The ERK and JNK pathways in the regulation of metabolic reprogramming
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Title
The ERK and JNK pathways in the regulation of metabolic reprogramming
Authors
Keywords
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Journal
ONCOGENE
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2018-11-28
DOI
10.1038/s41388-018-0582-8
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Note: Only part of the references are listed.- The redox requirements of proliferating mammalian cells
- (2018) Aaron M. Hosios et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Macrophage plasticity, polarization, and function in health and disease
- (2018) Abbas Shapouri-Moghaddam et al. JOURNAL OF CELLULAR PHYSIOLOGY
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- (2018) Matthew Dankner et al. ONCOGENE
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- (2018) Raeeka Khamari et al. Cell Death & Disease
- The Role for Myc in Coordinating Glycolysis, Oxidative Phosphorylation, Glutaminolysis, and Fatty Acid Metabolism in Normal and Neoplastic Tissues
- (2018) Eric S. Goetzman et al. Frontiers in Endocrinology
- CAB39L elicited an anti-Warburg effect via a LKB1-AMPK-PGC1α axis to inhibit gastric tumorigenesis
- (2018) Weilin Li et al. ONCOGENE
- Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis
- (2017) Madhav Kishore et al. IMMUNITY
- JNK at the crossroad of obesity, insulin resistance, and cell stress response
- (2017) Giovanni Solinas et al. Molecular Metabolism
- Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition
- (2017) Keisha N. Hardeman et al. Scientific Reports
- EGFR Signaling Enhances Aerobic Glycolysis in Triple-Negative Breast Cancer Cells to Promote Tumor Growth and Immune Escape
- (2016) S.-O. Lim et al. CANCER RESEARCH
- The Emerging Hallmarks of Cancer Metabolism
- (2016) Natalya N. Pavlova et al. Cell Metabolism
- Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma
- (2016) Talya L. Dayton et al. GENES & DEVELOPMENT
- Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis
- (2016) Xinjian Li et al. MOLECULAR CELL
- Emerging concepts of T cell metabolism as a target of immunotherapy
- (2016) Chih-Hao Chang et al. NATURE IMMUNOLOGY
- Cancer metabolism: a therapeutic perspective
- (2016) Ubaldo E. Martinez-Outschoorn et al. Nature Reviews Clinical Oncology
- The Warburg Effect: How Does it Benefit Cancer Cells?
- (2016) Maria V. Liberti et al. TRENDS IN BIOCHEMICAL SCIENCES
- AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs
- (2016) D. Grahame Hardie et al. TRENDS IN CELL BIOLOGY
- HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity
- (2016) Hiroaki Semba et al. Nature Communications
- Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages
- (2016) Jan Van den Bossche et al. Cell Reports
- An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis
- (2015) Kıvanç Birsoy et al. CELL
- Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells
- (2015) Lucas B. Sullivan et al. CELL
- Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
- (2015) Ping-Chih Ho et al. CELL
- Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
- (2015) Eva M. Palsson-McDermott et al. Cell Metabolism
- NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus
- (2015) Carles Cantó et al. Cell Metabolism
- Molecular Pathways: Is AMPK a Friend or a Foe in Cancer?
