Chondrocyte and mesenchymal stem cell derived engineered cartilage exhibits differential sensitivity to pro-inflammatory cytokines

Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs

(2017) Jonathan M. Brunger et al.   Stem Cell Reports

Functional consequences of glucose and oxygen deprivation on engineered mesenchymal stem cell-based cartilage constructs

(2015) M.J. Farrell et al.   OSTEOARTHRITIS AND CARTILAGE

Fibrous Scaffolds with Varied Fiber Chemistry and Growth Factor Delivery Promote Repair in a Porcine Cartilage Defect Model

(2015) Iris L. Kim et al.   TISSUE ENGINEERING PART A

Effects of Mesenchymal Stem Cell and Growth Factor Delivery on Cartilage Repair in a Mini-Pig Model

(2015) Matthew B. Fisher et al.   Cartilage

Use of Cartilage Derived From Murine Induced Pluripotent Stem Cells for Osteoarthritis Drug Screening

(2014) Vincent P. Willard et al.   Arthritis & Rheumatology

The influence of scaffold material on chondrocytes under inflammatory conditions

(2013) Heenam Kwon et al.   Acta Biomaterialia

Time-dependent functional maturation of scaffold-free cartilage tissue analogs

(2013) Bhavana Mohanraj et al.   JOURNAL OF BIOMECHANICS

A high throughput mechanical screening device for cartilage tissue engineering

(2013) Bhavana Mohanraj et al.   JOURNAL OF BIOMECHANICS

Synovial fluid concentrations and relative potency of interleukin-1 alpha and beta in cartilage and meniscus degradation

(2013) Amy L. McNulty et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Post-traumatic osteoarthritis: from mouse models to clinical trials

(2013) Christopher B. Little et al.   Nature Reviews Rheumatology

Hydrogels that mimic developmentally relevant matrix and N-cadherin interactions enhance MSC chondrogenesis

(2013) L. Bian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Cartilage Repair with a Photoreactive Adhesive-Hydrogel Composite

(2013) B. Sharma et al.   Science Translational Medicine

High mesenchymal stem cell seeding densities in hyaluronic acid hydrogels produce engineered cartilage with native tissue properties

(2012) Isaac E. Erickson et al.   Acta Biomaterialia

The inhibition by interleukin 1 of MSC chondrogenesis and the development of biomechanical properties in biomimetic 3D woven PCL scaffolds

(2012) Paul H. Ousema et al.   BIOMATERIALS

Transient exposure to TGF-3 improves the functional chondrogenesis of MSC-laden hyaluronic acid hydrogels

(2012) Minwook Kim et al.   Journal of the Mechanical Behavior of Biomedical Materials

A 3D cartilage – Inflammatory cell culture system for the modeling of human osteoarthritis

(2011) Lin Sun et al.   BIOMATERIALS

Engineered Cartilage Maturation Regulates Cytokine Production and Interleukin-1β Response

(2011) Silvia Francioli et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

The restoration of full-thickness cartilage defects with BMSCs and TGF-beta 1 loaded PLGA/fibrin gel constructs

(2010) Wei Wang et al.   BIOMATERIALS

Evaluation of the Complex Transcriptional Topography of Mesenchymal Stem Cell Chondrogenesis for Cartilage Tissue Engineering

(2010) Alice H. Huang et al.   TISSUE ENGINEERING PART A

New concepts on the immune modulation mediated by mesenchymal stem cells

(2010) Bruce A Bunnell et al.   Stem Cell Research & Therapy

Interleukin-1β and tumor necrosis factor α inhibit chondrogenesis by human mesenchymal stem cells through NF-κB-dependent pathways

(2009) N. Wehling et al.   ARTHRITIS AND RHEUMATISM

TNFα promotes osteogenic differentiation of human mesenchymal stem cells by triggering the NF-κB signaling pathway

(2009) Katrin Hess et al.   BONE

Mechanisms involved in the therapeutic properties of mesenchymal stem cells

(2009) Lindolfo da Silva Meirelles et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Novel selective MMP-13 inhibitors reduce collagen degradation in bovine articular and human osteoarthritis cartilage explants

(2009) Dorothea Piecha et al.   INFLAMMATION RESEARCH

Mechanics and mechanobiology of mesenchymal stem cell-based engineered cartilage

(2009) Alice H. Huang et al.   JOURNAL OF BIOMECHANICS

Composition-function relationships during IL-1-induced cartilage degradation and recovery

(2009) A.W. Palmer et al.   OSTEOARTHRITIS AND CARTILAGE

Mechanical load inhibits IL-1 induced matrix degradation in articular cartilage

(2009) P.A. Torzilli et al.   OSTEOARTHRITIS AND CARTILAGE

Transient Exposure to Transforming Growth Factor Beta 3 Improves the Mechanical Properties of Mesenchymal Stem Cell–Laden Cartilage Constructs in a Density-Dependent Manner

(2009) Alice H. Huang et al.   TISSUE ENGINEERING PART A

Differential Maturation and Structure–Function Relationships in Mesenchymal Stem Cell- and Chondrocyte-Seeded Hydrogels

(2009) Isaac E. Erickson et al.   TISSUE ENGINEERING PART A

ERK1/2 Activation Induced by Inflammatory Cytokines Compromises Effective Host Tissue Integration of Engineered Cartilage

(2009) Farida Djouad et al.   TISSUE ENGINEERING PART A

Functional Properties of Cell-Seeded Three-Dimensionally Woven Poly(ε-Caprolactone) Scaffolds for Cartilage Tissue Engineering

(2009) Franklin T. Moutos et al.   TISSUE ENGINEERING PART A

Cartilage Mechanical Response under Dynamic Compression at Physiological Stress Levels Following Collagenase Digestion

(2008) Seonghun Park et al.   ANNALS OF BIOMEDICAL ENGINEERING

Differences in Interleukin-1 Response Between Engineered and Native Cartilage

(2008) Eric G. Lima et al.   TISSUE ENGINEERING PART A