Extracellular vesicles from mice with alcoholic liver disease carry a distinct protein cargo and induce macrophage activation through heat shock protein 90

Pathophysiology and Management of Alcoholic Liver Disease: Update 2016

(2017) Felix Stickel et al.   Gut and Liver

Extracellular Vesicles: Unique Intercellular Delivery Vehicles

(2017) Sybren L.N. Maas et al.   TRENDS IN CELL BIOLOGY

Increased liver-specific proteins in circulating extracellular vesicles as potential biomarkers for drug- and alcohol-induced liver injury

(2017) Young-Eun Cho et al.   PLoS One

Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood

(2016) Akiko Eguchi et al.   HEPATOLOGY

Inhibition of spleen tyrosine kinase activation ameliorates inflammation, cell death, and steatosis in alcoholic liver disease

(2016) Terence N. Bukong et al.   HEPATOLOGY

Extracellular vesicles in liver pathobiology: Small particles with big impact

(2016) Petra Hirsova et al.   HEPATOLOGY

Alcohol stimulates macrophage activation through caspase-dependent hepatocyte derived release of CD40L containing extracellular vesicles

(2016) Vikas K. Verma et al.   JOURNAL OF HEPATOLOGY

ExoCarta: A Web-Based Compendium of Exosomal Cargo

(2016) Shivakumar Keerthikumar et al.   JOURNAL OF MOLECULAR BIOLOGY

Monocyte Heterogeneity: Consequences for Monocyte-Derived Immune Cells

(2016) Sara Sprangers et al.   Journal of Immunology Research

Critical Roles of Kupffer Cells in the Pathogenesis of Alcoholic Liver Disease: From Basic Science to Clinical Trials

(2016) Tao Zeng et al.   Frontiers in Immunology

Hepatocellular carcinoma is accelerated by NASH involving M2 macrophage polarization mediated by hif-1αinduced IL-10

(2016) Aditya Ambade et al.   OncoImmunology

Reprogramming macrophage orientation by microRNA 146b targeting transcription factor IRF5

(2016) Liang Peng et al.   EBioMedicine

Differential and transferable modulatory effects of mesenchymal stromal cell-derived extracellular vesicles on T, B and NK cell functions

(2016) Mariano Di Trapani et al.   Scientific Reports

Alcohol-Induced miR-27a Regulates Differentiation and M2 Macrophage Polarization of Normal Human Monocytes

(2015) Banishree Saha et al.   JOURNAL OF IMMUNOLOGY

Krüppel-like factor 4 is a transcriptional regulator of M1/M2 macrophage polarization in alcoholic liver disease

(2015) Banishree Saha et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Increased number of circulating exosomes and their microRNA cargos are potential novel biomarkers in alcoholic hepatitis

(2015) Fatemeh Momen-Heravi et al.   Journal of Translational Medicine

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

(2015) Bruno Costa-Silva et al.   NATURE CELL BIOLOGY

Biodistribution and function of extracellular miRNA-155 in mice

(2015) Shashi Bala et al.   Scientific Reports

Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS

(2015) Fatemeh Momen-Heravi et al.   Scientific Reports

Exosome Transfer from Stromal to Breast Cancer Cells Regulates Therapy Resistance Pathways

(2014) Mirjam C. Boelens et al.   CELL

Inhibition of heat shock protein 90 alleviates steatosis and macrophage activation in murine alcoholic liver injury

(2014) Aditya Ambade et al.   JOURNAL OF HEPATOLOGY

Chronic alcohol ingestion modulates hepatic macrophage populations and functions in mice

(2014) Meng Wang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Quantitative proteomic analysis of hepatocyte-secreted extracellular vesicles reveals candidate markers for liver toxicity

(2014) Eva Rodríguez-Suárez et al.   Journal of Proteomics

Proteomic Profiling of Exosomes Leads to the Identification of Novel Biomarkers for Prostate Cancer

(2014) Diederick Duijvesz et al.   PLoS One

Circulating Extracellular Vesicles with Specific Proteome and Liver MicroRNAs Are Potential Biomarkers for Liver Injury in Experimental Fatty Liver Disease

(2014) Davide Povero et al.   PLoS One

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

Exosomes in the pathogenesis, diagnostics and therapeutics of liver diseases

(2013) Anatoliy I. Masyuk et al.   JOURNAL OF HEPATOLOGY

MicroRNA-30a inhibits cell migration and invasion by downregulating vimentin expression and is a potential prognostic marker in breast cancer

(2012) Chun-Wen Cheng et al.   BREAST CANCER RESEARCH AND TREATMENT

IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice

(2012) Jan Petrasek et al.   JOURNAL OF CLINICAL INVESTIGATION

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT)

(2011) Zhen Wang et al.   PROTEOMICS

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

Alcohol exposure regulates heat shock transcription factor binding and heat shock proteins 70 and 90 in monocytes and macrophages: implication for TNF-α regulation

(2008) Pranoti Mandrekar et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes

(2008) Javier Conde-Vancells et al.   JOURNAL OF PROTEOME RESEARCH