Haematopoietic stem and progenitor cells from human pluripotent stem cells

Directed differentiation of definitive hemogenic endothelium and hematopoietic progenitors from human pluripotent stem cells

(2016) Andrea Ditadi et al.   METHODS

Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros

(2016) Elizabeth S Ng et al.   NATURE BIOTECHNOLOGY

Medial HOXA genes demarcate haematopoietic stem cell fate during human development

(2016) Diana R. Dou et al.   NATURE CELL BIOLOGY

Droplet Barcoding for Single-Cell Transcriptomics Applied to Embryonic Stem Cells

(2015) Allon M. Klein et al.   CELL

Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages

(2015) Andrea Ditadi et al.   NATURE CELL BIOLOGY

Long non-coding RNA profiling of human lymphoid progenitor cells reveals transcriptional divergence of B cell and T cell lineages

(2015) David Casero et al.   NATURE IMMUNOLOGY

Distinct routes of lineage development reshape the human blood hierarchy across ontogeny

(2015) F. Notta et al.   SCIENCE

The RUNX1 +24 Enhancer and P1 Promoter Identify a Unique Subpopulation of Hematopoietic Progenitor Cells Derived from Human Pluripotent Stem Cells

(2015) Patrick I. Ferrell et al.   STEM CELLS

Nonirradiated NOD,B6.SCID Il2rγ−/− KitW41/W41 (NBSGW) Mice Support Multilineage Engraftment of Human Hematopoietic Cells

(2015) Brian E. McIntosh et al.   Stem Cell Reports

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

An RCOR1 loss-associated gene expression signature identifies a prognostically significant DLBCL subgroup

(2014) F. C. Chan et al.   BLOOD

CellNet: Network Biology Applied to Stem Cell Engineering

(2014) Patrick Cahan et al.   CELL

Reprogramming Committed Murine Blood Cells to Induced Hematopoietic Stem Cells with Defined Factors

(2014) Jonah Riddell et al.   CELL

Reprogramming human endothelial cells to haematopoietic cells requires vascular induction

(2014) Vladislav M. Sandler et al.   NATURE

Direct induction of haematoendothelial programs in human pluripotent stem cells by transcriptional regulators

(2014) Irina Elcheva et al.   Nature Communications

Direct Reprogramming of Murine Fibroblasts to Hematopoietic Progenitor Cells

(2014) Kiran Batta et al.   Cell Reports

Induction of a Hemogenic Program in Mouse Fibroblasts

(2013) Carlos-Filipe Pereira et al.   Cell Stem Cell

Induction of Multipotential Hematopoietic Progenitors from Human Pluripotent Stem Cells via Respecification of Lineage-Restricted Precursors

(2013) Sergei Doulatov et al.   Cell Stem Cell

The transcriptional architecture of early human hematopoiesis identifies multilevel control of lymphoid commitment

(2013) Elisa Laurenti et al.   NATURE IMMUNOLOGY

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

T Lymphocyte Potential Marks the Emergence of Definitive Hematopoietic Progenitors in Human Pluripotent Stem Cell Differentiation Cultures

(2012) Marion Kennedy et al.   Cell Reports

 4 integrin levels on mobilized peripheral blood stem cells predict rapidity of engraftment in patients receiving autologous stem cell transplantation

(2011) B. Hartz et al.   BLOOD

Identification and characterization of Hoxa9 binding sites in hematopoietic cells

(2011) Y. Huang et al.   BLOOD

RUNX1 regulates corepressor interactions of PU.1

(2011) Z. Hu et al.   BLOOD

The host genomic environment of the provirus determines the abundance of HTLV-1-infected T-cell clones

(2011) N. A. Gillet et al.   BLOOD

Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis

(2011) Noa Novershtern et al.   CELL

Robo4 Cooperates with Cxcr4 to Specify Hematopoietic Stem Cell Localization to Bone Marrow Niches

(2011) Stephanie Smith-Berdan et al.   Cell Stem Cell

Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros region

(2011) Andrejs Ivanovs et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo

(2011) Kristen L. Meerbrey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reprogramming of T Cells from Human Peripheral Blood

(2010) Yuin-Han Loh et al.   Cell Stem Cell

Additive and global functions of HoxA cluster genes in mesoderm derivatives

(2010) Nicolas Di-Poï et al.   DEVELOPMENTAL BIOLOGY

Direct conversion of human fibroblasts to multilineage blood progenitors

(2010) Eva Szabo et al.   NATURE

In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium

(2010) Jean-Charles Boisset et al.   NATURE

Haematopoietic stem cells derive directly from aortic endothelium during development

(2010) Julien Y. Bertrand et al.   NATURE

Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development

(2010) Sergei Doulatov et al.   NATURE IMMUNOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Trisomy of Erg is required for myeloproliferation in a mouse model of Down syndrome

(2009) A. P. Ng et al.   BLOOD

Developmental and species-divergent globin switching are driven by BCL11A

(2009) Vijay G. Sankaran et al.   NATURE

The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells

(2008) Stephen J Loughran et al.   NATURE IMMUNOLOGY

Of lineage and legacy: the development of mammalian hematopoietic stem cells

(2008) Elaine Dzierzak et al.   NATURE IMMUNOLOGY