Introducing the Chiral Transient Directing Group Strategy to Rhodium(III)‐Catalyzed Asymmetric C−H Activation

Enantioselective Synthesis of Atropisomers Featuring Pentatomic Heteroaromatics by Pd-Catalyzed C–H Alkynylation

(2019) Shuo Zhang et al.   ACS Catalysis

Scalable, Stereocontrolled Formal Syntheses of (+)-Isoschizandrin and (+)-Steganone: Development and Applications of Palladium(II)-Catalyzed Atroposelective C−H Alkynylation

(2018) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Planar-Chiral Rhodium(III) Catalyst with a Sterically Demanding Cyclopentadienyl Ligand and Its Application in the Enantioselective Synthesis of Dihydroisoquinolones

(2018) Evgeniya A. Trifonova et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Solvent-Dependent Asymmetric Synthesis of Alkynyl and Monofluoroalkenyl Isoindolinones by CpRhIII -Catalyzed C−H Activation

(2018) Teng Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-catalyzed enantioselective C(sp2)–H arylation of ferrocenyl ketones enabled by a chiral transient directing group

(2018) Jiancong Xu et al.   CHEMICAL COMMUNICATIONS

Controlling Pd(iv) reductive elimination pathways enables Pd(ii)-catalysed enantioselective C(sp3)−H fluorination

(2018) Hojoon Park et al.   Nature Chemistry

Transient imines as ‘next generation’ directing groups for the catalytic functionalisation of C–H bonds in a single operation

(2018) Sahra St John-Campbell et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Tailored trisubstituted chiral CpxRhIII catalysts for kinetic resolutions of phosphinic amides

(2018) Y. Sun et al.   Chemical Science

How Does Palladium–Amino Acid Cooperative Catalysis Enable Regio- and Stereoselective C(sp3)–H Functionalization in Aldehydes and Ketones? A DFT Mechanistic Study

(2018) Wenjing Liu et al.   ACS Catalysis

Combining transition metals and transient directing groups for C–H functionalizations

(2018) Trisha Bhattacharya et al.   RSC Advances

Natural Product Synthesis by C−H Activation

(2018) Soumya Kumar Sinha et al.   Asian Journal of Organic Chemistry

Advances in Development of C-H Activation/Functionalization Using a Catalytic Directing Group

(2018) Omer K. Rasheed et al.   ChemistrySelect

Transient Directing Groups for Transformative C–H Activation by Synergistic Metal Catalysis

(2018) Parthasarathy Gandeepan et al.   Chem

Chiral Carboxylic Acid Enabled Achiral Rhodium(III)-Catalyzed Enantioselective C−H Functionalization

(2018) Luqing Lin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C-H Bond Activation for the Synthesis of Heterocyclic Atropisomers Yields Hedgehog Pathway Inhibitors

(2018) Herbert Waldmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Access to P - and Axially Chiral Biaryl Phosphine Oxides by Enantioselective Cpx IrIII -Catalyzed C−H Arylations

(2018) Yun-Suk Jang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A comprehensive overview of directing groups applied in metal-catalysed C–H functionalisation chemistry

(2018) Carlo Sambiagio et al.   CHEMICAL SOCIETY REVIEWS

Enantioselective Synthesis of Chiral-at-Sulfur 1,2-Benzothiazines by Cpx RhIII -Catalyzed C−H Functionalization of Sulfoximines

(2018) Yang Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantiodivergent Desymmetrization in the Rhodium(III)-Catalyzed Annulation of Sulfoximines with Diazo Compounds

(2018) Bingxue Shen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Formal C(sp3 )−H Bond Activation in the Synthesis of Bioactive Spiropyrazolone Derivatives

(2018) Houhua Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Applications of Rh- and Pd-Catalyzed C(sp3 )-H Functionalization in Natural Product Total Synthesis

(2017) Patrick B. Brady et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

The Transient Directing Group Strategy: A New Trend in Transition-Metal-Catalyzed C–H Bond Functionalization

(2017) Tatiana Besset et al.   SYNTHESIS-STUTTGART

Rhodium(III)-Catalyzed Enantiotopic C−H Activation Enables Access to P -Chiral Cyclic Phosphinamides

(2016) Yang Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-catalyzed annulation of arenes with alkynes through weak chelation-assisted C–H activation

(2016) Yudong Yang et al.   CHEMICAL COMMUNICATIONS

Transition-Metal-Catalyzed C–H Bond Addition to Carbonyls, Imines, and Related Polarized π Bonds

(2016) Joshua R. Hummel et al.   CHEMICAL REVIEWS

Enantioselective Access to Spirocyclic Sultams by Chiral Cpx -Rhodium(III)-Catalyzed Annulations

(2016) Manh V. Pham et al.   CHEMISTRY-A EUROPEAN JOURNAL

Preparation of Enantiomerically Pure Perfluorobutanesulfinamide and Its Application to the Asymmetric Synthesis of α-Amino Acids

(2016) Apiwat Wangweerawong et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis and Application of Chiral Spiro Cp Ligands in Rhodium-Catalyzed Asymmetric Oxidative Coupling of Biaryl Compounds with Alkenes

(2016) Jun Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-catalyzed C–C coupling reactions via double C–H activation

(2016) Shuai-Shuai Li et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Advances in the development of catalytic tethering directing groups for C–H functionalization reactions

(2016) Huan Sun et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Functionalization of C(sp3)-H bonds using a transient directing group

