Is Retinal Metabolic Dysfunction at the Center of the Pathogenesis of Age-related Macular Degeneration?
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Title
Is Retinal Metabolic Dysfunction at the Center of the Pathogenesis of Age-related Macular Degeneration?
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 3, Pages 762
Publisher
MDPI AG
Online
2019-02-12
DOI
10.3390/ijms20030762
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Note: Only part of the references are listed.- Biochemistry of proinflammatory macrophage activation
- (2018) Yannic Nonnenmacher et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Elusive drusen and changing terminology of AMD
- (2018) P. T. V. M. De Jong EYE
- THE ROLE OF METABOLIC REMODELING IN MACROPHAGE POLARIZATION AND ITS EFFECT ON SKELETAL MUSCLE REGENERATION
- (2018) Francesca De Santa et al. ANTIOXIDANTS & REDOX SIGNALING
- Monocarboxylate Transporter 4 (MCT4) Knockout Mice Have Attenuated 4NQO Induced Carcinogenesis; A Role for MCT4 in Driving Oral Squamous Cell Cancer
- (2018) Sara Bisetto et al. Frontiers in Oncology
- Complement Factor H Inhibits CD47-Mediated Resolution of Inflammation
- (2017) Bertrand Calippe et al. IMMUNITY
- Mathematical models of retinitis pigmentosa: The oxygen toxicity hypothesis
- (2017) Paul A. Roberts et al. JOURNAL OF THEORETICAL BIOLOGY
- Cell Signaling with Extracellular Thioredoxin and Thioredoxin-Like Proteins: Insight into Their Mechanisms of Action
- (2017) Thierry Léveillard et al. Oxidative Medicine and Cellular Longevity
- Gpr132 sensing of lactate mediates tumor–macrophage interplay to promote breast cancer metastasis
- (2017) Peiwen Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD
- (2017) Sayantan Datta et al. PROGRESS IN RETINAL AND EYE RESEARCH
- On phagocytes and macular degeneration
- (2017) Xavier Guillonneau et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye
- (2017) Mark A Kanow et al. eLife
- Glycolytic reliance promotes anabolism in photoreceptors
- (2017) Yashodhan Chinchore et al. eLife
- Activated monocytes resist elimination by retinal pigment epithelium and downregulate their OTX2 expression via TNF-α
- (2016) Thibaud Mathis et al. AGING CELL
- The Thioredoxin Encoded by the Rod-Derived Cone Viability Factor Gene Protects Cone Photoreceptors Against Oxidative Stress
- (2016) Xin Mei et al. ANTIOXIDANTS & REDOX SIGNALING
- Mathematical Model of the Role of RdCVF in the Coexistence of Rods and Cones in a Healthy Eye
- (2016) Erika T. Camacho et al. BULLETIN OF MATHEMATICAL BIOLOGY
- Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation
- (2016) Vicky Lampropoulou et al. Cell Metabolism
- Metabolic and redox signaling in the retina
- (2016) Thierry Léveillard et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- It is all about fluidity: Fatty acids and macrophage phagocytosis
- (2016) Julia Schumann EUROPEAN JOURNAL OF PHARMACOLOGY
- Structural and molecular changes in the aging choroid: implications for age-related macular degeneration
- (2016) K R Chirco et al. EYE
- Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels
- (2016) Thekla Cordes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fatty acid synthesis configures the plasma membrane for inflammation in diabetes
- (2016) Xiaochao Wei et al. NATURE
- Delayed Rod-Mediated Dark Adaptation Is a Functional Biomarker for Incident Early Age-Related Macular Degeneration
- (2016) Cynthia Owsley et al. OPHTHALMOLOGY
- Activation of oncogenic tyrosine kinase signaling promotes insulin receptor-mediated cone photoreceptor survival
- (2016) Ammaji Rajala et al. Oncotarget
- Two-Step Reactivation of Dormant Cones in Retinitis Pigmentosa
- (2016) Wei Wang et al. Cell Reports
- Subretinal mononuclear phagocytes induce cone segment loss via IL-1β
- (2016) Chiara M Eandi et al. eLife
- Rod-Derived Cone Viability Factor Promotes Cone Survival by Stimulating Aerobic Glycolysis
- (2015) Najate Aït-Ali et al. CELL
- Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
- (2015) Eva M. Palsson-McDermott et al. Cell Metabolism
- Metabolic reprogramming in macrophages and dendritic cells in innate immunity
- (2015) Beth Kelly et al. CELL RESEARCH
- Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration
- (2015) O. Levy et al. EMBO Molecular Medicine
- Mitochondria in the Regulation of Innate and Adaptive Immunity
- (2015) Samuel E. Weinberg et al. IMMUNITY
- Upregulation of P2RX7 in Cx3cr1-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1 Secretion and Photoreceptor Neurodegeneration
- (2015) S. J. Hu et al. JOURNAL OF NEUROSCIENCE
- APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration
- (2015) Olivier Levy et al. JOURNAL OF NEUROSCIENCE
- A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants
- (2015) Lars G Fritsche et al. NATURE GENETICS
- Impairments in Dark Adaptation Are Associated with Age-Related Macular Degeneration Severity and Reticular Pseudodrusen
- (2015) Jason Flamendorf et al. OPHTHALMOLOGY
- Contribution of metabolic reprogramming to macrophage plasticity and function
- (2015) Karim C. EL Kasmi et al. SEMINARS IN IMMUNOLOGY
- Cancer metabolism of cone photoreceptors
- (2015) Thierry Léveillard Oncotarget
- Spontaneous Regeneration of Human Photoreceptor Outer Segments
- (2015) Jonathan C. Horton et al. Scientific Reports
- Current knowledge on reticular pseudodrusen in age-related macular degeneration
- (2014) F Alten et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Complement factor H and related proteins in age-related macular degeneration
