Emerging insights into human health and NK cell biology from the study of NK cell deficiencies

Strategies to activate NK cells to prevent relapse and induce remission following hematopoietic stem cell transplantation

(2018) Sarah Cooley et al.   BLOOD

CTLA-4 regulates human Natural Killer cell effector functions

(2018) Vassilios Lougaris et al.   CLINICAL IMMUNOLOGY

Nanoscale Dynamism of Actin Enables Secretory Function in Cytolytic Cells

(2018) Alexandre F. Carisey et al.   CURRENT BIOLOGY

Transcription Factor IRF8 Orchestrates the Adaptive Natural Killer Cell Response

(2018) Nicholas M. Adams et al.   IMMUNITY

Innate Lymphoid Cell Development: A T Cell Perspective

(2018) Dylan E. Cherrier et al.   IMMUNITY

Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation

(2018) Venetia Bigley et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A RAB27A 5′ untranslated region structural variant associated with late-onset hemophagocytic lymphohistiocytosis and normal pigmentation

(2018) Bianca Tesi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations

(2018) Alexander Vargas-Hernández et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mutations in PI3K110δ cause impaired natural killer cell function partially rescued by rapamycin treatment

(2018) Raquel Ruiz-García et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Single Degranulations in NK Cells Can Mediate Target Cell Killing

(2018) Lavesh A. Gwalani et al.   JOURNAL OF IMMUNOLOGY

BiallelicRIPK1mutations in humans cause severe immunodeficiency, arthritis, and intestinal inflammation

(2018) Delphine Cuchet-Lourenço et al.   SCIENCE

Combined Immunodeficiency in Patients With Trichohepatoenteric Syndrome

(2018) Frédéric Vély et al.   Frontiers in Immunology

Phosphoinositide-3-Kinase Signaling in Human Natural Killer Cells: New Insights from Primary Immunodeficiency

(2018) Emily M. Mace   Frontiers in Immunology

Innate Lymphoid Cells: 10 Years On

(2018) Eric Vivier et al.   CELL

The Broad Spectrum of Human Natural Killer Cell Diversity

(2017) Aharon G. Freud et al.   IMMUNITY

An actin cytoskeletal barrier inhibits lytic granule release from natural killer cells in patients with Chediak-Higashi syndrome

(2017) Aleksandra Gil-Krzewska et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee Report on Inborn Errors of Immunity

(2017) Capucine Picard et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency

(2017) Julien Cottineau et al.   JOURNAL OF CLINICAL INVESTIGATION

CD56bright NK cells exhibit potent antitumor responses following IL-15 priming

(2017) Julia A. Wagner, Maximillian Rosario, Rizwan Romee, Melissa M. Berrien-Elliott, Stephanie E. Schneider, Jeffrey W. Leong, Ryan P. Sullivan, Brea A. Jewell, Michelle Becker-Hapak, Timothy Schappe, Sara Abdel-Latif, Aaron R. Ireland, Devika Jaishankar, Justin A. King, Ravi Vij, Dennis Clement, Jodie Goodridge, Karl-Johan Malmberg, Hing C. Wong, Todd A. Fehniger   JOURNAL OF CLINICAL INVESTIGATION

Geographic clonal tracking in macaques provides insights into HSPC migration and differentiation

(2017) Chuanfeng Wu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An Unbiased Linkage Approach Reveals That the p53 Pathway Is Coupled to NK Cell Maturation

(2017) Roxanne Collin et al.   JOURNAL OF IMMUNOLOGY

Of Mice, Dirty Mice, and Men: Using Mice To Understand Human Immunology

(2017) David Masopust et al.   JOURNAL OF IMMUNOLOGY

DNA damage tolerance in hematopoietic stem and progenitor cells in mice

(2017) Bas Pilzecker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mcm10: A Dynamic Scaffold at Eukaryotic Replication Forks

(2017) Ryan Baxley et al.   Genes

Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56bright NKG2A+++ Cells, and Yet Display Increased Degranulation and Higher Perforin Content

(2017) Kerry Dobbs et al.   Frontiers in Immunology

High-resolution phenotyping identifies NK cell subsets that distinguish healthy children from adults

(2017) Sanjana Mahapatra et al.   PLoS One

Association of GATA2 Deficiency With Severe Primary Epstein-Barr Virus (EBV) Infection and EBV-associated Cancers

(2016) Jeffrey I. Cohen et al.   CLINICAL INFECTIOUS DISEASES

A Progenitor Cell Expressing Transcription Factor RORγt Generates All Human Innate Lymphoid Cell Subsets

