- Home
- Publications
- Publication Search
- Publication Details
Title
PGC-1α as a Pivotal Factor in Lipid and Metabolic Regulation
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 11, Pages 3447
Publisher
MDPI AG
Online
2018-11-05
DOI
10.3390/ijms19113447
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The role of cardiac energy metabolism in cardiac hypertrophy and failure
- (2017) Tomi Tuomainen et al. EXPERIMENTAL CELL RESEARCH
- Metabolic reprogramming and epithelial-to-mesenchymal transition in cancer
- (2017) Marco Sciacovelli et al. FEBS Journal
- Epithelial-to-Mesenchymal Transition: Epigenetic Reprogramming Driving Cellular Plasticity
- (2017) Nicolas Skrypek et al. TRENDS IN GENETICS
- Peroxisome proliferator-activated receptor gamma coactivator-1 alpha acts as a tumor suppressor in hepatocellular carcinoma
- (2017) Rui Liu et al. TUMOR BIOLOGY
- PGC-1α attenuates hydrogen peroxide-induced apoptotic cell death by upregulating Nrf-2 via GSK3β inactivation mediated by activated p38 in HK-2 Cells
- (2017) Hoon-In Choi et al. Scientific Reports
- The Implication of PGC-1α on Fatty Acid Transport across Plasma and Mitochondrial Membranes in the Insulin Sensitive Tissues
- (2017) Elżbieta Supruniuk et al. Frontiers in Physiology
- Bioenergetic Adaptations in Chemoresistant Ovarian Cancer Cells
- (2017) Sajad Dar et al. Scientific Reports
- EMT, cell plasticity and metastasis
- (2016) Christine L. Chaffer et al. CANCER AND METASTASIS REVIEWS
- A PGC1α-mediated transcriptional axis suppresses melanoma metastasis
- (2016) Chi Luo et al. NATURE
- The metabolic co-regulator PGC1α suppresses prostate cancer metastasis
- (2016) Veronica Torrano et al. NATURE CELL BIOLOGY
- Prognostic value of plasma levels of HIF-1a and PGC-1a in breast cancer
- (2016) Feng-Feng Cai et al. Oncotarget
- Adiponectin Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Remodeling through Nitric Oxide and the RhoA/ROCK Pathway
- (2016) Wared Nour-Eldine et al. Frontiers in Pharmacology
- PGC-1α dictates endothelial function through regulation of eNOS expression
- (2016) Siobhan M. Craige et al. Scientific Reports
- Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry
- (2015) Mark P. Jedrychowski et al. Cell Metabolism
- Maintaining Ancient Organelles: Mitochondrial Biogenesis and Maturation
- (2015) R. B. Vega et al. CIRCULATION RESEARCH
- Circulating irisin levels are associated with lipid and uric acid metabolism in a Chinese population
- (2015) Shanshan Tang et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes
- (2015) T.-Y. Liu et al. CLINICAL SCIENCE
- ACE2 deficiency worsens epicardial adipose tissue inflammation and cardiac dysfunction in response to diet-induced obesity
- (2015) Vaibhav B. Patel et al. DIABETES
- Metabolic roles of PGC-1α and its implications for type 2 diabetes
- (2015) A. Besseiche et al. DIABETES & METABOLISM
- Inhibition of myostatin in mice improves insulin sensitivity via irisin-mediated cross talk between muscle and adipose tissues
- (2015) J Dong et al. INTERNATIONAL JOURNAL OF OBESITY
- Irisin improves fatty acid oxidation and glucose utilization in type 2 diabetes by regulating the AMPK signaling pathway
- (2015) C Xin et al. INTERNATIONAL JOURNAL OF OBESITY
- Overexpression of PGC-1α enhances cell proliferation and tumorigenesis of HEK293 cells through the upregulation of Sp1 and Acyl-CoA binding protein
- (2015) SUNG-WON SHIN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Metabolic pathways promoting cancer cell survival and growth
- (2015) Lindsey K. Boroughs et al. NATURE CELL BIOLOGY
- Mitochondria: a therapeutic target in acute kidney injury
- (2015) Yu Ishimoto et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Metabolomic Analysis of the Skeletal Muscle of Mice Overexpressing PGC-1α
- (2015) Yukino Hatazawa et al. PLoS One
- Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans
- (2014) Paul Lee et al. Cell Metabolism
- Plasma irisin levels progressively increase in response to increasing exercise workloads in young, healthy, active subjects
- (2014) Stella S Daskalopoulou et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Leptin administration activates irisin-induced myogenesis via nitric oxide-dependent mechanisms, but reduces its effect on subcutaneous fat browning in mice
