标题
PGC-1α as a Pivotal Factor in Lipid and Metabolic Regulation
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 11, Pages 3447
出版商
MDPI AG
发表日期
2018-11-05
DOI
10.3390/ijms19113447
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- The role of cardiac energy metabolism in cardiac hypertrophy and failure
- (2017) Tomi Tuomainen et al. EXPERIMENTAL CELL RESEARCH
- Metabolic reprogramming and epithelial-to-mesenchymal transition in cancer
- (2017) Marco Sciacovelli et al. FEBS Journal
- Epithelial-to-Mesenchymal Transition: Epigenetic Reprogramming Driving Cellular Plasticity
- (2017) Nicolas Skrypek et al. TRENDS IN GENETICS
- Peroxisome proliferator-activated receptor gamma coactivator-1 alpha acts as a tumor suppressor in hepatocellular carcinoma
- (2017) Rui Liu et al. TUMOR BIOLOGY
- PGC-1α attenuates hydrogen peroxide-induced apoptotic cell death by upregulating Nrf-2 via GSK3β inactivation mediated by activated p38 in HK-2 Cells
- (2017) Hoon-In Choi et al. Scientific Reports
- The Implication of PGC-1α on Fatty Acid Transport across Plasma and Mitochondrial Membranes in the Insulin Sensitive Tissues
- (2017) Elżbieta Supruniuk et al. Frontiers in Physiology
- Bioenergetic Adaptations in Chemoresistant Ovarian Cancer Cells
- (2017) Sajad Dar et al. Scientific Reports
- EMT, cell plasticity and metastasis
- (2016) Christine L. Chaffer et al. CANCER AND METASTASIS REVIEWS
- A PGC1α-mediated transcriptional axis suppresses melanoma metastasis
- (2016) Chi Luo et al. NATURE
- The metabolic co-regulator PGC1α suppresses prostate cancer metastasis
- (2016) Veronica Torrano et al. NATURE CELL BIOLOGY
- Prognostic value of plasma levels of HIF-1a and PGC-1a in breast cancer
- (2016) Feng-Feng Cai et al. Oncotarget
- Adiponectin Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Remodeling through Nitric Oxide and the RhoA/ROCK Pathway
- (2016) Wared Nour-Eldine et al. Frontiers in Pharmacology
- PGC-1α dictates endothelial function through regulation of eNOS expression
- (2016) Siobhan M. Craige et al. Scientific Reports
- Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry
- (2015) Mark P. Jedrychowski et al. Cell Metabolism
- Maintaining Ancient Organelles: Mitochondrial Biogenesis and Maturation
- (2015) R. B. Vega et al. CIRCULATION RESEARCH
- Circulating irisin levels are associated with lipid and uric acid metabolism in a Chinese population
- (2015) Shanshan Tang et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes
- (2015) T.-Y. Liu et al. CLINICAL SCIENCE
- ACE2 deficiency worsens epicardial adipose tissue inflammation and cardiac dysfunction in response to diet-induced obesity
- (2015) Vaibhav B. Patel et al. DIABETES
- Metabolic roles of PGC-1α and its implications for type 2 diabetes
- (2015) A. Besseiche et al. DIABETES & METABOLISM
- Inhibition of myostatin in mice improves insulin sensitivity via irisin-mediated cross talk between muscle and adipose tissues
- (2015) J Dong et al. INTERNATIONAL JOURNAL OF OBESITY
- Irisin improves fatty acid oxidation and glucose utilization in type 2 diabetes by regulating the AMPK signaling pathway
- (2015) C Xin et al. INTERNATIONAL JOURNAL OF OBESITY
- Overexpression of PGC-1α enhances cell proliferation and tumorigenesis of HEK293 cells through the upregulation of Sp1 and Acyl-CoA binding protein
- (2015) SUNG-WON SHIN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Metabolic pathways promoting cancer cell survival and growth
- (2015) Lindsey K. Boroughs et al. NATURE CELL BIOLOGY
- Mitochondria: a therapeutic target in acute kidney injury
- (2015) Yu Ishimoto et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Metabolomic Analysis of the Skeletal Muscle of Mice Overexpressing PGC-1α
- (2015) Yukino Hatazawa et al. PLoS One
- Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans
- (2014) Paul Lee et al. Cell Metabolism
- Plasma irisin levels progressively increase in response to increasing exercise workloads in young, healthy, active subjects
- (2014) Stella S Daskalopoulou et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Leptin administration activates irisin-induced myogenesis via nitric oxide-dependent mechanisms, but reduces its effect on subcutaneous fat browning in mice
- (2014) A Rodríguez et al. INTERNATIONAL JOURNAL OF OBESITY
- Irisin stimulates muscle growth-related genes and regulates adipocyte differentiation and metabolism in humans
- (2014) J Y Huh et al. INTERNATIONAL JOURNAL OF OBESITY
- Hypoxic Induction of Vascular Endothelial Growth Factor (VEGF) and Angiogenesis in Muscle by Truncated Peroxisome Proliferator-activated Receptor γ Coactivator (PGC)-1α
- (2014) Robyn Thom et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Exercise-Induced Irisin Secretion Is Independent of Age or Fitness Level and Increased Irisin May Directly Modulate Muscle Metabolism Through AMPK Activation
- (2014) Joo Young Huh et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Conditional Knockout of Proximal Tubule Mitofusin 2 Accelerates Recovery and Improves Survival after Renal Ischemia
- (2014) J. M. Gall et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis
- (2014) Valerie S. LeBleu et al. NATURE CELL BIOLOGY
- Expression of Mitochondrial Regulators PGC1α and TFAM as Putative Markers of Subtype and Chemoresistance in Epithelial Ovarian Carcinoma
- (2014) Marike Gabrielson et al. PLoS One
- Proteomic signatures associated with p53 mutational status in lung adenocarcinoma
- (2014) Ayumu Taguchi et al. PROTEOMICS
- Recent Insights in the Paracrine Modulation of Cardiomyocyte Contractility by Cardiac Endothelial Cells
- (2014) Jacques Noireaud et al. Biomed Research International
- Epicardial and Perivascular Adipose Tissues and Their Influence on Cardiovascular Disease: Basic Mechanisms and Clinical Associations
- (2014) Timothy P. Fitzgibbons et al. Journal of the American Heart Association
- Activation of ERK accelerates repair of renal tubular epithelial cells, whereas it inhibits progression of fibrosis following ischemia/reperfusion injury
- (2013) Hee-Seong Jang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- PGC1α Expression Defines a Subset of Human Melanoma Tumors with Increased Mitochondrial Capacity and Resistance to Oxidative Stress
- (2013) Francisca Vazquez et al. CANCER CELL
- Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF
- (2013) Rizwan Haq et al. CANCER CELL
- Cancer as a metabolic disease: implications for novel therapeutics
- (2013) T. N. Seyfried et al. CARCINOGENESIS
- Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway
- (2013) Christiane D. Wrann et al. Cell Metabolism
- Cellular Fatty Acid Metabolism and Cancer
- (2013) Erin Currie et al. Cell Metabolism
- Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling
- (2013) Y. Zhang et al. DIABETES
- Myostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1α-Fndc5 pathway in muscle
- (2013) Tizhong Shan et al. FASEB JOURNAL
- Role of mitofusin 2 (Mfn2) in controlling cellular proliferation
- (2013) Kuang-Hueih Chen et al. FASEB JOURNAL
- Glutamine and cancer: cell biology, physiology, and clinical opportunities
- (2013) Christopher T. Hensley et al. JOURNAL OF CLINICAL INVESTIGATION
- AMP-activated protein kinase is required for exercise-induced peroxisome proliferator-activated receptor γ co-activator 1α translocation to subsarcolemmal mitochondria in skeletal muscle
- (2013) Brennan K. Smith et al. JOURNAL OF PHYSIOLOGY-LONDON
- Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch
- (2013) J B Tennakoon et al. ONCOGENE
- Cellular cross-talk between epicardial adipose tissue and myocardium in relation to the pathogenesis of cardiovascular disease
- (2012) Sam Cherian et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- PGC-1α overexpression results in increased hepatic fatty acid oxidation with reduced triacylglycerol accumulation and secretion
- (2012) E. Matthew Morris et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- The role of PGC-1 coactivators in aging skeletal muscle and heart
- (2012) Lloye M. Dillon et al. IUBMB LIFE
- Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injury
- (2012) Jianchun Chen et al. KIDNEY INTERNATIONAL
- A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
- (2012) Pontus Boström et al. NATURE
- Role of PGC-1α in exercise and fasting-induced adaptations in mouse liver
- (2011) Tobias Nørresø Haase et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- PGC1 Promotes Tumor Growth by Inducing Gene Expression Programs Supporting Lipogenesis
- (2011) K. Bhalla et al. CANCER RESEARCH
