Priming of dendritic cells by DNA-containing extracellular vesicles from activated T cells through antigen-driven contacts

C. elegans neurons jettison protein aggregates and mitochondria under neurotoxic stress

(2017) Ilija Melentijevic et al.   NATURE

A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance

(2017) Babette C. Hammerling et al.   Nature Communications

Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells

(2017) Lan-Feng Dong et al.   eLife

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming

(2016) Michael D. Buck et al.   CELL

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

(2016) Mercedes Tkach et al.   CELL

Oxidized mitochondrial nucleoids released by neutrophils drive type I interferon production in human lupus

(2016) Simone Caielli et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflammasome-Derived Exosomes Activate NF-κB Signaling in Macrophages

(2016) Yuehui Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing

(2016) Ana Latorre-Pellicer et al.   NATURE

Transfer of mitochondria from astrocytes to neurons after stroke

(2016) Kazuhide Hayakawa et al.   NATURE

Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing

(2016) Qi Chen et al.   NATURE IMMUNOLOGY

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

(2016) Christian Lood et al.   NATURE MEDICINE

Trained immunity: A program of innate immune memory in health and disease

(2016) M. G. Netea et al.   SCIENCE

The Dendritic Cell Synapse: A Life Dedicated to T Cell Activation

(2016) Federica Benvenuti   Frontiers in Immunology

Mitochondrial Genome Acquisition Restores Respiratory Function and Tumorigenic Potential of Cancer Cells without Mitochondrial DNA

(2015) An S. Tan et al.   Cell Metabolism

Mitochondrial DNA stress primes the antiviral innate immune response

(2015) A. Phillip West et al.   NATURE

Double-stranded DNA in exosomes: a novel biomarker in cancer detection

(2014) Basant Kumar Thakur et al.   CELL RESEARCH

A new pathway for mitochondrial quality control: mitochondrial-derived vesicles

(2014) A. Sugiura et al.   EMBO JOURNAL

Identification of Double-stranded Genomic DNA Spanning All Chromosomes with MutatedKRASandp53DNA in the Serum Exosomes of Patients with Pancreatic Cancer

(2014) Christoph Kahlert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Revisiting Peptide Identification by High-Accuracy Mass Spectrometry: Problems Associated with the Use of Narrow Mass Precursor Windows

(2014) Elena Bonzon-Kulichenko et al.   JOURNAL OF PROTEOME RESEARCH

Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse

(2014) Kaushik Choudhuri et al.   NATURE

Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens

(2014) Nora Branzk et al.   NATURE IMMUNOLOGY

Resident memory CD8 T cells trigger protective innate and adaptive immune responses

(2014) J. M. Schenkel et al.   SCIENCE

Skin-resident memory CD8+ T cells trigger a state of tissue-wide pathogen alert

(2014) S. Ariotti et al.   SCIENCE

A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cells

(2014) N. Iijima et al.   SCIENCE

Sorting it out: Regulation of exosome loading

(2014) Carolina Villarroya-Beltri et al.   SEMINARS IN CANCER BIOLOGY

Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

(2013) Sara Cogliati et al.   CELL

The Intracellular Interactome of Tetraspanin-enriched Microdomains Reveals Their Function as Sorting Machineries toward Exosomes

(2013) Daniel Perez-Hernandez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Immune synapse: conductor of orchestrated organelle movement

(2013) Noa Beatriz Martín-Cófreces et al.   TRENDS IN CELL BIOLOGY

The Mitochondrial Nucleoid: Integrating Mitochondrial DNA into Cellular Homeostasis

(2013) R. Gilkerson et al.   Cold Spring Harbor Perspectives in Biology

Mitochondrial transfer from bone-marrow–derived stromal cells to pulmonary alveoli protects against acute lung injury

(2012) Mohammad Naimul Islam et al.   NATURE MEDICINE

Intercellular communication: diverse structures for exchange of genetic information

(2012) Maria Mittelbrunn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions

(2012) Esther N. M. Nolte-’t Hoen et al.   NUCLEIC ACIDS RESEARCH

T Cell Receptor Internalization from the Immunological Synapse Is Mediated by TC21 and RhoG GTPase-Dependent Phagocytosis

(2011) Nuria Martínez-Martín et al.   IMMUNITY

Mitochondrial Capture by a Transmissible Cancer

(2011) C. A. Rebbeck et al.   SCIENCE

Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

(2011) O. S. Qureshi et al.   SCIENCE

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

Programmed cell death of dendritic cells in immune regulation

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TheN-Ethyl-N-Nitrosourea-InducedGoldenticketMouse Mutant Reveals an Essential Function ofStingin theIn VivoInterferon Response toListeria monocytogenesand Cyclic Dinucleotides

(2010) John-Demian Sauer et al.   INFECTION AND IMMUNITY

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Rab7 Regulates Late Endocytic Trafficking Downstream of Multivesicular Body Biogenesis and Cargo Sequestration

(2009) Phillip A. Vanlandingham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

(2009) Hiroki Ishikawa et al.   NATURE

Immunological synapse formation inhibits, via NF-κB and FOXO1, the apoptosis of dendritic cells

(2009) Lorena Riol-Blanco et al.   NATURE IMMUNOLOGY

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Quantitative 3D Video Microscopy of HIV Transfer Across T Cell Virological Synapses

(2009) W. Hubner et al.   SCIENCE

Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission

(2008) Stefanie Sowinski et al.   NATURE CELL BIOLOGY

Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense

(2008) Shida Yousefi et al.   NATURE MEDICINE

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE