Cell circuits and niches controlling B cell development

Circuit Design Features of a Stable Two-Cell System

(2018) Xu Zhou et al.   CELL

Immunological memories of the bone marrow

(2018) Hyun-Dong Chang et al.   IMMUNOLOGICAL REVIEWS

Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation

(2018) Yongkui Wang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Murine Bone Marrow Niches from Hematopoietic Stem Cells to B Cells

(2018) Michel Aurrand-Lions et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cell circuits between B cell progenitors and IL-7+mesenchymal progenitor cells control B cell development

(2018) Chris Fistonich et al.   JOURNAL OF EXPERIMENTAL MEDICINE

mTORC1 plays an important role in osteoblastic regulation of B-lymphopoiesis

(2018) Sally K. Martin et al.   Scientific Reports

Osteoblasts Are Rapidly Ablated by Virus-Induced Systemic Inflammation following Lymphocytic Choriomeningitis Virus or Pneumonia Virus of Mice Infection in Mice

(2017) Steven Maltby et al.   JOURNAL OF IMMUNOLOGY

Metabolic gatekeeper function of B-lymphoid transcription factors

(2017) Lai N. Chan et al.   NATURE

Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis

(2017) Aurélie Hérault et al.   NATURE

T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow

(2017) Arielle Glatman Zaretsky et al.   Cell Reports

Niche heterogeneity in the bone marrow

(2016) Alexander Birbrair et al.   Annals of the New York Academy of Sciences

Tumor-secreted products repress B-cell lymphopoiesis in a murine model of breast cancer

(2016) Joshua M. Moreau et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Hematopoietic Stem Cell Niches Produce Lineage-Instructive Signals to Control Multipotent Progenitor Differentiation

(2016) Ana Cordeiro Gomes et al.   IMMUNITY

Sepsis-Induced Osteoblast Ablation Causes Immunodeficiency

(2016) Asuka Terashima et al.   IMMUNITY

Targeting of Mesenchymal Stromal Cells byCre-Recombinase Transgenes Commonly Used to Target Osteoblast Lineage Cells

(2016) Jingzhu Zhang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

RAG-mediated DNA double-strand breaks activate a cell type–specific checkpoint to inhibit pre–B cell receptor signals

(2016) Jeffrey J. Bednarski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses

(2016) Shu Zhen Chong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Retinoic Acid Receptor γ Regulates B and T Lymphopoiesis via Nestin-Expressing Cells in the Bone Marrow and Thymic Microenvironments

(2016) Chacko Joseph et al.   JOURNAL OF IMMUNOLOGY

Distinctive Mesenchymal-Parenchymal Cell Pairings Govern B Cell Differentiation in the Bone Marrow

(2016) Vionnie W.C. Yu et al.   Stem Cell Reports

Granulocyte colony-stimulating factor reprograms bone marrow stromal cells to actively suppress B lymphopoiesis in mice

(2015) R. B. Day et al.   BLOOD

CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance

(2015) Lauren A. Pitt et al.   CANCER CELL

Inflammatory Cell Migration in Rheumatoid Arthritis: A Comprehensive Review

(2015) Erin Nevius et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Ablation ofWntlessin endosteal niches impairs lymphopoiesis rather than HSCs maintenance

(2015) Jingjing Cao et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Memory CD8+ T cells colocalize with IL-7+ stromal cells in bone marrow and rest in terms of proliferation and transcription

(2015) Özen Sercan Alp et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

PTH Signaling in Osteoprogenitors Is Essential for B-Lymphocyte Differentiation and Mobilization

(2015) Cristina Panaroni et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Specific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow

(2015) Vionnie W.C. Yu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Oxysterols and EBI2 promote osteoclast precursor migration to bone surfaces and regulate bone mass homeostasis

(2015) Erin Nevius et al.   JOURNAL OF EXPERIMENTAL MEDICINE

RARγ is a negative regulator of osteoclastogenesis

(2015) Alanna C. Green et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Localized CCR2 Activation in the Bone Marrow Niche Mobilizes Monocytes by Desensitizing CXCR4

(2015) Hosung Jung et al.   PLoS One

Immature B Cell Egress from Bone Marrow Is SOCS3 Independent

(2015) Kristina Nadrah et al.   PLoS One

CXCL12/SDF-1 and CXCR4

(2015) Takashi Nagasawa   Frontiers in Immunology

Single-Cell Trajectory Detection Uncovers Progression and Regulatory Coordination in Human B Cell Development

(2014) Sean C. Bendall et al.   CELL

Vasculature-Associated Cells Expressing Nestin in Developing Bones Encompass Early Cells in the Osteoblast and Endothelial Lineage

(2014) Noriaki Ono et al.   DEVELOPMENTAL CELL

Osterix Marks Distinct Waves of Primitive and Definitive Stromal Progenitors during Bone Marrow Development

(2014) Toshihide Mizoguchi et al.   DEVELOPMENTAL CELL

Static and dynamic components synergize to form a stable survival niche for bone marrow plasma cells

(2014) Sandra Zehentmeier et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow

(2014) Thomas C. Beck et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The bone marrow niche for haematopoietic stem cells

(2014) Sean J. Morrison et al.   NATURE

Human memory T cells from the bone marrow are resting and maintain long-lasting systemic memory

(2014) A. Okhrimenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mesenchymal Stem Cell: Keystone of the Hematopoietic Stem Cell Niche and a Stepping-Stone for Regenerative Medicine

(2013) Paul S. Frenette et al.   Annual Review of Immunology

CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance

(2013) Adam Greenbaum et al.   NATURE

Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

(2013) Lei Ding et al.   NATURE

Arteriolar niches maintain haematopoietic stem cell quiescence

(2013) Yuya Kunisaki et al.   NATURE

Osterix-Cre Labeled Progenitor Cells Contribute to the Formation and Maintenance of the Bone Marrow Stroma

(2013) Yaling Liu et al.   PLoS One

The Response to and Repair of RAG-Mediated DNA Double-Strand Breaks

(2012) Beth A. Helmink et al.   Annual Review of Immunology

Sphingosine-1-Phosphate and Lymphocyte Egress from Lymphoid Organs

(2012) Jason G. Cyster et al.   Annual Review of Immunology

Proper desensitization of CXCR4 is required for lymphocyte development and peripheral compartmentalization in mice

(2012) K. Balabanian et al.   BLOOD

Adrenergic Nerves Govern Circadian Leukocyte Recruitment to Tissues

(2012) Christoph Scheiermann et al.   IMMUNITY

Antigen and cytokine receptor signals guide the development of the naïve mature B cell repertoire

(2012) Sarah L. Rowland et al.   IMMUNOLOGIC RESEARCH

Structural Basis for Galectin-1-dependent Pre-B Cell Receptor (Pre-BCR) Activation

(2012) Latifa Elantak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteoblast-specific overexpression of human interleukin-7 rescues the bone mass phenotype of interleukin-7-deficient female mice

(2012) Hector L Aguila et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Absence of sclerostin adversely affects B-cell survival

(2012) Corey J Cain et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Subnuclear cyclin D3 compartments and the coordinated regulation of proliferation and immunoglobulin variable gene repression

(2012) Sarah E. Powers et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Focal Adhesion Kinase Regulates the Localization and Retention of Pro-B Cells in Bone Marrow Microenvironments

(2012) S.-Y. Park et al.   JOURNAL OF IMMUNOLOGY

Identification of IL-7-Producing Cells in Primary and Secondary Lymphoid Organs Using IL-7-GFP Knock-In Mice

(2012) T. Hara et al.   JOURNAL OF IMMUNOLOGY

Endothelial and perivascular cells maintain haematopoietic stem cells

(2012) Lei Ding et al.   NATURE

A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation

(2012) Kyoko Ochiai et al.   NATURE IMMUNOLOGY

Galectin-1-expressing stromal cells constitute a specific niche for pre-BII cell development in mouse bone marrow

(2011) F. Mourcin et al.   BLOOD

Cxcl12 evolution - subfunctionalization of a ligand through altered interaction with the chemokine receptor

(2011) B. Boldajipour et al.   DEVELOPMENT

Bone Marrow Mesenchymal Stem and Progenitor Cells Induce Monocyte Emigration in Response to Circulating Toll-like Receptor Ligands

(2011) Chao Shi et al.   IMMUNITY

Liver-expressed Igκ superantigen induces tolerance of polyclonal B cells by clonal deletion not κ to λ receptor editing

(2011) Takayuki Ota et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human Bone Marrow Hosts Polyfunctional Memory CD4+ and CD8+ T Cells with Close Contact to IL-15-Producing Cells

