Monocarboxylate Transporter 4 (MCT4) Knockout Mice Have Attenuated 4NQO Induced Carcinogenesis; A Role for MCT4 in Driving Oral Squamous Cell Cancer

MCT4 Expression Is a Potential Therapeutic Target in Colorectal Cancer with Peritoneal Carcinomatosis

(2018) Hee Kyung Kim et al.   MOLECULAR CANCER THERAPEUTICS

Mitochondrial and glycolytic metabolic compartmentalization in diffuse large B-cell lymphoma

(2017) Mahasweta Gooptu et al.   SEMINARS IN ONCOLOGY

Metabolic coupling and the Reverse Warburg Effect in cancer: Implications for novel biomarker and anticancer agent development

(2017) Lindsay Wilde et al.   SEMINARS IN ONCOLOGY

Regulatory T cells function at the early stage of tumor progression in a mouse model of tongue squamous cell carcinoma

(2016) Kentaro Miki et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Reexamining cancer metabolism: lactate production for carcinogenesis could be the purpose and explanation of the Warburg Effect

(2016) Iñigo San-Millán et al.   CARCINOGENESIS

Prognostic significance of monocarboxylate transporter expression in oral cavity tumors

(2016) Susana Simões-Sousa et al.   CELL CYCLE

The metabolic microenvironment of melanomas: Prognostic value of MCT1 and MCT4

(2016) Céline Pinheiro et al.   CELL CYCLE

TP53-inducible Glycolysis and Apoptosis Regulator (TIGAR) Metabolically Reprograms Carcinoma and Stromal Cells in Breast Cancer

(2016) Ying-Hui Ko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive Proteomics Analysis Reveals Metabolic Reprogramming of Tumor-Associated Macrophages Stimulated by the Tumor Microenvironment

(2016) Di Liu et al.   JOURNAL OF PROTEOME RESEARCH

Monocarboxylate Transporters MCT1 and MCT4 Regulate Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells

(2016) Su Chii Kong et al.   PANCREAS

Functional screening identifies MCT4 as a key regulator of breast cancer cell metabolism and survival

(2015) Franziska Baenke et al.   JOURNAL OF PATHOLOGY

Prognostic Indications of Elevated MCT4 and CD147 across Cancer Types: A Meta-Analysis

(2015) Cory D. Bovenzi et al.   Biomed Research International

The cross-talk between NF-κB and HIF-1: further evidence for a significant liaison: Figure 1

(2015) Agnes Görlach et al.   BIOCHEMICAL JOURNAL

Expression of the hypoxia-inducible monocarboxylate transporter MCT4 is increased in triple negative breast cancer and correlates independently with clinical outcome

(2014) J. Doyen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genetic Disruption of Lactate/H+ Symporters (MCTs) and Their Subunit CD147/BASIGIN Sensitizes Glycolytic Tumor Cells to Phenformin

(2014) I. Marchiq et al.   CANCER RESEARCH

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

The Monocarboxylate Transporter 4 Is Required for Glycolytic Reprogramming and Inflammatory Response in Macrophages

(2014) Zheng Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A reverse Warburg metabolism in oral squamous cell carcinoma is not dependent upon myofibroblasts

(2014) David H. Jensen et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Monocarboxylate Transporter 4 Facilitates Cell Proliferation and Migration and Is Associated with Poor Prognosis in Oral Squamous Cell Carcinoma Patients

(2014) Jiang Zhu et al.   PLoS One

Current Management of Locally Advanced Head and Neck Cancer: The Combination of Chemotherapy With Locoregional Treatments

(2014) Voichita Bar-Ad et al.   SEMINARS IN ONCOLOGY

Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis

(2013) J. R. Doherty et al.   CANCER RESEARCH

The molecular features of tongue epithelium treated with the carcinogen 4-nitroquinoline-1-oxide and alcohol as a model for HNSCC

(2013) K. Osei-Sarfo et al.   CARCINOGENESIS

Cancer metabolism, stemness and tumor recurrence

(2013) Joseph M. Curry et al.   CELL CYCLE

Targeting lactate metabolism for cancer therapeutics

(2013) Joanne R. Doherty et al.   JOURNAL OF CLINICAL INVESTIGATION

Endothelial cell metabolism and tumour angiogenesis: glucose and glutamine as essential fuels and lactate as the driving force

(2013) F. Polet et al.   JOURNAL OF INTERNAL MEDICINE

Lactate enhances motility of tumor cells and inhibits monocyte migration and cytokine release

(2011) Kristina Goetze   INTERNATIONAL JOURNAL OF ONCOLOGY

Regulation of mTORC1 Signaling by pH

(2011) Aruna D. Balgi et al.   PLoS One

Lactate downregulates the glycolytic enzymes hexokinase and phosphofructokinase in diverse tissues from mice

(2010) Tiago C. Leite et al.   FEBS LETTERS

Regulation of hypoxia-inducible factor-1α by NF-κB

(2008) Patrick van Uden et al.   BIOCHEMICAL JOURNAL

Role of the NF-κB transcriptome and proteome as biomarkers in human head and neck squamous cell carcinomas

(2008) Zhong Chen et al.   Biomarkers in Medicine