Humanized mouse models of immunological diseases and precision medicine
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Humanized mouse models of immunological diseases and precision medicine
Authors
Keywords
-
Journal
MAMMALIAN GENOME
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2019-03-07
DOI
10.1007/s00335-019-09796-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Recent progress in therapeutic antibodies for cancer immunotherapy
- (2018) Anthony Lee et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy
- (2018) Minan Wang et al. FASEB JOURNAL
- A human immune system mouse model with robust lymph node development
- (2018) Yan Li et al. NATURE METHODS
- Too much of a good thing?
- (2018) Jocelyn Kaiser SCIENCE
- Cancer immune therapy for lymphoid malignancies: recent advances
- (2018) Uffe Klausen et al. Seminars in Immunopathology
- Rational Design of Mouse Models for Cancer Research
- (2018) Marietta Landgraf et al. TRENDS IN BIOTECHNOLOGY
- Next generation immune-checkpoints for cancer therapy
- (2018) Chiara Donini et al. Journal of Thoracic Disease
- A Humanized Mouse Model Generated Using Surplus Neonatal Tissue
- (2018) Matthew E. Brown et al. Stem Cell Reports
- Further Advances in Cancer Immunotherapy: Going Beyond Checkpoint Blockade
- (2018) Robert W. Wilkinson et al. Frontiers in Immunology
- Enhanced Antibody Responses in a Novel NOG Transgenic Mouse with Restored Lymph Node Organogenesis
- (2018) Takeshi Takahashi et al. Frontiers in Immunology
- Generation of Human Immunosuppressive Myeloid Cell Populations in Human Interleukin-6 Transgenic NOG Mice
- (2018) Asami Hanazawa et al. Frontiers in Immunology
- Introduction of Human Flt3-L and GM-CSF into Humanized Mice Enhances the Reconstitution and Maturation of Myeloid Dendritic Cells and the Development of Foxp3+CD4+ T Cells
- (2018) Ryutaro Iwabuchi et al. Frontiers in Immunology
- Gene expression variability across cells and species shapes innate immunity
- (2018) Tzachi Hagai et al. NATURE
- A humanized mouse model of anaphylactic peanut allergy
- (2017) Oliver T. Burton et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Haematopoietic stem and progenitor cells from human pluripotent stem cells
- (2017) Ryohichi Sugimura et al. NATURE
- Humanized mouse model supports development, function, and tissue residency of human natural killer cells
- (2017) Dietmar Herndler-Brandstetter et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Type 1 diabetes induction in humanized mice
- (2017) Shulian Tan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NOG-hIL-4-Tg, a new humanized mouse model for producing tumor antigen-specific IgG antibody by peptide vaccination
- (2017) Yoshie Kametani et al. PLoS One
- Long-term maintenance of peripheral blood derived human NK cells in a novel human IL-15- transgenic NOG mouse
- (2017) Ikumi Katano et al. Scientific Reports
- Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID “Meet the Experts” 2015 Workshop Summary
- (2016) Ramesh Akkina et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- Emergence and Evolution of Secondary Lymphoid Organs
- (2016) Harold R. Neely et al. Annual Review of Cell and Developmental Biology
- The Emerging Hallmarks of Cancer Metabolism
- (2016) Natalya N. Pavlova et al. Cell Metabolism
- A novel Flt3-deficient HIS mouse model with selective enhancement of human DC development
- (2016) Yan Li et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- T follicular regulatory cells
- (2016) Peter T. Sage et al. IMMUNOLOGICAL REVIEWS
- Innate lymphoid cells in secondary lymphoid organs
- (2016) Yotam E. Bar-Ephraïm et al. IMMUNOLOGICAL REVIEWS
- Genetically modified human CD4+T cells can be evaluatedin vivowithout lethal graft-versus-host disease
- (2016) Riyasat Ali et al. IMMUNOLOGY
- Humanized mouse model of mast cell–mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis
- (2016) Paul J. Bryce et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Respiratory Syncytial Virus (RSV) Pulmonary Infection in Humanized Mice Induces Human Anti-RSV Immune Responses and Pathology
- (2016) Anurag Sharma et al. JOURNAL OF VIROLOGY
- Improved Human Erythropoiesis and Platelet Formation in Humanized NSGW41 Mice
- (2016) Susann Rahmig et al. Stem Cell Reports
- Fundamentals of cancer metabolism
- (2016) R. J. DeBerardinis et al. Science Advances
- TGN1412 Induces Lymphopenia and Human Cytokine Release in a Humanized Mouse Model
- (2016) Sabrina Weißmüller et al. PLoS One
- Humanized Mouse Models for Transplant Immunology
- (2015) L. L. Kenney et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Generation of β cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice
- (2015) J. Babad et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Islet formation in mice and men: lessons for the generation of functional insulin-producing β-cells from human pluripotent stem cells
- (2015) Gopika Nair et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Humanized hemato-lymphoid system mice
- (2015) A. P. A. Theocharides et al. HAEMATOLOGICA
- CXCL13 Responsiveness but Not CXCR5 Expression by Late Transitional B Cells Initiates Splenic White Pulp Formation
- (2015) Harold R. Neely et al. JOURNAL OF IMMUNOLOGY
- The truth about fetal tissue research
- (2015) Meredith Wadman NATURE
- Pathophysiology of T follicular helper cells in humans and mice
- (2015) Hideki Ueno et al. NATURE IMMUNOLOGY
- Humanized hemato-lymphoid system mice
- (2015) A. P. A. Theocharides et al. HAEMATOLOGICA
- Efficient Generation of NKX6-1+ Pancreatic Progenitors from Multiple Human Pluripotent Stem Cell Lines
- (2015) M. Cristina Nostro et al. Stem Cell Reports
- Generation of Functional Human Pancreatic β Cells In Vitro
- (2014) Felicia W. Pagliuca et al. CELL
- A Humanized Mouse Model of Autoimmune Insulitis
- (2014) Ashley A. Viehmann Milam et al. DIABETES
- T Follicular Helper Cell Differentiation, Function, and Roles in Disease
- (2014) Shane Crotty IMMUNITY
- Generation of improved humanized mouse models for human infectious diseases
- (2014) Michael A. Brehm et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Production of bone marrow, liver, thymus (BLT) humanized mice on the C57BL/6 Rag2−/−γc−/−CD47−/− background
- (2014) Kerry J. Lavender et al. JOURNAL OF IMMUNOLOGICAL METHODS
- FLT3-Ligand Treatment of Humanized Mice Results in the Generation of Large Numbers of CD141+ and CD1c+ Dendritic Cells In Vivo
- (2014) Y. Ding et al. JOURNAL OF IMMUNOLOGY
- Preclinical research: Make mouse studies work
- (2014) Steve Perrin NATURE
- Development and function of human innate immune cells in a humanized mouse model
- (2014) Anthony Rongvaux et al. NATURE BIOTECHNOLOGY
- An AAV Vector-Mediated Gene Delivery Approach Facilitates Reconstitution of Functional Human CD8+ T Cells in Mice
- (2014) Jing Huang et al. PLoS One
- Genomic responses in mouse models greatly mimic human inflammatory diseases
- (2014) Keizo Takao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reply to Warren et al. and Shay et al.: Commonalities across species do exist and are potentially important
- (2014) Keizo Takao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mice are not men
- (2014) H. Shaw Warren et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hope in a mouse
- (2014) J. Couzin-Frankel SCIENCE
- Generation of insulin-producing β-like cells from human iPS cells in a defined and completely xeno-free culture system
- (2014) Hussain Md. Shahjalal et al. Journal of Molecular Cell Biology
- APOBEC3D and APOBEC3F Potently Promote HIV-1 Diversification and Evolution in Humanized Mouse Model
- (2014) Kei Sato et al. PLoS Pathogens
- Human Hemato-Lymphoid System Mice: Current Use and Future Potential for Medicine
- (2013) Anthony Rongvaux et al. Annual Review of Immunology
- Mice Engrafted with Human Fetal Thymic Tissue and Hematopoietic Stem Cells Develop Pathology Resembling Chronic Graft-versus-Host Disease
- (2013) Jennifer L. Lockridge et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment
- (2013) T. Yamauchi et al. BLOOD
- BLT-humanized C57BL/6 Rag2-/- c-/-CD47-/- mice are resistant to GVHD and develop B- and T-cell immunity to HIV infection
- (2013) K. J. Lavender et al. BLOOD
- Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice
- (2013) Jinhee Lee et al. BMC IMMUNOLOGY
- Human immune system development and survival of non-obese diabetic (NOD)-scid IL2rγnull(NSG) mice engrafted with human thymus and autologous haematopoietic stem cells
- (2013) L. Covassin et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Humanized mice for the study of infectious diseases
- (2013) Michael A Brehm et al. CURRENT OPINION IN IMMUNOLOGY
- How predictive are in vitro assays for cytokine release syndrome in vivo? A comparison of methods reveals worrying differences in sensitivity and frequency of response
- (2013) Susan J. Thorpe et al. CYTOKINE
- Establishment of a Human Allergy Model Using Human IL-3/GM-CSF-Transgenic NOG Mice
- (2013) R. Ito et al. JOURNAL OF IMMUNOLOGY
- Genomic responses in mouse models poorly mimic human inflammatory diseases
- (2013) Junhee Seok et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo
- (2013) Alireza Rezania et al. STEM CELLS
- Full reconstitution of human platelets in humanized mice after macrophage depletion
- (2012) Z. Hu et al. BLOOD
- Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2r null mice is enhanced by transgenic expression of membrane-bound human SCF
- (2012) M. A. Brehm et al. BLOOD
- A humanised mouse model of cytokine release: Comparison of CD3-specific antibody fragments
- (2012) S.L. Malcolm et al. JOURNAL OF IMMUNOLOGICAL METHODS
- IL-2 receptor γ-chain molecule is critical for intestinal T-cell reconstitution in humanized mice
- (2012) P W Denton et al. Mucosal Immunology
- Graft versus Host Disease in the Bone Marrow, Liver and Thymus Humanized Mouse Model
- (2012) Matthew B. Greenblatt et al. PLoS One
- Islet-Specific CTL Cloned from a Type 1 Diabetes Patient Cause Beta-Cell Destruction after Engraftment into HLA-A2 Transgenic NOD/SCID/IL2RG Null Mice
- (2012) Wendy W. J. Unger et al. PLoS One
- A Model for Personalized in Vivo Analysis of Human Immune Responsiveness
- (2012) H. Kalscheuer et al. Science Translational Medicine
- Immunology Taught by Humans
- (2012) M. M. Davis Science Translational Medicine
- Preparation of pancreatic β-cells from human iPS cells with small molecules
- (2012) Masaki Hosoya Islets
- Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor-, granulocyte-macrophage colony-stimulating factor-, and interleukin-3-expressing NOD-SCID IL2R null humanized mice
- (2011) E. Billerbeck et al. BLOOD
- Ipilimumab: An Anti-CTLA-4 Antibody for Metastatic Melanoma
- (2011) E. J. Lipson et al. CLINICAL CANCER RESEARCH
- Human Natural Regulatory T Cell Development, Suppressive Function, and Postthymic Maturation in a Humanized Mouse Model
- (2011) T. Onoe et al. JOURNAL OF IMMUNOLOGY
- A Pilot Clinical Study of Treatment Guided by Personalized Tumorgrafts in Patients with Advanced Cancer
- (2011) M. Hidalgo et al. MOLECULAR CANCER THERAPEUTICS
- Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung
- (2011) T. Willinger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional CD47/signal regulatory protein alpha (SIRPα) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo
- (2011) Nicolas Legrand et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transgenic expression of human signal regulatory protein alpha in Rag2−/−γc−/−mice improves engraftment of human hematopoietic cells in humanized mice
- (2011) Till Strowig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Parameters for establishing humanized mouse models to study human immunity: Analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rγnull mutation
- (2010) Michael A. Brehm et al. CLINICAL IMMUNOLOGY
- The IL-7 Signaling Pathway Regulates Lymph Node Development Independent of Peripheral Lymphocytes
- (2010) S. Chappaz et al. JOURNAL OF IMMUNOLOGY
- The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
- (2010) Taro Kawai et al. NATURE IMMUNOLOGY
- Humanized Mice for Modeling Human Infectious Disease: Challenges, Progress, and Outlook
- (2009) Nicolas Legrand et al. Cell Host & Microbe
- Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells
- (2009) Donghui Zhang et al. CELL RESEARCH
- Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex
- (2009) M. A. King et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- The analysis of the functions of human B and T cells in humanized NOD/shi-scid/γcnull (NOG) mice (hu-HSC NOG mice)
- (2009) Yohei Watanabe et al. INTERNATIONAL IMMUNOLOGY
- CXCL13 expression in the gut promotes accumulation of IL-22-producing lymphoid tissue-inducer cells and formation of isolated lymphoid follicles
- (2009) F Marchesi et al. Mucosal Immunology
- The nuances of therapy
- (2009) Lee M. Ellis et al. NATURE
- Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation
- (2009) Serge A van de Pavert et al. NATURE IMMUNOLOGY
- Generation of pluripotent stem cells from patients with type 1 diabetes
- (2009) R. Maehr et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Highly Sensitive Model for Xenogenic GVHD Using Severe Immunodeficient NOG Mice
- (2009) Ryoji Ito et al. TRANSPLANTATION
- Non-obese diabetic-recombination activating gene-1 (NOD-Rag 1null) interleukin (IL)-2 receptor common gamma chain (IL 2 rγnull) null mice: a radioresistant model for human lymphohaematopoietic engraftment
- (2008) T. Pearson et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- IL-15 trans-presentation promotes human NK cell development and differentiation in vivo
- (2008) Nicholas D. Huntington et al. JOURNAL OF EXPERIMENTAL MEDICINE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now