New insights on schwann cell development

Premigratory and Migratory Neural Crest Cells Are Multipotent In Vivo

(2015) Arianna Baggiolini et al.   Cell Stem Cell

Transcription factors Sox10 and Sox2 functionally interact with positive transcription elongation factor b in Schwann cells

(2015) Juliane Arter et al.   JOURNAL OF NEUROCHEMISTRY

Axonal and Schwann Cell BACE1 Is Equally Required for Remyelination of Peripheral Nerves

(2015) X. Hu et al.   JOURNAL OF NEUROSCIENCE

The Adhesion GPCR GPR126 Has Distinct, Domain-Dependent Functions in Schwann Cell Development Mediated by Interaction with Laminin-211

(2015) Sarah C. Petersen et al.   NEURON

Profilin 1 is required for peripheral nervous system myelination

(2014) L. Montani et al.   DEVELOPMENT

Functional phylogenetic analysis of LGI proteins identifies an interaction motif crucial for myelination

(2014) L. Kegel et al.   DEVELOPMENT

Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination

(2014) M. E. Sheean et al.   GENES & DEVELOPMENT

A role of peripheral myelin protein 2 in lipid homeostasis of myelinating schwann cells

(2014) Jennifer Zenker et al.   GLIA

Functionally distinct PI 3-kinase pathways regulate myelination in the peripheral nervous system

(2014) Bradley A. Heller et al.   JOURNAL OF CELL BIOLOGY

Peripheral nervous system plasmalogens regulate Schwann cell differentiation and myelination

(2014) Tiago Ferreira da Silva et al.   JOURNAL OF CLINICAL INVESTIGATION

HDAC1 and HDAC2 Control the Specification of Neural Crest Cells into Peripheral Glia

(2014) C. Jacob et al.   JOURNAL OF NEUROSCIENCE

Terminal Schwann Cells Participate in Neuromuscular Synapse Remodeling during Reinnervation following Nerve Injury

(2014) H. Kang et al.   JOURNAL OF NEUROSCIENCE

Metabolic regulator LKB1 is crucial for Schwann cell–mediated axon maintenance

(2014) Bogdan Beirowski et al.   NATURE NEUROSCIENCE

Prostaglandin D2 synthase/GPR44: a signaling axis in PNS myelination

(2014) Amelia Trimarco et al.   NATURE NEUROSCIENCE

Parasympathetic ganglia derive from Schwann cell precursors

(2014) I. Espinosa-Medina et al.   SCIENCE

Parasympathetic neurons originate from nerve-associated peripheral glial progenitors

(2014) V. Dyachuk et al.   SCIENCE

Type IV collagen is an activating ligand for the adhesion G protein-coupled receptor GPR126

(2014) K. J. Paavola et al.   Science Signaling

Phosphorylation of LKB1/Par-4 establishes Schwann cell polarity to initiate and control myelin extent

(2014) Yun-An A. Shen et al.   Nature Communications

A Tethered Agonist within the Ectodomain Activates the Adhesion G Protein-Coupled Receptors GPR126 and GPR133

(2014) Ines Liebscher et al.   Cell Reports

mTORC1 Controls PNS Myelination along the mTORC1-RXRγ-SREBP-Lipid Biosynthesis Axis in Schwann Cells

(2014) Camilla Norrmén et al.   Cell Reports

Progress in demystification of adhesion G protein-coupled receptors

(2013) Ines Liebscher et al.   BIOLOGICAL CHEMISTRY

Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination

(2013) Florence R. Fricker et al.   BRAIN

Signals regulating myelination in peripheral nerves and the Schwann cell response to injury

(2013) Thomas D Glenn et al.   CURRENT OPINION IN NEUROBIOLOGY

Analysis of Gpr126 function defines distinct mechanisms controlling the initiation and maturation of myelin

(2013) T. D. Glenn et al.   DEVELOPMENT

Cdc42 regulates schwann cell radial sorting and myelin sheath folding through NF2/merlin-dependent and independent signaling

(2013) Li Guo et al.   GLIA

Lysophosphatidic acid (LPA) and its receptor, LPA1, influence embryonic schwann cell migration, myelination, and cell-to-axon segregation

(2013) Brigitte Anliker et al.   GLIA

Sip1 mediates an E-cadherin-to-N-cadherin switch during cranial neural crest EMT

(2013) Crystal D. Rogers et al.   JOURNAL OF CELL BIOLOGY

Jab1 regulates Schwann cell proliferation and axonal sorting through p27

(2013) Emanuela Porrello et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activation of NF- B in Schwann Cells Is Dispensable for Myelination In Vivo

(2013) P. D. Morton et al.   JOURNAL OF NEUROSCIENCE

The Protein Kinase A Regulatory Subunit R1A (Prkar1a) Plays Critical Roles in Peripheral Nerve Development

(2013) L. Guo et al.   JOURNAL OF NEUROSCIENCE

Terminal Schwann Cells Participate in the Competition Underlying Neuromuscular Synapse Elimination

(2013) I. W. Smith et al.   JOURNAL OF NEUROSCIENCE

Sustained Activation of ERK1/2 MAPK in Oligodendrocytes and Schwann Cells Enhances Myelin Growth and Stimulates Oligodendrocyte Progenitor Expansion

(2013) A. Ishii et al.   JOURNAL OF NEUROSCIENCE

Genetic Deletion of Cadm4 Results in Myelin Abnormalities Resembling Charcot-Marie-Tooth Neuropathy

(2013) N. Golan et al.   JOURNAL OF NEUROSCIENCE

Gpr126 Functions in Schwann Cells to Control Differentiation and Myelination via G-Protein Activation

(2013) A. Mogha et al.   JOURNAL OF NEUROSCIENCE

NF- B Forms a Complex with the Chromatin Remodeler BRG1 to Regulate Schwann Cell Differentiation

(2013) A. S. Limpert et al.   JOURNAL OF NEUROSCIENCE

Dual Cleavage of Neuregulin 1 Type III by BACE1 and ADAM17 Liberates Its EGF-Like Domain and Allows Paracrine Signaling

(2013) D. Fleck et al.   JOURNAL OF NEUROSCIENCE

 6 1 and  7 1 Integrins Are Required in Schwann Cells to Sort Axons

(2013) M. Pellegatta et al.   JOURNAL OF NEUROSCIENCE

Clinical implications of genetic advances in Charcot–Marie–Tooth disease

(2013) Alexander M. Rossor et al.   Nature Reviews Neurology

Aberrant Schwann Cell Lipid Metabolism Linked to Mitochondrial Deficits Leads to Axon Degeneration and Neuropathy

(2013) Andreu Viader et al.   NEURON

SWI/SNF Enzymes Promote SOX10- Mediated Activation of Myelin Gene Expression

(2013) Himangi G. Marathe et al.   PLoS One

Wnt/Rspondin/ -catenin signals control axonal sorting and lineage progression in Schwann cell development

(2013) T. Grigoryan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sticky Signaling--Adhesion Class G Protein-Coupled Receptors Take the Stage

(2013) T. Langenhan et al.   Science Signaling

Current perspectives of the signaling pathways directing neural crest induction

(2012) Timothy J. Stuhlmiller et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Neural crest delamination and migration: From epithelium-to-mesenchyme transition to collective cell migration

(2012) Eric Theveneau et al.   DEVELOPMENTAL BIOLOGY

Chromatin-Remodeling Factor Brg1 Is Required for Schwann Cell Differentiation and Myelination

(2012) Matthias Weider et al.   DEVELOPMENTAL CELL

Genetic disruption ofPtenin a novel mouse model of tomaculous neuropathy

(2012) Sandra Goebbels et al.   EMBO Molecular Medicine

Regulation of Schwann cell differentiation and proliferation by the Pax-3 transcription factor

(2012) Robin D. S. Doddrell et al.   GLIA

Rac1 Controls Schwann Cell Myelination through cAMP and NF2/merlin

(2012) L. Guo et al.   JOURNAL OF NEUROSCIENCE

Arrest of Myelination and Reduced Axon Growth When Schwann Cells Lack mTOR

(2012) D. L. Sherman et al.   JOURNAL OF NEUROSCIENCE

p38 MAPK Activation Promotes Denervated Schwann Cell Phenotype and Functions as a Negative Regulator of Schwann Cell Differentiation and Myelination

(2012) D. P. Yang et al.   JOURNAL OF NEUROSCIENCE

The Nucleosome Remodeling and Deacetylase Chromatin Remodeling (NuRD) Complex Is Required for Peripheral Nerve Myelination

(2012) H. Hung et al.   JOURNAL OF NEUROSCIENCE

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

A role for Schwann cell–derived neuregulin-1 in remyelination

(2012) Ruth M Stassart et al.   NATURE NEUROSCIENCE

A Central Role for the ERK-Signaling Pathway in Controlling Schwann Cell Plasticity and Peripheral Nerve Regeneration In Vivo

(2012) Ilaria Napoli et al.   NEURON

Myotubularin phosphoinositide phosphatases: cellular functions and disease pathophysiology

(2012) Karim Hnia et al.   TRENDS IN MOLECULAR MEDICINE

Reversing the Outcome of Synapse Elimination at Developing Neuromuscular Junctions In Vivo: Evidence for Synaptic Competition and Its Mechanism

(2012) Stephen G. Turney et al.   PLOS BIOLOGY

Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis

(2011) Brady K Atwood et al.   BMC GENOMICS

Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche

(2011) Satoshi Yamazaki et al.   CELL

N-WASp is required for Schwann cell cytoskeletal dynamics, normal myelin gene expression and peripheral nerve myelination

(2011) Fuzi Jin et al.   DEVELOPMENT

Non-redundant function of dystroglycan and  1 integrins in radial sorting of axons

(2011) C. Berti et al.   DEVELOPMENT

Neuronal Neuregulin 1 type III directs Schwann cell migration

(2011) J. R. Perlin et al.   DEVELOPMENT

Gpr126 is essential for peripheral nerve development and myelination in mammals

(2011) K. R. Monk et al.   DEVELOPMENT

Sox10 is required for Schwann-cell homeostasis and myelin maintenance in the adult peripheral nerve

(2011) Magdalena Bremer et al.   GLIA

Mouse schwann cells need both NRG1 and cyclic AMP to myelinate

(2011) Peter Arthur-Farraj et al.   GLIA

Cleavage of Neuregulin-1 by BACE1 or ADAM10 Protein Produces Differential Effects on Myelination

(2011) Xiaoyang Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-WASP is required for membrane wrapping and myelination by Schwann cells

(2011) Nurit Novak et al.   JOURNAL OF CELL BIOLOGY

The Cyclin-Dependent Kinase Inhibitor p27Kip1 is a Positive Regulator of Schwann Cell Differentiation In Vitro

(2011) Honghui Li et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Assessing the Role of the Cadherin/Catenin Complex at the Schwann Cell-Axon Interface and in the Initiation of Myelination

(2011) K. A. Lewallen et al.   JOURNAL OF NEUROSCIENCE

Functional Dissection of the Oct6 Schwann Cell Enhancer Reveals an Essential Role for Dimeric Sox10 Binding

(2011) N. B. Jagalur et al.   JOURNAL OF NEUROSCIENCE

Schwann Cell Mitochondrial Metabolism Supports Long-Term Axonal Survival and Peripheral Nerve Function

(2011) A. Viader et al.   JOURNAL OF NEUROSCIENCE

TACE (ADAM17) inhibits Schwann cell myelination

(2011) Rosa La Marca et al.   NATURE NEUROSCIENCE

HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination

(2011) Ying Chen et al.   NATURE NEUROSCIENCE

HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells

(2011) Claire Jacob et al.   NATURE NEUROSCIENCE

Specific Functions for ERK/MAPK Signaling during PNS Development

(2011) Jason M. Newbern et al.   NEURON

Molecular mechanisms regulating myelination in the peripheral nervous system

(2011) Jorge A. Pereira et al.   TRENDS IN NEUROSCIENCES

EphB Signaling Directs Peripheral Nerve Regeneration through Sox2-Dependent Schwann Cell Sorting

(2010) Simona Parrinello et al.   CELL

Schwann cells reposition a peripheral nerve to isolate it from postembryonic remodeling of its targets

(2010) A. R. Raphael et al.   DEVELOPMENT

Axonal Neuregulin 1 Type III Activates NF-κB in Schwann Cells during Myelin Formation

(2010) Allison S. Limpert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models

(2010) Roman Chrast et al.   JOURNAL OF LIPID RESEARCH

Lack of Collagen XV Impairs Peripheral Nerve Maturation and, When Combined with Laminin-411 Deficiency, Leads to Basement Membrane Abnormalities and Sensorimotor Dysfunction

(2010) K. Rasi et al.   JOURNAL OF NEUROSCIENCE

Lgi4 Promotes the Proliferation and Differentiation of Glial Lineage Cells throughout the Developing Peripheral Nervous System

(2010) J. Nishino et al.   JOURNAL OF NEUROSCIENCE

Elevated Phosphatidylinositol 3,4,5-Trisphosphate in Glia Triggers Cell-Autonomous Membrane Wrapping and Myelination

(2010) S. Goebbels et al.   JOURNAL OF NEUROSCIENCE

MicroRNA-Deficient Schwann Cells Display Congenital Hypomyelination

(2010) B. Yun et al.   JOURNAL OF NEUROSCIENCE

Dicer in Schwann Cells Is Required for Myelination and Axonal Integrity

(2010) J. A. Pereira et al.   JOURNAL OF NEUROSCIENCE

Yy1 as a molecular link between neuregulin and transcriptional modulation of peripheral myelination

(2010) Ye He et al.   NATURE NEUROSCIENCE

Signals to promote myelin formation and repair

(2010) Carla Taveggia et al.   Nature Reviews Neurology

Nrg1/ErbB signaling networks in Schwann cell development and myelination

(2010) Jason Newbern et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The effects of α-secretase ADAM10 on the proteolysis of neuregulin-1

(2009) Christian Freese et al.   FEBS Journal

Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers

(2009) Fanny Coulpier et al.   GLIA

Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system

(2009) Jorge A. Pereira et al.   JOURNAL OF CELL BIOLOGY

Sensory Axon-Derived Neuregulin-1 Is Required for Axoglial Signaling and Normal Sensory Function But Not for Long-Term Axon Maintenance

(2009) F. R. Fricker et al.   JOURNAL OF NEUROSCIENCE

Cholesterol Regulates the Endoplasmic Reticulum Exit of the Major Membrane Protein P0 Required for Peripheral Myelin Compaction

(2009) G. Saher et al.   JOURNAL OF NEUROSCIENCE

Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity

(2009) Ashwin Woodhoo et al.   NATURE NEUROSCIENCE

SCAP is required for timely and proper myelin membrane synthesis

(2009) Mark H. G. Verheijen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development

(2009) K. S. Grossmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Went Fishing, Caught a Snake

(2009) D. Meijer   SCIENCE

Calcineurin/NFAT Signaling Is Required for Neuregulin-Regulated Schwann Cell Differentiation

(2009) S.-C. Kao et al.   SCIENCE

A G Protein-Coupled Receptor Is Essential for Schwann Cells to Initiate Myelination

(2009) K. R. Monk et al.   SCIENCE

Genetic deletion of BACE1 in mice affects remyelination of sciatic nerves

(2008) Xiangyou Hu et al.   FASEB JOURNAL

Phosphatidic acid mediates demyelination in Lpin1 mutant mice

(2008) K. Nadra et al.   GENES & DEVELOPMENT

Molecular mechanisms of inherited demyelinating neuropathies

(2008) Steven S. Scherer et al.   GLIA

Biology and pathology of nonmyelinating Schwann cells

(2008) John W. Griffin et al.   GLIA

The molecular machinery of myelin gene transcription in Schwann cells

(2008) John Svaren et al.   GLIA

Development of the Schwann cell lineage: From the neural crest to the myelinated nerve

(2008) Ashwin Woodhoo et al.   GLIA

Non-antagonistic relationship between mitogenic factors and cAMP in adult Schwann cell re-differentiation

(2008) Paula V. Monje et al.   GLIA

Roles of Meltrin-β/ADAM19 in Progression of Schwann Cell Differentiation and Myelination during Sciatic Nerve Regeneration

(2008) Shuji Wakatsuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Active Gene Repression by the Egr2·NAB Complex during Peripheral Nerve Myelination

(2008) Gennifer M. Mager et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

c-Jun is a negative regulator of myelination

(2008) David B. Parkinson et al.   JOURNAL OF CELL BIOLOGY

A single point mutation in the LN domain of LAMA2 causes muscular dystrophy and peripheral amyelination

(2008) B. L. Patton et al.   JOURNAL OF CELL SCIENCE

Disruption of Krox20-Nab Interaction in the Mouse Leads to Peripheral Neuropathy with Biphasic Evolution

(2008) A. Desmazieres et al.   JOURNAL OF NEUROSCIENCE

Disruption of Nectin-Like 1 Cell Adhesion Molecule Leads to Delayed Axonal Myelination in the CNS

(2008) J. Park et al.   JOURNAL OF NEUROSCIENCE

A gene regulatory network orchestrates neural crest formation

(2008) Tatjana Sauka-Spengler et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Neuregulin 1 in neural development, synaptic plasticity and schizophrenia

(2008) Lin Mei et al.   NATURE REVIEWS NEUROSCIENCE