Extracellular vesicles in liver disease and beyond

Extracellular vesicles from mice with alcoholic liver disease carry a distinct protein cargo and induce macrophage activation through heat shock protein 90

(2018) Banishree Saha et al.   HEPATOLOGY

Extracellular vesicles: Novel mediator for cell to cell communications in liver pathogenesis

(2018) Pradip B. Devhare et al.   MOLECULAR ASPECTS OF MEDICINE

Extracellular vesicles in neurodegenerative diseases

(2018) Tommaso Croese et al.   MOLECULAR ASPECTS OF MEDICINE

Extracellular vesicles as potential biomarkers for alcohol- and drug-induced liver injury and their therapeutic applications

(2018) Young-Eun Cho et al.   PHARMACOLOGY & THERAPEUTICS

Priming of dendritic cells by DNA-containing extracellular vesicles from activated T cells through antigen-driven contacts

(2018) Daniel Torralba et al.   Nature Communications

Hepatitis C virus-induced CCL5 secretion from macrophages activates hepatic stellate cells

(2017) Reina Sasaki et al.   HEPATOLOGY

Extracellular vesicles in liver disease and potential as biomarkers and therapeutic targets

(2017) Gyongyi Szabo et al.   Nature Reviews Gastroenterology & Hepatology

Extracellular Vesicles in Cardiovascular Theranostics

(2017) Yihua Bei et al.   Theranostics

Functional Roles and Therapeutic Applications of Exosomes in Hepatocellular Carcinoma

(2017) Laura Santangelo et al.   Biomed Research International

Pathways of production and delivery of hepatocyte exosomes

(2017) Li Chen et al.   Journal of Cell Communication and Signaling

Hepatocyte-secreted extracellular vesicles modify blood metabolome and endothelial function by an arginase-dependent mechanism

(2017) Felix Royo et al.   Scientific Reports

Liver immunology and its role in inflammation and homeostasis

(2016) Mark W Robinson et al.   Cellular & Molecular Immunology

Extracellular vesicles in liver pathobiology: Small particles with big impact

(2016) Petra Hirsova et al.   HEPATOLOGY

Emerging role of exosomes in liver physiology and pathology

(2016) Shuangpeng Cai et al.   HEPATOLOGY RESEARCH

Alcohol stimulates macrophage activation through caspase-dependent hepatocyte derived release of CD40L containing extracellular vesicles

(2016) Vikas K. Verma et al.   JOURNAL OF HEPATOLOGY

Exosomes in liver pathology

(2016) Keisaku Sato et al.   JOURNAL OF HEPATOLOGY

Myocyte-Derived Hsp90 Modulates Collagen Upregulation via Biphasic Activation of STAT-3 in Fibroblasts during Cardiac Hypertrophy

(2016) Ritwik Datta et al.   MOLECULAR AND CELLULAR BIOLOGY

Subtoxic Alterations in Hepatocyte-Derived Exosomes: An Early Step in Drug-Induced Liver Injury?

(2016) Natalie S. Holman et al.   TOXICOLOGICAL SCIENCES

Exosomes as Novel Regulators of Adult Neurogenic Niches

(2016) Luis Federico Bátiz et al.   Frontiers in Cellular Neuroscience

Inhibiting Extracellular Vesicle Release from Human Cardiosphere Derived Cells with Lentiviral Knockdown of nSMase2 Differentially Effects Proliferation and Apoptosis in Cardiomyocytes, Fibroblasts and Endothelial Cells In Vitro

(2016) Jennifer K. Lang et al.   PLoS One

Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs

(2015) Mian He et al.   CARCINOGENESIS

CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA

(2015) Alice Conigliaro et al.   Molecular Cancer

Extracellular Vesicles in Cancer: Exosomes, Microvesicles and the Emerging Role of Large Oncosomes

(2015) Valentina R. Minciacchi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Variance in the identification of microRNAs deregulated in Alzheimer's disease and possible role of lincRNAs in the pathology: The need of larger datasets

(2014) Pierre Lau et al.   AGEING RESEARCH REVIEWS

Cardiac fibroblast–derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy

(2014) Claudia Bang et al.   JOURNAL OF CLINICAL INVESTIGATION

Endothelial Microparticles Interact with and Support the Proliferation of T Cells

(2014) Julie Wheway et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-193b is a regulator of amyloid precursor protein in the blood and cerebrospinal fluid derived exosomal microRNA-193b is a biomarker of Alzheimer’s disease

(2014) CHEN-GENG LIU et al.   Molecular Medicine Reports

The emerging roles of microvesicles in liver diseases

(2014) Sara Lemoinne et al.   Nature Reviews Gastroenterology & Hepatology

Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity

(2013) Jianhua Li et al.   NATURE IMMUNOLOGY

Exosomes of BV-2 cells induced by alpha-synuclein: Important mediator of neurodegeneration in PD

(2013) Chongwang Chang et al.   NEUROSCIENCE LETTERS

Differential Stability of Cell-Free Circulating microRNAs: Implications for Their Utilization as Biomarkers

(2013) Verena Köberle et al.   PLoS One

Exosomes are endogenous nanoparticles that can deliver biological information between cells

(2012) Dongmei Sun et al.   ADVANCED DRUG DELIVERY REVIEWS

Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases

(2012) Shashi Bala et al.   HEPATOLOGY

The Exosome Secretory Pathway Transports Amyloid Precursor Protein Carboxyl-terminal Fragments from the Cell into the Brain Extracellular Space

(2012) Rocio Perez-Gonzalez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ESCRT Pathway

(2011) William M. Henne et al.   DEVELOPMENTAL CELL

Intercellular nanovesicle-mediated microRNA transfer: A mechanism of environmental modulation of hepatocellular cancer cell growth

(2011) Takayuki Kogure et al.   HEPATOLOGY

Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages

(2011) Cecilia Lässer et al.   Journal of Translational Medicine

Exosomes: Extracellular organelles important in intercellular communication

(2010) Suresh Mathivanan et al.   Journal of Proteomics

The Liver as a Lymphoid Organ

(2009) Ian Nicholas Crispe   Annual Review of Immunology

Exosomes: proteomic insights and diagnostic potential

(2009) Richard J Simpson et al.   Expert Review of Proteomics

Shedding microvesicles: artefacts no more

(2009) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Serum activity of alanine aminotransferase (ALT) as an indicator of health and disease

(2008) W. Ray Kim et al.   HEPATOLOGY