(2016) Steven D. Scoville et al.   IMMUNITY

A novel mutation in the POLE2 gene causing combined immunodeficiency

(2016) Francesco Frugoni et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

p85α is an intrinsic regulator of human natural killer cell effector functions

(2016) Vassilios Lougaris et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Chediak-Higashi syndrome: Lysosomal trafficking regulator domains regulate exocytosis of lytic granules but not cytokine secretion by natural killer cells

(2016) Aleksandra Gil-Krzewska et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Human innate lymphoid cells

(2016) Jenny Mjösberg et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Phosphatase and tensin homolog ( PTEN ) mutation can cause activated phosphatidylinositol 3-kinase δ syndrome–like immunodeficiency

(2016) Yuki Tsujita et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Expansion of inflammatory innate lymphoid cells in patients with common variable immune deficiency

(2016) Montserrat Cols et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A novel Rab27a mutation binds melanophilin, but not Munc13-4, causing immunodeficiency without albinism

(2016) Petra Netter et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

NK cells converge lytic granules to promote cytotoxicity and prevent bystander killing

(2016) Hsiang-Ting Hsu et al.   JOURNAL OF CELL BIOLOGY

Biallelic mutations in IRF8 impair human NK cell maturation and function

(2016) Emily M. Mace et al.   JOURNAL OF CLINICAL INVESTIGATION

The heterogeneity of human CD127+ innate lymphoid cells revealed by single-cell RNA sequencing

(2016) Åsa K Björklund et al.   NATURE IMMUNOLOGY

RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics

(2016) Elisabeth Salzer et al.   NATURE IMMUNOLOGY

Targeting natural killer cells in cancer immunotherapy

(2016) Camille Guillerey et al.   NATURE IMMUNOLOGY

Loss of B Cells in Patients with Heterozygous Mutations in IKAROS

(2016) Hye Sun Kuehn et al.   NEW ENGLAND JOURNAL OF MEDICINE

Biallelic JAK1 mutations in immunodeficient patient with mycobacterial infection

(2016) Davide Eletto et al.   Nature Communications

Human NK cell development requires CD56-mediated motility and formation of the developmental synapse

(2016) Emily M. Mace et al.   Nature Communications

Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans

(2016) Lisa L. Liu et al.   Cell Reports

NKp80 Defines a Critical Step during Human Natural Killer Cell Development

(2016) Aharon G. Freud et al.   Cell Reports

Chronic Infection Depletes Hematopoietic Stem Cells through Stress-Induced Terminal Differentiation

(2016) Katie A. Matatall et al.   Cell Reports

Genetic Causes of Human NK Cell Deficiency and Their Effect on NK Cell Subsets

(2016) Emily M. Mace et al.   Frontiers in Immunology

Human Circulating and Tissue-Resident CD56bright Natural Killer Cell Populations

(2016) Janine E. Melsen et al.   Frontiers in Immunology

A potential founder variant inCARMIL2/RLTPRin three Norwegian families with warts, molluscum contagiosum, and T-cell dysfunction

(2016) Hanne S. Sorte et al.   Molecular Genetics & Genomic Medicine

Cytomegalovirus Infection Drives Adaptive Epigenetic Diversification of NK Cells with Altered Signaling and Effector Function

(2015) Heinrich Schlums et al.   IMMUNITY

Epigenetic Modification and Antibody-Dependent Expansion of Memory-like NK Cells in Human Cytomegalovirus-Infected Individuals

(2015) Jaewon Lee et al.   IMMUNITY

Practical NK cell phenotyping and variability in healthy adults

(2015) Laura S. Angelo et al.   IMMUNOLOGIC RESEARCH

Ly49 receptors: evolution, genetic diversity, and impact on immunity

(2015) Mir Munir A. Rahim et al.   IMMUNOLOGICAL REVIEWS

Molecular mechanisms of functional natural killer deficiency in patients with partial DiGeorge syndrome

(2015) Peilin Zheng et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

β2-Microglobulin deficiency causes a complex immunodeficiency of the innate and adaptive immune system

(2015) Ömür Ardeniz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Defective natural killer–cell cytotoxic activity in NFKB2-mutated CVID-like disease

(2015) Vassilios Lougaris et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Insights into primary immune deficiency from quantitative microscopy

(2015) Emily M. Mace et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A homozygous mutation of RTEL1 in a child presenting with an apparently isolated natural killer cell deficiency

(2015) Suheir Hanna et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding

(2015) Valentina Cetica et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Long-Term Follow-up of STAT5B Deficiency in Three Argentinian Patients: Clinical and Immunological Features

(2015) Liliana Bezrodnik et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Immunodeficiency and Autoimmune Enterocolopathy Linked to NFAT5 Haploinsufficiency

