Berberine ameliorates lipopolysaccharide-induced acute lung injury via the PERK-mediated Nrf2/HO-1 signaling axis

Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer’s disease

(2018) Ean-Jeong Seo et al.   PHARMACOLOGICAL RESEARCH

Methane ameliorates spinal cord ischemia-reperfusion injury in rats: Antioxidant, anti-inflammatory and anti-apoptotic activity mediated by Nrf2 activation

(2017) Liping Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

4-PBA inhibits LPS-induced inflammation through regulating ER stress and autophagy in acute lung injury models

(2017) Meichun Zeng et al.   TOXICOLOGY LETTERS

Acyloxyacyl hydrolase promotes the resolution of lipopolysaccharide-induced acute lung injury

(2017) Benkun Zou et al.   PLoS Pathogens

Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation

(2017) Hong Yao et al.   Frontiers in Pharmacology

FXYD5 Is an Essential Mediator of the Inflammatory Response during Lung Injury

(2017) Patricia L. Brazee et al.   Frontiers in Immunology

Xanthohumol ameliorates lipopolysaccharide (LPS)-induced acute lung injury via induction of AMPK/GSK3β-Nrf2 signal axis

(2017) Hongming Lv et al.   Redox Biology

Berberine protects rat heart from ischemia/reperfusion injury via activating JAK2/STAT3 signaling and attenuating endoplasmic reticulum stress

(2016) Guo-long Zhao et al.   ACTA PHARMACOLOGICA SINICA

Classically Activated Macrophages Protect against Lipopolysaccharide-induced Acute Lung Injury by Expressing Amphiregulin in Mice

(2016) Younian Xu et al.   ANESTHESIOLOGY

Activation of MTOR in pulmonary epithelium promotes LPS-induced acute lung injury

(2016) Yue Hu et al.   Autophagy

LFG-500, a newly synthesized flavonoid, attenuates lipopolysaccharide-induced acute lung injury and inflammation in mice

(2016) Chenglin Li et al.   BIOCHEMICAL PHARMACOLOGY

Thrombospondin 1 protects pancreatic β-cells from lipotoxicity via the PERK–NRF2 pathway

(2016) Daniel A Cunha et al.   CELL DEATH AND DIFFERENTIATION

Berberine: New Insights from Pharmacological Aspects to Clinical Evidences in the Management of Metabolic Disorders

(2016) Cristiana Caliceti et al.   CURRENT MEDICINAL CHEMISTRY

Lipoxin A4 attenuates LPS-induced mouse acute lung injury via Nrf2-mediated E-cadherin expression in airway epithelial cells

(2016) Xue Cheng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Alveolar Type II Epithelial Cells Contribute to the Anti-Influenza A Virus Response in the Lung by Integrating Pathogen- and Microenvironment-Derived Signals

(2016) S. Stegemann-Koniszewski et al.   mBio

Omentin protects against LPS-induced ARDS through suppressing pulmonary inflammation and promoting endothelial barrier via an Akt/eNOS-dependent mechanism

(2016) Di Qi et al.   Cell Death & Disease

Rhizoma Coptidis: A Potential Cardiovascular Protective Agent

(2016) Hui-Li Tan et al.   Frontiers in Pharmacology

The Role of Endoplasmic Reticulum Stress in Human Pathology

(2015) Scott A. Oakes et al.   Annual Review of Pathology-Mechanisms of Disease

Berberine, a plant alkaloid with lipid- and glucose-lowering properties: From in vitro evidence to clinical studies

(2015) Angela Pirillo et al.   ATHEROSCLEROSIS

Activated AMPK boosts the Nrf2/HO-1 signaling axis—A role for the unfolded protein response

(2015) Kristin Zimmermann et al.   FREE RADICAL BIOLOGY AND MEDICINE

Phosphoinositide 3-kinase-δ regulates fungus-induced allergic lung inflammation through endoplasmic reticulum stress

(2015) Kyung Sun Lee et al.   THORAX

Blockade of Interplay between IL-17A and Endoplasmic Reticulum Stress Attenuates LPS-Induced Lung Injury

(2015) So Ri Kim et al.   Theranostics

Acute Lung Injury Results from Innate Sensing of Viruses by an ER Stress Pathway

(2015) Eike R. Hrincius et al.   Cell Reports

Maresin 1 mitigates LPS-induced acute lung injury in mice

(2014) Jie Gong et al.   BRITISH JOURNAL OF PHARMACOLOGY

Baicalin Ameliorates H2O2 Induced Cytotoxicity in HK-2 Cells through the Inhibition of ER Stress and the Activation of Nrf2 Signaling

(2014) Miao Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

The Crosstalk Between Nrf2 and AMPK Signal Pathways Is Important for the Anti-Inflammatory Effect of Berberine in LPS-Stimulated Macrophages and Endotoxin-Shocked Mice

(2013) Chunfen Mo et al.   ANTIOXIDANTS & REDOX SIGNALING

Levo-tetrahydropalmatine decreases ethanol drinking and antagonizes dopamine D2 receptor-mediated signaling in the mouse dorsal striatum

(2013) Taehyun Kim et al.   BEHAVIOURAL BRAIN RESEARCH

TNF-α–mediated bronchial barrier disruption and regulation by src-family kinase activation

(2013) Michelle A. Hardyman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Alcoholic lung injury: Metabolic, biochemical and immunological aspects

(2013) Lata Kaphalia et al.   TOXICOLOGY LETTERS

Berberine attenuates bleomycin induced pulmonary toxicity and fibrosis via suppressing NF-κB dependant TGF-β activation: A biphasic experimental study

(2013) Palanivel Chitra et al.   TOXICOLOGY LETTERS

Inhibition of endoplasmic reticulum stress alleviates lipopolysaccharide-induced lung inflammation through modulation of NF-κB/HIF-1α signaling pathway

(2013) Hee Jung Kim et al.   Scientific Reports

The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation

(2012) Holly K. Bryan et al.   BIOCHEMICAL PHARMACOLOGY

Andrographolide protects against cigarette smoke-induced oxidative lung injury via augmentation of Nrf2 activity

(2012) SP Guan et al.   BRITISH JOURNAL OF PHARMACOLOGY

The acute respiratory distress syndrome

(2012) Michael A. Matthay et al.   JOURNAL OF CLINICAL INVESTIGATION

Agents that act luminally to treat diarrhoea and constipation

(2012) Stacy Menees et al.   Nature Reviews Gastroenterology & Hepatology

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An Official American Thoracic Society Workshop Report: Features and Measurements of Experimental Acute Lung Injury in Animals

(2011) Gustavo Matute-Bello et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Berberine hydrochloride: anticancer activity and nanoparticulate delivery system

(2011) Wen Tan et al.   International Journal of Nanomedicine

Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation

(2011) Brooks M. Hybertson et al.   MOLECULAR ASPECTS OF MEDICINE

NRF2 targeting: a promising therapeutic strategy in chronic obstructive pulmonary disease

(2011) A. Boutten et al.   TRENDS IN MOLECULAR MEDICINE

Berberine reduces endoplasmic reticulum stress and improves insulin signal transduction in Hep G2 cells

(2010) Zeng-si Wang et al.   ACTA PHARMACOLOGICA SINICA

Diabetes is an inflammatory disease: evidence from traditional Chinese medicines

(2010) W. Xie et al.   DIABETES OBESITY & METABOLISM

Oxidative stress targets in pulmonary emphysema: focus on the Nrf2 pathway

(2010) A Boutten et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

BiP Binding to the ER-Stress Sensor Ire1 Tunes the Homeostatic Behavior of the Unfolded Protein Response

(2010) David Pincus et al.   PLOS BIOLOGY