- White to Brown Fat Phenotypic Switch Induced by Genetic and Environmental Activation of a Hypothalamic-Adipocyte Axis
- (2011) Lei Cao et al. Cell Metabolism
- Inhibition of myostatin protects against diet-induced obesity by enhancing fatty acid oxidation and promoting a brown adipose phenotype in mice
- (2011) C. Zhang et al. DIABETOLOGIA
- PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice
- (2011) Mei Tran et al. JOURNAL OF CLINICAL INVESTIGATION
- Mitochondrial Biogenesis in Kidney Disease
- (2011) J. M. Weinberg JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Fatty liver is associated with impaired activity of PPARγ-coactivator 1α (PGC1α) and mitochondrial biogenesis in mice
- (2011) Michal Aharoni-Simon et al. LABORATORY INVESTIGATION
- Expression and Function of Myostatin in Obesity, Diabetes, and Exercise Adaptation
- (2011) DAVID L. ALLEN et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Increases in mitochondrial biogenesis impair carcinogenesis at multiple levels
- (2011) Xiao Wang et al. Molecular Oncology
- Peroxisome proliferator-activated receptor- coactivator 1- (PGC1 ) is a metabolic regulator of intestinal epithelial cell fate
- (2011) I. D'Errico et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epicardial adipose tissue: emerging physiological, pathophysiological and clinical features
- (2011) Gianluca Iacobellis et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis
- (2010) Craig Brooks et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- PGC-1 Coactivators in Cardiac Development and Disease
- (2010) Glenn C. Rowe et al. CIRCULATION RESEARCH
- Peroxisome Proliferator-activated Receptor γ Coactivator 1α (PGC-1α) Promotes Skeletal Muscle Lipid Refuelingin Vivoby Activatingde NovoLipogenesis and the Pentose Phosphate Pathway
- (2010) Serge Summermatter et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Energy Metabolic Phenotype of the Cardiomyocyte During Development, Differentiation, and Postnatal Maturation
- (2010) Gary D Lopaschuk et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- PGC-1 regulates a HIF2 -dependent switch in skeletal muscle fiber types
- (2010) K. A. Rasbach et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of homocysteine homeostasis through the transcriptional coactivator PGC-1α
- (2009) Siming Li et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Dual modulation of both lipid oxidation and synthesis by peroxisome proliferator-activated receptor-γ coactivator-1α and -1β in cultured myotubes
- (2009) Daniel O. Espinoza et al. FASEB JOURNAL
- Uncoupling Protein-1 and Related Messenger Ribonucleic Acids in Human Epicardial and Other Adipose Tissues: Epicardial Fat Functioning as Brown Fat
- (2009) Harold S. Sacks et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models
- (2009) Craig Brooks et al. JOURNAL OF CLINICAL INVESTIGATION
- Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Interacts with the Androgen Receptor (AR) and Promotes Prostate Cancer Cell Growth by Activating the AR
- (2009) Masaki Shiota et al. MOLECULAR ENDOCRINOLOGY
- Epicardial and Pericardial Fat: Close, but Very Different
- (2009) Gianluca Iacobellis Obesity
- Myostatin Inhibition in Muscle, but Not Adipose Tissue, Decreases Fat Mass and Improves Insulin Sensitivity
- (2009) Tingqing Guo et al. PLoS One
- The transcriptional coactivator PGC-1α mediates exercise-induced angiogenesis in skeletal muscle
- (2009) Jessica Chinsomboon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epicardial Adipose Tissue Adiponectin Expression is Related to Intracoronary Adiponectin Levels
- (2008) G. Iacobellis et al. HORMONE AND METABOLIC RESEARCH
- Muscle-specific expression of PPARγ coactivator-1α improves exercise performance and increases peak oxygen uptake
- (2008) Jennifer A. Calvo et al. JOURNAL OF APPLIED PHYSIOLOGY
- Suppression of Lipopolysaccharide-stimulated Tumor Necrosis Factor-α Production by Adiponectin Is Mediated by Transcriptional and Post-transcriptional Mechanisms
- (2008) Pil-Hoon Park et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Paradoxical effects of increased expression of PGC-1 on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism
- (2008) C. S. Choi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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