(2015) Brigid S. Boland et al.   JOURNAL OF IMMUNOLOGY

Altered chemotactic response to CXCL12 in patients carrying GATA2 mutations

(2015) Anna Maciejewski-Duval et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Batf3 maintains autoactivation of Irf8 for commitment of a CD8α+ conventional DC clonogenic progenitor

(2015) Gary E Grajales-Reyes et al.   NATURE IMMUNOLOGY

Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections

(2015) Kerry Dobbs et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

(2015) S. Okada et al.   SCIENCE

Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality

(2015) Silvia Alvarez et al.   Nature Communications

Transcription of the activating receptor NKG2D in natural killer cells is regulated by STAT3 tyrosine phosphorylation

(2014) S. Zhu et al.   BLOOD

A nonsense mutation in IKBKB causes combined immunodeficiency

(2014) T. Mousallem et al.   BLOOD

Human innate lymphoid cells

(2014) M. D. Hazenberg et al.   BLOOD

Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease

(2014) J. M. Munneke et al.   BLOOD

RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis

(2014) James A. Rickard et al.   CELL

The RAG Recombinase Dictates Functional Heterogeneity and Cellular Fitness in Natural Killer Cells

(2014) Jenny M. Karo et al.   CELL

Clonal Tracking of Rhesus Macaque Hematopoiesis Highlights a Distinct Lineage Origin for Natural Killer Cells

(2014) Chuanfeng Wu et al.   Cell Stem Cell

Human RORγt+CD34+ Cells Are Lineage-Specified Progenitors of Group 3 RORγt+ Innate Lymphoid Cells

(2014) Elisa Montaldo et al.   IMMUNITY

Cell biological steps and checkpoints in accessing NK cell cytotoxicity

(2014) Emily M Mace et al.   IMMUNOLOGY AND CELL BIOLOGY

Compound Heterozygous CORO1A Mutations in Siblings with a Mucocutaneous-Immunodeficiency Syndrome of Epidermodysplasia Verruciformis-HPV, Molluscum Contagiosum and Granulomatous Tuberculoid Leprosy

(2014) Asbjorg Stray-Pedersen et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Heterozygous splice mutation inPIK3R1causes human immunodeficiency with lymphoproliferation due to dominant activation of PI3K

(2014) Carrie L. Lucas et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An Unusual CD56brightCD16low NK Cell Subset Dominates the Early Posttransplant Period following HLA-Matched Hematopoietic Stem Cell Transplantation

(2014) N. Dulphy et al.   JOURNAL OF IMMUNOLOGY

Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells

(2014) Johanna Flach et al.   NATURE

RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

(2014) Marius Dannappel et al.   NATURE

Combined immunodeficiency develops with age in Immunodeficiency-centromeric instability-facial anomalies syndrome 2 (ICF2)

(2014) Horst von Bernuth et al.   Orphanet Journal of Rare Diseases

Lytic immune synapse function requires filamentous actin deconstruction by Coronin 1A

(2014) E. M. Mace et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human natural killer cell development in secondary lymphoid tissues

(2014) Aharon G. Freud et al.   SEMINARS IN IMMUNOLOGY

Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity

(2014) Katharina L. Willmann et al.   Nature Communications

Distinct Migration and Contact Dynamics of Resting and IL-2-Activated Human Natural Killer Cells

(2014) Per E. Olofsson et al.   Frontiers in Immunology

The impact of ageing on natural killer cell function and potential consequences for health in older adults

(2013) Jon Hazeldine et al.   AGEING RESEARCH REVIEWS

Immunological profile of Fanconi anemia: A multicentric retrospective analysis of 61 patients

(2013) Elisabeth T. Korthof et al.   AMERICAN JOURNAL OF HEMATOLOGY

Mutations in GATA2 cause human NK cell deficiency with specific loss of the CD56bright subset

(2013) E. M. Mace et al.   BLOOD

Rapid activation receptor- or IL-2-induced lytic granule convergence in human natural killer cells requires Src, but not downstream signaling

(2013) A. M. James et al.   BLOOD

GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity

(2013) M. A. Spinner et al.   BLOOD

The evolution of cellular deficiency in GATA2 mutation

(2013) R. E. Dickinson et al.   BLOOD

Loss-of-function of the protein kinase C   (PKC ) causes a B-cell lymphoproliferative syndrome in humans

(2013) H. S. Kuehn et al.   BLOOD

Natural Killer Cells and Antifungal Host Response

(2013) Stanislaw Schmidt et al.   Clinical and Vaccine Immunology

Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity

(2013) Kevin Goudy et al.   CLINICAL IMMUNOLOGY

Germline mutations of regulator of telomere elongation helicase 1, RTEL1, in Dyskeratosis congenita