- (2014) A Rodríguez et al. INTERNATIONAL JOURNAL OF OBESITY
- Irisin stimulates muscle growth-related genes and regulates adipocyte differentiation and metabolism in humans
- (2014) J Y Huh et al. INTERNATIONAL JOURNAL OF OBESITY
- Hypoxic Induction of Vascular Endothelial Growth Factor (VEGF) and Angiogenesis in Muscle by Truncated Peroxisome Proliferator-activated Receptor γ Coactivator (PGC)-1α
- (2014) Robyn Thom et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Exercise-Induced Irisin Secretion Is Independent of Age or Fitness Level and Increased Irisin May Directly Modulate Muscle Metabolism Through AMPK Activation
- (2014) Joo Young Huh et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Conditional Knockout of Proximal Tubule Mitofusin 2 Accelerates Recovery and Improves Survival after Renal Ischemia
- (2014) J. M. Gall et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis
- (2014) Valerie S. LeBleu et al. NATURE CELL BIOLOGY
- Expression of Mitochondrial Regulators PGC1α and TFAM as Putative Markers of Subtype and Chemoresistance in Epithelial Ovarian Carcinoma
- (2014) Marike Gabrielson et al. PLoS One
- Proteomic signatures associated with p53 mutational status in lung adenocarcinoma
- (2014) Ayumu Taguchi et al. PROTEOMICS
- Recent Insights in the Paracrine Modulation of Cardiomyocyte Contractility by Cardiac Endothelial Cells
- (2014) Jacques Noireaud et al. Biomed Research International
- Epicardial and Perivascular Adipose Tissues and Their Influence on Cardiovascular Disease: Basic Mechanisms and Clinical Associations
- (2014) Timothy P. Fitzgibbons et al. Journal of the American Heart Association
- Activation of ERK accelerates repair of renal tubular epithelial cells, whereas it inhibits progression of fibrosis following ischemia/reperfusion injury
- (2013) Hee-Seong Jang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- PGC1α Expression Defines a Subset of Human Melanoma Tumors with Increased Mitochondrial Capacity and Resistance to Oxidative Stress
- (2013) Francisca Vazquez et al. CANCER CELL
- Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF
- (2013) Rizwan Haq et al. CANCER CELL
- Cancer as a metabolic disease: implications for novel therapeutics
- (2013) T. N. Seyfried et al. CARCINOGENESIS
- Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway
- (2013) Christiane D. Wrann et al. Cell Metabolism
- Cellular Fatty Acid Metabolism and Cancer
- (2013) Erin Currie et al. Cell Metabolism
- Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling
- (2013) Y. Zhang et al. DIABETES
- Myostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1α-Fndc5 pathway in muscle
- (2013) Tizhong Shan et al. FASEB JOURNAL
- Role of mitofusin 2 (Mfn2) in controlling cellular proliferation
- (2013) Kuang-Hueih Chen et al. FASEB JOURNAL
- Glutamine and cancer: cell biology, physiology, and clinical opportunities
- (2013) Christopher T. Hensley et al. JOURNAL OF CLINICAL INVESTIGATION
- AMP-activated protein kinase is required for exercise-induced peroxisome proliferator-activated receptor γ co-activator 1α translocation to subsarcolemmal mitochondria in skeletal muscle
- (2013) Brennan K. Smith et al. JOURNAL OF PHYSIOLOGY-LONDON
- Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch
- (2013) J B Tennakoon et al. ONCOGENE
- Cellular cross-talk between epicardial adipose tissue and myocardium in relation to the pathogenesis of cardiovascular disease
- (2012) Sam Cherian et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- PGC-1α overexpression results in increased hepatic fatty acid oxidation with reduced triacylglycerol accumulation and secretion
- (2012) E. Matthew Morris et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- The role of PGC-1 coactivators in aging skeletal muscle and heart
- (2012) Lloye M. Dillon et al. IUBMB LIFE
- Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injury
- (2012) Jianchun Chen et al. KIDNEY INTERNATIONAL
- A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
- (2012) Pontus Boström et al. NATURE
- Role of PGC-1α in exercise and fasting-induced adaptations in mouse liver
- (2011) Tobias Nørresø Haase et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- PGC1 Promotes Tumor Growth by Inducing Gene Expression Programs Supporting Lipogenesis
