Islet-Specific CTL Cloned from a Type 1 Diabetes Patient Cause Beta-Cell Destruction after Engraftment into HLA-A2 Transgenic NOD/SCID/IL2RG Null Mice

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

(2012) Ken T. Coppieters et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Prevention of "Humanized" Diabetogenic CD8 T-Cell Responses in HLA-Transgenic NOD Mice by a Multipeptide Coupled-Cell Approach

(2011) M. Niens et al.   DIABETES

HLA-A2-Matched Peripheral Blood Mononuclear Cells From Type 1 Diabetic Patients, but Not Nondiabetic Donors, Transfer Insulitis to NOD-scid/ cnull/HLA-A2 Transgenic Mice Concurrent With the Expansion of Islet-Specific CD8+ T cells

(2011) F. Whitfield-Larry et al.   DIABETES

Islet inflammation and CXCL10 in recent-onset type 1 diabetes

(2010) B. O. Roep et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

T Cell Islet Accumulation in Type 1 Diabetes Is a Tightly Regulated, Cell-Autonomous Event

(2009) Greig P. Lennon et al.   IMMUNITY

Priming of protective T cell responses against virus-induced tumors in mice with human immune system components

(2009) Till Strowig et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD8+ T lymphocyte mobilization to virus-infected tissue requires CD4+ T-cell help

(2009) Yusuke Nakanishi et al.   NATURE

Dengue Virus Infection and Virus-Specific HLA-A2 Restricted Immune Responses in Humanized NOD-scid IL2rγnull Mice

(2009) Smita Jaiswal et al.   PLoS One

Identification of novel IGRP epitopes targeted in type 1 diabetes patients

(2008) Irene Jarchum et al.   CLINICAL IMMUNOLOGY

Weak Proinsulin Peptide-Major Histocompatibility Complexes Are Targeted in Autoimmune Diabetes in Mice

(2008) M. G. Levisetti et al.   DIABETES

Accumulation of autoreactive effector T cells and allo-specific regulatory T cells in the pancreas allograft of a type 1 diabetic recipient

(2008) J. H. Velthuis et al.   DIABETOLOGIA

Restoring the Association of the T Cell Receptor with CD8 Reverses Anergy in Human Tumor-Infiltrating Lymphocytes

(2008) Nathalie Demotte et al.   IMMUNITY

A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene

(2007) Marie King et al.   CLINICAL IMMUNOLOGY