(2013) Bari J. Ballew et al.   HUMAN GENETICS

Human RTEL1 deficiency causes Hoyeraal–Hreidarsson syndrome with short telomeres and genome instability

(2013) Tangui Le Guen et al.   HUMAN MOLECULAR GENETICS

Defective actin accumulation impairs human natural killer cell function in patients with dedicator of cytokinesis 8 deficiency

(2013) Melissa C. Mizesko et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Whole-exome sequencing identifies Coronin-1A deficiency in 3 siblings with immunodeficiency and EBV-associated B-cell lymphoproliferation

(2013) Despina Moshous et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Natural killer cell deficiency

(2013) Jordan S. Orange   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome

(2013) Daniel Kotlarz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency

(2013) Carrie L Lucas et al.   NATURE IMMUNOLOGY

Severe Combined Immunodeficiency Resulting From Mutations in MTHFD1

(2013) M. D. Keller et al.   PEDIATRICS

Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal–Hreidarsson syndrome

(2013) Zhong Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphoinositide 3-Kinase   Gene Mutation Predisposes to Respiratory Infection and Airway Damage

(2013) I. Angulo et al.   SCIENCE

Mg2+ Regulates Cytotoxic Functions of NK and CD8 T Cells in Chronic EBV Infection Through NKG2D

(2013) B. Chaigne-Delalande et al.   SCIENCE

Genetic and Environmental Determinants of Human NK Cell Diversity Revealed by Mass Cytometry

(2013) A. Horowitz et al.   Science Translational Medicine

Location and cellular stages of natural killer cell development

(2013) Jianhua Yu et al.   TRENDS IN IMMUNOLOGY

Short Communication: NKG2C+ NK Cells Contribute to Increases in CD16+CD56− Cells in HIV Type 1+ Individuals with High Plasma Viral Load

(2012) John N.S. Gregson et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Loss of kindlin-3 alters the threshold for NK cell activation in human leukocyte adhesion deficiency-III

(2012) R. Gruda et al.   BLOOD

Exome sequencing reveals a pallidin mutation in a Hermansky-Pudlak-like primary immunodeficiency syndrome

(2012) R. Badolato et al.   BLOOD

Bilateral adrenal EBV-associated smooth muscle tumors in a child with a natural killer cell deficiency

(2012) R. K. Shaw et al.   BLOOD

Cytokine activation induces human memory-like NK cells

(2012) R. Romee et al.   BLOOD

Innate Lymphoid Cell Interactions with Microbiota: Implications for Intestinal Health and Disease

(2012) Gregory F. Sonnenberg et al.   IMMUNITY

Priming of Natural Killer Cells by Nonmucosal Mononuclear Phagocytes Requires Instructive Signals from Commensal Microbiota

(2012) Stephanie C. Ganal et al.   IMMUNITY

MCM4 mutation causes adrenal failure, short stature, and natural killer cell deficiency in humans

(2012) Claire R. Hughes et al.   JOURNAL OF CLINICAL INVESTIGATION

Evidence for a stepwise program of extrathymic T cell development within the human tonsil

(2012) Susan McClory et al.   JOURNAL OF CLINICAL INVESTIGATION

Human immunodeficiency-causing mutation defines CD16 in spontaneous NK cell cytotoxicity

(2012) Jennifer T. Grier et al.   JOURNAL OF CLINICAL INVESTIGATION

Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency

(2012) Laure Gineau et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis

(2012) Baptiste N. Jaeger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Agammaglobulinemia and absent B lineage cells in a patient lacking the p85α subunit of PI3K

(2012) Mary Ellen Conley et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A novel primary human immunodeficiency due to deficiency in the WASP-interacting protein WIP

(2012) Gaetana Lanzi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cold Urticaria, Immunodeficiency, and Autoimmunity Related toPLCG2Deletions

(2012) Michael J. Ombrello et al.   NEW ENGLAND JOURNAL OF MEDICINE

Defining Early Human NK Cell Developmental Stages in Primary and Secondary Lymphoid Tissues

(2012) Diana N. Eissens et al.   PLoS One

Overexpression of Methyl-CpG Binding Protein 2 Impairs TH1 Responses

(2012) T. Yang et al.   Science Translational Medicine

Mutations in ZBTB24 Are Associated with Immunodeficiency, Centromeric Instability, and Facial Anomalies Syndrome Type 2

(2011) Jessica C. de Greef et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Targeted disruption of Mcm10 causes defective embryonic cell proliferation and early embryo lethality