- (2014) Bertrand Calippe et al. COMPTES RENDUS BIOLOGIES
- Plasma membrane protein polarity and trafficking in RPE cells: Past, present and future
- (2014) Guillermo L. Lehmann et al. EXPERIMENTAL EYE RESEARCH
- The Monocarboxylate Transporter 4 Is Required for Glycolytic Reprogramming and Inflammatory Response in Macrophages
- (2014) Zheng Tan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Geographic Atrophy
- (2014) Alan C. Bird et al. JAMA Ophthalmology
- Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages
- (2014) Meera Rath et al. Frontiers in Immunology
- Local apoptosis mediates clearance of macrophages from resolving inflammation in mice
- (2013) E. L. Gautier et al. BLOOD
- CCR2+monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation inCx3cr1deficient mice
- (2013) Florian Sennlaub et al. EMBO Molecular Medicine
- The thioredoxin antioxidant system
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- The familial dementia gene revisited: a missense mutation revealed by whole-exome sequencing identifies ITM2B as a candidate gene underlying a novel autosomal dominant retinal dystrophy in a large family
- (2013) Isabelle Audo et al. HUMAN MOLECULAR GENETICS
- Photoreceptor Proteins Initiate Microglial Activation via Toll-like Receptor 4 in Retinal Degeneration Mediated by All-trans-retinal
- (2013) Hideo Kohno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Small interfering RNA-mediated suppression of Ccl2 in Müller cells attenuates microglial recruitment and photoreceptor death following retinal degeneration
- (2013) Matt Rutar et al. Journal of Neuroinflammation
- Macrophage biology in development, homeostasis and disease
- (2013) Thomas A. Wynn et al. NATURE
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
- (2013) G. M. Tannahill et al. NATURE
- Seven new loci associated with age-related macular degeneration
- (2013) Lars G Fritsche et al. NATURE GENETICS
- Seven-Year Outcomes in Ranibizumab-Treated Patients in ANCHOR, MARINA, and HORIZON
- (2013) Soraya Rofagha et al. OPHTHALMOLOGY
- Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production
- (2013) A. Michelucci et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aging is not a disease: Distinguishing age-related macular degeneration from aging
- (2013) Daniel Ardeljan et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Nitric Oxide Regulates Mitochondrial Fatty Acid Metabolism Through Reversible Protein S-Nitrosylation
- (2013) P.-T. Doulias et al. Science Signaling
- Photoreceptor Impairment and Restoration on Optical Coherence Tomographic Image
- (2013) Yoshinori Mitamura et al. Journal of Ophthalmology
- Chronic photo-oxidative stress and subsequent MCP-1 activation as causative factors for age-related macular degeneration
- (2012) M. Suzuki et al. JOURNAL OF CELL SCIENCE
- Interleukin-1β Inhibition Prevents Choroidal Neovascularization and Does Not Exacerbate Photoreceptor Degeneration
- (2011) Sophie Lavalette et al. AMERICAN JOURNAL OF PATHOLOGY
- Stomatin-deficient cryohydrocytosis results from mutations in SLC2A1: a novel form of GLUT1 deficiency syndrome
- (2011) J. F. Flatt et al. BLOOD
- Retinal pigment epithelial expression of complement regulator CD46 is altered early in the course of geographic atrophy
- (2011) Susan D. Vogt et al. EXPERIMENTAL EYE RESEARCH
- Evidence of association ofAPOEwith age-related macular degeneration - a pooled analysis of 15 studies
- (2011) Gareth J. McKay et al. HUMAN MUTATION
- Monocyte Chemoattractant Protein 1, Intercellular Adhesion Molecule 1, and Vascular Cell Adhesion Molecule 1 in Exudative Age-Related Macular Degeneration
- (2010) Jost B. Jonas ARCHIVES OF OPHTHALMOLOGY
- Nonresolving Inflammation
- (2010) Carl Nathan et al. CELL
- Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa
- (2010) V. Busskamp et al. SCIENCE
- Translating NO Biology into Clinical Advances
- (2009) Lester Kobzik AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Bruch's membrane and choroidal macrophages in early and advanced age-related macular degeneration
- (2009) S. Cherepanoff et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- The Thioredoxin-like Protein Rod-derived Cone Viability Factor (RdCVFL) Interacts with TAU and Inhibits Its Phosphorylation in the Retina
- (2009) Ram Fridlich et al. MOLECULAR & CELLULAR PROTEOMICS
- Reticular Pseudodrusen Are Subretinal Drusenoid Deposits
- (2009) Sandrine A. Zweifel et al. OPHTHALMOLOGY
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Altered visual function in monocarboxylate transporter 3 (Slc16a8) knockout mice
- (2008) Lauren L. Daniele et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Suppressors of Cytokine-Signaling Proteins Induce Insulin Resistance in the Retina and Promote Survival of Retinal Cells
- (2008) X. Liu et al. DIABETES
- Sub-retinal drusenoid deposits in human retina: Organization and composition
- (2008) Martin Rudolf et al. EXPERIMENTAL EYE RESEARCH
- Origin and physiological roles of inflammation
- (2008) Ruslan Medzhitov NATURE
- The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis
- (2008) Przemyslaw Sapieha et al. NATURE MEDICINE
- Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa
- (2008) Claudio Punzo et al. NATURE NEUROSCIENCE
- The Epidemiology of Retinal Reticular Drusen
- (2007) Ronald Klein et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
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