Altered Energy Metabolism Pathways in the Posterior Cingulate in Young Adult Apolipoprotein E ɛ4 Carriers

The Alzheimer's Disease Mitochondrial Cascade Hypothesis

(2017) Russell H. Swerdlow et al.   JOURNAL OF ALZHEIMERS DISEASE

Rethinking Alzheimer's Disease Therapy: Are Mitochondria the Key?

(2017) Maria Ankarcrona et al.   JOURNAL OF ALZHEIMERS DISEASE

Reduced Posterior Cingulate Mitochondrial Activity in Expired Young Adult Carriers of the APOE ε4 Allele, the Major Late-Onset Alzheimer's Susceptibility Gene

(2017) Jon Valla et al.   JOURNAL OF ALZHEIMERS DISEASE

Effects of ketone bodies in Alzheimer's disease in relation to neural hypometabolism, β-amyloid toxicity, and astrocyte function

(2015) Leif Hertz et al.   JOURNAL OF NEUROCHEMISTRY

GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration

(2015) Ethan A Winkler et al.   NATURE NEUROSCIENCE

Alzheimer's disease is associated with altered expression of genes involved in immune response and mitochondrial processes in astrocytes

(2015) Shobana Sekar et al.   NEUROBIOLOGY OF AGING

Changes in lactate content and monocarboxylate transporter 2 expression in Aβ25-35-treated rat model of Alzheimer’s disease

(2015) Weitian Lu et al.   NEUROLOGICAL SCIENCES

A Cellular Perspective on Brain Energy Metabolism and Functional Imaging

(2015) Pierre J. Magistretti et al.   NEURON

Human Apolipoprotein E ε4 Expression Impairs Cerebral Vascularization and Blood—Brain Barrier Function in Mice

(2014) Wael Alata et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

APOE genotype and neuroimaging markers of Alzheimer's disease: systematic review and meta-analysis

(2014) Y. Liu et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Apolipoprotein E in Synaptic Plasticity and Alzheimer’s Disease: Potential Cellular and Molecular Mechanisms

(2014) Jaekwang Kim et al.   MOLECULES AND CELLS

ApoE and Aβ in Alzheimer’s Disease: Accidental Encounters or Partners?

(2014) Takahisa Kanekiyo et al.   NEURON

Glucose transporter 3 is a rab11-dependent trafficking cargo and its transport to the cell surface is reduced in neurons of CAG140 Huntington’s disease mice

(2014) Hollis McClory et al.   Acta Neuropathologica Communications

The role of the posterior cingulate cortex in cognition and disease

(2013) Robert Leech et al.   BRAIN

Bioenergetic medicine

(2013) Russell H Swerdlow   BRITISH JOURNAL OF PHARMACOLOGY

Common Variants in Psychiatric Risk Genes Predict Brain Structure at Birth

(2013) R. C. Knickmeyer et al.   CEREBRAL CORTEX

Energetic cost of brain functional connectivity

(2013) D. Tomasi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apolipoprotein E as a β-amyloid-independent factor in Alzheimer’s disease

(2013) Andrew B Wolf et al.   Alzheimers Research & Therapy

Cerebrovascular Effects of Apolipoprotein E

(2013) Berislav V. Zlokovic   JAMA Neurology

Brain Differences in Infants at Differential Genetic Risk for Late-Onset Alzheimer Disease

(2013) Douglas C. Dean et al.   JAMA Neurology

Overexpression of Pyruvate Dehydrogenase Kinase 1 and Lactate Dehydrogenase A in Nerve Cells Confers Resistance to Amyloid β and Other Toxins by Decreasing Mitochondrial Respiration and Reactive Oxygen Species Production

(2012) Jordan T. Newington et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ketone bodies in epilepsy

(2012) Melanie A. McNally et al.   JOURNAL OF NEUROCHEMISTRY

Apolipoprotein E, Not Fibrillar  -Amyloid, Reduces Cerebral Glucose Metabolism in Normal Aging

(2012) W. J. Jagust et al.   JOURNAL OF NEUROSCIENCE

APOE and neuroenergetics: an emerging paradigm in Alzheimer's disease

(2012) Andrew B. Wolf et al.   NEUROBIOLOGY OF AGING

Apolipoprotein E Sets the Stage: Response to Injury Triggers Neuropathology

(2012) Robert W. Mahley et al.   NEURON

Association and Expression Analyses With Single-Nucleotide Polymorphisms in TOMM40 in Alzheimer Disease

(2011) Carlos Cruchaga   ARCHIVES OF NEUROLOGY

Roles of apolipoprotein E4 (ApoE4) in the pathogenesis of Alzheimer's disease: lessons from ApoE mouse models

(2011) Yadong Huang   BIOCHEMICAL SOCIETY TRANSACTIONS

PET amyloid-beta imaging in preclinical Alzheimer's disease

(2011) Andrei G. Vlassenko et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Activity-Dependent Regulation of Surface Glucose Transporter-3

(2011) J. M. Ferreira et al.   JOURNAL OF NEUROSCIENCE

Brain imaging in the study of Alzheimer's disease

(2011) Eric M. Reiman et al.   NEUROIMAGE

Worldwide allele frequencies of the human apolipoprotein E gene: Climate, local adaptations, and evolutionary history

(2010) Dan T.A. Eisenberg et al.   AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY

Brain Glucose Hypometabolism and Oxidative Stress in Preclinical Alzheimer's Disease

(2010) Lisa Mosconi et al.   Annals of the New York Academy of Sciences

An Inherited Variable Poly-T Repeat Genotype in TOMM40 in Alzheimer Disease

(2010) Allen D. Roses   ARCHIVES OF NEUROLOGY

Regional cerebral glucose uptake in the 3xTG model of Alzheimer's disease highlights common regional vulnerability across AD mouse models

(2010) Rachel M. Nicholson et al.   BRAIN RESEARCH

No association of psychosis in Alzheimer disease with neurodegenerative pathway genes

(2010) Mary Ann A. DeMichele-Sweet et al.   NEUROBIOLOGY OF AGING

The effects of APOE-ε4 on the BOLD response

(2010) Aaron J. Trachtenberg et al.   NEUROBIOLOGY OF AGING

Beneficial network effects of methylene blue in an amnestic model

(2010) Penny D. Riha et al.   NEUROIMAGE

Spatial correlation between brain aerobic glycolysis and amyloid-β (Aβ) deposition

(2010) Andrei G. Vlassenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regional aerobic glycolysis in the human brain

(2010) S. Neil Vaishnavi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aβ-independent roles of apolipoprotein E4 in the pathogenesis of Alzheimer's disease

(2010) Yadong Huang   TRENDS IN MOLECULAR MEDICINE

Apolipoprotein E4 Domain Interaction Induces Endoplasmic Reticulum Stress and Impairs Astrocyte Function

(2009) Ning Zhong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ApoE4 Decreases Spine Density and Dendritic Complexity in Cortical Neurons In Vivo

(2009) S. B. Dumanis et al.   JOURNAL OF NEUROSCIENCE

Basal Cerebral Metabolism May Modulate the Cognitive Effects of A  in Mild Cognitive Impairment: An Example of Brain Reserve

(2009) A. D. Cohen et al.   JOURNAL OF NEUROSCIENCE

Apolipoprotein E4 (1–272) fragment is associated with mitochondrial proteins and affects mitochondrial function in neuronal cells

(2009) Toshiyuki Nakamura et al.   Molecular Neurodegeneration

The Role of Apolipoprotein E in Alzheimer's Disease

(2009) Jungsu Kim et al.   NEURON

Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial

(2009) Samuel T Henderson et al.   Nutrition & Metabolism

A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease

(2009) A D Roses et al.   PHARMACOGENOMICS JOURNAL

The Brain's Default Network

(2008) Randy L. Buckner et al.   Annals of the New York Academy of Sciences

Understanding the Association of Apolipoprotein E4 with Alzheimer Disease: Clues from Its Structure

(2008) Ning Zhong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apolipoprotein E knock-out and knock-in mice: atherosclerosis, metabolic syndrome, and beyond: Fig. 1.

(2008) Avani A. Pendse et al.   JOURNAL OF LIPID RESEARCH

Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses

(2008) Lars Bertram et al.   NATURE REVIEWS NEUROSCIENCE

Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons

(2008) W. S. Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA