BiallelicRIPK1mutations in humans cause severe immunodeficiency, arthritis, and intestinal inflammation

The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies

(2017) Aziz Bousfiha et al.   JOURNAL OF CLINICAL IMMUNOLOGY

RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4

(2016) Malek Najjar et al.   IMMUNITY

Human Monocytes Engage an Alternative Inflammasome Pathway

(2016) Moritz M. Gaidt et al.   IMMUNITY

RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation

(2016) Juan Lin et al.   NATURE

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

T cell–intrinsic ASC critically promotes TH17-mediated experimental autoimmune encephalomyelitis

(2016) Bradley N Martin et al.   NATURE IMMUNOLOGY

T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells

(2016) G. Arbore et al.   SCIENCE

Distinct NF-κB and MAPK Activation Thresholds Uncouple Steady-State Microbe Sensing from Anti-pathogen Inflammatory Responses

(2016) Rachel A. Gottschalk et al.   Cell Systems

Necroptosis and its role in inflammation

(2015) Manolis Pasparakis et al.   NATURE

Interleukin-1 function and role in rheumatic disease

(2015) Georg Schett et al.   Nature Reviews Rheumatology

Role of necroptosis in the pathogenesis of solid organ injury

(2015) H Zhao et al.   Cell Death & Disease

RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis

(2014) James A. Rickard et al.   CELL

All Human EF1α Promoters Are Not Equal: Markedly Affect Gene Expression in Constructs from Different Sources

(2014) Changyu Zheng et al.   International Journal of Medical Sciences

Cutting Edge: RIPK1 Kinase Inactive Mice Are Viable and Protected from TNF-Induced Necroptosis In Vivo

(2014) Apostolos Polykratis et al.   JOURNAL OF IMMUNOLOGY

RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis

(2014) Nozomi Takahashi et al.   NATURE

RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

(2014) Marius Dannappel et al.   NATURE

RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition

(2014) W. J. Kaiser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis

(2014) Justine E. Roderick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis

(2014) K. Newton et al.   SCIENCE

Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death

(2013) Dimitry Ofengeim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A robust model for read count data in exome sequencing experiments and implications for copy number variant calling

(2012) Vincent Plagnol et al.   BIOINFORMATICS

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

(2012) Liming Sun et al.   CELL

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Paediatric Reference Values for the Peripheral T cell Compartment

(2012) E. J. H. Schatorjé et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Genetics and pathogenesis of inflammatory bowel disease

(2011) Bernard Khor et al.   NATURE

Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

(2009) D.-W. Zhang et al.   SCIENCE

DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome

(2008) Timothy J. Ley et al.   NATURE