(2011) D. Herndler-Brandstetter et al.   JOURNAL OF IMMUNOLOGY

In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche

(2011) Joji Fujisaki et al.   NATURE

Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2

(2011) Malay Mandal et al.   NATURE IMMUNOLOGY

FTY720 Regulates Bone Marrow Egress of Eosinophils and Modulates Late-Phase Skin Reaction in Mice

(2010) Kazunari Sugita et al.   AMERICAN JOURNAL OF PATHOLOGY

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

Bone marrow graft-versus-host disease: early destruction of hematopoietic niche after MHC-mismatched hematopoietic stem cell transplantation

(2010) Y. Shono et al.   BLOOD

CXCL12-CXCR4 chemokine signaling is essential for NK-cell development in adult mice

(2010) M. Noda et al.   BLOOD

Live imaging of neutrophil motility in a zebrafish model of WHIM syndrome

(2010) K. B. Walters et al.   BLOOD

The Essential Functions of Adipo-osteogenic Progenitors as the Hematopoietic Stem and Progenitor Cell Niche

(2010) Yoshiki Omatsu et al.   IMMUNITY

CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow

(2010) Kyle J. Eash et al.   JOURNAL OF CLINICAL INVESTIGATION

S1P1 receptor directs the release of immature B cells from bone marrow into blood

(2010) Maria L. Allende et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CpG Inhibits Pro-B Cell Expansion through a Cathepsin B-Dependent Mechanism

(2010) A. I. Lalanne et al.   JOURNAL OF IMMUNOLOGY

Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia

(2010) Marc H. G. P. Raaijmakers et al.   NATURE

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

A Role for S1P and S1P1 in Immature-B Cell Egress from Mouse Bone Marrow

(2010) João Pedro Pereira et al.   PLoS One

Temporal and spatial regulatory functions of the V(D)J recombinase

(2010) Stephen Desiderio   SEMINARS IN IMMUNOLOGY

Impaired B-cell development at the pre-BII-cell stage in galectin-1-deficient mice due to inefficient pre-BII/stromal cell interactions

(2009) M. Espeli et al.   BLOOD

S1P3 confers differential S1P-induced migration by autoreactive and non-autoreactive immature B cells and is required for normal B-cell development

(2009) Erin E. Donovan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development

(2009) M. A. Inlay et al.   GENES & DEVELOPMENT

Professional Memory CD4+ T Lymphocytes Preferentially Reside and Rest in the Bone Marrow

(2009) Koji Tokoyoda et al.   IMMUNITY

T-bet–dependent S1P5expression in NK cells promotes egress from lymph nodes and bone marrow

(2009) Craig N. Jenne et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cannabinoid receptor 2 mediates the retention of immature B cells in bone marrow sinusoids

(2009) João P Pereira et al.   NATURE IMMUNOLOGY

Visualization and Identification of IL-7 Producing Cells in Reporter Mice

(2009) Renata I. Mazzucchelli et al.   PLoS One

FLT3 ligand and not TSLP is the key regulator of IL-7-independent B-1 and B-2 B lymphopoiesis

(2008) C. T. Jensen et al.   BLOOD

Erythroblastic islands: niches for erythropoiesis

(2008) J. A. Chasis et al.   BLOOD

CCL3 and CXCL12 regulate trafficking of mouse bone marrow NK cell subsets

(2008) G. Bernardini et al.   BLOOD

S1P1 Receptor Signaling Overrides Retention Mediated by Gαi-Coupled Receptors to Promote T Cell Egress

(2008) Trung H.M. Pham et al.   IMMUNITY

Regulation of Immunoglobulin Light-Chain Recombination by the Transcription Factor IRF-4 and the Attenuation of Interleukin-7 Signaling

(2008) Kristen Johnson et al.   IMMUNITY

CXCR4 is required for the quiescence of primitive hematopoietic cells

(2008) Yuchun Nie et al.   JOURNAL OF EXPERIMENTAL MEDICINE

DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes

(2008) Andrea L. Bredemeyer et al.   NATURE

Haematopoietic stem cell release is regulated by circadian oscillations

(2008) Simón Méndez-Ferrer et al.   NATURE

Tumor Growth Decreases NK and B Cells as well as Common Lymphoid Progenitor

(2008) John Richards et al.   PLoS One

Osteoblastic regulation of B lymphopoiesis is mediated by Gs -dependent signaling pathways

(2008) J. Y. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA