Transition metal-catalyzed ketone-directed or mediated C–H functionalization

Transition metal-catalyzed direct remote C–H functionalization of alkyl groups via C(sp3)–H bond activation

(2015) Guanyinsheng Qiu et al.   Organic Chemistry Frontiers

A New Iron(III)–Salen Catalyst for Enantioselective Conia-ene Carbocyclization

(2014) Subrata Shaw et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Branch-Selective, Iridium-Catalyzed Hydroarylation of Monosubstituted Alkenes via a Cooperative Destabilization Strategy

(2014) Giacomo E. M. Crisenza et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt-Catalyzed Hydroarylative Cyclization of 1,6-Enynes with Aromatic Ketones and Esters via C–H Activation

(2014) Rajagopal Santhoshkumar et al.   ORGANIC LETTERS

Regioselective ketone  -alkylation with simple olefins via dual activation

(2014) F. Mo et al.   SCIENCE

Catalytic CC bond forming transformations via direct β-CH functionalization of carbonyl compounds

(2014) Zhongxing Huang et al.   TETRAHEDRON LETTERS

Sunlight photocatalyzed regioselective β-alkylation and acylation of cyclopentanones

(2014) Megumi Okada et al.   Chemical Science

Recent advances in directed C–H functionalizations using monodentate nitrogen-based directing groups

(2014) Min Zhang et al.   Organic Chemistry Frontiers

Silver(I)-Catalyzed Conia-Ene Reaction: Synthesis of 3-Pyrrolinesviaa 5-endo-digCyclization

(2013) Siva Senthil Kumar Boominathan et al.   ADVANCED SYNTHESIS & CATALYSIS

Regio- and Chemoselective CH Chlorination/Bromination of Electron-Deficient Arenes by Weak Coordination and Study of Relative Directing-Group Abilities

(2013) Xiuyun Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Functionalization of C(sp2)H and C(sp3)H Bonds by Using Bidentate Directing Groups

(2013) Guy Rouquet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ru(ii)-catalyzed intermolecular C–H amidation of weakly coordinating ketones

(2013) Qing-Zhong Zheng et al.   CHEMICAL COMMUNICATIONS

Ru(ii)-catalyzed intermolecular ortho-C–H amidation of aromatic ketones with sulfonyl azides

(2013) M. Bhanuchandra et al.   CHEMICAL COMMUNICATIONS

Ruthenium-Catalyzed Direct CH Amidation of Arenes Including Weakly Coordinating Aromatic Ketones

(2013) Jiyu Kim et al.   CHEMISTRY-A EUROPEAN JOURNAL

Direct β-Functionalization of Cyclic Ketones with Aryl Ketones via the Merger of Photoredox and Organocatalysis

(2013) Filip R. Petronijević et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Direct β-Arylation of Simple Ketones with Aryl Iodides

(2013) Zhongxing Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aerobic Dehydrogenation of Cyclohexanone to Phenol Catalyzed by Pd(TFA)2/2-Dimethylaminopyridine: Evidence for the Role of Pd Nanoparticles

(2013) Doris Pun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aerobic Dehydrogenation of Cyclohexanone to Cyclohexenone Catalyzed by Pd(DMSO)2(TFA)2: Evidence for Ligand-Controlled Chemoselectivity

(2013) Tianning Diao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Broadening the catalyst and reaction scope of regio- and chemoselective C–H oxygenation: a convenient and scalable approach to 2-acylphenols by intriguing Rh(ii) and Ru(ii) catalysis

(2013) Gang Shan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Palladium-Catalyzed ortho-CH-Bond Oxygenation of Aromatic Ketones

(2013) Pui Ying Choy et al.   ORGANIC LETTERS

Synthesis of Indene Frameworks via Rhodium-Catalyzed Cascade Cyclization of Aromatic Ketone and Unsaturated Carbonyl Compounds

(2013) Xian-Ying Shi et al.   ORGANIC LETTERS

Photoredox Activation for the Direct  -Arylation of Ketones and Aldehydes

(2013) M. T. Pirnot et al.   SCIENCE

Synthesis ofortho-Acylphenols through the Palladium-Catalyzed Ketone-Directed Hydroxylation of Arenes

