Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness

Pore size variable type I collagen gels and their interaction with glioma cells

(2010) Ya-li Yang et al.   BIOMATERIALS

Directed 3D cell alignment and elongation in microengineered hydrogels

(2010) Hug Aubin et al.   BIOMATERIALS

Dense type I collagen matrices that support cellular remodeling and microfabrication for studies of tumor angiogenesis and vasculogenesis in vitro

(2010) Valerie L. Cross et al.   BIOMATERIALS

Mechanical Force Affects Expression of an In Vitro Metastasis-Like Phenotype in HCT-8 Cells

(2010) Xin Tang et al.   BIOPHYSICAL JOURNAL

Pericellular Conditions Regulate Extent of Cell-Mediated Compaction of Collagen Gels

(2010) Mark D. Stevenson et al.   BIOPHYSICAL JOURNAL

Stretchy Proteins on Stretchy Substrates: The Important Elements of Integrin-Mediated Rigidity Sensing

(2010) Simon W. Moore et al.   DEVELOPMENTAL CELL

Extracellular matrix rigidity modulates neuroblastoma cell differentiation and N-myc expression

(2010) Wilbur A Lam et al.   Molecular Cancer

A distinctive role for focal adhesion proteins in three-dimensional cell motility

(2010) Stephanie I. Fraley et al.   NATURE CELL BIOLOGY

Measurement of mechanical tractions exerted by cells in three-dimensional matrices

(2010) Wesley R Legant et al.   NATURE METHODS

A mechanical model of actin stress fiber formation and substrate elasticity sensing in adherent cells

(2010) Sam Walcott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proangiogenic scaffolds as functional templates for cardiac tissue engineering

(2010) L. R. Madden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Comparisons of the Morphology, Migration, Cell Adhesions, and Actin Cytoskeleton of Fibroblasts in Four Different Three-Dimensional Extracellular Matrices

(2010) Kirsi M. Hakkinen et al.   TISSUE ENGINEERING PART A

Multiscale three-dimensional scaffolds for soft tissue engineering via multimodal electrospinning

(2009) Sherif Soliman et al.   Acta Biomaterialia

Particle-Tracking Microrheology of Living Cells: Principles and Applications

(2009) Denis Wirtz   Annual Review of Biophysics

Partially nanofibrous architecture of 3D tissue engineering scaffolds

(2009) Guobao Wei et al.   BIOMATERIALS

Probing cellular mechanobiology in three-dimensional culture with collagen–agarose matrices

(2009) Theresa A. Ulrich et al.   BIOMATERIALS

The regulation of tendon stem cell differentiation by the alignment of nanofibers

(2009) Zi Yin et al.   BIOMATERIALS

Rheology and Confocal Reflectance Microscopy as Probes of Mechanical Properties and Structure during Collagen and Collagen/Hyaluronan Self-Assembly

(2009) Ya-li Yang et al.   BIOPHYSICAL JOURNAL

Proteolytic interstitial cell migration: a five-step process

(2009) Peter Friedl et al.   CANCER AND METASTASIS REVIEWS

The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells

(2009) T. A. Ulrich et al.   CANCER RESEARCH

Live Cells Exert 3-Dimensional Traction Forces on Their Substrata

(2009) Sung Sik Hur et al.   Cellular and Molecular Bioengineering

Mechanical modes of ‘amoeboid’ cell migration

(2009) Tim Lämmermann et al.   CURRENT OPINION IN CELL BIOLOGY

Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited

(2009) Farideh Sabeh et al.   JOURNAL OF CELL BIOLOGY

One-dimensional topography underlies three-dimensional fibrillar cell migration

(2009) Andrew D. Doyle et al.   JOURNAL OF CELL BIOLOGY

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

Matrix Architecture Dictates Three-Dimensional Migration Modes of Human Macrophages: Differential Involvement of Proteases and Podosome-Like Structures

(2009) E. Van Goethem et al.   JOURNAL OF IMMUNOLOGY

Random versus directionally persistent cell migration

(2009) Ryan J. Petrie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates

(2009) D Yamazaki et al.   ONCOGENE

Non-Linear Elasticity of Extracellular Matrices Enables Contractile Cells to Communicate Local Position and Orientation

(2009) Jessamine P. Winer et al.   PLoS One

Quantifying cellular traction forces in three dimensions

(2009) Stacey A. Maskarinec et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microfabricated tissue gauges to measure and manipulate forces from 3D microtissues

(2009) W. R. Legant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cortical Factor Feedback Model for Cellular Locomotion and Cytofission

(2009) Shin I. Nishimura et al.   PLoS Computational Biology

Microarchitecture of Three-Dimensional Scaffolds Influences Cell Migration Behavior via Junction Interactions

(2008) Brendan A.C. Harley et al.   BIOPHYSICAL JOURNAL

Mapping Local Matrix Remodeling Induced by a Migrating Tumor Cell Using Three-Dimensional Multiple-Particle Tracking

(2008) Ryan J. Bloom et al.   BIOPHYSICAL JOURNAL

Substrate Modulus Directs Neural Stem Cell Behavior

(2008) Krishanu Saha et al.   BIOPHYSICAL JOURNAL

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

Extracellular Matrix Rigidity Promotes Invadopodia Activity

(2008) Nelson R. Alexander et al.   CURRENT BIOLOGY

Self-Organized Podosomes Are Dynamic Mechanosensors

(2008) Olivier Collin et al.   CURRENT BIOLOGY

Modulus-dependent macrophage adhesion and behavior

(2008) E. F. Irwin et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

The Role of Myosin II in Glioma Invasion of the Brain

(2008) Christopher Beadle et al.   MOLECULAR BIOLOGY OF THE CELL

Rapid leukocyte migration by integrin-independent flowing and squeezing

(2008) Tim Lämmermann et al.   NATURE

Traction Dynamics of Filopodia on Compliant Substrates

(2008) C. E. Chan et al.   SCIENCE

High Resolution Traction Force Microscopy Based on Experimental and Computational Advances

(2007) Benedikt Sabass et al.   BIOPHYSICAL JOURNAL

The simulation of stress fibre and focal adhesion development in cells on patterned substrates

(2007) A. Pathak et al.   Journal of the Royal Society Interface