Cell migration: implications for repair and regeneration in joint disease

Impacts of maturation on the micromechanics of the meniscus extracellular matrix

(2018) Qing Li et al.   JOURNAL OF BIOMECHANICS

Enucleated cells reveal differential roles of the nucleus in cell migration, polarity, and mechanotransduction

(2018) David M. Graham et al.   JOURNAL OF CELL BIOLOGY

Chondrocyte and mesenchymal stem cell derived engineered cartilage exhibits differential sensitivity to pro-inflammatory cytokines

(2018) Bhavana Mohanraj et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Osteoarthritis as a disease of the cartilage pericellular matrix

(2018) Farshid Guilak et al.   MATRIX BIOLOGY

Quantitative evaluation of knee cartilage and meniscus destruction in patients with rheumatoid arthritis using T1ρ and T2 mapping

(2017) Xiang Hong Meng et al.   EUROPEAN JOURNAL OF RADIOLOGY

Disease-Specific Effects of Matrix and Growth Factors on Adhesion and Migration of Rheumatoid Synovial Fibroblasts

(2017) Stephanie Lefèvre et al.   JOURNAL OF IMMUNOLOGY

An antigen-encapsulating nanoparticle platform for TH1/17 immune tolerance therapy

(2017) Derrick P. McCarthy et al.   Nanomedicine-Nanotechnology Biology and Medicine

Mechanical confinement regulates cartilage matrix formation by chondrocytes

(2017) Hong-pyo Lee et al.   NATURE MATERIALS

3D Bioprinting for Cartilage and Osteochondral Tissue Engineering

(2017) Andrew C. Daly et al.   Advanced Healthcare Materials

CRISPR/Cas9 Editing of Murine Induced Pluripotent Stem Cells for Engineering Inflammation-Resistant Tissues

(2017) Jonathan M. Brunger et al.   Arthritis & Rheumatology

Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs

(2017) Jonathan M. Brunger et al.   Stem Cell Reports

Nuclear envelope rupture and repair during cancer cell migration

(2016) C. M. Denais et al.   SCIENCE

The Host Immune Response to Tissue-Engineered Organs: Current Problems and Future Directions

(2016) Katherine Wiles et al.   TISSUE ENGINEERING PART B-REVIEWS

Evolving insights in cell–matrix interactions: Elucidating how non-soluble properties of the extracellular niche direct stem cell fate

(2015) Nick J. Walters et al.   Acta Biomaterialia

Aligned multilayered electrospun scaffolds for rotator cuff tendon tissue engineering

(2015) Steven B. Orr et al.   Acta Biomaterialia

A hydrogel bioink toolkit for mimicking native tissue biochemical and mechanical properties in bioprinted tissue constructs

(2015) Aleksander Skardal et al.   Acta Biomaterialia

Comparative immunohistochemical evaluation of the zonal distribution of extracellular matrix and inflammation markers in human meniscus in osteoarthritis and rheumatoid arthritis

(2015) Inga Katharina Fuhrmann et al.   ACTA HISTOCHEMICA

Nanofibrous Hydrogels with Spatially Patterned Biochemical Signals to Control Cell Behavior

(2015) Ryan J. Wade et al.   ADVANCED MATERIALS

Meniscal degeneration in human knee osteoarthritis: in situ hybridization and immunohistochemistry study

(2015) Mariano López-Franco et al.   ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY

Repair of dense connective tissues via biomaterial-mediated matrix reprogramming of the wound interface

(2015) Feini Qu et al.   BIOMATERIALS

Controlled dual delivery of fibroblast growth factor-2 and Interleukin-10 by heparin-based coacervate synergistically enhances ischemic heart repair

(2015) William C.W. Chen et al.   BIOMATERIALS

Sequential delivery of immunomodulatory cytokines to facilitate the M1-to-M2 transition of macrophages and enhance vascularization of bone scaffolds

(2015) Kara L. Spiller et al.   BIOMATERIALS

Migration in Confined 3D Environments Is Determined by a Combination of Adhesiveness, Nuclear Volume, Contractility, and Cell Stiffness

(2015) Lena A. Lautscham et al.   BIOPHYSICAL JOURNAL

Cortical Contractility Triggers a Stochastic Switch to Fast Amoeboid Cell Motility

(2015) Verena Ruprecht et al.   CELL

Confinement and Low Adhesion Induce Fast Amoeboid Migration of Slow Mesenchymal Cells

(2015) Yan-Jun Liu et al.   CELL

Inflammatory Cell Migration in Rheumatoid Arthritis: A Comprehensive Review

(2015) Erin Nevius et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

“Chemokine receptors as therapeutic targets: Why aren’t there more drugs?”

(2015) Roberto Solari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Biomaterial based modulation of macrophage polarization: a review and suggested design principles

(2015) Rukmani Sridharan et al.   Materials Today

The extracellular matrix and transforming growth factor-β1: Tale of a strained relationship

(2015) Boris Hinz   MATRIX BIOLOGY

Knockdown of ADAM10 inhibits migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis

(2015) DAN LI et al.   Molecular Medicine Reports

Measuring dynamic cell–material interactions and remodeling during 3D human mesenchymal stem cell migration in hydrogels

(2015) Kelly M. Schultz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substrate stress relaxation regulates cell spreading

(2015) Ovijit Chaudhuri et al.   Nature Communications

Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions

(2015) Stephanie I. Fraley et al.   Scientific Reports

T cell migration in rheumatoid arthritis

(2015) Mario Mellado   Frontiers in Immunology

Tendon and ligament regeneration and repair: Clinical relevance and developmental paradigm

(2015) Guang Yang et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease

(2014) Mark D. Turner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Micro-scale and meso-scale architectural cues cooperate and compete to direct aligned tissue formation

(2014) Christopher L. Gilchrist et al.   BIOMATERIALS

Tissue-engineered cartilage with inducible and tunable immunomodulatory properties

(2014) Katherine A. Glass et al.   BIOMATERIALS

3D Collagen Alignment Limits Protrusions to Enhance Breast Cancer Cell Persistence

(2014) Kristin M. Riching et al.   BIOPHYSICAL JOURNAL

Water Permeation Drives Tumor Cell Migration in Confined Microenvironments

(2014) Kimberly M. Stroka et al.   CELL

Cellular and molecular maturation in fetal and adult ovine calcaneal tendons

(2014) Valentina Russo et al.   JOURNAL OF ANATOMY

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

(2014) Takamasa Harada et al.   JOURNAL OF CELL BIOLOGY

Meniscus maturation in the swine model: changes occurring along with anterior to posterior and medial to lateral aspect during growth

(2014) Alessia Di Giancamillo et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Integrins and chondrocyte–matrix interactions in articular cartilage

(2014) Richard F. Loeser   MATRIX BIOLOGY

Extracellular matrix assembly: a multiscale deconstruction

(2014) Janna K. Mouw et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The role of small leucine-rich proteoglycans in osteoarthritis pathogenesis

(2014) G.-X. Ni et al.   OSTEOARTHRITIS AND CARTILAGE

Endogenous IL-22 Plays a Dual Role in Arthritis: Regulation of Established Arthritis via IFN-γ Responses

(2014) Shivali Justa et al.   PLoS One

Differences between the Cell Populations from the Peritenon and the Tendon Core with Regard to Their Potential Implication in Tendon Repair

(2014) Jennifer A. Cadby et al.   PLoS One

Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage

(2014) Jonathan M. Brunger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of compartmentalized pressure by a nuclear piston governs cell motility in a 3D matrix

(2014) R. J. Petrie et al.   SCIENCE

Intra-Articular Injection of Human Meniscus Stem/Progenitor Cells Promotes Meniscus Regeneration and Ameliorates Osteoarthritis Through Stromal Cell-Derived Factor-1/CXCR4-Mediated Homing

(2014) Weiliang Shen et al.   Stem Cells Translational Medicine

A peptide functionalized poly(ethylene glycol) (PEG) hydrogel for investigating the influence of biochemical and biophysical matrix properties on tumor cell migration

(2014) Samir P. Singh et al.   Biomaterials Science

Synovial stem cells and their responses to the porosity of microfibrous scaffold

(2013) Benjamin Li-Ping Lee et al.   Acta Biomaterialia

Fibrous hyaluronic acid hydrogels that direct MSC chondrogenesis through mechanical and adhesive cues

(2013) Iris L. Kim et al.   BIOMATERIALS

Tunable T cell immunity towards a protein antigen using polymersomes vs. solid-core nanoparticles

(2013) Armando Stano et al.   BIOMATERIALS

Multifunctional polymer scaffolds with adjustable pore size and chemoattractant gradients for studying cell matrix invasion

(2013) Alexandra M. Greiner et al.   BIOMATERIALS

Lentivirus delivery of IL-10 to promote and sustain macrophage polarization towards an anti-inflammatory phenotype

(2013) R.M. Boehler et al.   BIOTECHNOLOGY AND BIOENGINEERING

Hutchinson–Gilford progeria syndrome alters nuclear shape and reduces cell motility in three dimensional model substrates

(2013) Elizabeth A. Booth-Gauthier et al.   Integrative Biology

Nuclear Envelope Composition Determines the Ability of Neutrophil-type Cells to Passage through Micron-scale Constrictions

(2013) Amy C. Rowat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

(2013) Katarina Wolf et al.   JOURNAL OF CELL BIOLOGY

At the leading edge of three-dimensional cell migration

(2013) R. J. Petrie et al.   JOURNAL OF CELL SCIENCE

Novel 3D Electrospun Scaffolds with Fibers Oriented Randomly and Evenly in Three Dimensions to Closely Mimic the Unique Architectures of Extracellular Matrices in Soft Tissues: Fabrication and Mechanism Study

(2013) Shaobo Cai et al.   LANGMUIR

Characterization of mechanical and biochemical properties of developing embryonic tendon

(2013) J. E. Marturano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

A review of trends and limitations in hydrogel-rapid prototyping for tissue engineering

(2012) Thomas Billiet et al.   BIOMATERIALS

Integrating focal adhesion dynamics, cytoskeleton remodeling, and actin motor activity for predicting cell migration on 3D curved surfaces of the extracellular matrix

(2012) Min-Cheol Kim et al.   Integrative Biology

Matrix nanotopography as a regulator of cell function

(2012) Deok-Ho Kim et al.   JOURNAL OF CELL BIOLOGY

Deconstructing the third dimension – how 3D culture microenvironments alter cellular cues

(2012) Brendon M. Baker et al.   JOURNAL OF CELL SCIENCE

Fabrication of a three-dimensional nanofibrous scaffold with lattice pores using direct-write electrospinning

(2012) Jongwan Lee et al.   MATERIALS LETTERS

Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues

(2012) Jordan S. Miller et al.   NATURE MATERIALS

Viscoelastic Properties of Differentiating Blood Cells Are Fate- and Function-Dependent

(2012) Andrew E. Ekpenyong et al.   PLoS One

Independent regulation of tumor cell migration by matrix stiffness and confinement

(2012) A. Pathak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sacrificial nanofibrous composites provide instruction without impediment and enable functional tissue formation

(2012) B. M. Baker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineering Approaches to Immunotherapy

(2012) M. A. Swartz et al.   Science Translational Medicine

Genipin-Crosslinked Cartilage-Derived Matrix as a Scaffold for Human Adipose-Derived Stem Cell Chondrogenesis

(2012) Nai-Chen Cheng et al.   TISSUE ENGINEERING PART A

Porosity and Cell Preseeding Influence Electrospun Scaffold Maturation and Meniscus Integration In Vitro

(2012) Lara C. Ionescu et al.   TISSUE ENGINEERING PART A

Gradient biomaterials and their influences on cell migration

(2012) J. Wu et al.   Interface Focus

Gradients with Depth in Electrospun Fibrous Scaffolds for Directed Cell Behavior

(2011) Harini G. Sundararaghavan et al.   BIOMACROMOLECULES

The effect of anisotropic collagen-GAG scaffolds and growth factor supplementation on tendon cell recruitment, alignment, and metabolic activity

(2011) Steven R. Caliari et al.   BIOMATERIALS

Local suppression of pro-inflammatory cytokines and the effects in BMP-2-induced bone regeneration

(2011) Juthamas Ratanavaraporn et al.   BIOMATERIALS

Increasing the pore sizes of bone-mimetic electrospun scaffolds comprised of polycaprolactone, collagen I and hydroxyapatite to enhance cell infiltration

(2011) Matthew C. Phipps et al.   BIOMATERIALS

Elucidating the Role of Matrix Stiffness in 3D Cell Migration and Remodeling

(2011) M. Ehrbar et al.   BIOPHYSICAL JOURNAL

Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness

(2011) Amit Pathak et al.   Integrative Biology

Targeting chemokine receptors in chronic inflammatory diseases: An extensive review

(2011) Pim J. Koelink et al.   PHARMACOLOGY & THERAPEUTICS

Nanoparticle conjugation of antigen enhances cytotoxic T-cell responses in pulmonary vaccination

(2011) C. Nembrini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrins and their ligands in rheumatoid arthritis

(2011) Torsten Lowin et al.   ARTHRITIS RESEARCH & THERAPY

Bioactive hydrogels made from step-growth derived PEG–peptide macromers

(2010) Jordan S. Miller et al.   BIOMATERIALS

The effect of matrix characteristics on fibroblast proliferation in 3D gels

(2010) Katrin Bott et al.   BIOMATERIALS

Marrow-Derived stem cell motility in 3D synthetic scaffold is governed by geometry along with adhesivity and stiffness

(2010) Shelly R. Peyton et al.   BIOTECHNOLOGY AND BIOENGINEERING

Nuclear mechanics during cell migration

(2010) Peter Friedl et al.   CURRENT OPINION IN CELL BIOLOGY

Engineering hydrogels as extracellular matrix mimics

(2010) Hikmet Geckil et al.   Nanomedicine

Maturation State-Dependent Alterations in Meniscus Integration: Implications for Scaffold Design and Tissue Engineering

(2010) Lara C. Ionescu et al.   TISSUE ENGINEERING PART A

Proteolytic interstitial cell migration: a five-step process

(2009) Peter Friedl et al.   CANCER AND METASTASIS REVIEWS

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

Random versus directionally persistent cell migration

(2009) Ryan J. Petrie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Engineering on the Straight and Narrow: The Mechanics of Nanofibrous Assemblies for Fiber-Reinforced Tissue Regeneration

(2009) Robert L. Mauck et al.   TISSUE ENGINEERING PART B-REVIEWS

The matricellular functions of small leucine-rich proteoglycans (SLRPs)

(2009) Rosetta Merline et al.   Journal of Cell Communication and Signaling

Clinical implications of rotator cuff degeneration in the rheumatic shoulder

(2008) Michiel A. J. Van de Sande et al.   ARTHRITIS AND RHEUMATISM

The potential to improve cell infiltration in composite fiber-aligned electrospun scaffolds by the selective removal of sacrificial fibers

(2008) Brendon M. Baker et al.   BIOMATERIALS

The enhancement of chondrogenic differentiation of human mesenchymal stem cells by enzymatically regulated RGD functionalities

(2008) Chelsea N. Salinas et al.   BIOMATERIALS

Contact Guidance Mediated Three-Dimensional Cell Migration is Regulated by Rho/ROCK-Dependent Matrix Reorganization

(2008) Paolo P. Provenzano et al.   BIOPHYSICAL JOURNAL

Cell biology of embryonic migration

(2008) Satoshi Kurosaka et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients

(2008) Takuji Iwamoto et al.   FEBS Journal

Functional expression of the chemokine receptor CCR7 on fibroblast-like synoviocytes

(2008) H. Brühl et al.   RHEUMATOLOGY