(2012) Fanyang Mo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd-Catalyzed CH Oxygenation with TFA/TFAA: Expedient Access to Oxygen-Containing Heterocycles and Late-Stage Drug Modification

(2012) Gang Shan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antiviral activity of (+)-sattabacin against varicella zoster

(2012) Serena R. Mancha et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Pd-catalyzed double C–H bond activation of diaryl ketones for the synthesis of fluorenones

(2012) Parthasarathy Gandeepan et al.   CHEMICAL COMMUNICATIONS

Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization

(2012) Percia Beatrice Arockiam et al.   CHEMICAL REVIEWS

C–C, C–O and C–N bond formation via rhodium(iii)-catalyzed oxidative C–H activation

(2012) Guoyong Song et al.   CHEMICAL SOCIETY REVIEWS

Transition-Metal-Free Superbase-Promoted Stereoselective α-Vinylation of Ketones with Arylacetylenes: A General Strategy for Synthesis of β,γ-Unsaturated Ketones

(2012) Boris A. Trofimov et al.   JOURNAL OF ORGANIC CHEMISTRY

High-Yielding, Versatile, and Practical [Rh(III)Cp*]-Catalyzed Ortho Bromination and Iodination of Arenes

(2012) Nils Schröder et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Fluorenone Derivatives through Pd-Catalyzed Dehydrogenative Cyclization

(2012) Hu Li et al.   ORGANIC LETTERS

Ruthenium-Catalyzed C–H Bond Oxygenations with Weakly Coordinating Ketones

(2012) Vedhagiri S. Thirunavukkarasu et al.   ORGANIC LETTERS

Cu(I)-catalyzed α-alkylation of ketones with styrene derivatives

(2012) Shohei Majima et al.   TETRAHEDRON LETTERS

Removable Directing Groups in Organic Synthesis and Catalysis

(2011) Géraldine Rousseau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Carbocyclization of Alkynyl Ketones Proceeding through a Carbopalladation Pathway

(2011) Natalia Chernyak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regioselective Synthesis of Indenols by Rhodium-Catalyzed CH Activation and Carbocyclization of Aryl Ketones and Alkynes

(2011) Krishnamoorthy Muralirajan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient Gold(I)-Catalyzed Direct Intramolecular Hydroalkylation of Unactivated Alkenes with α-Ketones

(2011) Ya-Ping Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

La/Ag Heterobimetallic Cooperative Catalysis: A Catalytic Asymmetric Conia-Ene Reaction

(2011) Akinobu Matsuzawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds

(2011) Charles S. Yeung et al.   CHEMICAL REVIEWS

Transition metal-catalyzed arylation of unactivated C(sp3)–H bonds

(2011) Olivier Baudoin   CHEMICAL SOCIETY REVIEWS

Towards mild metal-catalyzed C–H bond activation

(2011) Joanna Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

Ruthenium-Catalyzed Regioselective Cyclization of Aromatic Ketones with Alkynes: An Efficient Route to Indenols and Benzofulvenes

(2011) Ravi Kiran Chinnagolla et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Intermolecular Directed C−H Amidation of Aromatic Ketones

(2011) Bin Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diverse Strategies toward Indenol and Fulvene Derivatives: Rh-Catalyzed C−H Activation of Aryl Ketones Followed by Coupling with Internal Alkynes

(2011) Frederic W. Patureau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Cyclic Enones via Direct Palladium-Catalyzed Aerobic Dehydrogenation of Ketones

(2011) Tianning Diao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ruthenium-CatalyzedOrtho-Alkenylation of Aromatic Ketones with Alkenes by C–H Bond Activation

(2011) Kishor Padala et al.   ORGANIC LETTERS

Direct aerobic α,β-dehydrogenation of aldehydes and ketones with a Pd(TFA)2/4,5-diazafluorenone catalyst

(2011) Tianning Diao et al.   Chemical Science

General palladium-catalyzed aerobic dehydrogenation to generate double bonds

(2011) Weiming Gao et al.   Chemical Science

Challenge and progress: palladium-catalyzed sp3 C–H activation

(2011) Hu Li et al.   Catalysis Science & Technology

Rhodium-Catalyzed Oxidative Olefination of CH Bonds in Acetophenones and Benzamides

(2010) Frederic W. Patureau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-Catalyzed α-Arylation of Carbonyl and Related Molecules: Novel Trends in CC Bond Formation by CH Bond Functionalization

(2010) Carin C. C. Johansson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Addition of Metal Enolate Derivatives to Unactivated Carbon−Carbon Multiple Bonds

(2010) Fabrice Dénès et al.   CHEMICAL REVIEWS

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Catalytic C–H functionalization by metalloporphyrins: recent developments and future directions

(2010) Hongjian Lu et al.   CHEMICAL SOCIETY REVIEWS

Base-Catalyzed Stereoselective Vinylation of Ketones with Arylacetylenes: A New C(sp3)C(sp2) Bond-Forming Reaction

(2010) Boris A. Trofimov et al.   CHEMISTRY-A EUROPEAN JOURNAL

Functionalization of Organic Molecules by Transition-Metal-Catalyzed C(sp3)H Activation

(2010) Rodolphe Jazzar et al.   CHEMISTRY-A EUROPEAN JOURNAL

One-Pot Syntheses of α,β-Unsaturated Carbonyl Compounds through Palladium-Mediated Dehydrogenation of Ketones, ­Aldehydes, Esters, Lactones and Amides

(2010) Jacques Muzart   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Phenanthrone Derivatives fromsec-Alkyl Aryl Ketones and Aryl Halides via a Palladium-Catalyzed Dual C−H Bond Activation and Enolate Cyclization

(2010) Parthasarathy Gandeepan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Room-Temperature Regioselective C−H/Olefin Coupling of Aromatic Ketones Using an Activated Ruthenium Catalyst with a Carbonyl Ligand and Structural Elucidation of Key Intermediates

(2010) Fumitoshi Kakiuchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gold-catalysed room-temperature cycloisomerisation of alkynes and unactivated enolisable ketones

(2010) Paul W. Davies et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Ruthenium Chloride as an Efficient Catalytic Precursor for Hydroarylation Reactions via C−H bond Activation

(2010) Marc-Olivier Simon et al.   ORGANIC LETTERS

Transition-Metal-Catalyzed Direct Arylation of (Hetero)Arenes by CH Bond Cleavage

(2009) Lutz Ackermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed CH Activation/CC Cross-Coupling Reactions: Versatility and Practicality

(2009) Xiao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition Metal-Catalyzed Direct Arylation of Substrates with Activated sp3-Hybridized C−H Bonds and Some of Their Synthetic Equivalents with Aryl Halides and Pseudohalides

(2009) Fabio Bellina et al.   CHEMICAL REVIEWS

Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation

(2009) Denise A. Colby et al.   CHEMICAL REVIEWS

C−H Activation for the Construction of C−B Bonds

(2009) Ibraheem A. I. Mkhalid et al.   CHEMICAL REVIEWS

C−C Bond Formation via C−H Bond Activation Under Protic Conditions: On the Role of Phosphane Ligand and Cosolvent

(2009) Marc-Olivier Simon et al.   JOURNAL OF ORGANIC CHEMISTRY

Brønsted Base/Lewis Acid Cooperative Catalysis in the Enantioselective Conia-Ene Reaction

(2009) Ting Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C−C Bond Formation via C−H Bond Activation Using an in Situ-Generated Ruthenium Catalyst

(2009) Rémi Martinez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unique Effect of Coordination of an Alkene Moiety in Products on Ruthenium-Catalyzed Chemoselective C−H Alkenylation

(2009) Satoshi Ueno et al.   ORGANIC LETTERS

Highly Regio-, Diastereo-, and Enantioselective [2+2+2] Cycloaddition of 1,6-Enynes with Electron-Deficient Ketones Catalyzed by a Cationic RhI/H8-binap Complex

(2008) Ken Tanaka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Asymmetric Conjugate Addition of Aryl-Metal Species

(2008) Andrey Gutnov   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Cationic iridium–BINAP complex-catalyzed addition of aryl ketones to alkynes and alkenes via directed C–H bond cleavage

(2008) Kyoji Tsuchikama et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Efficient Formation of Ring Structures Utilizing Multisite Activation by Indium Catalysis

(2008) Yoshimitsu Itoh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transition metal-free addition of ketones or nitriles to 1,3-dienes

(2007) Jean-Marc Gaudin et al.   CHEMICAL COMMUNICATIONS