From 3D cell culture to organs-on-chips
- (2011) Dongeun Huh et al. TRENDS IN CELL BIOLOGY
- Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway
- (2010) Nitika Arora Gupta et al. HEPATOLOGY
- Modelling tissues in 3D: the next future of pharmaco-toxicology and food research?
- (2008) Giovanna Mazzoleni et al. Genes and Nutrition
- Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
- (2008) Scott L. Friedman PHYSIOLOGICAL REVIEWS
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