(2016) F.-L. Zhang et al.   SCIENCE

Rh(III)-Catalyzed Aryl and Alkenyl C–H Bond Addition to Diverse Nitroalkenes

(2016) Tyler J. Potter et al.   ACS Catalysis

Substrate Activation Strategies in Rhodium(III)-Catalyzed Selective Functionalization of Arenes

(2015) Guoyong Song et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chiral Cyclopentadienyls: Enabling Ligands for Asymmetric Rh(III)-Catalyzed C–H Functionalizations

(2015) Baihua Ye et al.   ACCOUNTS OF CHEMICAL RESEARCH

Enantioselective Synthesis of Spiroindenes by Enol-Directed Rhodium(III)-Catalyzed CH Functionalization and Spiroannulation

(2015) Suresh Reddy Chidipudi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition-Metal-Catalyzed Direct Addition of Unactivated C–H Bonds to Polar Unsaturated Bonds

(2015) Lei Yang et al.   CHEMICAL REVIEWS

Transition metal-catalyzed ketone-directed or mediated C–H functionalization

(2015) Zhongxing Huang et al.   CHEMICAL SOCIETY REVIEWS

Asymmetric Dearomatization of Naphthols via a Rh-Catalyzed C(sp2)–H Functionalization/Annulation Reaction

(2015) Jun Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Cyclopentadienyl Ligands Enable a Rhodium(III)-Catalyzed Enantioselective Access to Hydroxychromanes and Phthalides

(2015) Nicolai Cramer et al.   SYNLETT

Transition metal-catalyzed C–H bond functionalizations by the use of diverse directing groups

(2015) Zhengkai Chen et al.   Organic Chemistry Frontiers

Construction of Axial Chirality by Rhodium-Catalyzed Asymmetric Dehydrogenative Heck Coupling of Biaryl Compounds with Alkenes

(2014) Jun Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Isoindolones by Chiral Cyclopentadienyl-Rhodium(III)-Catalyzed CH Functionalizations

(2014) Baihua Ye et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C–H Functionalization in the Synthesis of Amino Acids and Peptides

(2014) Anaïs F. M. Noisier et al.   CHEMICAL REVIEWS

Phthalides and Phthalans: Synthetic Methodologies and Their Applications in the Total Synthesis

(2014) Raju Karmakar et al.   CHEMICAL REVIEWS

Arene C–H functionalisation using a removable/modifiable or a traceless directing group strategy

(2014) Fengzhi Zhang et al.   CHEMICAL SOCIETY REVIEWS

Asymmetric Synthesis of α-Branched Amines via Rh(III)-Catalyzed C–H Bond Functionalization

(2014) Apiwat Wangweerawong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transition metal-catalyzed direct nucleophilic addition of C–H bonds to carbon–heteroatom double bonds

(2014) Xi-Sha Zhang et al.   Chemical Science

Recent advances in directed C–H functionalizations using monodentate nitrogen-based directing groups

(2014) Min Zhang et al.   Organic Chemistry Frontiers

Chiral Cp-Rhodium(III)-Catalyzed Asymmetric Hydroarylations of 1,1-Disubstituted Alkenes

(2013) Baihua Ye et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Tunable Class of Chiral Cp Ligands for Enantioselective Rhodium(III)-Catalyzed C–H Allylations of Benzamides

(2013) Baihua Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C–H bond activation enables the rapid construction and late-stage diversification of functional molecules

(2013) Joanna Wencel-Delord et al.   Nature Chemistry

Transition-metal-catalyzed additions of C–H bonds to C–X (X = N, O) multiple bonds via C–H bond activation

(2013) Guobing Yan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Rhodium(III)-Amine Dual Catalysis for the Oxidative Coupling of Aldehydes by Directed C–H Activation: Synthesis of Phthalides

(2013) Peng Wen Tan et al.   ORGANIC LETTERS

Cyclometalation of (2R,5R)-2,5-Diphenylpyrrolidine and 2-Phenyl-2-imidazoline Ligands with Half-Sandwich Iridium(III) and Rhodium(III) Complexes

(2013) Elias Féghali et al.   ORGANOMETALLICS

CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals

(2012) Junichiro Yamaguchi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C–C, C–O and C–N bond formation via rhodium(iii)-catalyzed oxidative C–H activation

(2012) Guoyong Song et al.   CHEMICAL SOCIETY REVIEWS

Cooperative Catalysis Approach to Intramolecular Hydroacylation

(2012) Evgeny V. Beletskiy et al.   JOURNAL OF ORGANIC CHEMISTRY

Biotinylated Rh(III) Complexes in Engineered Streptavidin for Accelerated Asymmetric C-H Activation

(2012) T. K. Hyster et al.   SCIENCE

Chiral Cyclopentadienyl Ligands as Stereocontrolling Element in Asymmetric C-H Functionalization

(2012) B. Ye et al.   SCIENCE

Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions

(2011) Keary M. Engle et al.   ACCOUNTS OF CHEMICAL RESEARCH

Removable Directing Groups in Organic Synthesis and Catalysis

(2011) Géraldine Rousseau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reaction of Chiral Secondary Amines with [(η5-C5Me5)MCl2]2(M = Rh(III), Ir(III)): Cyclometalation with or without Dehydrogenation

(2011) Laurent Barloy et al.   ORGANOMETALLICS

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Metal−Organic Cooperative Catalysis in C−H and C−C Bond Activation and Its Concurrent Recovery

(2008) Young Jun Park et al.   ACCOUNTS OF CHEMICAL RESEARCH