- (2011) K. Bhalla et al. CANCER RESEARCH
- White to Brown Fat Phenotypic Switch Induced by Genetic and Environmental Activation of a Hypothalamic-Adipocyte Axis
- (2011) Lei Cao et al. Cell Metabolism
- Inhibition of myostatin protects against diet-induced obesity by enhancing fatty acid oxidation and promoting a brown adipose phenotype in mice
- (2011) C. Zhang et al. DIABETOLOGIA
- PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice
- (2011) Mei Tran et al. JOURNAL OF CLINICAL INVESTIGATION
- Mitochondrial Biogenesis in Kidney Disease
- (2011) J. M. Weinberg JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Fatty liver is associated with impaired activity of PPARγ-coactivator 1α (PGC1α) and mitochondrial biogenesis in mice
- (2011) Michal Aharoni-Simon et al. LABORATORY INVESTIGATION
- Expression and Function of Myostatin in Obesity, Diabetes, and Exercise Adaptation
- (2011) DAVID L. ALLEN et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Increases in mitochondrial biogenesis impair carcinogenesis at multiple levels
- (2011) Xiao Wang et al. Molecular Oncology
- Peroxisome proliferator-activated receptor- coactivator 1- (PGC1 ) is a metabolic regulator of intestinal epithelial cell fate
- (2011) I. D'Errico et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epicardial adipose tissue: emerging physiological, pathophysiological and clinical features
- (2011) Gianluca Iacobellis et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis
- (2010) Craig Brooks et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- PGC-1 Coactivators in Cardiac Development and Disease
- (2010) Glenn C. Rowe et al. CIRCULATION RESEARCH
- Peroxisome Proliferator-activated Receptor γ Coactivator 1α (PGC-1α) Promotes Skeletal Muscle Lipid Refuelingin Vivoby Activatingde NovoLipogenesis and the Pentose Phosphate Pathway
- (2010) Serge Summermatter et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Energy Metabolic Phenotype of the Cardiomyocyte During Development, Differentiation, and Postnatal Maturation
- (2010) Gary D Lopaschuk et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- PGC-1 regulates a HIF2 -dependent switch in skeletal muscle fiber types
- (2010) K. A. Rasbach et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of homocysteine homeostasis through the transcriptional coactivator PGC-1α
- (2009) Siming Li et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Dual modulation of both lipid oxidation and synthesis by peroxisome proliferator-activated receptor-γ coactivator-1α and -1β in cultured myotubes
- (2009) Daniel O. Espinoza et al. FASEB JOURNAL
- Uncoupling Protein-1 and Related Messenger Ribonucleic Acids in Human Epicardial and Other Adipose Tissues: Epicardial Fat Functioning as Brown Fat
- (2009) Harold S. Sacks et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models
- (2009) Craig Brooks et al. JOURNAL OF CLINICAL INVESTIGATION
- Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Interacts with the Androgen Receptor (AR) and Promotes Prostate Cancer Cell Growth by Activating the AR
- (2009) Masaki Shiota et al. MOLECULAR ENDOCRINOLOGY
- Epicardial and Pericardial Fat: Close, but Very Different
- (2009) Gianluca Iacobellis Obesity
- Myostatin Inhibition in Muscle, but Not Adipose Tissue, Decreases Fat Mass and Improves Insulin Sensitivity
- (2009) Tingqing Guo et al. PLoS One
- The transcriptional coactivator PGC-1α mediates exercise-induced angiogenesis in skeletal muscle
- (2009) Jessica Chinsomboon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epicardial Adipose Tissue Adiponectin Expression is Related to Intracoronary Adiponectin Levels
- (2008) G. Iacobellis et al. HORMONE AND METABOLIC RESEARCH
- Muscle-specific expression of PPARγ coactivator-1α improves exercise performance and increases peak oxygen uptake
- (2008) Jennifer A. Calvo et al. JOURNAL OF APPLIED PHYSIOLOGY
- Suppression of Lipopolysaccharide-stimulated Tumor Necrosis Factor-α Production by Adiponectin Is Mediated by Transcriptional and Post-transcriptional Mechanisms
- (2008) Pil-Hoon Park et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Paradoxical effects of increased expression of PGC-1 on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism
- (2008) C. S. Choi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now