- (2015) D. G. Hardie CLINICAL CANCER RESEARCH
- Negative regulation of the LKB1/AMPK pathway by ERK in human acute myeloid leukemia cells
- (2015) Ichiro Kawashima et al. EXPERIMENTAL HEMATOLOGY
- Immunometabolism governs dendritic cell and macrophage function
- (2015) Luke A.J. O’Neill et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Pyruvate Kinase Isoform Expression Alters Nucleotide Synthesis to Impact Cell Proliferation
- (2015) Sophia Y. Lunt et al. MOLECULAR CELL
- Pyruvate kinase: Function, regulation and role in cancer
- (2015) William J. Israelsen et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation
- (2015) Valeria Iansante et al. Nature Communications
- MYC, Metabolism, and Cancer
- (2015) Z. E. Stine et al. Cancer Discovery
- Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the V600EBRAF oncogene
- (2015) Arnaldur Hall et al. Oncotarget
- Cell-State-Specific Metabolic Dependency in Hematopoiesis and Leukemogenesis
- (2014) Ying-Hua Wang et al. CELL
- The PPARα-FGF21 Hormone Axis Contributes to Metabolic Regulation by the Hepatic JNK Signaling Pathway
- (2014) Santiago Vernia et al. Cell Metabolism
- Aerobic Glycolysis in the Human Brain Is Associated with Development and Neotenous Gene Expression
- (2014) Manu S. Goyal et al. Cell Metabolism
- c-Myc Programs Fatty Acid Metabolism and Dictates Acetyl-CoA Abundance and Fate
- (2014) Lia R. Edmunds et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Metabolism of stromal and immune cells in health and disease
- (2014) Bart Ghesquière et al. NATURE
- The clinical development of MEK inhibitors
- (2014) Yujie Zhao et al. Nature Reviews Clinical Oncology
- Combined BRAF and MEK Inhibition versus BRAF Inhibition Alone in Melanoma
- (2014) Georgina V. Long et al. NEW ENGLAND JOURNAL OF MEDICINE
- Chaetocin-induced ROS-mediated apoptosis involves ATM–YAP1 axis and JNK-dependent inhibition of glucose metabolism
- (2014) D Dixit et al. Cell Death & Disease
- Glutamine deprivation stimulates mTOR-JNK-dependent chemokine secretion
- (2014) Naval P. Shanware et al. Nature Communications
- Response of BRAF-Mutant Melanoma to BRAF Inhibition Is Mediated by a Network of Transcriptional Regulators of Glycolysis
- (2014) T. J. Parmenter et al. Cancer Discovery
- JNK signalling in cancer: in need of new, smarter therapeutic targets
- (2013) Concetta Bubici et al. BRITISH JOURNAL OF PHARMACOLOGY
- Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF
- (2013) Rizwan Haq et al. CANCER CELL
- MEK1/2 Inhibition Decreases Lactate in BRAF-Driven Human Cancer Cells
- (2013) Maria Falck Miniotis et al. CANCER RESEARCH
- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
- PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells
- (2013) William J. Israelsen et al. CELL
- A Role for Peroxisome Proliferator-Activated Receptor γ Coactivator-1 in the Control of Mitochondrial Dynamics During Postnatal Cardiac Growth
- (2013) Ola J. Martin et al. CIRCULATION RESEARCH
- AMPK-Dependent Degradation of TXNIP upon Energy Stress Leads to Enhanced Glucose Uptake via GLUT1
- (2013) Ning Wu et al. MOLECULAR CELL
- Metabolism of inflammation limited by AMPK and pseudo-starvation
- (2013) Luke A. J. O'Neill et al. NATURE
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
- (2013) G. M. Tannahill et al. NATURE
- Metabolic targets for cancer therapy
- (2013) Lorenzo Galluzzi et al. NATURE REVIEWS DRUG DISCOVERY
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- (2012) B. Everts et al. BLOOD
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- (2012) Haoqiang Ying et al. CELL
- Orchestration of Metabolism by Macrophages
- (2012) Subhra K. Biswas et al. Cell Metabolism
- AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo
- (2012) Brandon Faubert et al. Cell Metabolism
- HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition
- (2012) Wenyu Zhou et al. EMBO JOURNAL
- Macrophage polarization and plasticity in health and disease
- (2012) Subhra K. Biswas et al. IMMUNOLOGIC RESEARCH
- Metabolic differentiation in the embryonic retina
- (2012) Michalis Agathocleous et al. NATURE CELL BIOLOGY
- ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
- (2012) Weiwei Yang et al. NATURE CELL BIOLOGY
- Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
- (2012) Dimitrios Anastasiou et al. Nature Chemical Biology
- Metabolic checkpoints in activated T cells
- (2012) Ruoning Wang et al. NATURE IMMUNOLOGY
- Metabolic reprogramming of the tumor
- (2012) L M R Ferreira et al. ONCOGENE
- Poly(ADP-ribose) polymerase family member 14 (PARP14) is a novel effector of the JNK2-dependent pro-survival signal in multiple myeloma
- (2012) A Barbarulo et al. ONCOGENE
- M2 isoform of pyruvate kinase is dispensable for tumor maintenance and growth
- (2012) M. Cortes-Cros et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nuclear Reprogramming with c-Myc Potentiates Glycolytic Capacity of Derived Induced Pluripotent Stem Cells
- (2012) Clifford D. L. Folmes et al. Journal of Cardiovascular Translational Research
- Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
- (2011) Sophia Y. Lunt et al. Annual Review of Cell and Developmental Biology
- Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
- (2011) Eric V. Dang et al. CELL
- Metabolic Flux and the Regulation of Mammalian Cell Growth
- (2011) Jason W. Locasale et al. Cell Metabolism
- Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming
- (2011) Clifford D.L. Folmes et al. Cell Metabolism
- The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming
- (2011) Athanasia D Panopoulos et al. CELL RESEARCH
- The Permeability Transition Pore Controls Cardiac Mitochondrial Maturation and Myocyte Differentiation
- (2011) Jennifer R. Hom et al. DEVELOPMENTAL CELL
- Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
- (2011) A. R. Grassian et al. GENES & DEVELOPMENT
- JNK1 and JNK2 play redundant functions in Myc-induced B cell lymphoma formation
- (2011) Moorthy Anbalagan et al. INTERNATIONAL JOURNAL OF CANCER
- HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells
- (2011) Lewis Z. Shi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Relevance of the MEK/ERK Signaling Pathway in the Metabolism of Activated Macrophages: A Metabolomic Approach
- (2011) P. G. Traves et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
- (2011) R. D. Michalek et al. JOURNAL OF IMMUNOLOGY
- Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
- (2011) M. Cargnello et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- TLR signalling augments macrophage bactericidal activity through mitochondrial ROS
- (2011) A. Phillip West et al. NATURE
- Energy Metabolism in Human Pluripotent Stem Cells and Their Differentiated Counterparts
- (2011) Sandra Varum et al. PLoS One
- Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation
- (2010) C. M. Krawczyk et al. BLOOD
- The c-Jun NH2-Terminal Kinase 2 Plays a Dominant Role in Human Epidermal Neoplasia
- (2010) H. Ke et al. CANCER RESEARCH
- Mitochondrial Localization and Regulation of BRAFV600Ein Thyroid Cancer: A Clinically Used RAF Inhibitor Is Unable to Block the Mitochondrial Activities of BRAFV600E
- (2010) Min Hee Lee et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue
- (2010) Aliki Kosteli et al. JOURNAL OF CLINICAL INVESTIGATION
- Glycolytic network restructuring integral to the energetics of embryonic stem cell cardiac differentiation
- (2010) Susan Chung et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- ERK activation drives intestinal tumorigenesis in Apcmin/+ mice
- (2010) Sung Hee Lee et al. NATURE MEDICINE
- Role of JNK in a Trp53-Dependent Mouse Model of Breast Cancer
- (2010) Cristina Cellurale et al. PLoS One
- Induction of Glucose Metabolism in Stimulated T Lymphocytes Is Regulated by Mitogen-Activated Protein Kinase Signaling
- (2010) Aimee J. Marko et al. PLoS One
- The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes
- (2010) A. J. Levine et al. SCIENCE
- Detection of BRAF mutations in the tumour and serum of patients enrolled in the AZD6244 (ARRY-142886) advanced melanoma phase II study
- (2009) R E Board et al. BRITISH JOURNAL OF CANCER
- MYC-Induced Cancer Cell Energy Metabolism and Therapeutic Opportunities
- (2009) C. V. Dang et al. CLINICAL CANCER RESEARCH
- Tumor suppressors and cell metabolism: a recipe for cancer growth
- (2009) R. G. Jones et al. GENES & DEVELOPMENT
- Oncogenic B-RAF Negatively Regulates the Tumor Suppressor LKB1 to Promote Melanoma Cell Proliferation
- (2009) Bin Zheng et al. MOLECULAR CELL
- HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
- (2009) Charles J. David et al. NATURE
- Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells
- (2009) J. Yun et al. SCIENCE
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth
- (2009) T. Hitosugi et al. Science Signaling
- Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer
- (2008) E D Michelakis et al. BRITISH JOURNAL OF CANCER
- Tumor Cell Metabolism: Cancer's Achilles' Heel
- (2008) Guido Kroemer et al. CANCER CELL
- Cancer Cell Metabolism: Warburg and Beyond
- (2008) Peggy P. Hsu et al. CELL
- Phosphorylation of Bad at Thr-201 by JNK1 Promotes Glycolysis through Activation of Phosphofructokinase-1
- (2008) Hongbin Deng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation
- (2008) Lijian Hui et al. JOURNAL OF CLINICAL INVESTIGATION
- Pyruvate kinase M2 is a phosphotyrosine-binding protein
- (2008) Heather R. Christofk et al. NATURE
- The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
- (2008) Heather R. Christofk et al. NATURE
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