Fibroblast growth factor 21 facilitates peripheral nerve regeneration through suppressing oxidative damage and autophagic cell death

Heparin-Poloxamer Thermosensitive Hydrogel Loaded with bFGF and NGF Enhances Peripheral Nerve Regeneration in Diabetic Rats

(2018) Rui Li et al.   BIOMATERIALS

FGF21 Protects the Blood–Brain Barrier by Upregulating PPARγ via FGFR1/β-klotho after Traumatic Brain Injury

(2018) Jun Chen et al.   JOURNAL OF NEUROTRAUMA

Honokiol induces apoptosis and autophagy via the ROS/ERK1/2 signaling pathway in human osteosarcoma cells in vitro and in vivo

(2018) Kangmao Huang et al.   Cell Death & Disease

Mesencephalic astrocyte-derived neurotrophic factor alleviated 6-OHDA-induced cell damage via ROS-AMPK/mTOR mediated autophagic inhibition

(2017) Jingxing Zhang et al.   EXPERIMENTAL GERONTOLOGY

Single injection of a novel nerve growth factor coacervate improves structural and functional regeneration after sciatic nerve injury in adult rats

(2017) Rui Li et al.   EXPERIMENTAL NEUROLOGY

Peripherally derived FGF21 promotes remyelination in the central nervous system

(2017) Mariko Kuroda et al.   JOURNAL OF CLINICAL INVESTIGATION

NGF Attenuates High Glucose-Induced ER Stress, Preventing Schwann Cell Apoptosis by Activating the PI3K/Akt/GSK3β and ERK1/2 Pathways

(2017) Rui Li et al.   NEUROCHEMICAL RESEARCH

Fibroblast growth factor 21 and its novel association with oxidative stress

(2017) Miguel Ángel Gómez-Sámano et al.   Redox Biology

Effect of Frankincense Extract on Nerve Recovery in the Rat Sciatic Nerve Damage Model

(2016) Xiaowen Jiang et al.   Evidence-based Complementary and Alternative Medicine

Up-regulation of Nrf2 is involved in FGF21-mediated fenofibrate protection against type 1 diabetic nephropathy

(2016) Yanli Cheng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fibroblast growth factor 21 (FGF21) inhibits macrophage-mediated inflammation by activating Nrf2 and suppressing the NF-κB signaling pathway

(2016) Yinhang Yu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Association Between Serum Fibroblast Growth Factor 21 and Mortality Among Patients With Coronary Artery Disease

(2016) Qing Li et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Autophagy Promotes Peripheral Nerve Regeneration and Motor Recovery Following Sciatic Nerve Crush Injury in Rats

(2016) Hai-cheng Huang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Autophagy activation involved in hypoxic-ischemic brain injury induces cognitive and memory impairment in neonatal rats

(2016) Ying Xu et al.   JOURNAL OF NEUROCHEMISTRY

Sesame oil improves functional recovery by attenuating nerve oxidative stress in a mouse model of acute peripheral nerve injury: role of Nrf-2

(2016) Che-Chia Hsu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Role of macrophages in Wallerian degeneration and axonal regeneration after peripheral nerve injury

(2015) Peiwen Chen et al.   ACTA NEUROPATHOLOGICA

The Role of Schwann Cell-Axon Interaction in Peripheral Nerve Regeneration

(2015) Uk Namgung   CELLS TISSUES ORGANS

Melatonin Leads to Axonal Regeneration, Reduction in Oxidative Stress, and Improved Functional Recovery Following Sciatic Nerve Injury

(2015) Yasemin Kaya et al.   CURRENT NEUROVASCULAR RESEARCH

Oxidative stress in myelin sheath: The other face of the extramitochondrial oxidative phosphorylation ability

(2015) S. Ravera et al.   FREE RADICAL RESEARCH

Autophagic myelin destruction by schwann cells during wallerian degeneration and segmental demyelination

(2015) So Young Jang et al.   GLIA

New insights on schwann cell development

(2015) Kelly R. Monk et al.   GLIA

Neuronal death after perinatal cerebral hypoxia-ischemia: Focus on autophagy—mediated cell death

(2015) C. Descloux et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

FGF21 as a mediator of adaptive responses to stress and metabolic benefits of anti-diabetic drugs

(2015) K. H. Kim et al.   JOURNAL OF ENDOCRINOLOGY

Fibroblast growth factor (FGF21) protects mouse liver against d-galactose-induced oxidative stress and apoptosis via activating Nrf2 and PI3K/Akt pathways

(2015) Yinhang Yu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Fibroblast growth factor 21 protects mouse brain against d-galactose induced aging via suppression of oxidative stress response and advanced glycation end products formation

(2015) Yinhang Yu et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Jinmaitong decreases sciatic nerve DNA oxidative damage and apoptosis in a streptozotocin-induced diabetic rat model

(2015) DE-HAI YIN et al.   Experimental and Therapeutic Medicine

Oxidative Stress, Redox Signaling, and Autophagy: Cell Death Versus Survival

(2014) Juliana Navarro-Yepes et al.   ANTIOXIDANTS & REDOX SIGNALING

Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury

(2014) Chinmoy Sarkar et al.   Autophagy

Autophagy suppression by exercise pretreatment and p38 inhibition is neuroprotective in cerebral ischemia

(2014) Li Zhang et al.   BRAIN RESEARCH

Fibroblast growth factor 21 protects the heart from oxidative stress

(2014) Anna Planavila et al.   CARDIOVASCULAR RESEARCH

Autosis and autophagic cell death: the dark side of autophagy

(2014) Y Liu et al.   CELL DEATH AND DIFFERENTIATION

Effects of dextromethorphan on glial cell function: Proliferation, maturation, and protection from cytotoxic molecules

(2014) Robert P. Lisak et al.   GLIA

Schwann cells transduced with a lentiviral vector encoding Fgf-2 promote motor neuron regeneration following sciatic nerve injury

(2014) Ilary Allodi et al.   GLIA

Selenium suppresses oxidative-stress-enhanced vascular smooth muscle cell calcification by inhibiting the activation of the PI3K/AKT and ERK signaling pathways and endoplasmic reticulum stress

(2014) Hongmei Liu et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

FGF-21, a novel metabolic regulator, has a robust neuroprotective role and is markedly elevated in neurons by mood stabilizers

(2014) Y Leng et al.   MOLECULAR PSYCHIATRY

Oxidative stress and nerve damage: Role in chemotherapy induced peripheral neuropathy

(2014) Aparna Areti et al.   Redox Biology

Intracellular reactive oxidative stress, cell proliferation and apoptosis of Schwann cells on carbon nanofibrous substrates

(2013) Shilpee Jain et al.   BIOMATERIALS

Fibroblast growth factor receptors, developmental corruption and malignant disease

(2013) F. C. Kelleher et al.   CARCINOGENESIS

Fibroblast Growth Factor 21 (FGF21) and Glucagon-Like Peptide 1 Contribute to Diabetes Resistance in Glucagon Receptor-Deficient Mice

(2013) B. A. Omar et al.   DIABETES

Increased miR-195 aggravates neuropathic pain by inhibiting autophagy following peripheral nerve injury

(2013) Guodong Shi et al.   GLIA

The Ras GTPase-activating-like Protein IQGAP1 Mediates Nrf2 Protein Activation via the Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase (ERK) Kinase (MEK)-ERK Pathway

(2013) Ka Lung Cheung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metformin inhibits heme oxygenase-1 expression in cancer cells through inactivation of Raf-ERK-Nrf2 signaling and AMPK-independent pathways

(2013) Minh Truong Do et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Measurement of autophagy flux in the nervous system in vivo

(2013) K Castillo et al.   Cell Death & Disease

Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology

(2013) Huating Li et al.   Frontiers of Medicine

MAPK and JAK-STAT Signaling Pathways are Involved in the Oxidative Stress – Induced Decrease in Expression of Surfactant Protein Genes

(2012) Sang-Kyu Park et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Oxidative stress, neurodegeneration, and the balance of protein degradation and protein synthesis

(2012) Kalavathi Dasuri et al.   FREE RADICAL BIOLOGY AND MEDICINE

Bers-ERK Schwann Cells Coordinate Nerve Regeneration

(2012) Jason M. Newbern et al.   NEURON

Gemfibrozil Pretreatment Affecting Antioxidant Defense System and Inflammatory, but not Nrf-2 Signaling Pathways Resulted in Female Neuroprotection and Male Neurotoxicity in the Rat Models of Global Cerebral Ischemia–Reperfusion

(2012) Fatemeh Mohagheghi et al.   NEUROTOXICITY RESEARCH

Acetyl-L-carnitine-mediated neuroprotection during hypoxia is attributed to ERK1/2-Nrf2-regulated mitochondrial biosynthesis

(2011) Kalpana Barhwal Hota et al.   HIPPOCAMPUS

Simvastatin improves morphological and functional recovery of sciatic nerve injury in Wistar rats

(2011) A.M. Xavier et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury

(2011) Andrew D Gaudet et al.   Journal of Neuroinflammation

Upregulation of Heme Oxygenase-1 by Acteoside Through ERK and PI3 K/Akt Pathway Confer Neuroprotection Against Beta-Amyloid-Induced Neurotoxicity

(2011) Hong-Quan Wang et al.   NEUROTOXICITY RESEARCH

When NRF2 Talks, Who's Listening?

(2010) Nobunao Wakabayashi et al.   ANTIOXIDANTS & REDOX SIGNALING

Cancer Chemoprevention Mechanisms Mediated Through the Keap1–Nrf2 Pathway

(2010) John D. Hayes et al.   ANTIOXIDANTS & REDOX SIGNALING

Hormone-like (endocrine) Fgfs: their evolutionary history and roles in development, metabolism, and disease

(2010) Nobuyuki Itoh   CELL AND TISSUE RESEARCH

Roles of zinc and metallothionein-3 in oxidative stress-induced lysosomal dysfunction, cell death, and autophagy in neurons and astrocytes

(2010) Sook-Jeong Lee et al.   Molecular Brain

Artificial nerve tubes and their application for repair of peripheral nerve injury: an update of current concepts

(2008) Satoshi Ichihara et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Chemistry and Antihypertensive Effects of Tempol and Other Nitroxides

(2008) C. S. Wilcox et al.   PHARMACOLOGICAL REVIEWS

Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

(2007) Melissa R. Junttila et al.   FASEB JOURNAL