(2011) Han Jeong Lim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Phosphorylation of the myosin IIA tailpiece regulates single myosin IIA molecule association with lytic granules to promote NK-cell cytotoxicity

(2011) K. B. Sanborn et al.   BLOOD

NK cells can generate from precursors in the adult human liver

(2011) Viviana Moroso et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-2 induces a WAVE2-dependent pathway for actin reorganization that enables WASp-independent human NK cell function

(2011) Jordan S. Orange et al.   JOURNAL OF CLINICAL INVESTIGATION

Antiviral and Regulatory T Cell Immunity in a Patient with Stromal Interaction Molecule 1 Deficiency

(2011) S. Fuchs et al.   JOURNAL OF IMMUNOLOGY

Human NK Cells Proliferate and Die In Vivo More Rapidly than T Cells in Healthy Young and Elderly Adults

(2011) C. T. Lutz et al.   JOURNAL OF IMMUNOLOGY

Second messenger role for Mg2+ revealed by human T-cell immunodeficiency

(2011) Feng-Yen Li et al.   NATURE

IRF8Mutations and Human Dendritic-Cell Immunodeficiency

(2011) Sophie Hambleton et al.   NEW ENGLAND JOURNAL OF MEDICINE

Congenital pancytopenia and absence of B lymphocytes in a neonate with a mutation in the ikaros gene

(2011) Frederick D. Goldman et al.   PEDIATRIC BLOOD & CANCER

ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis

(2011) A. Maul-Pavicic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expansion of a unique CD57+NKG2Chi natural killer cell subset during acute human cytomegalovirus infection

(2011) S. Lopez-Verges et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD34+ hematopoietic precursors are present in human decidua and differentiate into natural killer cells upon interaction with stromal cells

(2011) P. Vacca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unconventional Repertoire Profile Is Imprinted during Acute Chikungunya Infection for Natural Killer Cells Polarization toward Cytotoxicity

(2011) Caroline Petitdemange et al.   PLoS Pathogens

A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development

(2010) E. Eckelhart et al.   BLOOD

Latent herpesvirus infection arms NK cells

(2010) D. W. White et al.   BLOOD

XIAP deficiency: a unique primary immunodeficiency best classified as X-linked familial hemophagocytic lymphohistiocytosis and not as X-linked lymphoproliferative disease

(2010) R. A. Marsh et al.   BLOOD

Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus

(2010) Niklas K. Björkström et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Rapid Lytic Granule Convergence to the MTOC in Natural Killer Cells Is Dependent on Dynein But Not Cytolytic Commitment

(2010) Ashley N. Mentlik et al.   MOLECULAR BIOLOGY OF THE CELL

Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection

(2010) Megan T. Baldridge et al.   NATURE

Revisiting human natural killer cell subset function revealed cytolytic CD56dimCD16+ NK cells as rapid producers of abundant IFN-  on activation

(2010) A. De Maria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic HIV-1 viremia reverses NKG2A/NKG2C ratio on natural killer cells in patients with human cytomegalovirus co-infection

(2009) Enrico Brunetta et al.   AIDS

Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity

(2009) S. M. Wood et al.   BLOOD

Comèl-Netherton syndrome defined as primary immunodeficiency

(2009) Ellen D. Renner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Girls homozygous for an IL-2–inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation

(2009) Kirsten Huck et al.   JOURNAL OF CLINICAL INVESTIGATION

The IRF Family Transcription Factors in Immunity and Oncogenesis

(2008) Tomohiko Tamura et al.   Annual Review of Immunology

A role for interleukin-12/23 in the maturation of human natural killer and CD56+ T cells in vivo

(2008) S. Guia et al.   BLOOD

Human natural killer cells

(2008) M. A. Caligiuri   BLOOD

Mouse fetal and embryonic liver cells differentiate human umbilical cord blood progenitors into CD56-negative natural killer cell precursors in the absence of interleukin-15

(2008) Valarie McCullar et al.   EXPERIMENTAL HEMATOLOGY

A Novel Variant of Familial Glucocorticoid Deficiency Prevalent among the Irish Traveler Population

(2008) Stephen M. P. O'Riordan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

(2008) Nicholas D. Huntington et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human adenylate kinase 2 deficiency causes a profound hematopoietic defect associated with sensorineural deafness

(2008) Chantal Lagresle-Peyrou et al.   NATURE GENETICS

The actin regulator coronin 1A is mutant in a thymic egress–deficient mouse strain and in a patient with severe combined immunodeficiency

(2008) Lawrence R Shiow et al.   NATURE IMMUNOLOGY

Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication

(2008) Arkaitz Ibarra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA