Liver immunology and its role in inflammation and homeostasis

Soluble Ligands and Their Receptors in Human Embryo Development and Implantation

(2015) George A. Thouas et al.   ENDOCRINE REVIEWS

Combination of Granulocyte Colony-Stimulating Factor and Erythropoietin Improves Outcomes of Patients With Decompensated Cirrhosis

(2015) Chandan Kumar Kedarisetty et al.   GASTROENTEROLOGY

Hepatic inflammation and fibrosis: Functional links and key pathways

(2015) Ekihiro Seki et al.   HEPATOLOGY

Kupffer cell-monocyte communication is essential for initiating murine liver progenitor cell-mediated liver regeneration

(2015) Caryn L. Elsegood et al.   HEPATOLOGY

Bidirectional transendothelial migration of monocytes across hepatic sinusoidal endothelium shapes monocyte differentiation and regulates the balance between immunity and tolerance in liver

(2015) Henning W. Zimmermann et al.   HEPATOLOGY

Liver inflammation abrogates immunological tolerance induced by Kupffer cells

(2015) Felix Heymann et al.   HEPATOLOGY

The yin and yang of evasion and immune activation in HCC

(2015) Oxana V. Makarova-Rusher et al.   JOURNAL OF HEPATOLOGY

Mechanisms of decompensation and organ failure in cirrhosis: From peripheral arterial vasodilation to systemic inflammation hypothesis

(2015) Mauro Bernardi et al.   JOURNAL OF HEPATOLOGY

Wound repair: role of immune–epithelial interactions

(2015) G Leoni et al.   Mucosal Immunology

Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells

(2015) Laura J Pallett et al.   NATURE MEDICINE

Hepatitis C virus and lipid droplets: finding a niche

(2015) Ana Filipe et al.   TRENDS IN MOLECULAR MEDICINE

Chemokine signaling in development and disease

(2014) J. Wang et al.   DEVELOPMENT

Immune tolerance in liver disease

(2014) Ian N. Crispe   HEPATOLOGY

Immune Responses to HCV and Other Hepatitis Viruses

(2014) Su-Hyung Park et al.   IMMUNITY

Hypoxia inducible factors in liver disease and hepatocellular carcinoma: Current understanding and future directions

(2014) Garrick K. Wilson et al.   JOURNAL OF HEPATOLOGY

Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of Treg cells and macrophages in adipose tissue

(2014) Lydia Lynch et al.   NATURE IMMUNOLOGY

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

(2014) S. Saeed et al.   SCIENCE

A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C

(2013) Bruno Sangro et al.   JOURNAL OF HEPATOLOGY

CD141+ myeloid dendritic cells are enriched in healthy human liver

(2013) Aoife Kelly et al.   JOURNAL OF HEPATOLOGY

Autoimmune liver disease, autoimmunity and liver transplantation

(2013) Marco Carbone et al.   JOURNAL OF HEPATOLOGY

Ex vivoanalysis of resident hepatic pro-inflammatory CD1d-reactive T cells and hepatocyte surface CD1d expression in hepatitis C

(2013) K. Yanagisawa et al.   JOURNAL OF VIRAL HEPATITIS

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Immune surveillance by the liver

(2013) Craig N Jenne et al.   NATURE IMMUNOLOGY

Characterizing the Lymphopoietic Kinetics and Features of Hematopoietic Progenitors Contained in the Adult Murine Liver In Vivo

(2013) Xiaojun Jiang et al.   PLoS One

Liver-Primed Memory T Cells Generated under Noninflammatory Conditions Provide Anti-infectious Immunity

(2013) Jan P. Böttcher et al.   Cell Reports

Sterile Inflammation in the Liver

(2012) Paul Kubes et al.   GASTROENTEROLOGY

Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice

(2012) Kouichi Miura et al.   HEPATOLOGY

NK cells from HCV-infected patients effectively induce apoptosis of activated primary human hepatic stellate cells in a TRAIL-, FasL- and NKG2D-dependent manner

(2012) Andreas Glässner et al.   LABORATORY INVESTIGATION

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis

(2012) P. Ramachandran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunosuppressive functions of hepatic myeloid-derived suppressor cells of normal mice and in a murine model of chronic hepatitis B virus

(2011) S. Chen et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Liver Fibrosis Protects Mice From Acute Hepatocellular Injury

(2011) Éric Bourbonnais et al.   GASTROENTEROLOGY

Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells

(2011) Timea Csak et al.   HEPATOLOGY

Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration

(2011) Yann Malato et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatic Stellate Cells Function as Regulatory Bystanders

(2011) S. Ichikawa et al.   JOURNAL OF IMMUNOLOGY

Hepatocyte metabolic signalling pathways and regulation of hepatitis B virus expression

(2011) Iddo Bar-Yishay et al.   LIVER INTERNATIONAL

Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells

(2010) M. Dusseaux et al.   BLOOD

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Direct, help-independent priming of CD8+ T cells by adeno-associated virus-transduced hepatocytes

(2010) Sherry A. Wuensch et al.   HEPATOLOGY

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function

(2010) Leif E. Sander et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Liver grafts contain a unique subset of natural killer cells that are transferred into the recipient after liver transplantation

(2010) Viviana Moroso et al.   LIVER TRANSPLANTATION

The Liver as a Lymphoid Organ

(2009) Ian Nicholas Crispe   Annual Review of Immunology

Novel mechanism of C-reactive protein for enhancing mouse liver innate immunity

(2009) Akihito Inatsu et al.   HEPATOLOGY

Hepatic recruitment of the inflammatory Gr1+monocyte subset upon liver injury promotes hepatic fibrosis

(2009) Karlin Raja Karlmark et al.   HEPATOLOGY

Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific

(2009) Jun Wu et al.   IMMUNOLOGY

Human Liver Dendritic Cells Promote T Cell Hyporesponsiveness

(2009) Z. M. Bamboat et al.   JOURNAL OF IMMUNOLOGY

Liver natural killer and natural killer T cells: immunobiology and emerging roles in liver diseases

(2009) B. Gao et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Microanatomy of the liver immune system

(2009) Eszter Nemeth et al.   Seminars in Immunopathology

Activation of innate immunity (NK/IFN-γ) in rat allogeneic liver transplantation: contribution to liver injury and suppression of hepatocyte proliferation

(2008) Kezhen Shen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Toll‐like receptors and adaptor molecules in liver disease: Update

(2008) Ekihiro Seki et al.   HEPATOLOGY

TLR-dependent cross talk between human Kupffer cells and NK cells

(2008) Zhengkun Tu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Poor allostimulatory function of liver plasmacytoid DC is associated with pro-apoptotic activity, dependent on regulatory T cells

(2008) Daisuke Tokita et al.   JOURNAL OF HEPATOLOGY