Gpr132 sensing of lactate mediates tumor–macrophage interplay to promote breast cancer metastasis

Activatable Water-Soluble Probes Enhance Tumor Imaging by Responding to Dysregulated pH and Exhibiting High Tumor-to-Liver Fluorescence Emission Contrast

(2016) Hu Xiong et al.   BIOCONJUGATE CHEMISTRY

Ligand Activation of ERRα by Cholesterol Mediates Statin and Bisphosphonate Effects

(2016) Wei Wei et al.   Cell Metabolism

Mitochondrial dysfunction remodels one-carbon metabolism in human cells

(2016) Xiaoyan Robert Bao et al.   eLife

Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer

(2015) C. N. Johnstone et al.   Disease Models & Mechanisms

F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner

(2015) Kanae Yumimoto et al.   JOURNAL OF CLINICAL INVESTIGATION

CCL2-induced chemokine cascade promotes breast cancer metastasis by enhancing retention of metastasis-associated macrophages

(2015) Takanori Kitamura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Collagen VI regulates peripheral nerve regeneration by modulating macrophage recruitment and polarization

(2014) Peiwen Chen et al.   ACTA NEUROPATHOLOGICA

A Positive Feedback Loop between Mesenchymal-like Cancer Cells and Macrophages Is Essential to Breast Cancer Metastasis

(2014) Shicheng Su et al.   CANCER CELL

Cell Surface Lactate Receptor GPR81 Is Crucial for Cancer Cell Survival

(2014) C. L. Roland et al.   CANCER RESEARCH

Effect of miR-142-3p on the M2 Macrophage and Therapeutic Efficacy Against Murine Glioblastoma

(2014) Shuo Xu et al.   JNCI-Journal of the National Cancer Institute

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

(2014) Oscar R. Colegio et al.   NATURE

Characterization of murine macrophages from bone marrow, spleen and peritoneum

(2013) Changqi Wang et al.   BMC IMMUNOLOGY

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

(2013) Stephanie M Pyonteck et al.   NATURE MEDICINE

Modulation of macrophage phenotype by cell shape

(2013) F. Y. McWhorter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acidic tumor microenvironment and pH-sensing G protein-coupled receptors

(2013) Calvin R. Justus et al.   Frontiers in Physiology

Stromal cells in tumor microenvironment and breast cancer

(2012) Yan Mao et al.   CANCER AND METASTASIS REVIEWS

A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis

(2012) Swarnali Acharyya et al.   CELL

Autocrine and paracrine loops between cancer cells and macrophages promote lymph node metastasisviaCCR4/CCL22 in head and neck squamous cell carcinoma

(2012) Takahiro Tsujikawa et al.   INTERNATIONAL JOURNAL OF CANCER

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

A positive/negative ion–switching, targeted mass spectrometry–based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue

(2012) Min Yuan et al.   Nature Protocols

CCL18 from Tumor-Associated Macrophages Promotes Breast Cancer Metastasis via PITPNM3

(2011) Jingqi Chen et al.   CANCER CELL

PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target

(2011) Jiarong Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation

(2011) C. C.-L. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

An Autocrine Lactate Loop Mediates Insulin-Dependent Inhibition of Lipolysis through GPR81

(2010) Kashan Ahmed et al.   Cell Metabolism

Review: Hydroxyoctadecadienoic acids: novel regulators of macrophage differentiation and atherogenesis

(2010) Venkat Vangaveti et al.   Therapeutic Advances in Endocrinology and Metabolism

ApoE-Dependent Modulation of HDL and Atherosclerosis by G2A in LDL Receptor–Deficient Mice Independent of Bone Marrow–Derived Cells

(2009) Brian W. Parks et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

PrognoScan: a new database for meta-analysis of the prognostic value of genes

(2009) Hideaki Mizuno et al.   BMC Medical Genomics

G2A and LPC: Regulatory functions in immunity

(2009) Janusz H. Kabarowski   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Heterogeneity of Human Macrophages in Culture and in Atherosclerotic Plaques

(2008) Stephen W. Waldo et al.   AMERICAN JOURNAL OF PATHOLOGY

G2A Deficiency in Mice Promotes Macrophage Activation and Atherosclerosis

(2008) David T. Bolick et al.   CIRCULATION RESEARCH

Metastatic Breast Cancer: The Treatment Challenge

(2008) Stephen E. Jones   Clinical Breast Cancer

Lactate Inhibits Lipolysis in Fat Cells through Activation of an Orphan G-protein-coupled Receptor, GPR81

(2008) Changlu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY