A peptide functionalized poly(ethylene glycol) (PEG) hydrogel for investigating the influence of biochemical and biophysical matrix properties on tumor cell migration

Biomaterial arrays with defined adhesion ligand densities and matrix stiffness identify distinct phenotypes for tumorigenic and non-tumorigenic human mesenchymal cell types

(2014) Tyler D. Hansen et al.   Biomaterials Science

Cell Durotaxis on Polyelectrolyte Multilayers with Photogenerated Gradients of Modulus

(2013) Jessica S. Martinez et al.   BIOMACROMOLECULES

The influence of matrix properties on growth and morphogenesis of human pancreatic ductal epithelial cells in 3D

(2013) Asad Raza et al.   BIOMATERIALS

Differential effects of cell adhesion, modulus and VEGFR-2 inhibition on capillary network formation in synthetic hydrogel arrays

(2013) Eric H. Nguyen et al.   BIOMATERIALS

Three-dimensional photolithographic micropatterning: a novel tool to probe the complexities of cell migration

(2013) Joseph C. Hoffmann et al.   Integrative Biology

A Quantitative Comparison of Human HT-1080 Fibrosarcoma Cells and Primary Human Dermal Fibroblasts Identifies a 3D Migration Mechanism with Properties Unique to the Transformed Phenotype

(2013) Michael P. Schwartz et al.   PLoS One

Facile preparation of photodegradable hydrogels by photopolymerization

(2013) Chang Seok Ki et al.   POLYMER

Extracellular matrix protein adsorption to phosphate-functionalized gels from serum promotes osteogenic differentiation of human mesenchymal stem cells

(2012) Navakanth R. Gandavarapu et al.   Acta Biomaterialia

Cross-Linking and Degradation of Step-Growth Hydrogels Formed by Thiol–Ene Photoclick Chemistry

(2012) Han Shih et al.   BIOMACROMOLECULES

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

(2011) Matthew W. Conklin et al.   AMERICAN JOURNAL OF PATHOLOGY

PEG hydrogels formed by thiol-ene photo-click chemistry and their effect on the formation and recovery of insulin-secreting cell spheroids

(2011) Chien-Chi Lin et al.   BIOMATERIALS

The performance of human mesenchymal stem cells encapsulated in cell-degradable polymer-peptide hydrogels

(2011) Sarah B. Anderson et al.   BIOMATERIALS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

(2011) T. R. Cox et al.   Disease Models & Mechanisms

Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling

(2011) P. P. Provenzano et al.   JOURNAL OF CELL SCIENCE

Manipulation of miRNA activity accelerates osteogenic differentiation of hMSCs in engineered 3D scaffolds

(2011) Peter D. Mariner et al.   Journal of Tissue Engineering and Regenerative Medicine

Thiol-Ene Click Chemistry

(2010) Charles E. Hoyle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biomimetic hydrogels with pro-angiogenic properties

(2010) James J. Moon et al.   BIOMATERIALS

A Model of Fibroblast Motility on Substrates with Different Rigidities

(2010) Irina V. Dokukina et al.   BIOPHYSICAL JOURNAL

A distinctive role for focal adhesion proteins in three-dimensional cell motility

(2010) Stephanie I. Fraley et al.   NATURE CELL BIOLOGY

Matrigel: A complex protein mixture required for optimal growth of cell culture

(2010) Chris S. Hughes et al.   PROTEOMICS

Forcing form and function: biomechanical regulation of tumor evolution

(2010) Hongmei Yu et al.   TRENDS IN CELL BIOLOGY

A Versatile Synthetic Extracellular Matrix Mimic via Thiol-Norbornene Photopolymerization

(2009) Benjamin D. Fairbanks et al.   ADVANCED MATERIALS

Characterization of valvular interstitial cell function in three dimensional matrix metalloproteinase degradable PEG hydrogels

(2009) Julie A. Benton et al.   BIOMATERIALS

Photoinitiated polymerization of PEG-diacrylate with lithium phenyl-2,4,6-trimethylbenzoylphosphinate: polymerization rate and cytocompatibility

(2009) Benjamin D. Fairbanks et al.   BIOMATERIALS

Probing cellular mechanobiology in three-dimensional culture with collagen–agarose matrices

(2009) Theresa A. Ulrich et al.   BIOMATERIALS

In situ elasticity modulation with dynamic substrates to direct cell phenotype

(2009) April M. Kloxin et al.   BIOMATERIALS

Elastic Moduli of Collagen Gels Can Be Predicted from Two-Dimensional Confocal Microscopy

(2009) Ya-li Yang et al.   BIOPHYSICAL JOURNAL

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

A synthetic strategy for mimicking the extracellular matrix provides new insight about tumor cell migration

(2009) Michael P. Schwartz et al.   Integrative Biology

Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited

(2009) Farideh Sabeh et al.   JOURNAL OF CELL BIOLOGY

Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments

(2009) Cole A. DeForest et al.   NATURE MATERIALS

Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates

(2009) D Yamazaki et al.   ONCOGENE

Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage

(2009) P P Provenzano et al.   ONCOGENE

Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties

(2009) April M. Kloxin et al.   SCIENCE

Guiding cell migration in 3D: A collagen matrix with graded directional stiffness

(2009) Ektoras Hadjipanayi et al.   CELL MOTILITY AND THE CYTOSKELETON

Three-Dimensional Biochemical Patterning of Click-Based Composite Hydrogels via Thiolene Photopolymerization

(2008) Brian D. Polizzotti et al.   BIOMACROMOLECULES

Durotaxis as an elastic stability phenomenon

(2008) Konstantinos A. Lazopoulos et al.   JOURNAL OF BIOMECHANICS

Effects of PEG hydrogel crosslinking density on protein diffusion and encapsulated islet survival and function

(2008) Laney M. Weber et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Small functional groups for controlled differentiation of hydrogel-encapsulated human mesenchymal stem cells

(2008) Danielle S. W. Benoit et al.   NATURE MATERIALS